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CY1107274T1 - Παραγωγα αλφα-αμινοαμιδιου χρησιμα σαν παραγοντες κατα της ημικρανιας - Google Patents

Παραγωγα αλφα-αμινοαμιδιου χρησιμα σαν παραγοντες κατα της ημικρανιας

Info

Publication number
CY1107274T1
CY1107274T1 CY20081100099T CY081100099T CY1107274T1 CY 1107274 T1 CY1107274 T1 CY 1107274T1 CY 20081100099 T CY20081100099 T CY 20081100099T CY 081100099 T CY081100099 T CY 081100099T CY 1107274 T1 CY1107274 T1 CY 1107274T1
Authority
CY
Cyprus
Prior art keywords
alpha
derivatives useful
aminoamide derivatives
migraine agents
migraine
Prior art date
Application number
CY20081100099T
Other languages
English (en)
Inventor
Patricia Salvati
Marcello Calabresi
Luciano Dho
Orietta Veneroni
Piero Melloni
Original Assignee
Newron Pharmaceuticals S.P.A.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Newron Pharmaceuticals S.P.A. filed Critical Newron Pharmaceuticals S.P.A.
Publication of CY1107274T1 publication Critical patent/CY1107274T1/el

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/16—Amides, e.g. hydroxamic acids
    • A61K31/165—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/06—Antimigraine agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]

Landscapes

  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Engineering & Computer Science (AREA)
  • Pain & Pain Management (AREA)
  • Neurosurgery (AREA)
  • Rheumatology (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Heterocyclic Compounds Containing Sulfur Atoms (AREA)

Abstract

Αποκαλύπτονται παράγωγα α-αμινοαμιδίου χρήσιμα σαν παράγοντες κατά της ημικρανίας, ιδιαιτέρως για τη θεραπεία καταστάσεων κεφαλαλγίας, όπως ημικρανίας, εντοπισμένης κεφαλαλγίας ή άλλης σοβαρής κεφαλαλγίας Οι παράγοντες κατά της ημικρανίας της εφεύρεσης είναι ικανοί να μειώσουν ή ακόμη και να σταματήσουν τον πόνο που προέρχεται από τέτοιες καταστάσεις χωρίς σχεδόν οποιεσδήποτε παρενέργειες.
CY20081100099T 2003-01-16 2008-01-28 Παραγωγα αλφα-αμινοαμιδιου χρησιμα σαν παραγοντες κατα της ημικρανιας CY1107274T1 (el)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP03000921A EP1438956A1 (en) 2003-01-16 2003-01-16 Alpha-aminoamide derivatives useful as antimigraine agents
EP03772344A EP1585510B1 (en) 2003-01-16 2003-11-18 Alpha-aminoamide derivatives useful as antimigraine agents

Publications (1)

Publication Number Publication Date
CY1107274T1 true CY1107274T1 (el) 2012-11-21

Family

ID=32524140

Family Applications (1)

Application Number Title Priority Date Filing Date
CY20081100099T CY1107274T1 (el) 2003-01-16 2008-01-28 Παραγωγα αλφα-αμινοαμιδιου χρησιμα σαν παραγοντες κατα της ημικρανιας

Country Status (21)

Country Link
US (2) US7709523B2 (el)
EP (2) EP1438956A1 (el)
JP (1) JP4885455B2 (el)
KR (1) KR101049694B1 (el)
CN (1) CN100418517C (el)
AT (1) ATE380026T1 (el)
AU (1) AU2003279399B8 (el)
BR (1) BRPI0317795B8 (el)
CA (1) CA2510514C (el)
CY (1) CY1107274T1 (el)
DE (1) DE60317935T2 (el)
DK (1) DK1585510T3 (el)
ES (1) ES2295658T3 (el)
HK (1) HK1086487A1 (el)
MX (1) MXPA05007339A (el)
NO (1) NO333610B1 (el)
NZ (1) NZ541117A (el)
PT (1) PT1585510E (el)
RU (1) RU2336077C2 (el)
SI (1) SI1585510T1 (el)
WO (1) WO2004062655A1 (el)

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GB9727523D0 (en) 1997-12-31 1998-02-25 Pharmacia & Upjohn Spa Alpha-aminoamide derivatives useful as analgesic agents
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JP5042625B2 (ja) * 2003-08-25 2012-10-03 ニューロン・ファーマシューティカルズ・ソチエタ・ペル・アチオニ 抗炎症剤として有用なα−アミノアミド誘導体
DK1809271T5 (da) * 2004-09-10 2010-12-06 Newron Pharm Spa Anvendelse af (R)-(halogenbenzyloxy)benzylaminopropanamider som natrium- og/eller calciumkanalselektive modulatorer
CN101309909B (zh) 2005-12-22 2012-11-14 纽朗制药有限公司 作为钙和/或钠通道调节剂的2-苯基乙基氨基衍生物
PT2474521T (pt) 2006-06-19 2016-11-10 Newron Pharm Spa 2-[4-(3- e 2-fluorobenziloxi)benzilamino]propanamidas de grau de pureza elevado para utilização como medicamentos e formulações farmacêuticas que as contêm
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PL2155663T3 (pl) 2007-06-15 2018-06-29 Newron Pharmaceuticals S.P.A. Podstawione pochodne 2-[2-(fenylo)etyloamino]alkanoamidu oraz ich zastosowanie jako modulatorów kanałów sodowych i (lub) wapniowych
SI2229351T1 (en) 2007-12-11 2018-02-28 Newron Pharmaceuticals S.P.A. PROCEDURE FOR PREPARATION OF 2- (4- (3-OR 2-FLUOROBENYLOXYL) BENZYLAMINO) PROPANAMIDES WITH A HIGH PURITY Purity
EP2314569A1 (en) 2009-10-22 2011-04-27 Merck Patent GmbH Novel polymorphic forms of (S)-2-[4-(3-Fluoro-benzyloxy)-benzylamino]-propionamide mesylate salt and processes of manufacturing thereof
MX342697B (es) 2010-04-27 2016-10-10 Newron Pharmaceuticals S P A * Proceso para produccion de sales de metanosulfonato de ralfinamida o sus enantiomeros r.
KR101705718B1 (ko) * 2013-12-30 2017-02-14 이화여자대학교 산학협력단 신규한 아미드 유도체 또는 이의 약학적으로 허용가능한 염, 이의 제조방법 및 이를 포함하는 통증의 예방 또는 치료용 약학적 조성물
CN107522654B (zh) * 2016-06-21 2020-09-01 中国人民解放军军事医学科学院毒物药物研究所 新的α-氨基酰胺衍生物及其医药用途
WO2019205147A1 (zh) * 2018-04-28 2019-10-31 上海璃道医药科技有限公司 包含苯并含氧脂肪环结构的氨基乙酰胺类化合物及其用途
CN112716927B (zh) * 2020-10-12 2022-10-14 复旦大学 α-氨基酰胺类化合物及其制备方法与应用

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Also Published As

Publication number Publication date
US20100267835A1 (en) 2010-10-21
CA2510514A1 (en) 2004-07-29
NO333610B1 (no) 2013-07-22
HK1086487A1 (en) 2006-09-22
KR20050094852A (ko) 2005-09-28
BRPI0317795B1 (pt) 2019-04-02
ATE380026T1 (de) 2007-12-15
RU2336077C2 (ru) 2008-10-20
ES2295658T3 (es) 2008-04-16
EP1438956A1 (en) 2004-07-21
MXPA05007339A (es) 2005-09-30
KR101049694B1 (ko) 2011-07-19
SI1585510T1 (sl) 2008-04-30
NO20053780L (no) 2005-10-13
US20060079570A1 (en) 2006-04-13
RU2005125919A (ru) 2006-01-10
EP1585510B1 (en) 2007-12-05
AU2003279399B2 (en) 2008-11-27
BRPI0317795B8 (pt) 2021-05-25
AU2003279399A1 (en) 2004-08-10
JP2006514060A (ja) 2006-04-27
DK1585510T3 (da) 2008-02-25
NO20053780D0 (no) 2005-08-09
DE60317935D1 (de) 2008-01-17
CN1738611A (zh) 2006-02-22
NZ541117A (en) 2008-02-29
US7709523B2 (en) 2010-05-04
BR0317795A (pt) 2005-11-22
AU2003279399B8 (en) 2009-01-29
CA2510514C (en) 2011-07-26
DE60317935T2 (de) 2008-11-27
JP4885455B2 (ja) 2012-02-29
EP1585510A1 (en) 2005-10-19
CN100418517C (zh) 2008-09-17
PT1585510E (pt) 2008-02-28
WO2004062655A1 (en) 2004-07-29

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