HK1065818A1 - Supersecretable peptides, processes for their production, and parallel improvement of the secreted form of one or more other polypeptides - Google Patents

Supersecretable peptides, processes for their production, and parallel improvement of the secreted form of one or more other polypeptides

Info

Publication number: HK1065818A1
Authority: HK; Hong Kong
Prior art keywords: protein; dna sequence; codon; lys; arg
Prior art date: 2001-02-20

Application number

HK04108554.7A

Other languages

English (en)

Inventor

Paul Habermann

Original Assignee

Sanofi Aventis Deutschland

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2001-02-20

Filing date

2004-11-01

Publication date

2005-03-04

2004-11-01 Application filed by Sanofi Aventis Deutschland filed Critical Sanofi Aventis Deutschland

2005-03-04 Publication of HK1065818A1 publication Critical patent/HK1065818A1/xx

Classifications

- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
- C12N15/62—DNA sequences coding for fusion proteins
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/81—Protease inhibitors
- C07K14/815—Protease inhibitors from leeches, e.g. hirudin, eglin
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/575—Hormones
- C07K14/62—Insulins
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/80—Vectors or expression systems specially adapted for eukaryotic hosts for fungi
- C12N15/81—Vectors or expression systems specially adapted for eukaryotic hosts for fungi for yeasts
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P21/00—Preparation of peptides or proteins
- C12P21/02—Preparation of peptides or proteins having a known sequence of two or more amino acids, e.g. glutathione
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/01—Fusion polypeptide containing a localisation/targetting motif
- C07K2319/02—Fusion polypeptide containing a localisation/targetting motif containing a signal sequence

Landscapes

Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Chemical & Material Sciences (AREA)
Genetics & Genomics (AREA)
Organic Chemistry (AREA)
Engineering & Computer Science (AREA)
Zoology (AREA)
Molecular Biology (AREA)
Wood Science & Technology (AREA)
Biotechnology (AREA)
General Health & Medical Sciences (AREA)
General Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Biomedical Technology (AREA)
Biochemistry (AREA)
Biophysics (AREA)
Microbiology (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Physics & Mathematics (AREA)
Mycology (AREA)
Gastroenterology & Hepatology (AREA)
Medicinal Chemistry (AREA)
Plant Pathology (AREA)
Toxicology (AREA)
Endocrinology (AREA)
Diabetes (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Tropical Medicine & Parasitology (AREA)
Preparation Of Compounds By Using Micro-Organisms (AREA)
Peptides Or Proteins (AREA)
Micro-Organisms Or Cultivation Processes Thereof (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Enzymes And Modification Thereof (AREA)

HK04108554.7A 2001-02-20 2004-11-01 Supersecretable peptides, processes for their production, and parallel improvement of the secreted form of one or more other polypeptides HK1065818A1 (en)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
DE10108100A DE10108100A1 (de)	2001-02-20	2001-02-20	Verwendung supersekretierbarer Peptide in Verfahren zu deren Herstellung und paralleler Verbesserung der Exportate eines oder mehrerer anderer Polypeptide von Interesse
PCT/EP2002/001306 WO2002066628A2 (en)	2001-02-20	2002-02-08	Supersecretable peptides, processes for their production, and parallel improvement of the secreted form of one or more other polypeptides

Publications (1)

Publication Number	Publication Date
HK1065818A1 true HK1065818A1 (en)	2005-03-04

Family

ID=7674831

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
HK04108554.7A HK1065818A1 (en)	2001-02-20	2004-11-01	Supersecretable peptides, processes for their production, and parallel improvement of the secreted form of one or more other polypeptides

Country Status (21)

Country	Link
EP (1)	EP1364030B1 (ja)
JP (1)	JP4243103B2 (ja)
KR (1)	KR100858008B1 (ja)
CN (1)	CN100575493C (ja)
AT (1)	ATE320498T1 (ja)
AU (1)	AU2002247696B2 (ja)
BR (1)	BR0207385A (ja)
CA (1)	CA2438935C (ja)
CY (1)	CY1105696T1 (ja)
DE (2)	DE10108100A1 (ja)
DK (1)	DK1364030T3 (ja)
ES (1)	ES2258619T3 (ja)
HK (1)	HK1065818A1 (ja)
IL (1)	IL157415A0 (ja)
MX (1)	MXPA03007115A (ja)
NO (1)	NO331375B1 (ja)
NZ (1)	NZ527641A (ja)
PE (1)	PE20020875A1 (ja)
PT (1)	PT1364030E (ja)
WO (1)	WO2002066628A2 (ja)
ZA (1)	ZA200305867B (ja)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
BRPI0409554A (pt) *	2003-04-04	2006-04-25	Univ Lausanne	peptacorpo de fusão isolado e recombinante, seqüência de dna, vetor, célula hospedeira, composição farmacêutica e seu uso, kits, método para a produção do peptacorpo de fusão e seqüência de intensificador
DE102006031955A1 (de)	2006-07-11	2008-01-17	Sanofi-Aventis Deutschland Gmbh	Verfahren zur Herstellung von Insulinanaloga mit dibasischem B-Kettenende
DE102006031962A1 (de)	2006-07-11	2008-01-17	Sanofi-Aventis Deutschland Gmbh	Amidiertes Insulin Glargin
PT2349324T (pt)	2008-10-17	2017-12-06	Sanofi Aventis Deutschland	Combinação de uma insulina e de um agonista do glp-1
PE20121362A1 (es)	2009-11-13	2012-10-17	Sanofi Aventis Deutschland	Composicion farmaceutica que comprende despro36exendina-4(1-39)-lys6-nh2, insulina gly(a21)-arg(b31)-arg(b32) y metionina
US9707176B2 (en)	2009-11-13	2017-07-18	Sanofi-Aventis Deutschland Gmbh	Pharmaceutical composition comprising a GLP-1 agonist and methionine
PL2611458T3 (pl)	2010-08-30	2017-02-28	Sanofi-Aventis Deutschland Gmbh	Zastosowanie AVE0010 do produkcji leku do leczenia cukrzycy typu 2
US9821032B2 (en)	2011-05-13	2017-11-21	Sanofi-Aventis Deutschland Gmbh	Pharmaceutical combination for improving glycemic control as add-on therapy to basal insulin
BR112014004726A2 (pt)	2011-08-29	2017-04-04	Sanofi Aventis Deutschland	combinação farmacêutica para uso no controle glicêmico em pacientes de diabetes tipo 2
AR087744A1 (es)	2011-09-01	2014-04-16	Sanofi Aventis Deutschland	Composicion farmaceutica para uso en el tratamiento de una enfermedad neurodegenerativa
ES2949095T3 (es)	2014-12-12	2023-09-25	Sanofi Aventis Deutschland	Formulación de relación fija de insulina glargina/lixisenatida
TWI748945B (zh)	2015-03-13	2021-12-11	德商賽諾菲阿凡提斯德意志有限公司	第２型糖尿病病患治療
TW201705975A (zh)	2015-03-18	2017-02-16	賽諾菲阿凡提斯德意志有限公司	第２型糖尿病病患之治療
CN108866205A (zh) *	2018-07-25	2018-11-23	中国食品药品检定研究院	基于分子生物学方法鉴别菲牛蛭的特异性引物

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
ATE101620T1 (de) *	1988-06-23	1994-03-15	Hoechst Ag	Mini-proinsulin, seine herstellung und verwendung.
GB8927722D0 (en) *	1989-12-07	1990-02-07	British Bio Technology	Proteins and nucleic acids
FI92601C (fi)	1992-03-11	1994-12-12	Marja Makarow	Menetelmä hyötyproteiinien erittämiseksi hiivoista

2001
- 2001-02-20 DE DE10108100A patent/DE10108100A1/de not_active Withdrawn
2002
- 2002-02-06 PE PE2002000083A patent/PE20020875A1/es not_active Application Discontinuation
- 2002-02-08 AT AT02716745T patent/ATE320498T1/de active
- 2002-02-08 EP EP02716745A patent/EP1364030B1/en not_active Expired - Lifetime
- 2002-02-08 NZ NZ527641A patent/NZ527641A/en not_active IP Right Cessation
- 2002-02-08 DK DK02716745T patent/DK1364030T3/da active
- 2002-02-08 JP JP2002566335A patent/JP4243103B2/ja not_active Expired - Fee Related
- 2002-02-08 PT PT02716745T patent/PT1364030E/pt unknown
- 2002-02-08 ES ES02716745T patent/ES2258619T3/es not_active Expired - Lifetime
- 2002-02-08 AU AU2002247696A patent/AU2002247696B2/en not_active Ceased
- 2002-02-08 WO PCT/EP2002/001306 patent/WO2002066628A2/en active IP Right Grant
- 2002-02-08 CN CN02806848A patent/CN100575493C/zh not_active Expired - Fee Related
- 2002-02-08 MX MXPA03007115A patent/MXPA03007115A/es active IP Right Grant
- 2002-02-08 IL IL15741502A patent/IL157415A0/xx not_active IP Right Cessation
- 2002-02-08 BR BR0207385-4A patent/BR0207385A/pt not_active IP Right Cessation
- 2002-02-08 DE DE60209883T patent/DE60209883T2/de not_active Expired - Lifetime
- 2002-02-08 CA CA2438935A patent/CA2438935C/en not_active Expired - Fee Related
- 2002-02-08 KR KR1020037010738A patent/KR100858008B1/ko not_active IP Right Cessation
2003
- 2003-07-30 ZA ZA200305867A patent/ZA200305867B/en unknown
- 2003-08-19 NO NO20033671A patent/NO331375B1/no not_active IP Right Cessation
2004
- 2004-11-01 HK HK04108554.7A patent/HK1065818A1/xx not_active IP Right Cessation
2006
- 2006-06-07 CY CY20061100751T patent/CY1105696T1/el unknown

Also Published As

Publication number	Publication date
IL157415A0 (en)	2004-03-28
ES2258619T3 (es)	2006-09-01
CN1527882A (zh)	2004-09-08
CN100575493C (zh)	2009-12-30
NO331375B1 (no)	2011-12-12
DE60209883D1 (de)	2006-05-11
PE20020875A1 (es)	2002-10-31
DK1364030T3 (da)	2006-07-17
MXPA03007115A (es)	2003-11-18
WO2002066628A3 (en)	2002-11-14
BR0207385A (pt)	2004-02-10
NZ527641A (en)	2005-03-24
DE60209883T2 (de)	2006-09-07
JP4243103B2 (ja)	2009-03-25
EP1364030A2 (en)	2003-11-26
EP1364030B1 (en)	2006-03-15
WO2002066628A2 (en)	2002-08-29
PT1364030E (pt)	2006-05-31
NO20033671L (no)	2003-10-17
NO20033671D0 (no)	2003-08-19
DE10108100A1 (de)	2002-08-29
ATE320498T1 (de)	2006-04-15
KR20030074832A (ko)	2003-09-19
ZA200305867B (en)	2004-06-29
JP2004518442A (ja)	2004-06-24
CA2438935A1 (en)	2002-08-29
KR100858008B1 (ko)	2008-09-11
AU2002247696B2 (en)	2006-10-12
CY1105696T1 (el)	2010-12-22
CA2438935C (en)	2012-01-24

Publication	Publication Date	Title
CY1105696T1 (el)	2010-12-22	Υπερεκκρινομενα πεπτιδια, διεργασιες για την παραγωγη τους και παραλληλη βελτιωση του εκκρινομενου ειδους ενος ή περισσοτερων αλλων πεπτιδιων
US5635371A (en)	1997-06-03	Chemical method for selective modification of the N- and/or C-terminal amino acid α-carbon reactive group of a recombinant polypeptide or a portion thereof
CY1106274T1 (el)	2011-10-12	Χρηση πρωτεϊνων συντηξης των οποιων το ν-τελικο τμημα ειναι ενα παραγωγο ιρουδινης για την παραγωγη ανασυνδυασμενων πρωτεϊνων μεσω εκκρισης απο ζυμομυκητα
NO965411L (no)	1997-02-14	N-terminalt forlengede proteiner uttrykt i gjær
ATE421977T1 (de)	2009-02-15	Reinigung von peptiden unter verwendung von metall-ion-affinitätschromatographie
JP2006501818A5 (ja)	2006-08-03
JP2010265287A (ja)	2010-11-25	ペプチドアミド化方法
DE69739013D1 (de)	2008-11-13	Verfahren zur Herstellung sekretorischer KEX2-Derivate
MX9701720A (es)	1997-06-28	Proceso para la fabricacion de una palidipina modificada, inhibidora de la agregacion plaquetaria inducida por colageno.
US5656456A (en)	1997-08-12	Chemical method for selective modification of the N- and/or C-terminal amino acid α-carbon reactive group of a recombinant polypeptide or a portion thereof
Loh et al.	1993	Proteolytic processing of prohormones and proneuropeptides
JP5909812B2 (ja)	2016-04-27	生物的に生成される環状アフィニティータグ
ES2316588T3 (es)	2009-04-16	Metodo para hacer polipeptidos acilados.
GR3016981T3 (en)	1995-11-30	Signal peptide and DNA sequences coding thereof.
WO2004011599A2 (en)	2004-02-05	Polypeptide cleavage process

Legal Events

Date	Code	Title	Description
2015-09-04	PC	Patent ceased (i.e. patent has lapsed due to the failure to pay the renewal fee)	Effective date: 20150208