HK1045267A1 - 供治療葡萄糖代謝失調的方法及試劑 - Google Patents
供治療葡萄糖代謝失調的方法及試劑Info
- Publication number
- HK1045267A1 HK1045267A1 HK02106949.7A HK02106949A HK1045267A1 HK 1045267 A1 HK1045267 A1 HK 1045267A1 HK 02106949 A HK02106949 A HK 02106949A HK 1045267 A1 HK1045267 A1 HK 1045267A1
- Authority
- HK
- Hong Kong
- Prior art keywords
- methods
- reagents
- metabolic disorders
- glucose metabolic
- treating glucose
- Prior art date
Links
- 238000000034 method Methods 0.000 title abstract 3
- 239000003153 chemical reaction reagent Substances 0.000 title 1
- 208000018914 glucose metabolism disease Diseases 0.000 title 1
- WQZGKKKJIJFFOK-GASJEMHNSA-N Glucose Natural products OC[C@H]1OC(O)[C@H](O)[C@@H](O)[C@@H]1O WQZGKKKJIJFFOK-GASJEMHNSA-N 0.000 abstract 1
- 230000001594 aberrant effect Effects 0.000 abstract 1
- 201000010099 disease Diseases 0.000 abstract 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 1
- 230000002708 enhancing effect Effects 0.000 abstract 1
- 239000008103 glucose Substances 0.000 abstract 1
- 230000004153 glucose metabolism Effects 0.000 abstract 1
- 210000004153 islets of langerhan Anatomy 0.000 abstract 1
- 230000003389 potentiating effect Effects 0.000 abstract 1
- 238000002560 therapeutic procedure Methods 0.000 abstract 1
- 208000001072 type 2 diabetes mellitus Diseases 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/22—Hormones
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
- A01K67/00—Rearing or breeding animals, not otherwise provided for; New or modified breeds of animals
- A01K67/027—New or modified breeds of vertebrates
- A01K67/0275—Genetically modified vertebrates, e.g. transgenic
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/22—Hormones
- A61K38/26—Glucagons
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/22—Hormones
- A61K38/28—Insulins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/18—Drugs for disorders of the alimentary tract or the digestive system for pancreatic disorders, e.g. pancreatic enzymes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/48—Drugs for disorders of the endocrine system of the pancreatic hormones
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/48—Drugs for disorders of the endocrine system of the pancreatic hormones
- A61P5/50—Drugs for disorders of the endocrine system of the pancreatic hormones for increasing or potentiating the activity of insulin
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
- G01N33/5008—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
- G01N33/5044—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics involving specific cell types
- G01N33/507—Pancreatic cells
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
- A01K2217/00—Genetically modified animals
- A01K2217/05—Animals comprising random inserted nucleic acids (transgenic)
- A01K2217/054—Animals comprising random inserted nucleic acids (transgenic) inducing loss of function
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Diabetes (AREA)
- Immunology (AREA)
- Endocrinology (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Zoology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Hematology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Cell Biology (AREA)
- Gastroenterology & Hepatology (AREA)
- Epidemiology (AREA)
- Biomedical Technology (AREA)
- Obesity (AREA)
- Urology & Nephrology (AREA)
- Biotechnology (AREA)
- Molecular Biology (AREA)
- Environmental Sciences (AREA)
- Biodiversity & Conservation Biology (AREA)
- Analytical Chemistry (AREA)
- Toxicology (AREA)
- Tropical Medicine & Parasitology (AREA)
- Microbiology (AREA)
- Animal Husbandry (AREA)
- Emergency Medicine (AREA)
- Food Science & Technology (AREA)
- Physics & Mathematics (AREA)
- Pathology (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US11957799P | 1999-02-10 | 1999-02-10 | |
PCT/US2000/003391 WO2000047219A2 (en) | 1999-02-10 | 2000-02-10 | Methods and reagents for treating glucose metabolic disorders |
Publications (1)
Publication Number | Publication Date |
---|---|
HK1045267A1 true HK1045267A1 (zh) | 2002-11-22 |
Family
ID=22385149
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
HK02106949.7A HK1045267A1 (zh) | 1999-02-10 | 2002-09-24 | 供治療葡萄糖代謝失調的方法及試劑 |
Country Status (12)
Country | Link |
---|---|
US (1) | US7396809B1 (zh) |
EP (1) | EP1189629B1 (zh) |
JP (3) | JP2003518914A (zh) |
AT (1) | ATE482717T1 (zh) |
AU (2) | AU779745C (zh) |
CA (1) | CA2360324C (zh) |
DE (1) | DE60045030D1 (zh) |
DK (1) | DK1189629T3 (zh) |
ES (1) | ES2353728T3 (zh) |
HK (1) | HK1045267A1 (zh) |
IL (2) | IL144703A (zh) |
WO (1) | WO2000047219A2 (zh) |
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US7048906B2 (en) | 1995-05-17 | 2006-05-23 | Cedars-Sinai Medical Center | Methods of diagnosing and treating small intestinal bacterial overgrowth (SIBO) and SIBO-related conditions |
JP2003518914A (ja) | 1999-02-10 | 2003-06-17 | キュリス インコーポレイテッド | グルコース代謝障害を治療する方法および試薬 |
US7745216B2 (en) | 1999-02-10 | 2010-06-29 | Curis, Inc. | Methods and reagents for treating glucose metabolic disorders |
AU2007200224B2 (en) * | 2000-12-14 | 2009-10-01 | Amylin Pharmaceuticals, Llc | Peptide YY and peptide YY agonists for treatment of metabolic disorders |
EP1349563B1 (en) * | 2000-12-14 | 2009-12-02 | Amylin Pharmaceuticals, Inc. | Peptide pyy[3-36] for treatment of metabolic disorders |
GB0109146D0 (en) * | 2001-04-11 | 2001-05-30 | Ferring Bv | Treatment of type 2 diabetes |
JP4975221B2 (ja) * | 2001-06-01 | 2012-07-11 | 協和メデックス株式会社 | α−アミラーゼ活性測定用試薬と測定方法 |
AU2002317599B2 (en) | 2001-07-31 | 2008-04-03 | The Government Of The United States Of America As Represented By The Secretary, Department Of Health And Human Services | GLP-1 exendin-4 peptide analogs and uses thereof |
GB0121709D0 (en) * | 2001-09-07 | 2001-10-31 | Imp College Innovations Ltd | Food inhibition agent |
CN100350968C (zh) * | 2001-09-24 | 2007-11-28 | 皇家创新有限公司 | 饮食行为的改进 |
EP2329839B1 (en) * | 2002-01-10 | 2015-09-16 | Imperial Innovations Limited | Modification of feeding behavior by GLP-1 and PYY |
US8058233B2 (en) * | 2002-01-10 | 2011-11-15 | Oregon Health And Science University | Modification of feeding behavior using PYY and GLP-1 |
AU2003231538A1 (en) * | 2002-05-17 | 2003-12-02 | Kyowa Hakko Kogyo Co., Ltd. | Method of searching substane having antidiabetic activity |
US7229966B2 (en) | 2002-12-17 | 2007-06-12 | Nastech Pharmaceutical Company Inc. | Compositions and methods for enhanced mucosal delivery of Y2 receptor-binding peptides and methods for treating and preventing obesity |
WO2004056314A2 (en) | 2002-12-17 | 2004-07-08 | Nastech Pharmaceutical Company Inc. | Compositions and methods for enhanced mucosal delivery of y2 receptor-binding peptides and methods for treating and preventing obesity |
US7166575B2 (en) * | 2002-12-17 | 2007-01-23 | Nastech Pharmaceutical Company Inc. | Compositions and methods for enhanced mucosal delivery of peptide YY and methods for treating and preventing obesity |
US7186692B2 (en) | 2002-12-17 | 2007-03-06 | Nastech Pharmaceutical Company Inc. | Compositions and methods for enhanced mucosal delivery and non-infused administration of Y2 receptor-binding peptides and methods for treating and preventing obesity |
GB0300571D0 (en) * | 2003-01-10 | 2003-02-12 | Imp College Innovations Ltd | Modification of feeding behaviour |
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EP2335716A3 (en) * | 2004-02-11 | 2011-10-19 | Amylin Pharmaceuticals Inc. | Pancreatic polypeptide family motifs and polypeptides comprising the same |
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AU2006235216C1 (en) * | 2005-04-13 | 2012-01-19 | Garvan Institute Of Medical Research | Modified animal lacking functional PYY gene, monoclonal antibodies that bind PYY isoforms and uses therefor |
CA2604423A1 (en) * | 2005-04-13 | 2006-10-19 | Garvan Institute Of Medical Research | Modified animal lacking functional pyy gene, monoclonal antibodies that bind pyy isoforms and uses therefor |
GB0511986D0 (en) * | 2005-06-13 | 2005-07-20 | Imp College Innovations Ltd | Novel compounds and their effects on feeding behaviour |
ATE532518T1 (de) | 2005-09-14 | 2011-11-15 | Takeda Pharmaceutical | Dipeptidyl-peptidase-hemmer zur behandlung von diabetes |
KR101368988B1 (ko) | 2005-09-16 | 2014-02-28 | 다케다 야쿠힌 고교 가부시키가이샤 | 디펩티딜 펩티다제 억제제 |
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US8759284B2 (en) | 2009-12-24 | 2014-06-24 | Rani Therapeutics, Llc | Therapeutic agent preparations for delivery into a lumen of the intestinal tract using a swallowable drug delivery device |
BR112013009635A2 (pt) | 2010-10-19 | 2016-07-12 | Elcelyx Therapeutics Inc | terapias à base de ligante de receptor quimiossensorial |
US9861683B2 (en) | 2010-12-23 | 2018-01-09 | Rani Therapeutics, Llc | Therapeutic agent preparations for delivery into a lumen of the intestinal tract using a swallowable drug delivery device |
US9402806B2 (en) | 2010-12-23 | 2016-08-02 | Rani Therapeutics, Llc | Therapeutic agent preparations for delivery into a lumen of the intestinal tract using a swallowable drug delivery device |
US9415004B2 (en) | 2010-12-23 | 2016-08-16 | Rani Therapeutics, Llc | Therapeutic agent preparations for delivery into a lumen of the intestinal tract using a swallowable drug delivery device |
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US8734429B2 (en) | 2010-12-23 | 2014-05-27 | Rani Therapeutics, Llc | Device, system and methods for the oral delivery of therapeutic compounds |
US9283179B2 (en) | 2010-12-23 | 2016-03-15 | Rani Therapeutics, Llc | GnRH preparations for delivery into a lumen of the intestinal tract using a swallowable drug delivery device |
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US8980822B2 (en) | 2010-12-23 | 2015-03-17 | Rani Therapeutics, Llc | Therapeutic agent preparations comprising pramlintide for delivery into a lumen of the intestinal tract using a swallowable drug delivery device |
US9617517B2 (en) | 2011-05-02 | 2017-04-11 | National University Corporation Kumamoto University | Small chemical compound which promotes induction of differentiation of stem cells into insulin-producing cells and method for inducing differentiation of stem cells into insulin-producing cells using said small chemical compound |
CN103981147B (zh) * | 2013-02-08 | 2017-11-10 | 中国科学院上海生命科学研究院 | 一种新的制备肝实质细胞的方法 |
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-
2000
- 2000-02-10 JP JP2000598171A patent/JP2003518914A/ja active Pending
- 2000-02-10 CA CA2360324A patent/CA2360324C/en not_active Expired - Fee Related
- 2000-02-10 US US09/499,526 patent/US7396809B1/en not_active Expired - Fee Related
- 2000-02-10 AT AT00913417T patent/ATE482717T1/de not_active IP Right Cessation
- 2000-02-10 AU AU34868/00A patent/AU779745C/en not_active Ceased
- 2000-02-10 EP EP00913417A patent/EP1189629B1/en not_active Expired - Lifetime
- 2000-02-10 DK DK00913417.2T patent/DK1189629T3/da active
- 2000-02-10 ES ES00913417T patent/ES2353728T3/es not_active Expired - Lifetime
- 2000-02-10 DE DE60045030T patent/DE60045030D1/de not_active Expired - Lifetime
- 2000-02-10 WO PCT/US2000/003391 patent/WO2000047219A2/en active Application Filing
- 2000-02-10 IL IL144703A patent/IL144703A/en not_active IP Right Cessation
-
2002
- 2002-09-24 HK HK02106949.7A patent/HK1045267A1/zh unknown
-
2005
- 2005-02-15 AU AU2005200685A patent/AU2005200685A1/en not_active Abandoned
-
2009
- 2009-07-21 IL IL199988A patent/IL199988A/en not_active IP Right Cessation
-
2010
- 2010-09-16 JP JP2010208097A patent/JP5766419B2/ja not_active Expired - Fee Related
-
2013
- 2013-06-19 JP JP2013128670A patent/JP2013188229A/ja active Pending
Also Published As
Publication number | Publication date |
---|---|
AU779745B2 (en) | 2005-02-10 |
IL199988A (en) | 2011-11-30 |
EP1189629B1 (en) | 2010-09-29 |
IL144703A (en) | 2010-04-15 |
JP2013188229A (ja) | 2013-09-26 |
WO2000047219A3 (en) | 2002-01-31 |
JP5766419B2 (ja) | 2015-08-19 |
AU779745C (en) | 2005-08-25 |
EP1189629A2 (en) | 2002-03-27 |
AU3486800A (en) | 2000-08-29 |
IL144703A0 (en) | 2002-06-30 |
CA2360324C (en) | 2016-03-29 |
CA2360324A1 (en) | 2000-08-17 |
DK1189629T3 (da) | 2011-01-03 |
US7396809B1 (en) | 2008-07-08 |
JP2011000128A (ja) | 2011-01-06 |
JP2003518914A (ja) | 2003-06-17 |
WO2000047219A2 (en) | 2000-08-17 |
DE60045030D1 (de) | 2010-11-11 |
AU2005200685A1 (en) | 2005-03-10 |
ATE482717T1 (de) | 2010-10-15 |
ES2353728T3 (es) | 2011-03-04 |
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