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GT199700104BA - PROCEDURES AND INTERMEDIATES TO PREPARE SUBSTITUTED CHROMANOL DERIVATIVES - Google Patents

PROCEDURES AND INTERMEDIATES TO PREPARE SUBSTITUTED CHROMANOL DERIVATIVES

Info

Publication number
GT199700104BA
GT199700104BA GT199700104BL GT199700104L GT199700104BA GT 199700104B A GT199700104B A GT 199700104BA GT 199700104B L GT199700104B L GT 199700104BL GT 199700104 L GT199700104 L GT 199700104L GT 199700104B A GT199700104B A GT 199700104BA
Authority
GT
Guatemala
Prior art keywords
intermediates
procedures
chromanol derivatives
substituted chromanol
prepare substituted
Prior art date
Application number
GT199700104BL
Other languages
Spanish (es)
Inventor
Anthony Piscopio
Joel M Hawkins
Stephane Caron
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed filed Critical
Publication of GT199700104BA publication Critical patent/GT199700104BA/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C33/00—Unsaturated compounds having hydroxy or O-metal groups bound to acyclic carbon atoms
    • C07C33/40—Halogenated unsaturated alcohols
    • C07C33/50—Halogenated unsaturated alcohols containing six-membered aromatic rings and other rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
    • C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D311/04—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
    • C07D311/22—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 4
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F5/00—Compounds containing elements of Groups 3 or 13 of the Periodic Table
    • C07F5/02—Boron compounds
    • C07F5/025—Boronic and borinic acid compounds

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyrane Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

ESTA INVENCION SE REFIERE A LA PREPARACION DE DERIVADOS DE CROMANOL SUSTITUIDOS Y A INTERMEDIOS UTILES EN DICHA PREPARACION. LOS DERIVADOS DE CROMANOL SUSTITUIDOS QUE SE PREPARAN DE ACUERDO CON LA PRESENTE INVENCION, INHIBEN LA ACCION DE LTB4. ESTOS COMPUESTOS TIENEN LA ESTRUCTURA QUIMICA(XIII), EN LA QUE R3,R4,R7, SON GRUPOS FUNCIONALES DESCRITOS EN EL EXPEDIENTE.THIS INVENTION REFERS TO THE PREPARATION OF SUBSTITUTED CHROMANOL DERIVATIVES AND TO USEFUL INTERMEDIATES IN SUCH PREPARATION. THE SUBSTITUTED CHROMANOL DERIVATIVES THAT ARE PREPARED IN ACCORDANCE WITH THE PRESENT INVENTION, INHIBIT THE ACTION OF LTB4. THESE COMPOUNDS HAVE THE CHEMICAL STRUCTURE (XIII), IN WHICH R3, R4, R7 ARE FUNCTIONAL GROUPS DESCRIBED IN THE FILE.

GT199700104BL 1996-09-16 1997-10-04 PROCEDURES AND INTERMEDIATES TO PREPARE SUBSTITUTED CHROMANOL DERIVATIVES GT199700104BA (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US2637296P 1996-09-16 1996-09-16

Publications (1)

Publication Number Publication Date
GT199700104BA true GT199700104BA (en) 1999-03-28

Family

ID=21831429

Family Applications (3)

Application Number Title Priority Date Filing Date
GT199700104A GT199700104A (en) 1996-09-16 1997-09-08 PROCEDURES AND INTERMEDIATES TO PREPARE SUBSTITUTED CHROMANOL DERIVATIVES.
GT199700104AK GT199700104AA (en) 1996-09-16 1997-10-04 PROCEDURES AND INTERMEDIATES TO PREPARE SUBSTITUTED CHROMANOL DERIVATIVES
GT199700104BL GT199700104BA (en) 1996-09-16 1997-10-04 PROCEDURES AND INTERMEDIATES TO PREPARE SUBSTITUTED CHROMANOL DERIVATIVES

Family Applications Before (2)

Application Number Title Priority Date Filing Date
GT199700104A GT199700104A (en) 1996-09-16 1997-09-08 PROCEDURES AND INTERMEDIATES TO PREPARE SUBSTITUTED CHROMANOL DERIVATIVES.
GT199700104AK GT199700104AA (en) 1996-09-16 1997-10-04 PROCEDURES AND INTERMEDIATES TO PREPARE SUBSTITUTED CHROMANOL DERIVATIVES

Country Status (39)

Country Link
US (4) US6096906A (en)
EP (1) EP0925292B1 (en)
JP (1) JP3117730B2 (en)
KR (1) KR100339164B1 (en)
CN (1) CN1108298C (en)
AP (1) AP726A (en)
AT (1) ATE249452T1 (en)
AU (1) AU713701B2 (en)
BG (1) BG63542B1 (en)
BR (1) BR9711482A (en)
CA (1) CA2265043C (en)
CO (1) CO4600635A1 (en)
DE (1) DE69724801T2 (en)
DK (1) DK0925292T3 (en)
DZ (1) DZ2308A1 (en)
EA (1) EA002204B1 (en)
ES (1) ES2206738T3 (en)
GT (3) GT199700104A (en)
HN (1) HN1997000127A (en)
HR (1) HRP970497B1 (en)
ID (1) ID19613A (en)
IL (1) IL128732A0 (en)
IS (1) IS4980A (en)
MA (1) MA24319A1 (en)
NO (1) NO991254L (en)
NZ (1) NZ334214A (en)
OA (1) OA10995A (en)
PA (1) PA8437901A1 (en)
PE (1) PE109798A1 (en)
PL (1) PL332351A1 (en)
PT (1) PT925292E (en)
SK (1) SK31399A3 (en)
TN (1) TNSN97155A1 (en)
TR (1) TR199900592T2 (en)
TW (1) TW449579B (en)
UA (1) UA58520C2 (en)
WO (1) WO1998011085A1 (en)
YU (1) YU13299A (en)
ZA (1) ZA978291B (en)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6436987B1 (en) * 2000-06-08 2002-08-20 Pfizer Inc. Crystalline forms of (3S-trans)-2-[3,4-dihydro-4-hydroxy-3-(phenylmethyl)-2H-1-benzopyran-7-yl]-4-(trifluoromethyl)-benzoic acid
WO2002060888A1 (en) * 2001-01-30 2002-08-08 Pfizer Products Inc. Processes for preparing chromanylbenzoic acids
AU4239302A (en) * 2001-06-28 2003-01-02 Pfizer Products Inc. Benzoic acid substituted benzopyrans for the treatment of atherosclerosis
JP2010534240A (en) * 2007-07-23 2010-11-04 ザ ボード オブ トラスティーズ オブ ザ ユニバーシティ オブ イリノイ Control system for boronic acid reactivity
US8338601B2 (en) * 2008-09-26 2012-12-25 Board Of Trustees Of The University Of Illinois Slow release of organoboronic acids in cross-coupling reactions
US20110213118A1 (en) * 2009-09-02 2011-09-01 E. I. Du Pont De Nemours And Company Polyaramid comprising fluorovinylether functionalized aromatic moieties
US20110218319A1 (en) * 2009-09-02 2011-09-08 E. I. Du Pont De Nemours And Company Polyaramid films comprising fluorovinylether functionalized aromatic moieties
BR112012004668A2 (en) 2009-09-02 2019-09-24 Du Pont "composition and process"
US8293928B2 (en) * 2009-09-02 2012-10-23 E I Du Pont De Nemours And Company Fluorinated 4-oxo-chroman-7-carboxylates
JP2013503942A (en) * 2009-09-02 2013-02-04 イー・アイ・デュポン・ドウ・ヌムール・アンド・カンパニー Polyesters containing fluorovinyl ether functionalized aromatic moieties
IN2012DN01776A (en) * 2009-09-02 2015-06-05 Du Pont
US8557980B2 (en) 2010-02-18 2013-10-15 The Board Of Trustees Of The University Of Illinois Methods for forming protected organoboronic acids
WO2016149126A1 (en) 2015-03-13 2016-09-22 The Board Of Trustees Of The Leland Stanford Junior University Ltb4 inhibition to prevent and treat human lymphedema

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9119920D0 (en) * 1991-09-18 1991-10-30 Glaxo Group Ltd Chemical compounds
MX9300312A (en) * 1992-01-23 1993-07-31 Pfizer BENZOPYRANIC AND RELATED ANTAGONISTS OF LTB.
HUT67929A (en) * 1992-01-23 1995-05-29 Pfizer Benzopyran and related ltb4 antagonists
CZ100095A3 (en) * 1992-10-21 1995-11-15 Pfizer Sulfonamide derivatives of hydroxy substituted alicyclic or heterocyclic compounds with condensed benzene nucleus and pharmaceutical preparations based thereon
AU4650493A (en) * 1992-10-21 1994-05-09 Pfizer Inc. (Enantiomeric cis)-3-(4,6-dihydroxychroman-3-YL-methyl)benzoic acids
RU2128655C1 (en) * 1994-10-13 1999-04-10 Пфайзер Инк. Benzopyrane and benzocondensed compounds, intermediate compounds, pharmaceutical composition and a method of inhibition
CN1166834A (en) * 1994-10-13 1997-12-03 美国辉瑞有限公司 Benzopyram and benzo-fused compounds, their preparation and their use as leukotriene B4'(LTB4) antagonists
US5539128A (en) * 1994-11-30 1996-07-23 Pfizer Inc. Processes and intermediates for preparing cis(+)3-[4,6-dihydroxy chroman-3-ylmethyl]-4-methoxyaniline

Also Published As

Publication number Publication date
CN1230954A (en) 1999-10-06
EP0925292A1 (en) 1999-06-30
MA24319A1 (en) 1998-04-01
NO991254D0 (en) 1999-03-15
CO4600635A1 (en) 1998-05-08
TNSN97155A1 (en) 2005-03-15
US6288242B1 (en) 2001-09-11
CA2265043C (en) 2003-01-14
DE69724801D1 (en) 2003-10-16
EP0925292B1 (en) 2003-09-10
PA8437901A1 (en) 2000-05-24
WO1998011085A1 (en) 1998-03-19
BG103231A (en) 1999-12-30
PL332351A1 (en) 1999-09-13
OA10995A (en) 2001-11-06
CN1108298C (en) 2003-05-14
DK0925292T3 (en) 2004-01-12
AU713701B2 (en) 1999-12-09
BR9711482A (en) 1999-08-24
KR20000036136A (en) 2000-06-26
BG63542B1 (en) 2002-04-30
ZA978291B (en) 1999-03-15
US6355825B1 (en) 2002-03-12
JP2000502726A (en) 2000-03-07
IL128732A0 (en) 2000-01-31
NZ334214A (en) 2000-09-29
JP3117730B2 (en) 2000-12-18
US6444826B1 (en) 2002-09-03
ATE249452T1 (en) 2003-09-15
GT199700104A (en) 1999-03-02
TW449579B (en) 2001-08-11
UA58520C2 (en) 2003-08-15
YU13299A (en) 2001-03-07
NO991254L (en) 1999-05-14
PE109798A1 (en) 1999-01-13
PT925292E (en) 2004-01-30
GT199700104AA (en) 1999-03-28
IS4980A (en) 1999-02-16
US20020042526A1 (en) 2002-04-11
DE69724801T2 (en) 2004-06-17
TR199900592T2 (en) 1999-06-21
ES2206738T3 (en) 2004-05-16
AU3781497A (en) 1998-04-02
KR100339164B1 (en) 2002-06-01
US20020099227A1 (en) 2002-07-25
HRP970497A2 (en) 1998-08-31
EA002204B1 (en) 2002-02-28
AP9701083A0 (en) 1997-10-31
ID19613A (en) 1998-07-23
HRP970497B1 (en) 2002-06-30
US6096906A (en) 2000-08-01
AP726A (en) 1999-01-29
HN1997000127A (en) 1997-12-20
EA199900204A1 (en) 1999-08-26
SK31399A3 (en) 2000-05-16
DZ2308A1 (en) 2002-12-28
CA2265043A1 (en) 1998-03-19

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