GR66057B - - Google Patents
Info
- Publication number
- GR66057B GR66057B GR55028A GR770155028A GR66057B GR 66057 B GR66057 B GR 66057B GR 55028 A GR55028 A GR 55028A GR 770155028 A GR770155028 A GR 770155028A GR 66057 B GR66057 B GR 66057B
- Authority
- GR
- Greece
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
- C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D307/93—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems condensed with a ring other than six-membered
- C07D307/935—Not further condensed cyclopenta [b] furans or hydrogenated cyclopenta [b] furans
- C07D307/937—Not further condensed cyclopenta [b] furans or hydrogenated cyclopenta [b] furans with hydrocarbon or substituted hydrocarbon radicals directly attached in position 2, e.g. prostacyclins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C405/00—Compounds containing a five-membered ring having two side-chains in ortho position to each other, and having oxygen atoms directly attached to the ring in ortho position to one of the side-chains, one side-chain containing, not directly attached to the ring, a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, and the other side-chain having oxygen atoms attached in gamma-position to the ring, e.g. prostaglandins ; Analogues or derivatives thereof
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Furan Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IT3104176A IT1072541B (it) | 1976-12-31 | 1976-12-31 | 6(9)-ossido-prostenoici acidi |
| IT1928377A IT1079103B (it) | 1977-01-14 | 1977-01-14 | Derivati del 9-ossido-alo-prostanoico acido |
| IT2117177A IT1085878B (it) | 1977-03-14 | 1977-03-14 | Bicilicli ossiranici 15-cheto-prostenoici acidi |
| IT2141277A IT1075678B (it) | 1977-03-21 | 1977-03-21 | 15-idrossi-bicicliche prostaglandine |
| IT2186377A IT1115636B (it) | 1977-03-31 | 1977-03-31 | 13,14-deidro-bicicliche prostaglandine |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GR66057B true GR66057B (el) | 1981-01-14 |
Family
ID=27517783
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GR55028A GR66057B (el) | 1976-12-31 | 1977-12-22 |
Country Status (19)
| Country | Link |
|---|---|
| US (9) | US4297368A (el) |
| JP (1) | JPS5384959A (el) |
| BE (1) | BE862514A (el) |
| CH (1) | CH636096A5 (el) |
| DE (1) | DE2757919A1 (el) |
| DK (1) | DK586077A (el) |
| FI (1) | FI71138C (el) |
| FR (1) | FR2376147A1 (el) |
| GB (1) | GB1599280A (el) |
| GR (1) | GR66057B (el) |
| HU (1) | HU182725B (el) |
| IL (1) | IL53630A0 (el) |
| KE (1) | KE3196A (el) |
| MY (1) | MY8200265A (el) |
| NL (1) | NL7714613A (el) |
| NO (1) | NO153689C (el) |
| NZ (1) | NZ185986A (el) |
| SE (1) | SE437268B (el) |
| YU (1) | YU316677A (el) |
Families Citing this family (28)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IT1053781B (it) * | 1974-09-25 | 1981-10-10 | Erba C S P A Ora Farmitalia | Omega nor cicloalcil 13.14 deidro prostaglandine |
| US4178367A (en) * | 1977-02-21 | 1979-12-11 | Ono Pharmaceutical Co. Ltd. | Prostaglandin I2 analogues |
| HU182583B (en) * | 1977-03-01 | 1984-02-28 | Chinoin Gyogyszer Es Vegyeszet | Process for preparing prostacyclin and analogues thereof |
| AU524786B2 (en) * | 1977-03-07 | 1982-10-07 | The Upjohn Company | Prostacyclins |
| IT1088966B (it) * | 1977-11-15 | 1985-06-10 | Erba Carlo Spa | 13,14-dideidro-prostaglandine |
| US4206127A (en) * | 1977-11-23 | 1980-06-03 | Miles Laboratories, Inc. | 5,6-Dihydro analogues of prostaglandin I2 |
| BE871209R (fr) * | 1977-12-05 | 1979-04-12 | Upjohn Co | Analogues de 5,6-dihydro-prostacycline et leur preparation |
| IL58384A0 (en) | 1978-10-14 | 1980-01-31 | Beecham Group Ltd | 12-aza analogues of prostcyclin their preparation and pharmaceutical composition containing them |
| DE2947526A1 (de) * | 1978-11-29 | 1980-06-12 | Ono Pharmaceutical Co | Prostacyclin-analoge |
| US4237060A (en) | 1979-03-23 | 1980-12-02 | Hoffmann-La Roche Inc. | Prostacyclin analogs |
| US4235924A (en) | 1979-06-07 | 1980-11-25 | American Cyanamid Company | Prostacyclin analogs of the 1 series and related analogs wherein the carboxylic acid function has been replaced |
| US4321203A (en) * | 1979-07-05 | 1982-03-23 | The Upjohn Company | 19-Hydroxy-7a-homo-PGI1 compounds |
| US4301079A (en) * | 1979-07-05 | 1981-11-17 | The Upjohn Company | 19-Hydroxy-19-methyl-PGI1 compounds |
| US4273718A (en) * | 1979-07-05 | 1981-06-16 | The Upjohn Company | 2-Decarboxy-2-hydroxymethyl-9-deoxy-6ε,9αepoxy-16,16-difluoro-19-hydroxy-PGF1 |
| US4328156A (en) * | 1979-07-05 | 1982-05-04 | The Upjohn Company | 19-Hydroxy-19-methyl-7α-homo-PGI1 compounds |
| US4474966A (en) * | 1980-03-03 | 1984-10-02 | The Upjohn Company | 19-Hydroxy-7a-homo-PGI1 and 19-hydroxy-19-methyl-7a-homo-PGI1 compounds |
| DE3035713A1 (de) * | 1980-09-22 | 1982-04-29 | F. Hoffmann-La Roche & Co. AG, 4002 Basel | Prostacycline |
| EP0059307A1 (de) | 1981-02-26 | 1982-09-08 | Grünenthal GmbH | Verfahren zur Herstellung von 2-Oxabicyclo(3.3.0)octanderivaten und danach erhältliche Produkte |
| CH656877A5 (de) * | 1981-11-27 | 1986-07-31 | Erba Farmitalia | Optisch aktive oder racemische prostaglandinderivate. |
| EP0108451A3 (en) * | 1982-11-05 | 1985-04-10 | The Procter & Gamble Company | Novel prostaglandin analogues |
| US4576962A (en) * | 1983-10-19 | 1986-03-18 | The Procter & Gamble Company | Prostaglandin analogues |
| US5153174A (en) * | 1989-10-30 | 1992-10-06 | Union Carbide Chemicals & Plastics Inc. | Polymer mixtures useful in skin care |
| WO1999012899A1 (en) * | 1997-09-09 | 1999-03-18 | The Procter & Gamble Company | A process for making prostaglandin f analogs |
| JP4767842B2 (ja) * | 2003-04-01 | 2011-09-07 | セラヴァンス， インコーポレーテッド | β２アドレナリン作用性レセプターアゴニスト活性およびムスカリン性レセプターアンタゴニスト活性を有するジアリールメチル化合物および関連化合物 |
| JP5652397B2 (ja) | 2009-07-28 | 2015-01-14 | 小野薬品工業株式会社 | 二環式化合物およびその医薬用途 |
| ES2581852T3 (es) | 2011-01-27 | 2016-09-07 | Ono Pharmaceutical Co., Ltd. | Compuesto bicíclico y uso del mismo para fines médicos |
| WO2012102357A1 (ja) | 2011-01-27 | 2012-08-02 | 小野薬品工業株式会社 | 二環式化合物およびその医薬用途 |
| US10899729B2 (en) | 2016-06-30 | 2021-01-26 | Ono Pharmaceutical Co.. Ltd. | Method for producing bicyclic compound |
Family Cites Families (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IL51189A (en) * | 1976-02-04 | 1985-08-30 | Upjohn Co | Prostaglandin analogs |
| DE2720998A1 (de) * | 1976-05-11 | 1977-11-24 | Wellcome Found | Cyclische aether, verfahren zu ihrer herstellung und sie enthaltende pharmazeutische praeparate |
| GB1583961A (en) * | 1976-05-11 | 1981-02-04 | Wellcome Found | Prostacyclin and derivatives thereof |
| US4125712A (en) * | 1976-06-01 | 1978-11-14 | The Upjohn Company | Certain 5,6-dihydro-prostacyclin analogs |
| MX4813E (es) * | 1976-06-01 | 1982-10-19 | Upjohn Co | Procedimiento para preparar analogos de prostaglandinas |
| US4123441A (en) * | 1976-09-22 | 1978-10-31 | The Upjohn Company | Enlarged-hetero-ring prostacyclin analogs |
| GB1595056A (en) * | 1976-10-12 | 1981-08-05 | Wellcome Found | Pharmaceutical combination |
| AU511711B2 (en) * | 1976-12-30 | 1980-09-04 | Upjohn Company, The | 6-Oxo and 5, 6-Dihalo prostaglandin analogues |
| HU182583B (en) | 1977-03-01 | 1984-02-28 | Chinoin Gyogyszer Es Vegyeszet | Process for preparing prostacyclin and analogues thereof |
| AU524786B2 (en) * | 1977-03-07 | 1982-10-07 | The Upjohn Company | Prostacyclins |
| GB2002363B (en) * | 1977-08-03 | 1982-03-24 | Upjohn Co | Prostacyclin analogues |
| US4206127A (en) * | 1977-11-23 | 1980-06-03 | Miles Laboratories, Inc. | 5,6-Dihydro analogues of prostaglandin I2 |
-
1977
- 1977-12-13 FI FI773757A patent/FI71138C/fi not_active IP Right Cessation
- 1977-12-15 NZ NZ185986A patent/NZ185986A/xx unknown
- 1977-12-18 IL IL53630A patent/IL53630A0/xx unknown
- 1977-12-21 GB GB53226/77A patent/GB1599280A/en not_active Expired
- 1977-12-22 GR GR55028A patent/GR66057B/el unknown
- 1977-12-24 DE DE19772757919 patent/DE2757919A1/de not_active Withdrawn
- 1977-12-28 JP JP15758977A patent/JPS5384959A/ja active Pending
- 1977-12-29 DK DK586077A patent/DK586077A/da not_active Application Discontinuation
- 1977-12-30 NL NL7714613A patent/NL7714613A/xx not_active Application Discontinuation
- 1977-12-30 YU YU03166/77A patent/YU316677A/xx unknown
- 1977-12-30 BE BE183997A patent/BE862514A/xx not_active IP Right Cessation
- 1977-12-30 SE SE7714948A patent/SE437268B/sv unknown
- 1977-12-30 NO NO774524A patent/NO153689C/no unknown
- 1977-12-30 HU HU77EA181A patent/HU182725B/hu unknown
- 1977-12-30 FR FR7739879A patent/FR2376147A1/fr active Granted
-
1978
- 1978-01-03 CH CH4978A patent/CH636096A5/de not_active IP Right Cessation
- 1978-06-29 US US05/920,166 patent/US4297368A/en not_active Expired - Lifetime
- 1978-07-28 US US05/928,809 patent/US4328240A/en not_active Expired - Lifetime
- 1978-12-01 US US05/965,267 patent/US4277491A/en not_active Expired - Lifetime
-
1979
- 1979-02-26 US US05/015,148 patent/US4230721A/en not_active Expired - Lifetime
- 1979-04-13 US US06/029,925 patent/US4303670A/en not_active Expired - Lifetime
- 1979-06-18 US US06/049,326 patent/US4262016A/en not_active Expired - Lifetime
- 1979-06-18 US US06/049,118 patent/US4254137A/en not_active Expired - Lifetime
- 1979-11-01 US US06/090,305 patent/US4250188A/en not_active Expired - Lifetime
- 1979-11-30 US US06/098,963 patent/US4271184A/en not_active Expired - Lifetime
-
1982
- 1982-03-17 KE KE3196A patent/KE3196A/xx unknown
- 1982-12-30 MY MY265/82A patent/MY8200265A/xx unknown
Also Published As
| Publication number | Publication date |
|---|---|
| US4250188A (en) | 1981-02-10 |
| NO153689C (no) | 1986-05-07 |
| BE862514A (fr) | 1978-04-14 |
| US4254137A (en) | 1981-03-03 |
| NL7714613A (nl) | 1978-07-04 |
| US4262016A (en) | 1981-04-14 |
| MY8200265A (en) | 1982-12-31 |
| GB1599280A (en) | 1981-09-30 |
| US4297368A (en) | 1981-10-27 |
| JPS5384959A (en) | 1978-07-26 |
| SE437268B (sv) | 1985-02-18 |
| FR2376147A1 (fr) | 1978-07-28 |
| US4303670A (en) | 1981-12-01 |
| HU182725B (en) | 1984-03-28 |
| US4328240A (en) | 1982-05-04 |
| US4230721A (en) | 1980-10-28 |
| NO774524L (no) | 1978-07-03 |
| CH636096A5 (de) | 1983-05-13 |
| US4271184A (en) | 1981-06-02 |
| KE3196A (en) | 1982-04-02 |
| NZ185986A (en) | 1979-12-11 |
| FR2376147B1 (el) | 1982-01-08 |
| FI773757A (fi) | 1978-07-01 |
| US4277491A (en) | 1981-07-07 |
| SE7714948L (sv) | 1978-07-01 |
| NO153689B (no) | 1986-01-27 |
| DE2757919A1 (de) | 1978-07-13 |
| IL53630A0 (en) | 1978-03-10 |
| FI71138B (fi) | 1986-08-14 |
| YU316677A (en) | 1984-02-29 |
| DK586077A (da) | 1978-07-01 |
| FI71138C (fi) | 1986-11-24 |