Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB723254A
Inventor
Alfred Aaron Levi
Robert Rothes Goodall
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Imperial Chemical Industries Ltd
Original Assignee
Imperial Chemical Industries Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Imperial Chemical Industries LtdfiledCriticalImperial Chemical Industries Ltd
Priority to GB723254ApriorityCriticalpatent/GB763482A/en
Publication of GB763482ApublicationCriticalpatent/GB763482A/en
The process of the parent Specification for the isolation of fumagillin from fumagillin-containing biologically manufactured crude solids wherein the crude solids are distributed between an aqueous solution of pH higher than 7 and lower than 12, and a suitable organic solvent (defined), is improved by treating the permeated broth from which the fumagillin containing crude solids are to be obtained, prior to its extraction with said organic solvent, with a water-soluble barium salt, e.g. barium chloride. The water-soluble barium salt is added to the fermentation broth, preferably after filtration thereof, either as the solid, or in the form of an aqueous solution preferably concentrated.
GB723254A1954-03-121954-03-12Improvements in or relating to the manufacture of fumagillin
ExpiredGB763482A
(en)