GB2213480B - Dioxazocine derivatives, their preparation and compositions containing them - Google Patents

Dioxazocine derivatives, their preparation and compositions containing them

Info

Publication number: GB2213480B
Authority: GB; United Kingdom
Prior art keywords: preparation; compositions containing; dioxazocine; derivatives; dioxazocine derivatives
Prior art date: 1987-12-31
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.): Expired - Lifetime

Application number

GB8830416A

Other languages

English (en)

Other versions

GB8830416D0 (en

GB2213480A (en

Inventor

Istvan Gacsalyi

Laszlo Rozsa

Lujza Petocz

Eniko Szirt

Marton Fekete

Maria Szecsey

Gabor Gigler

Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)

Egyt Gyogyszervegyeszeti Gyar

Egis Pharmaceuticals PLC

Original Assignee

Egyt Gyogyszervegyeszeti Gyar

Egis Pharmaceuticals PLC

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1987-12-31

Filing date

1988-12-30

Publication date

1991-06-26

1988-12-30 Application filed by Egyt Gyogyszervegyeszeti Gyar, Egis Pharmaceuticals PLC filed Critical Egyt Gyogyszervegyeszeti Gyar

1989-03-01 Publication of GB8830416D0 publication Critical patent/GB8830416D0/en

1989-08-16 Publication of GB2213480A publication Critical patent/GB2213480A/en

1991-06-26 Application granted granted Critical

1991-06-26 Publication of GB2213480B publication Critical patent/GB2213480B/en

2008-12-30 Anticipated expiration legal-status Critical

Status Expired - Lifetime legal-status Critical Current

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D273/00—Heterocyclic compounds containing rings having nitrogen and oxygen atoms as the only ring hetero atoms, not provided for by groups C07D261/00 - C07D271/00
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D273/00—Heterocyclic compounds containing rings having nitrogen and oxygen atoms as the only ring hetero atoms, not provided for by groups C07D261/00 - C07D271/00
- C07D273/01—Heterocyclic compounds containing rings having nitrogen and oxygen atoms as the only ring hetero atoms, not provided for by groups C07D261/00 - C07D271/00 having one nitrogen atom
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P21/00—Drugs for disorders of the muscular or neuromuscular system
- A61P21/02—Muscle relaxants, e.g. for tetanus or cramps
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P23/00—Anaesthetics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P23/00—Anaesthetics
- A61P23/02—Local anaesthetics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/08—Antiepileptics; Anticonvulsants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/20—Hypnotics; Sedatives
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/22—Anxiolytics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/26—Psychostimulants, e.g. nicotine, cocaine
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/06—Antiarrhythmics

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
General Health & Medical Sciences (AREA)
Animal Behavior & Ethology (AREA)
Veterinary Medicine (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Public Health (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
Bioinformatics & Cheminformatics (AREA)
Engineering & Computer Science (AREA)
Neurology (AREA)
Neurosurgery (AREA)
Biomedical Technology (AREA)
Anesthesiology (AREA)
Pain & Pain Management (AREA)
Psychiatry (AREA)
Cardiology (AREA)
Heart & Thoracic Surgery (AREA)
Orthopedic Medicine & Surgery (AREA)
Physical Education & Sports Medicine (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Plural Heterocyclic Compounds (AREA)
Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)

GB8830416A 1987-12-31 1988-12-30 Dioxazocine derivatives, their preparation and compositions containing them Expired - Lifetime GB2213480B (en)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
HU876170A HU201318B (en)	1987-12-31	1987-12-31	Process for producing dioxazoline derivatives and pharmaceutical compositions comprising same

Publications (3)

Publication Number	Publication Date
GB8830416D0 GB8830416D0 (en)	1989-03-01
GB2213480A GB2213480A (en)	1989-08-16
GB2213480B true GB2213480B (en)	1991-06-26

Family

ID=10971300

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
GB8830416A Expired - Lifetime GB2213480B (en)	1987-12-31	1988-12-30	Dioxazocine derivatives, their preparation and compositions containing them

Country Status (22)

Country	Link
US (1)	US4965259A (da)
JP (1)	JPH01213273A (da)
KR (1)	KR890009896A (da)
CN (1)	CN1034926A (da)
AU (1)	AU610678B2 (da)
BE (1)	BE1002696A3 (da)
CH (1)	CH677669A5 (da)
CS (1)	CS272247B2 (da)
DE (1)	DE3844394A1 (da)
DK (1)	DK733688A (da)
ES (1)	ES2010855A6 (da)
FI (1)	FI886065A (da)
FR (1)	FR2625503A1 (da)
GB (1)	GB2213480B (da)
GR (1)	GR1000098B (da)
HU (1)	HU201318B (da)
IT (1)	IT1227920B (da)
NL (1)	NL8803218A (da)
PL (1)	PL154357B1 (da)
SE (1)	SE8804696L (da)
SU (1)	SU1641190A3 (da)
YU (1)	YU240088A (da)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
HU198194B (en) *	1986-12-30	1989-08-28	Egyt Gyogyszervegyeszeti Gyar	Process for production of new derivatives of dioxazocin and medical compositions containing them
DK0423870T3 (da) *	1989-10-20	1993-10-11	Akzo Nobel Nv	Dibenzodioxazecin- dibenzodioxaazacycloundecinderivater
WO1997011071A1 (en) *	1995-09-19	1997-03-27	Novo Nordisk A/S	Novel heterocyclic compounds

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
NL108827C (da) *	1956-04-09
US3258459A (en) *	1962-08-30	1966-06-28	Squibb & Sons Inc	Method for the preparation of n-monosubstituted-secondary aminoalkyl derivatives of polycyclic compounds
US3803143A (en) *	1969-09-08	1974-04-09	Eisai Co Ltd	6-amino alkylene 6,7-dihydro-5h-dibenzo (b,g),(1,5)thiazocines
GB1464431A (en) *	1974-03-25	1977-02-16	Roche Products Ltd	Indolobenzazepine derivatives and a process for the manufacture thereof
HU174126B (hu) *	1977-08-02	1979-11-28	Egyt Gyogyszervegyeszeti Gyar	Sposob poluchenija novykh proizvodnykh dibenzo-kvadratnaja skobka-d,g-kvadratnaja skobka zakryta-kvadratnaja skobka-1,3,6-kvadratnaja skobka zakryta-dioksazocina
HU195491B (en) *	1985-12-20	1988-05-30	Egyt Gyogyszervegyeszeti Gyar	Process for production of optically active 2-chlor-12-/3-/dimethil-amin/-2-methil-prophil/-12h-dibenzol /d,g/ /1,3,6/-diaxazocine and medical compositions containing such compounds
HU198194B (en) *	1986-12-30	1989-08-28	Egyt Gyogyszervegyeszeti Gyar	Process for production of new derivatives of dioxazocin and medical compositions containing them

1987
- 1987-12-31 HU HU876170A patent/HU201318B/hu not_active IP Right Cessation
1988
- 1988-12-28 JP JP63329542A patent/JPH01213273A/ja active Pending
- 1988-12-28 CH CH4833/88A patent/CH677669A5/de not_active IP Right Cessation
- 1988-12-29 SE SE8804696A patent/SE8804696L/xx not_active Application Discontinuation
- 1988-12-29 FR FR8817385A patent/FR2625503A1/fr not_active Withdrawn
- 1988-12-30 NL NL8803218A patent/NL8803218A/nl not_active Application Discontinuation
- 1988-12-30 CN CN88108995A patent/CN1034926A/zh active Pending
- 1988-12-30 GR GR880100870A patent/GR1000098B/el unknown
- 1988-12-30 YU YU02400/88A patent/YU240088A/xx unknown
- 1988-12-30 DE DE3844394A patent/DE3844394A1/de not_active Withdrawn
- 1988-12-30 US US07/292,450 patent/US4965259A/en not_active Expired - Fee Related
- 1988-12-30 DK DK733688A patent/DK733688A/da not_active Application Discontinuation
- 1988-12-30 IT IT8823183A patent/IT1227920B/it active
- 1988-12-30 GB GB8830416A patent/GB2213480B/en not_active Expired - Lifetime
- 1988-12-30 ES ES8900367A patent/ES2010855A6/es not_active Expired
- 1988-12-30 BE BE8801449A patent/BE1002696A3/fr not_active IP Right Cessation
- 1988-12-30 SU SU884613167A patent/SU1641190A3/ru active
- 1988-12-30 CS CS889102A patent/CS272247B2/cs unknown
- 1988-12-30 PL PL1988276891A patent/PL154357B1/pl unknown
- 1988-12-30 KR KR1019880018006A patent/KR890009896A/ko not_active Application Discontinuation
- 1988-12-30 AU AU27637/88A patent/AU610678B2/en not_active Ceased
- 1988-12-30 FI FI886065A patent/FI886065A/fi not_active Application Discontinuation

Also Published As

Publication number	Publication date
FR2625503A1 (fr)	1989-07-07
PL276891A1 (en)	1989-12-27
PL154357B1 (en)	1991-08-30
CH677669A5 (da)	1991-06-14
IT1227920B (it)	1991-05-14
AU610678B2 (en)	1991-05-23
GB8830416D0 (en)	1989-03-01
ES2010855A6 (es)	1989-12-01
GR1000098B (el)	1991-03-15
SE8804696D0 (sv)	1988-12-29
HUT50144A (en)	1989-12-28
IT8823183A0 (it)	1988-12-30
HU201318B (en)	1990-10-28
CS272247B2 (en)	1991-01-15
DE3844394A1 (de)	1989-07-13
FI886065A (fi)	1989-07-01
SU1641190A3 (ru)	1991-04-07
GB2213480A (en)	1989-08-16
AU2763788A (en)	1989-07-06
US4965259A (en)	1990-10-23
NL8803218A (nl)	1989-07-17
YU240088A (en)	1990-02-28
CN1034926A (zh)	1989-08-23
BE1002696A3 (fr)	1991-05-07
DK733688A (da)	1989-07-01
CS910288A2 (en)	1990-03-14
JPH01213273A (ja)	1989-08-28
KR890009896A (ko)	1989-08-04
DK733688D0 (da)	1988-12-30
SE8804696L (sv)	1989-07-01

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Legal Events

Date	Code	Title	Description
1993-08-25	PCNP	Patent ceased through non-payment of renewal fee	Effective date: 19921230