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FR2553416B3 - Derive de pyrrolo-quinoline, sa preparation et son application en therapeutique - Google Patents

Derive de pyrrolo-quinoline, sa preparation et son application en therapeutique

Info

Publication number
FR2553416B3
FR2553416B3 FR8316474A FR8316474A FR2553416B3 FR 2553416 B3 FR2553416 B3 FR 2553416B3 FR 8316474 A FR8316474 A FR 8316474A FR 8316474 A FR8316474 A FR 8316474A FR 2553416 B3 FR2553416 B3 FR 2553416B3
Authority
FR
France
Prior art keywords
pyrrolo
therapeutics
preparation
application
quinoline derivative
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
FR8316474A
Other languages
English (en)
Other versions
FR2553416A1 (fr
Inventor
Dennis Bigg
Claude Morel
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Synthelabo SA
Original Assignee
Synthelabo SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Synthelabo SA filed Critical Synthelabo SA
Priority to FR8316474A priority Critical patent/FR2553416B3/fr
Priority to EP84402019A priority patent/EP0139584B1/fr
Priority to AT84402019T priority patent/ATE34392T1/de
Priority to DE8484402019T priority patent/DE3471308D1/de
Priority to MX203064A priority patent/MX157033A/es
Priority to ES536786A priority patent/ES536786A0/es
Priority to CA000465553A priority patent/CA1219261A/fr
Priority to HU843864A priority patent/HUT36476A/hu
Priority to PT79365A priority patent/PT79365B/fr
Priority to ZA848069A priority patent/ZA848069B/xx
Priority to US06/661,483 priority patent/US4567177A/en
Priority to GR80671A priority patent/GR80671B/el
Priority to AU34270/84A priority patent/AU564510B2/en
Priority to NO844118A priority patent/NO161738C/no
Priority to DK493784A priority patent/DK493784A/da
Priority to IL73259A priority patent/IL73259A/xx
Priority to JP59218168A priority patent/JPS60104087A/ja
Priority to FI844069A priority patent/FI76800C/fi
Priority to KR1019840006390A priority patent/KR850002975A/ko
Priority to NZ209912A priority patent/NZ209912A/en
Priority to AR29827384A priority patent/AR240700A1/es
Publication of FR2553416A1 publication Critical patent/FR2553416A1/fr
Application granted granted Critical
Publication of FR2553416B3 publication Critical patent/FR2553416B3/fr
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/06—Peri-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/26—Psychostimulants, e.g. nicotine, cocaine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/04—Anorexiants; Antiobesity agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/02—Non-specific cardiovascular stimulants, e.g. drugs for syncope, antihypotensives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D223/00—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom
    • C07D223/02—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom not condensed with other rings
    • C07D223/04—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom not condensed with other rings with only hydrogen atoms, halogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/06—Peri-condensed systems

Landscapes

  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Cardiology (AREA)
  • Psychiatry (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Pain & Pain Management (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Child & Adolescent Psychology (AREA)
  • Pulmonology (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
FR8316474A 1983-10-17 1983-10-17 Derive de pyrrolo-quinoline, sa preparation et son application en therapeutique Expired FR2553416B3 (fr)

Priority Applications (21)

Application Number Priority Date Filing Date Title
FR8316474A FR2553416B3 (fr) 1983-10-17 1983-10-17 Derive de pyrrolo-quinoline, sa preparation et son application en therapeutique
AT84402019T ATE34392T1 (de) 1983-10-17 1984-10-08 Imidazolinderivate, ihre herstellung und therapeutische verwendung.
DE8484402019T DE3471308D1 (en) 1983-10-17 1984-10-08 Imidazoline derivatives, their preparation and therapeutical use
EP84402019A EP0139584B1 (fr) 1983-10-17 1984-10-08 Dérivés d'imidazoline, leur préparation et leur application en thérapeutique
IL73259A IL73259A (en) 1983-10-17 1984-10-16 2-(2-imidazolin-2-yl)pyrrolo(3,2,1-ij)quinoline(and azepino(3,2,1-hi)indole)derivatives and pharmaceutical compositions containing them
CA000465553A CA1219261A (fr) 1983-10-17 1984-10-16 Derives d'imidazoline, leur preparation, et produits pharmaceutiques qui les renferment
HU843864A HUT36476A (en) 1983-10-17 1984-10-16 Process for producing imidazoline derivatives and pharmaceutical compositions containing them
PT79365A PT79365B (fr) 1983-10-17 1984-10-16 Procede de preparation de derives d'imidazoline et de compositions pharmaceutiques les contenant
ZA848069A ZA848069B (en) 1983-10-17 1984-10-16 Imidazoline derivatives,their preparation and pharmaceutical compositions containing them
US06/661,483 US4567177A (en) 1983-10-17 1984-10-16 Imidazoline derivatives as α2 -antagonists
MX203064A MX157033A (es) 1983-10-17 1984-10-16 Procedimiento para preparar derivados de pirrolo quinoleina
AU34270/84A AU564510B2 (en) 1983-10-17 1984-10-16 (4,5-dihydro-1h-imidazo-z-yl)-1,2,4,5,6,7-hexa hydroazepino (3,2,1-hi) indole derivatives
NO844118A NO161738C (no) 1983-10-17 1984-10-16 Analogifremgangsm te for fremstilling av terapeutisk aktive imidazolinderivater.
DK493784A DK493784A (da) 1983-10-17 1984-10-16 Imidazolinderivater og fremgangsmaade til fremstilling deraf samt laegemiddel indeholdende saadanne forbindelser
ES536786A ES536786A0 (es) 1983-10-17 1984-10-16 Procedimiento para preparar derivados de imidazolina
JP59218168A JPS60104087A (ja) 1983-10-17 1984-10-16 イミダゾリン誘導体
FI844069A FI76800C (fi) 1983-10-17 1984-10-16 Foerfarande foer framstaellning av 2-(2-imidazolyl)pyrrolo/3,2-ij/kinoliner och 2-(2-imidazolyl)azepino /3,2,1-hi/indoler, vilka aer antagonister mot 2-adrenergiska receptorer.
KR1019840006390A KR850002975A (ko) 1983-10-17 1984-10-16 이미다졸린 유도체의 제조방법
GR80671A GR80671B (en) 1983-10-17 1984-10-16 Process for the preparation of imidazoline derivatives
NZ209912A NZ209912A (en) 1983-10-17 1984-10-17 Imidazoline derivatives and pharmaceutical compositions
AR29827384A AR240700A1 (es) 1983-10-17 1984-10-17 Procedimiento para preparar derivados de (imidazolil-2)-2-pirrol3,2,1-ij quinolina o de (imidazolil-2)-2-azepin3,2,1-hi-indol

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR8316474A FR2553416B3 (fr) 1983-10-17 1983-10-17 Derive de pyrrolo-quinoline, sa preparation et son application en therapeutique

Publications (2)

Publication Number Publication Date
FR2553416A1 FR2553416A1 (fr) 1985-04-19
FR2553416B3 true FR2553416B3 (fr) 1986-05-30

Family

ID=9293211

Family Applications (1)

Application Number Title Priority Date Filing Date
FR8316474A Expired FR2553416B3 (fr) 1983-10-17 1983-10-17 Derive de pyrrolo-quinoline, sa preparation et son application en therapeutique

Country Status (3)

Country Link
JP (1) JPS60104087A (fr)
FR (1) FR2553416B3 (fr)
ZA (1) ZA848069B (fr)

Also Published As

Publication number Publication date
ZA848069B (en) 1985-06-26
JPS60104087A (ja) 1985-06-08
FR2553416A1 (fr) 1985-04-19

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