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FR2437833A1 - Treatment of fungal esp. vaginal infections - by administering a chelating agent for zinc ions - Google Patents

Treatment of fungal esp. vaginal infections - by administering a chelating agent for zinc ions

Info

Publication number
FR2437833A1
FR2437833A1 FR7828253A FR7828253A FR2437833A1 FR 2437833 A1 FR2437833 A1 FR 2437833A1 FR 7828253 A FR7828253 A FR 7828253A FR 7828253 A FR7828253 A FR 7828253A FR 2437833 A1 FR2437833 A1 FR 2437833A1
Authority
FR
France
Prior art keywords
esp
administering
vaginal infections
fungal
treatment
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
FR7828253A
Other languages
French (fr)
Other versions
FR2437833B1 (en
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Individual
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Priority to FR7828253A priority Critical patent/FR2437833A1/en
Publication of FR2437833A1 publication Critical patent/FR2437833A1/en
Application granted granted Critical
Publication of FR2437833B1 publication Critical patent/FR2437833B1/fr
Granted legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0034—Urogenital system, e.g. vagina, uterus, cervix, penis, scrotum, urethra, bladder; Personal lubricants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Reproductive Health (AREA)
  • Gynecology & Obstetrics (AREA)
  • Urology & Nephrology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

A process is claimed for destroying fungi which require Zn for the secondary metabolic process necessary for their growth. The process comprises administering to infected mammals (esp. humans) an effective amt. of a cpd. (I) capable of chelating Zn ions at a concn. of >=3.5% and a pH of 4.5-10. A typical cpd. (I) is EDTA or its Na2Ca salt. The process is esp. useful for treating vaginal infections due to Candida albicans. Other susceptible fungi include Crytococcus neoformans, torulopsis spp, Candida tropicalis and Penicillium spp.
FR7828253A 1978-10-03 1978-10-03 Treatment of fungal esp. vaginal infections - by administering a chelating agent for zinc ions Granted FR2437833A1 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
FR7828253A FR2437833A1 (en) 1978-10-03 1978-10-03 Treatment of fungal esp. vaginal infections - by administering a chelating agent for zinc ions

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR7828253A FR2437833A1 (en) 1978-10-03 1978-10-03 Treatment of fungal esp. vaginal infections - by administering a chelating agent for zinc ions

Publications (2)

Publication Number Publication Date
FR2437833A1 true FR2437833A1 (en) 1980-04-30
FR2437833B1 FR2437833B1 (en) 1981-07-31

Family

ID=9213279

Family Applications (1)

Application Number Title Priority Date Filing Date
FR7828253A Granted FR2437833A1 (en) 1978-10-03 1978-10-03 Treatment of fungal esp. vaginal infections - by administering a chelating agent for zinc ions

Country Status (1)

Country Link
FR (1) FR2437833A1 (en)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4399149A (en) * 1981-01-23 1983-08-16 Shell Oil Company Fungicides
EP2227213A1 (en) * 2007-11-30 2010-09-15 Toltec Pharmaceuticals, Llc Compositions and methods for treating vaginal infections and pathogenic vaginal biofilms

Cited By (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4399149A (en) * 1981-01-23 1983-08-16 Shell Oil Company Fungicides
EP2227213A1 (en) * 2007-11-30 2010-09-15 Toltec Pharmaceuticals, Llc Compositions and methods for treating vaginal infections and pathogenic vaginal biofilms
EP2227213A4 (en) * 2007-11-30 2011-01-05 Toltec Pharmaceuticals Llc Compositions and methods for treating vaginal infections and pathogenic vaginal biofilms
EP2529723A3 (en) * 2007-11-30 2013-04-03 Toltec Pharmaceuticals, Llc Compositions and Methods for Treating Vaginal Infections and Pathogenic Vaginal Biofilms
EP2684574A1 (en) * 2007-11-30 2014-01-15 Toltec Pharmaceuticals, Llc Compositions and methods for treating vaginal infections and pathogenic vaginal biofilms
US8956663B2 (en) 2007-11-30 2015-02-17 Toltec Pharmaceuticals, Llc Compositions and methods for treating vaginal infections and pathogenic vaginal biofilms

Also Published As

Publication number Publication date
FR2437833B1 (en) 1981-07-31

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Legal Events

Date Code Title Description
ST Notification of lapse