[go: up one dir, main page]
More Web Proxy on the site http://driver.im/

FR2416012A1 - Derives de l'imidazole et medicament contenant ces substances - Google Patents

Derives de l'imidazole et medicament contenant ces substances

Info

Publication number
FR2416012A1
FR2416012A1 FR7902450A FR7902450A FR2416012A1 FR 2416012 A1 FR2416012 A1 FR 2416012A1 FR 7902450 A FR7902450 A FR 7902450A FR 7902450 A FR7902450 A FR 7902450A FR 2416012 A1 FR2416012 A1 FR 2416012A1
Authority
FR
France
Prior art keywords
imidazole
derivatives
substances
products containing
medicinal products
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
FR7902450A
Other languages
English (en)
Other versions
FR2416012B1 (fr
Inventor
Peter Brian Thorogood
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Wellcome Foundation Ltd
Original Assignee
Wellcome Foundation Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Wellcome Foundation Ltd filed Critical Wellcome Foundation Ltd
Publication of FR2416012A1 publication Critical patent/FR2416012A1/fr
Application granted granted Critical
Publication of FR2416012B1 publication Critical patent/FR2416012B1/fr
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/56—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, attached to ring carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/415—1,2-Diazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445—Non condensed piperidines, e.g. piperocaine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
    • A61K31/485—Morphinan derivatives, e.g. morphine, codeine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
    • A61K31/52—Purines, e.g. adenine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/535—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C17/00—Preparation of halogenated hydrocarbons
    • C07C17/093—Preparation of halogenated hydrocarbons by replacement by halogens
    • C07C17/16—Preparation of halogenated hydrocarbons by replacement by halogens of hydroxyl groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
    • C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
    • C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D231/12—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/66—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D233/84—Sulfur atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D249/00—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
    • C07D249/02—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
    • C07D249/08—1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D319/00—Heterocyclic compounds containing six-membered rings having two oxygen atoms as the only ring hetero atoms
    • C07D319/10—1,4-Dioxanes; Hydrogenated 1,4-dioxanes
    • C07D319/14—1,4-Dioxanes; Hydrogenated 1,4-dioxanes condensed with carbocyclic rings or ring systems
    • C07D319/16—1,4-Dioxanes; Hydrogenated 1,4-dioxanes condensed with carbocyclic rings or ring systems condensed with one six-membered ring
    • C07D319/20—1,4-Dioxanes; Hydrogenated 1,4-dioxanes condensed with carbocyclic rings or ring systems condensed with one six-membered ring with substituents attached to the hetero ring

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Emergency Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Medicinal Preparation (AREA)

Abstract

L'invention concerne des dérivés de l'imidazole. Ils sont caractérisés par la formule générale :
FR7902450A 1978-02-01 1979-01-31 Derives de l'imidazole et medicament contenant ces substances Granted FR2416012A1 (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB398478 1978-02-01

Publications (2)

Publication Number Publication Date
FR2416012A1 true FR2416012A1 (fr) 1979-08-31
FR2416012B1 FR2416012B1 (fr) 1983-07-22

Family

ID=9768613

Family Applications (2)

Application Number Title Priority Date Filing Date
FR7902450A Granted FR2416012A1 (fr) 1978-02-01 1979-01-31 Derives de l'imidazole et medicament contenant ces substances
FR7923318A Granted FR2429593A1 (fr) 1978-02-01 1979-09-19 Medicaments contenant des derives d'imidazole

Family Applications After (1)

Application Number Title Priority Date Filing Date
FR7923318A Granted FR2429593A1 (fr) 1978-02-01 1979-09-19 Medicaments contenant des derives d'imidazole

Country Status (26)

Country Link
US (2) US4528195A (fr)
EP (2) EP0003732B1 (fr)
JP (1) JPS54145665A (fr)
AT (1) AT372949B (fr)
AU (1) AU533272B2 (fr)
BE (1) BE873849A (fr)
CA (2) CA1146549A (fr)
CH (1) CH643736A5 (fr)
DE (3) DE2862340D1 (fr)
DK (1) DK41479A (fr)
ES (1) ES477305A1 (fr)
FI (1) FI790314A (fr)
FR (2) FR2416012A1 (fr)
GB (2) GB2018136B (fr)
GR (1) GR65609B (fr)
HU (1) HU182629B (fr)
IE (1) IE47649B1 (fr)
IL (1) IL56556A (fr)
IT (1) IT1115800B (fr)
LU (1) LU80863A1 (fr)
MC (1) MC1241A1 (fr)
NL (1) NL7900807A (fr)
NZ (1) NZ189520A (fr)
PT (1) PT69165A (fr)
SE (1) SE7900834L (fr)
ZA (1) ZA79412B (fr)

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2428632A1 (fr) * 1978-06-13 1980-01-11 Kissei Pharmaceutical Derives d'imidazole pour le traitement des thromboses
FR2723369A1 (fr) * 1994-08-02 1996-02-09 Roussel Uclaf Nouveaux derives de l'imidazole, leur procede de preparation, les nouveaux intermediaires obtenus, leur application a titre de medicaments et les compositions pharmaceutiques les renfermant.
FR2723370A1 (fr) * 1994-08-02 1996-02-09 Roussel Uclaf Nouveaux derives de l'imidazole, leur procede de preparation, les nouveaux intermediaires obtenus, leur application a titre de medicaments et les compositions pharmaceutiques les renfermant

Families Citing this family (58)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK75680A (da) * 1979-02-22 1980-08-23 Wellcome Found Fremgangsmaade til fremstilling af 1-substituerede imidazoler
GR73560B (fr) * 1979-02-24 1984-03-15 Pfizer
DK157860C (da) * 1979-06-07 1990-07-30 Shionogi & Co Analogifremgangsmaade til fremstilling af benzylimidazolderivater samt farmaceutisk acceptable syreadditionssalte deraf
US4218461A (en) * 1979-08-15 1980-08-19 E. R. Squibb & Sons, Inc. 2,3-Dihydro-2-[(1H-imidazol-1-yl)-methylene]-1H-inden-1-ones
PH16249A (en) * 1980-02-04 1983-08-16 Reckitt & Colmann Prod Ltd Imidazoline derivatives,its pharmaceutical composition and method of use
US4321272A (en) * 1980-08-25 1982-03-23 Syntex (U.S.A.) Inc. Derivatives of substituted N-alkylimidazoles
NL8005204A (nl) * 1980-09-17 1982-04-16 Gist Brocades Nv Ethenyl-imidazool-derivaten met antimycotische werkzaamheid.
GR75101B (fr) * 1980-10-23 1984-07-13 Pfizer
JPS6036427B2 (ja) * 1980-12-05 1985-08-20 塩野義製薬株式会社 １−ベンジルイミダゾ−ル誘導体
DE3103068A1 (de) * 1981-01-30 1982-08-26 Basf Ag, 6700 Ludwigshafen Vinylazole, verfahren zu ihrer herstellung und ihre verwendung bei der bekaempfung von pilzen
AU559687B2 (en) * 1981-07-01 1987-03-19 Upjohn Company, The Pyridinyl-and imidazolyl-benzofurane and benzothiophenes
ZA825413B (en) * 1981-08-26 1983-06-29 Pfizer Thromboxane synthetase inhibitors, processes for their production, and pharmaceutical compositions comprising them
GB2115408B (en) * 1982-02-09 1985-10-16 Ici Plc Triazole and imidazole derivatives
EP0091503A1 (fr) * 1982-04-14 1983-10-19 Gist-Brocades N.V. Procédé pour combattre des infections fongiques
IE55848B1 (en) * 1982-08-14 1991-01-30 Wellcome Found Imidazole derivatives and salts thereof,their synthesis,and pharmaceutical formulations
JPS59225183A (ja) * 1983-02-01 1984-12-18 Yoshitomi Pharmaceut Ind Ltd ジヒドロベンゾフラン誘導体
EP0121081B1 (fr) * 1983-03-03 1991-01-30 BASF Aktiengesellschaft Azolylméthylcycloalcanes, leur procédé de préparation et leur application thérapeutique
US4536505A (en) * 1983-05-17 1985-08-20 Ciba-Geigy Corporation Certain N-(pyridyl) indoles
PH22076A (en) * 1983-08-25 1988-05-20 Daiichi Seiyaku Co Benzocycloalkane derivative
IT1212791B (it) * 1983-11-24 1989-11-30 Medea Res Srl Derivato imidazolico adattivita' vasodilatatrice ed antitrombotica, sua preparazione e composizioni farmaceutiche che lo contengono.
DE3470881D1 (de) * 1983-12-20 1988-06-09 Ciba Geigy Ag Microbizides
EP0149976A3 (fr) * 1983-12-30 1986-12-10 Ciba-Geigy Ag Imidazoles substitués
US4593029A (en) * 1984-02-15 1986-06-03 Syntex (U.S.A.) Inc. Novel ω-(N-imidazolyl)alkyl ethers of 1,2,3,5-tetrahydroimidazo[2,1-b]quinazolin-2-ones
US4659730A (en) * 1984-06-18 1987-04-21 Eli Lilly And Company Aromatase inhibiting imidazole derivatives
JPS61110266A (ja) * 1984-11-05 1986-05-28 Omron Tateisi Electronics Co カード発行方法
US4609733A (en) * 1984-12-27 1986-09-02 Ciba-Geigy Corporation 3-keto-substituted-N-pyridylindoles
DE3508905A1 (de) * 1985-03-13 1986-09-18 Hoechst Ag, 6230 Frankfurt Neue imidazolylverbindungen und verfahren zu ihrer herstellung
IL81264A (en) * 1986-01-30 1990-11-05 Takeda Chemical Industries Ltd Quinone derivatives,their production and pharmaceutical compositions containing them
US5229385A (en) * 1986-01-30 1993-07-20 Takeda Chemical Industries, Ltd. Quinone derivatives, their production and use
US4749713A (en) * 1986-03-07 1988-06-07 Ciba-Geigy Corporation Alpha-heterocycle substituted tolunitriles
JP2581556B2 (ja) * 1986-05-06 1997-02-12 メレルダウファーマスーティカルズ インコーポレーテッド 新規なドパミンベ−タヒドロキシラ−ゼ抑制剤
KR930004646B1 (ko) * 1986-12-09 1993-06-02 다나베 세이야꾸 가부시끼가이샤 심기능 부전의 예방 및 치료제
EP0285356A3 (fr) * 1987-03-30 1989-05-31 Smithkline Beecham Corporation Inhibiteurs de dopamine-bèta-hydroxylase
US4837333A (en) * 1987-05-14 1989-06-06 G. D. Searle & Co. Substituted alkylidene imidazoles
DE3811574A1 (de) * 1988-03-31 1989-10-19 Schering Ag N-substituierte imidazole, verfahren zu ihrer herstellung sowie ihre verwendung in arzneimitteln
IL91542A0 (en) * 1988-10-06 1990-04-29 Erba Carlo Spa N-imidazolyl-and n-imidazolyl-methyl derivatives of substituted bicyclic compounds,their preparation and pharmaceutical compositions containing them
JPH0710862B2 (ja) * 1989-08-08 1995-02-08 宇部興産株式会社 アゾリジン誘導体、その製法及び農園芸用殺菌剤
JPH03115267A (ja) * 1989-09-28 1991-05-16 Maruho Kk プロピオフエノン誘導体、その製造方法、それを含む中枢性筋弛緩剤および抗痙攣剤
US5073566A (en) * 1989-11-30 1991-12-17 Eli Lilly And Company Angiotensin ii antagonist 1,3-imidazoles and use thereas
US5635521A (en) * 1991-09-23 1997-06-03 Sandoz Ltd. Imidazolylmethyl-pyridines
DE4131584A1 (de) * 1991-09-23 1993-03-25 Sandoz Ag Imidazolylmethyl-pyridine, ihre herstellung und anwendung als pharmazeutika
DE69212844T2 (de) * 1991-12-18 1997-01-09 Schering Corp., Kenilworth, N.J. Imidazolyl oder imidazolylalkyl substituiert mit einem 4- oder 5-gliedrigen stickstoff enthaltenden heterozyklischen ring
GB9127304D0 (en) * 1991-12-23 1992-02-19 Boots Co Plc Therapeutic agents
US5612360A (en) * 1992-06-03 1997-03-18 Eli Lilly And Company Angiotensin II antagonists
US5401851A (en) * 1992-06-03 1995-03-28 Eli Lilly And Company Angiotensin II antagonists
US5359073A (en) * 1992-11-24 1994-10-25 G. D. Searle & Co. Substituted-phenyl (N,N'-cycloalkyl/alkyl carboxamide)-1H/3H-imidazo[4,5-b]pyridine compounds as PAF antagonists
US5262426A (en) * 1993-01-22 1993-11-16 G. D. Searle & Co. N,N'-cycloalkyl/alkyl carboxamide 4H-imidazo-[4,5-b]pyridine compounds as PAF antagonists
US5360907A (en) * 1993-06-14 1994-11-01 G.D. Searle & Co. Pyrrolo[3,2-B]pyridinylalkyl benzamide derivatives
GB9312893D0 (en) * 1993-06-22 1993-08-04 Boots Co Plc Therapeutic agents
WO1995029901A1 (fr) * 1994-04-28 1995-11-09 Uniroyal Chemical Company, Inc. Derives azoles fongicides
US5652363A (en) * 1995-10-05 1997-07-29 C.D. Searle & Co. Pyrido-1,4-oxazinylalkyl-benzamide derivatives
FR2757511B1 (fr) * 1996-12-23 2001-05-04 Sanofi Sa Procede pour la preparation d'un derive de tetrahydropyridine
US5855869A (en) * 1996-12-31 1999-01-05 Rhodia Inc. Microparticulate abrasives
AU4537400A (en) * 1999-05-12 2000-12-05 Neurosearch A/S Ion channel modulating agents
JP2002262119A (ja) 2001-02-28 2002-09-13 Sharp Corp 画像処理装置、画像処理方法、画像処理プログラムを記録した機械読取可能な記録媒体および画像処理プログラム
JP5165154B2 (ja) * 2010-04-27 2013-03-21 日本製紙株式会社 細胞分化促進剤およびその用途
US9394290B2 (en) * 2010-10-21 2016-07-19 Universitaet Des Saarlandes Campus Saarbruecken Selective CYP11B1 inhibitors for the treatment of cortisol dependent diseases
CN104334565A (zh) 2012-05-29 2015-02-04 莫门蒂夫性能材料有限责任公司 异氰酸基硅烷的制备

Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2070102A1 (en) * 1969-10-01 1971-09-10 Continental Pharma 1 subst phenyl 2 amino ethanols useful as beta - adrenergic agents peripheral vasodilators and hypo-
FR2115153A1 (en) * 1970-11-30 1972-07-07 Berlin Chemie Veb 1-acyl-imidazoles - with antiviral activity
FR2249616A1 (en) * 1973-10-31 1975-05-30 Pepro Fungicidal compositions contg 1-aralkyl benzimidazoles - for treatment of plants and seeds
US3927017A (en) * 1974-06-27 1975-12-16 Janssen Pharmaceutica Nv 1-({62 -Aryl-{62 -R-ethyl)imidazoles
DE2533211A1 (de) * 1975-07-24 1977-02-10 Heumann Ludwig & Co Gmbh Verfahren zur herstellung von imidazolderivaten
GB1533706A (en) * 1976-03-01 1978-11-29 Ici Ltd Fungicidal imidazoles and 1,2,4-triazoles

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE488681C (de) * 1927-02-27 1930-01-06 I G Farbenindustrie Akt Ges Verfahren zur Darstellung von Imidazolderivaten
DE1620362A1 (de) * 1966-05-04 1970-04-02 Shell Int Research Verfahren zur Herstellung von N-Alkyl- bzw.N-Alkenylimidazolen
US3592826A (en) * 1967-05-22 1971-07-13 Union Carbide Corp Imidazole catalysts for diketene reactions
GB1321701A (en) * 1969-10-01 1973-06-27 Continental Pharma Amino-alcohols their salts and process for prepairing the same
GB1364312A (en) * 1972-01-25 1974-08-21 Beecham Group Ltd Biologically active imidazoles
FR2215153A5 (fr) * 1973-01-19 1974-08-19 Cit Alcatel
JPS5437953B2 (fr) * 1974-04-25 1979-11-17
US4036975A (en) * 1975-07-28 1977-07-19 Xyntex (U.S.A) Inc. 1-[2-(1-Adamantyl)-2-(R-thio)ethyl]imidazoles and 1-[2-(1-adamantyl)-2-(R-oxy)ethyl]imidazoles
US4118461A (en) * 1975-12-18 1978-10-03 Rohm And Haas Company 1-Substituted aralkyl imidazoles
US4150153A (en) * 1977-05-13 1979-04-17 Syntex (U.S.A.) Inc. 1-(Naphthylethyl)imidazole derivatives
US4284641A (en) * 1977-08-26 1981-08-18 Burroughs Wellcome Co. Pharmaceutically active imidazole derivatives

Patent Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2070102A1 (en) * 1969-10-01 1971-09-10 Continental Pharma 1 subst phenyl 2 amino ethanols useful as beta - adrenergic agents peripheral vasodilators and hypo-
FR2115153A1 (en) * 1970-11-30 1972-07-07 Berlin Chemie Veb 1-acyl-imidazoles - with antiviral activity
FR2249616A1 (en) * 1973-10-31 1975-05-30 Pepro Fungicidal compositions contg 1-aralkyl benzimidazoles - for treatment of plants and seeds
US3927017A (en) * 1974-06-27 1975-12-16 Janssen Pharmaceutica Nv 1-({62 -Aryl-{62 -R-ethyl)imidazoles
DE2533211A1 (de) * 1975-07-24 1977-02-10 Heumann Ludwig & Co Gmbh Verfahren zur herstellung von imidazolderivaten
GB1533706A (en) * 1976-03-01 1978-11-29 Ici Ltd Fungicidal imidazoles and 1,2,4-triazoles

Cited By (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2428632A1 (fr) * 1978-06-13 1980-01-11 Kissei Pharmaceutical Derives d'imidazole pour le traitement des thromboses
FR2723369A1 (fr) * 1994-08-02 1996-02-09 Roussel Uclaf Nouveaux derives de l'imidazole, leur procede de preparation, les nouveaux intermediaires obtenus, leur application a titre de medicaments et les compositions pharmaceutiques les renfermant.
FR2723370A1 (fr) * 1994-08-02 1996-02-09 Roussel Uclaf Nouveaux derives de l'imidazole, leur procede de preparation, les nouveaux intermediaires obtenus, leur application a titre de medicaments et les compositions pharmaceutiques les renfermant
WO1996004275A1 (fr) * 1994-08-02 1996-02-15 Roussel Uclaf Nouveaux derives de l'imidazole, leur procede de preparation, les nouveaux intermediaires obtenus, leur application a titre de medicaments et les compositions pharmaceutiques les renfermant
WO1996004276A1 (fr) * 1994-08-02 1996-02-15 Roussel Uclaf Nouvelle utilisation et nouveaux derives de l'imidazole, leur procede de preparation, les nouveaux intermediaires obtenus, leur application a titre de medicaments et les compositions pharmaceutiques les renfermant
US5811444A (en) * 1994-08-02 1998-09-22 Roussel Uclaf Compositions for reducing abnormal stimulation of endothelin receptors and novel compounds
US5856509A (en) * 1994-08-02 1999-01-05 Roussel Uclaf Derivatives of imidazole, their preparation process, the new intermediates obtained, their use as medicaments and the pharmaceutical compositions containing them

Also Published As

Publication number Publication date
EP0003560B1 (fr) 1984-05-02
CA1162855A (fr) 1984-02-28
BE873849A (fr) 1979-07-31
FR2429593A1 (fr) 1980-01-25
GR65609B (en) 1980-10-14
US4528195A (en) 1985-07-09
SE7900834L (sv) 1979-08-02
DE2903653A1 (de) 1979-08-02
PT69165A (en) 1979-02-01
DK41479A (da) 1979-08-02
GB2018136A (en) 1979-10-17
IE790177L (en) 1979-08-01
JPS54145665A (en) 1979-11-14
EP0003560A3 (en) 1979-10-31
NL7900807A (nl) 1979-08-03
EP0003560A2 (fr) 1979-08-22
LU80863A1 (fr) 1979-09-07
CA1146549A (fr) 1983-05-17
ATA70979A (de) 1983-04-15
AU4380879A (en) 1979-08-09
IL56556A (en) 1984-02-29
NZ189520A (en) 1985-01-31
DE2966948D1 (en) 1984-06-07
IT7947847A0 (it) 1979-01-31
ES477305A1 (es) 1980-01-16
AU533272B2 (en) 1983-11-17
GB2098064A (en) 1982-11-17
FR2416012B1 (fr) 1983-07-22
FR2429593B1 (fr) 1983-09-16
IE47649B1 (en) 1984-05-16
GB2018136B (en) 1983-02-02
EP0003732A2 (fr) 1979-09-05
FI790314A (fi) 1979-08-02
DE2862340D1 (en) 1983-11-24
IT1115800B (it) 1986-02-03
EP0003732B1 (fr) 1983-10-19
CH643736A5 (de) 1984-06-29
US4416895A (en) 1983-11-22
IL56556A0 (en) 1979-03-12
MC1241A1 (fr) 1979-10-26
AT372949B (de) 1983-11-25
ZA79412B (en) 1980-09-24
HU182629B (en) 1984-02-28
GB2098064B (en) 1983-04-07
EP0003732A3 (en) 1979-10-17

Similar Documents

Publication Publication Date Title
FR2416012A1 (fr) Derives de l'imidazole et medicament contenant ces substances
FR2392971A1 (fr) Derives de l'acide prostanoique, leur preparation et medicament contenant ces substances
FR2367053A1 (fr) Nouveaux derives de phenoxy-amino-propanol, leur preparation et leur application en tant que medicaments
FR2360587A1 (fr) Nouveaux derives d'amino-alcoyl-furannes utiles comme medicaments
FR2398748A1 (fr) Nouveaux derives d'imidazoquinazoline, leur preparation et leur application en tant que medicaments
FR2361901A1 (fr) Derives de substitution de nucleotides et medicament contenant ces substances
FR2400512A1 (fr) Nouveaux nitro-imidazoles, leur preparation et leur application en tant que medicaments
FR2422620A1 (fr) Derives du stilbene, leur preparation et leur application en tant que medicaments
FR2422643A1 (fr) Nouveaux derives d'imidazolidine, leur preparation et leur application comme medicaments
FR2432511A1 (fr) Derives triazoliques, leur preparation et leur application en tant que medicaments
FR2416888A1 (fr) Nouveaux derives de phenyl-piperazine utiles comme medicaments
FR2433512A1 (fr) Derives de l'indane et medicaments qui en contiennent
FR2370732A1 (fr) Derives polysubstitues de la piperidine, leurs procedes de preparation et leur application en tant que medicaments
FR2354761A1 (fr) Acides n-aryl-anthraniliques, leurs procedes de preparation et compositions pharmaceutiques contenant lesdits acides anthraniliques
FR2363330A1 (fr) Medicament destine a reduire la fertilite chez les mammiferes
FR2432519A1 (fr) Nouveaux derives de purine et medicament les contenant
FR2415103A1 (fr) Acides et derives d'acides 4-pyridone-3-carboxyliques, leur preparation et leur application en tant que medicaments
FR2417502A1 (fr) Nouvelles 2-phenylimino-imidazolidines substituees, leurs sels d'addition avec des acides, medicaments les renfermant et procedes pour leur preparation
FR2422405A1 (fr) Nouveaux medicaments constitues de derives de l'acide p-aminobenzoique
FR2415636A1 (fr) Nouveaux derives de la guanidine, leur preparation et leur application comme medicaments
FR2420346A1 (fr) Medicaments contenant des alcenylxanthines et leur procede de preparation
FR2405067A1 (fr) Compositions pharmaceutiques contenant des derives monofonctionnels du psoralene pour le traitement des affections cutanees
FR2361361A1 (fr) Nouveaux derives du cyclopentane et medicaments contenant ces substances
FR2390424A1 (fr) Nouveaux derives d'amides de l'acide phenylacetique substitues, leur application en tant que medicament et leur application
FR2401160A1 (fr) Nouveaux derives d'esters de vincaminol, leur preparation et leur application en tant que medicaments

Legal Events

Date Code Title Description
ST Notification of lapse