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FR2334681A1 - Nouveaux derives de l'acide lysergique et leur preparation - Google Patents

Nouveaux derives de l'acide lysergique et leur preparation

Info

Publication number
FR2334681A1
FR2334681A1 FR7702636A FR7702636A FR2334681A1 FR 2334681 A1 FR2334681 A1 FR 2334681A1 FR 7702636 A FR7702636 A FR 7702636A FR 7702636 A FR7702636 A FR 7702636A FR 2334681 A1 FR2334681 A1 FR 2334681A1
Authority
FR
France
Prior art keywords
preparation
new
acid derivatives
lysergic acid
lysergic
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
FR7702636A
Other languages
English (en)
Other versions
FR2334681B1 (fr
Inventor
Theodor Fehr
Paul Stadler
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sandoz AG
Original Assignee
Sandoz AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sandoz AG filed Critical Sandoz AG
Publication of FR2334681A1 publication Critical patent/FR2334681A1/fr
Application granted granted Critical
Publication of FR2334681B1 publication Critical patent/FR2334681B1/fr
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D457/00—Heterocyclic compounds containing indolo [4, 3-f, g] quinoline ring systems, e.g. derivatives of ergoline, of the formula:, e.g. lysergic acid
    • C07D457/04—Heterocyclic compounds containing indolo [4, 3-f, g] quinoline ring systems, e.g. derivatives of ergoline, of the formula:, e.g. lysergic acid with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached in position 8
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/02—Non-specific cardiovascular stimulants, e.g. drugs for syncope, antihypotensives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D519/00—Heterocyclic compounds containing more than one system of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring system not provided for in groups C07D453/00 or C07D455/00
    • C07D519/02—Ergot alkaloids of the cyclic peptide type

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Peptides Or Proteins (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Pyridine Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
FR7702636A 1973-11-28 1977-01-31 Nouveaux derives de l'acide lysergique et leur preparation Granted FR2334681A1 (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CH1669873A CH587858A5 (fr) 1973-11-28 1973-11-28

Publications (2)

Publication Number Publication Date
FR2334681A1 true FR2334681A1 (fr) 1977-07-08
FR2334681B1 FR2334681B1 (fr) 1980-04-18

Family

ID=4419482

Family Applications (2)

Application Number Title Priority Date Filing Date
FR7439049A Expired FR2252098B1 (fr) 1973-11-28 1974-11-28
FR7702636A Granted FR2334681A1 (fr) 1973-11-28 1977-01-31 Nouveaux derives de l'acide lysergique et leur preparation

Family Applications Before (1)

Application Number Title Priority Date Filing Date
FR7439049A Expired FR2252098B1 (fr) 1973-11-28 1974-11-28

Country Status (25)

Country Link
US (1) US4229451A (fr)
JP (1) JPS5919116B2 (fr)
AT (1) AT352911B (fr)
BE (1) BE822729A (fr)
CA (1) CA1034572A (fr)
CH (1) CH587858A5 (fr)
CS (1) CS176291B2 (fr)
DD (1) DD115119A5 (fr)
DE (1) DE2454619A1 (fr)
DK (1) DK143804C (fr)
ES (1) ES432288A1 (fr)
FI (1) FI59254C (fr)
FR (2) FR2252098B1 (fr)
GB (2) GB1496491A (fr)
HK (1) HK54080A (fr)
HU (1) HU168859B (fr)
IE (1) IE41767B1 (fr)
IL (1) IL46128A (fr)
MY (1) MY8100185A (fr)
NL (1) NL7415250A (fr)
NO (1) NO744175L (fr)
PH (1) PH13669A (fr)
SE (2) SE417319B (fr)
SU (1) SU516355A3 (fr)
ZA (1) ZA747603B (fr)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH601321A5 (fr) * 1975-01-06 1978-07-14 Sandoz Ag
CH619468A5 (fr) * 1976-01-12 1980-09-30 Sandoz Ag
DE3020895A1 (de) * 1979-06-12 1980-12-18 Sandoz Ag Ergopeptinderivate, verfahren zu deren herstellung sowie diese ergopeptinderivate enthaltende pharmazeutischen zusammensetzungen
US5069911A (en) * 1985-02-05 1991-12-03 Sandoz Ltd. Pharmaceutical 9,10-dihydrogenated ergot alkaloid containing compositions
US7771746B2 (en) * 1999-12-03 2010-08-10 Polichem Sa Methods for making sustained-release pharmaceutical compositions of ergot alkaloids having improved bioavailability and compositions thereof
GB0409785D0 (en) * 2004-04-30 2004-06-09 Resolution Chemicals Ltd Preparation of cabergoline
US7339060B2 (en) 2005-03-23 2008-03-04 Resolution Chemicals, Ltd. Preparation of cabergoline
GB0505965D0 (en) * 2005-03-23 2005-04-27 Resolution Chemicals Ltd Preparation of cabergoline
US20070197576A1 (en) * 2006-02-08 2007-08-23 Resolution Chemicals Limited Production of Cabergoline and Novel Polymorphic Form Thereof

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2619488A (en) * 1952-11-25 Method of preparing d
GB769260A (en) * 1954-04-07 1957-03-06 Sandoz Ltd Process for the preparation of isomeric racemic dihydrolysergic acids and their homologues
DE1006425B (de) * 1954-04-07 1957-04-18 Sandoz Ag Verfahren zur Herstellung der isomeren racemischen Dihydrolysergsaeuren und ihren Homologen
GB1011112A (en) * 1961-05-10 1965-11-24 Sandoz Ag Improvements in or relating to ergot alkaloids
CH469006A (de) * 1965-07-07 1969-02-28 Sandoz Ag Verfahren zur Herstellung neuer synthetischer Alkaloide
CH469735A (de) * 1965-11-02 1969-03-15 Sandoz Ag Verfahren zur Herstellung heterocyclischer Verbindungen
GB1298277A (en) * 1969-04-18 1972-11-29 Sandoz Ltd Preparation of ergot peptide alkaloids
CH534683A (de) * 1970-05-26 1973-03-15 Sandoz Ag Verfahren zur Herstellung neuer Mutterkornpeptidalkaloide
CH601321A5 (fr) * 1975-01-06 1978-07-14 Sandoz Ag
US4138565A (en) * 1975-05-31 1979-02-06 Sandoz Ltd. Stable solutions and processes for their preparation

Also Published As

Publication number Publication date
US4229451A (en) 1980-10-21
MY8100185A (en) 1981-12-31
CH587858A5 (fr) 1977-05-13
JPS5919116B2 (ja) 1984-05-02
SE7710418L (sv) 1977-09-16
FI334574A (fr) 1975-05-29
SE7414607L (fr) 1975-05-29
NL7415250A (nl) 1975-05-30
IE41767L (en) 1975-05-28
SE417319B (sv) 1981-03-09
FI59254B (fi) 1981-03-31
FR2334681B1 (fr) 1980-04-18
DD115119A5 (fr) 1975-09-12
BE822729A (fr) 1975-05-28
IE41767B1 (en) 1980-03-26
CS176291B2 (fr) 1977-06-30
DK143804B (da) 1981-10-12
DK600374A (fr) 1975-07-28
ATA945174A (de) 1979-03-15
FR2252098B1 (fr) 1978-06-30
FI59254C (fi) 1981-07-10
HK54080A (en) 1980-10-03
IL46128A0 (en) 1975-02-10
ES432288A1 (es) 1977-02-16
GB1496492A (en) 1977-12-30
HU168859B (fr) 1976-07-28
PH13669A (en) 1980-08-26
FR2252098A1 (fr) 1975-06-20
CA1034572A (fr) 1978-07-11
ZA747603B (en) 1976-07-28
AU7582674A (en) 1976-05-27
SU516355A3 (ru) 1976-05-30
DE2454619A1 (de) 1975-06-05
NO744175L (fr) 1975-06-23
GB1496491A (en) 1977-12-30
IL46128A (en) 1977-10-31
SE424869B (sv) 1982-08-16
JPS5084599A (fr) 1975-07-08
AT352911B (de) 1979-10-10
DK143804C (da) 1982-03-29

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Legal Events

Date Code Title Description
ST Notification of lapse