FR2324304A2 - Nouveaux derives de l'acide 3-quinoleine carboxylique, leur procede de preparation et leur application comme medicament - Google Patents
Nouveaux derives de l'acide 3-quinoleine carboxylique, leur procede de preparation et leur application comme medicamentInfo
- Publication number
- FR2324304A2 FR2324304A2 FR7528939A FR7528939A FR2324304A2 FR 2324304 A2 FR2324304 A2 FR 2324304A2 FR 7528939 A FR7528939 A FR 7528939A FR 7528939 A FR7528939 A FR 7528939A FR 2324304 A2 FR2324304 A2 FR 2324304A2
- Authority
- FR
- France
- Prior art keywords
- quinoline
- hydroxy
- thiazolyl
- prepd
- analgesic
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
- C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
- C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D215/48—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
- C07D215/54—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen attached in position 3
- C07D215/56—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen attached in position 3 with oxygen atoms in position 4
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
FR7528939A FR2324304A2 (fr) | 1975-09-22 | 1975-09-22 | Nouveaux derives de l'acide 3-quinoleine carboxylique, leur procede de preparation et leur application comme medicament |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
FR7528939A FR2324304A2 (fr) | 1975-09-22 | 1975-09-22 | Nouveaux derives de l'acide 3-quinoleine carboxylique, leur procede de preparation et leur application comme medicament |
Publications (2)
Publication Number | Publication Date |
---|---|
FR2324304A2 true FR2324304A2 (fr) | 1977-04-15 |
FR2324304B2 FR2324304B2 (fr) | 1978-09-01 |
Family
ID=9160268
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
FR7528939A Granted FR2324304A2 (fr) | 1975-09-22 | 1975-09-22 | Nouveaux derives de l'acide 3-quinoleine carboxylique, leur procede de preparation et leur application comme medicament |
Country Status (1)
Country | Link |
---|---|
FR (1) | FR2324304A2 (fr) |
Cited By (12)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0012639A2 (fr) * | 1978-12-08 | 1980-06-25 | Roussel-Uclaf | Nouveaux dérivés de l'acide 3-quinoléine carboxylique, leur procédé de préparation, leur application comme médicament et les compositions pharmaceutiques les renfermant |
FR2507602A1 (fr) * | 1981-06-12 | 1982-12-17 | Roussel Uclaf | Nouveau derive dihydrothiazole de la quinoleine, ses sels, procede de preparation, application a titre de medicaments et compositions les renfermant |
EP0067772A1 (fr) * | 1981-06-12 | 1982-12-22 | Roussel-Uclaf | Nouveaux dérivés du N-dihydrothiazolyl 3-quinoléine carboxamide, leurs sels, leur procédé de préparation, leur application à titre de médicaments et les compositions les renfermant |
EP0317991A2 (fr) * | 1987-11-27 | 1989-05-31 | Hoechst-Roussel Pharmaceuticals Incorporated | 3-Carboxamides de la 1-arylquinoléine et de la 1-arylisoquinoléine, un procédé de leur préparation et leur utilisation comme médicaments |
US7495103B2 (en) | 2004-06-24 | 2009-02-24 | Vertex Pharmaceuticals Incorporated | Modulators of ATP-binding cassette transporters |
US8354427B2 (en) | 2004-06-24 | 2013-01-15 | Vertex Pharmaceutical Incorporated | Modulators of ATP-binding cassette transporters |
US8802700B2 (en) | 2010-12-10 | 2014-08-12 | Vertex Pharmaceuticals Incorporated | Modulators of ATP-Binding Cassette transporters |
US9139530B2 (en) | 2005-12-28 | 2015-09-22 | Vertex Pharmaceuticals Incorporated | Solid forms of N-[2,4-bis(1,1-dimethylethyl)-5-hydroxyphenyl]-1,4-dihydro-4-oxoquinoline-3-carboxamide |
US9701639B2 (en) | 2014-10-07 | 2017-07-11 | Vertex Pharmaceuticals Incorporated | Co-crystals of modulators of cystic fibrosis transmembrane conductance regulator |
US9751839B2 (en) | 2009-03-20 | 2017-09-05 | Vertex Pharmaceuticals Incorporated | Process for making modulators of cystic fibrosis transmembrane conductance regulator |
US10272046B2 (en) | 2012-02-27 | 2019-04-30 | Vertex Pharmaceuticals Incorporated | Pharmaceutical composition and administrations thereof |
US10646481B2 (en) | 2008-08-13 | 2020-05-12 | Vertex Pharmaceuticals Incorporated | Pharmaceutical composition and administrations thereof |
Citations (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR2218896A1 (fr) * | 1973-02-26 | 1974-09-20 | Allen & Hanburys Ltd |
-
1975
- 1975-09-22 FR FR7528939A patent/FR2324304A2/fr active Granted
Patent Citations (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR2218896A1 (fr) * | 1973-02-26 | 1974-09-20 | Allen & Hanburys Ltd |
Cited By (29)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0012639A2 (fr) * | 1978-12-08 | 1980-06-25 | Roussel-Uclaf | Nouveaux dérivés de l'acide 3-quinoléine carboxylique, leur procédé de préparation, leur application comme médicament et les compositions pharmaceutiques les renfermant |
EP0012639A3 (en) * | 1978-12-08 | 1980-11-12 | Roussel-Uclaf | Quinolein-3-carboxylic acid derivatives, process for their preparation, their use in medicines and pharmaceutical compositions containing them |
EP0049555A1 (fr) * | 1978-12-08 | 1982-04-14 | Roussel-Uclaf | Nouveaux dérivés de l'acide 2-trifluorométhyl-4-hydroxy-3-quinoline carboxylique et leur procédé de préparation |
FR2507602A1 (fr) * | 1981-06-12 | 1982-12-17 | Roussel Uclaf | Nouveau derive dihydrothiazole de la quinoleine, ses sels, procede de preparation, application a titre de medicaments et compositions les renfermant |
EP0067772A1 (fr) * | 1981-06-12 | 1982-12-22 | Roussel-Uclaf | Nouveaux dérivés du N-dihydrothiazolyl 3-quinoléine carboxamide, leurs sels, leur procédé de préparation, leur application à titre de médicaments et les compositions les renfermant |
EP0317991A2 (fr) * | 1987-11-27 | 1989-05-31 | Hoechst-Roussel Pharmaceuticals Incorporated | 3-Carboxamides de la 1-arylquinoléine et de la 1-arylisoquinoléine, un procédé de leur préparation et leur utilisation comme médicaments |
EP0317991A3 (fr) * | 1987-11-27 | 1990-11-07 | Hoechst-Roussel Pharmaceuticals Incorporated | 3-Carboxamides de la 1-arylquinoléine et de la 1-arylisoquinoléine, un procédé de leur préparation et leur utilisation comme médicaments |
US8629162B2 (en) | 2004-06-24 | 2014-01-14 | Vertex Pharmaceuticals Incorporated | Modulators of ATP-binding cassette transporters |
US8101767B2 (en) | 2004-06-24 | 2012-01-24 | Vertex Pharmaceuticals Incorporated | Modulators of ATP-binding cassette transporters |
US8324242B2 (en) | 2004-06-24 | 2012-12-04 | Vertex Pharmaceutical Incorporated | Modulators of ATP-binding cassette transporters |
US8354427B2 (en) | 2004-06-24 | 2013-01-15 | Vertex Pharmaceutical Incorporated | Modulators of ATP-binding cassette transporters |
US8614327B2 (en) | 2004-06-24 | 2013-12-24 | Vertex Pharmaceuticals Incorporated | Modulators of ATP-binding cassette transporters |
US10662192B2 (en) | 2004-06-24 | 2020-05-26 | Vertex Pharmaceuticals Incorporated | Modulators of ATP-binding cassette transporters |
US8741925B2 (en) | 2004-06-24 | 2014-06-03 | Vertex Pharmaceuticals Incorporated | Modulators of ATP-binding cassette transporters |
US7495103B2 (en) | 2004-06-24 | 2009-02-24 | Vertex Pharmaceuticals Incorporated | Modulators of ATP-binding cassette transporters |
US9090619B2 (en) | 2004-06-24 | 2015-07-28 | Vertex Pharmaceuticals Incorporated | Modulators of ATP-binding cassette transporters |
US9139530B2 (en) | 2005-12-28 | 2015-09-22 | Vertex Pharmaceuticals Incorporated | Solid forms of N-[2,4-bis(1,1-dimethylethyl)-5-hydroxyphenyl]-1,4-dihydro-4-oxoquinoline-3-carboxamide |
US9670163B2 (en) | 2005-12-28 | 2017-06-06 | Vertex Pharmaceuticals Incorporated | Solid forms of N-[2,4-bis(1,1-dimethylethyl)-5-hydroxyphenyl]-1,4-dihydro-4-oxoquinoline-3-carboxamide |
US9931334B2 (en) | 2005-12-28 | 2018-04-03 | Vertex Pharmaceuticals Incorporated | Solid forms of N[2,4-bis(1,1-dimethylethyl)-5-hydroxyphenyl]-1,4-dihydro-4-oxoquinoline-3-carboxamide |
US11291662B2 (en) | 2005-12-28 | 2022-04-05 | Vertex Pharmaceuticals Incorporated | Solid forms of n-[2,4-bis(1,1-dimethylethyl)-5-hydroxyphenyl]-1,4-dihydro-4-oxoquinoline-3-carboxamide |
US10537565B2 (en) | 2005-12-28 | 2020-01-21 | Vertex Pharmaceuticals Incorporated | Solid forms of N-[2,4-bis(1,1-dimethylethyl)-5-hydroxyphenyl]-1,4-dihydro-4-oxoquinoline-3-carboxamide |
US11564916B2 (en) | 2008-08-13 | 2023-01-31 | Vertex Pharmaceuticals Incorporated | Pharmaceutical composition and administrations thereof |
US10646481B2 (en) | 2008-08-13 | 2020-05-12 | Vertex Pharmaceuticals Incorporated | Pharmaceutical composition and administrations thereof |
US9751839B2 (en) | 2009-03-20 | 2017-09-05 | Vertex Pharmaceuticals Incorporated | Process for making modulators of cystic fibrosis transmembrane conductance regulator |
US8802700B2 (en) | 2010-12-10 | 2014-08-12 | Vertex Pharmaceuticals Incorporated | Modulators of ATP-Binding Cassette transporters |
US11147770B2 (en) | 2012-02-27 | 2021-10-19 | Vertex Pharmaceuticals Incorporated | Pharmaceutical composition and administrations thereof |
US10272046B2 (en) | 2012-02-27 | 2019-04-30 | Vertex Pharmaceuticals Incorporated | Pharmaceutical composition and administrations thereof |
US11752106B2 (en) | 2012-02-27 | 2023-09-12 | Vertex Pharmaceuticals Incorporated | Pharmaceutical composition and administrations thereof |
US9701639B2 (en) | 2014-10-07 | 2017-07-11 | Vertex Pharmaceuticals Incorporated | Co-crystals of modulators of cystic fibrosis transmembrane conductance regulator |
Also Published As
Publication number | Publication date |
---|---|
FR2324304B2 (fr) | 1978-09-01 |
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