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FR2232311A1 - Antiarrhythmic khellin-quinol derivs. - comprising the t-butyl-amino-hydroxy-propyl and di-isopropyl-amino-ethyl ethers - Google Patents

Antiarrhythmic khellin-quinol derivs. - comprising the t-butyl-amino-hydroxy-propyl and di-isopropyl-amino-ethyl ethers

Info

Publication number
FR2232311A1
FR2232311A1 FR7320286A FR7320286A FR2232311A1 FR 2232311 A1 FR2232311 A1 FR 2232311A1 FR 7320286 A FR7320286 A FR 7320286A FR 7320286 A FR7320286 A FR 7320286A FR 2232311 A1 FR2232311 A1 FR 2232311A1
Authority
FR
France
Prior art keywords
amino
khellin
quinol
derivs
antiarrhythmic
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
FR7320286A
Other languages
French (fr)
Other versions
FR2232311B1 (en
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
SOBIO LAB
Original Assignee
SOBIO LAB
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by SOBIO LAB filed Critical SOBIO LAB
Priority to FR7320286A priority Critical patent/FR2232311A1/en
Publication of FR2232311A1 publication Critical patent/FR2232311A1/en
Application granted granted Critical
Publication of FR2232311B1 publication Critical patent/FR2232311B1/fr
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D493/00—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system
    • C07D493/02—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system in which the condensed system contains two hetero rings
    • C07D493/04—Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

Cpds. of furmula (I): (where X is CH2CHOHCH2NHCMe3 (II) or CH2CH2N(CHMe2)2 (III) have antiarythmic activity with very good general and digestive tolerance. (I: X=(II)) also has beta-lytic activity and is prepd. from a novel cpd. Pharmaceutically acceptable salts are also claimed, esp. hydrochlorides of (I: X = (II) or (III) and the mono-citrate of (I: X = IV).
FR7320286A 1973-06-05 1973-06-05 Antiarrhythmic khellin-quinol derivs. - comprising the t-butyl-amino-hydroxy-propyl and di-isopropyl-amino-ethyl ethers Granted FR2232311A1 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
FR7320286A FR2232311A1 (en) 1973-06-05 1973-06-05 Antiarrhythmic khellin-quinol derivs. - comprising the t-butyl-amino-hydroxy-propyl and di-isopropyl-amino-ethyl ethers

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR7320286A FR2232311A1 (en) 1973-06-05 1973-06-05 Antiarrhythmic khellin-quinol derivs. - comprising the t-butyl-amino-hydroxy-propyl and di-isopropyl-amino-ethyl ethers

Publications (2)

Publication Number Publication Date
FR2232311A1 true FR2232311A1 (en) 1975-01-03
FR2232311B1 FR2232311B1 (en) 1976-07-02

Family

ID=9120491

Family Applications (1)

Application Number Title Priority Date Filing Date
FR7320286A Granted FR2232311A1 (en) 1973-06-05 1973-06-05 Antiarrhythmic khellin-quinol derivs. - comprising the t-butyl-amino-hydroxy-propyl and di-isopropyl-amino-ethyl ethers

Country Status (1)

Country Link
FR (1) FR2232311A1 (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6787570B2 (en) 1999-09-23 2004-09-07 Pfizer, Inc. Substituted N-cycloalkyl-N-benzyl aminoalcohol compounds useful for inhibiting cholesteryl ester transfer protein activity

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB735729A (en) * 1952-01-24 1955-08-24 Jean Maurice Rene Alfred Delou Improvements in or relating to amino-ethers
DE1067033B (en) * 1959-10-15 Chem pharmaz Fabrik Dr Hermann Thiemann GmbH Lunen (Westf ) Process for the preparation of basic substituted monoethers of 2-methyl 5 8-dioxy-4'5 6,7-furano chromons
FR2077694A1 (en) * 1970-02-06 1971-11-05 Sobio Lab Isopropylaminopropyl ethers of khellin-quinol - as coronary vasodilat and oxygen economisers

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE1067033B (en) * 1959-10-15 Chem pharmaz Fabrik Dr Hermann Thiemann GmbH Lunen (Westf ) Process for the preparation of basic substituted monoethers of 2-methyl 5 8-dioxy-4'5 6,7-furano chromons
GB735729A (en) * 1952-01-24 1955-08-24 Jean Maurice Rene Alfred Delou Improvements in or relating to amino-ethers
FR2077694A1 (en) * 1970-02-06 1971-11-05 Sobio Lab Isopropylaminopropyl ethers of khellin-quinol - as coronary vasodilat and oxygen economisers

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6787570B2 (en) 1999-09-23 2004-09-07 Pfizer, Inc. Substituted N-cycloalkyl-N-benzyl aminoalcohol compounds useful for inhibiting cholesteryl ester transfer protein activity

Also Published As

Publication number Publication date
FR2232311B1 (en) 1976-07-02

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Legal Events

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