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FR2170862A1 - 5,00-imino-dibenzocycloheptides - with cns sedative and stimulant activity - Google Patents

5,00-imino-dibenzocycloheptides - with cns sedative and stimulant activity

Info

Publication number
FR2170862A1
FR2170862A1 FR7203779A FR7203779A FR2170862A1 FR 2170862 A1 FR2170862 A1 FR 2170862A1 FR 7203779 A FR7203779 A FR 7203779A FR 7203779 A FR7203779 A FR 7203779A FR 2170862 A1 FR2170862 A1 FR 2170862A1
Authority
FR
France
Prior art keywords
alkyl
dibenzocycloheptides
imino
stimulant activity
cpds
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
FR7203779A
Other languages
French (fr)
Other versions
FR2170862B1 (en
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sanofi Aventis France
Original Assignee
Roussel Uclaf SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Roussel Uclaf SA filed Critical Roussel Uclaf SA
Priority to FR7203779A priority Critical patent/FR2170862A1/en
Publication of FR2170862A1 publication Critical patent/FR2170862A1/en
Application granted granted Critical
Publication of FR2170862B1 publication Critical patent/FR2170862B1/fr
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D451/00—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

Cpds of formula: their racemic and optically active isomers and their acid-addition salts, where R1, R2 are H, Cl, Br alkyl(C1-6) alkoxy (C1-6), CF3 dialkyl-(C1-6)amino R3 is H, Cl, OH, NH2, acyloxy) C1-16); R4, R5 together are =O; or R4 (cis) and R5(trans)are where acyl has C1-16 and alkyl, has C1-6; R is H', alkyl (C1-6) opt. substd. by phenyl; the gps-(CH)nOH, - - (CH2)-NH- alkyl, CO2 alkyl, acyl (C1-16), where the alkyl gps have C1-6 and n is 2-5. The cpds have both CNS stimulant and sedative activity for human and veterinary medicine in treatment of metal disorders. Adult dose is 10-200 mg/day.
FR7203779A 1972-02-04 1972-02-04 5,00-imino-dibenzocycloheptides - with cns sedative and stimulant activity Granted FR2170862A1 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
FR7203779A FR2170862A1 (en) 1972-02-04 1972-02-04 5,00-imino-dibenzocycloheptides - with cns sedative and stimulant activity

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR7203779A FR2170862A1 (en) 1972-02-04 1972-02-04 5,00-imino-dibenzocycloheptides - with cns sedative and stimulant activity

Publications (2)

Publication Number Publication Date
FR2170862A1 true FR2170862A1 (en) 1973-09-21
FR2170862B1 FR2170862B1 (en) 1975-10-10

Family

ID=9093004

Family Applications (1)

Application Number Title Priority Date Filing Date
FR7203779A Granted FR2170862A1 (en) 1972-02-04 1972-02-04 5,00-imino-dibenzocycloheptides - with cns sedative and stimulant activity

Country Status (1)

Country Link
FR (1) FR2170862A1 (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2638746A1 (en) * 1988-11-09 1990-05-11 Roussel Uclaf NOVEL DERIVATIVES OF DIBENZOCYCLOHEPTENE, PROCESS FOR THE PREPARATION THEREOF AND THEIR USE AS MEDICAMENTS

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2638746A1 (en) * 1988-11-09 1990-05-11 Roussel Uclaf NOVEL DERIVATIVES OF DIBENZOCYCLOHEPTENE, PROCESS FOR THE PREPARATION THEREOF AND THEIR USE AS MEDICAMENTS
EP0368756A1 (en) * 1988-11-09 1990-05-16 Roussel-Uclaf Dibenzocycloheptene derivatives, process for their preparation and their use as medicaments

Also Published As

Publication number Publication date
FR2170862B1 (en) 1975-10-10

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Legal Events

Date Code Title Description
ST Notification of lapse