FR13C0040I1 - - Google Patents
Info
- Publication number
- FR13C0040I1 FR13C0040I1 FR13C0040C FR13C0040I1 FR 13C0040 I1 FR13C0040 I1 FR 13C0040I1 FR 13C0040 C FR13C0040 C FR 13C0040C FR 13C0040 I1 FR13C0040 I1 FR 13C0040I1
- Authority
- FR
- France
- Prior art keywords
- protein
- antigens
- nada
- subject
- antibody response
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Active
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/02—Bacterial antigens
- A61K39/095—Neisseria
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/02—Bacterial antigens
- A61K39/05—Actinobacteria, e.g. Actinomyces, Streptomyces, Nocardia, Bifidobacterium, Gardnerella, Corynebacterium; Propionibacterium
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/02—Bacterial antigens
- A61K39/08—Clostridium, e.g. Clostridium tetani
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/02—Bacterial antigens
- A61K39/09—Lactobacillales, e.g. aerococcus, enterococcus, lactobacillus, lactococcus, streptococcus
- A61K39/092—Streptococcus
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/02—Bacterial antigens
- A61K39/102—Pasteurellales, e.g. Actinobacillus, Pasteurella; Haemophilus
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
- C07K14/22—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Neisseriaceae (F)
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Mycology (AREA)
- Immunology (AREA)
- Epidemiology (AREA)
- Microbiology (AREA)
- Organic Chemistry (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
- Gastroenterology & Hepatology (AREA)
- Oncology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Communicable Diseases (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Peptides Or Proteins (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (4)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB0223741A GB0223741D0 (en) | 2002-10-11 | 2002-10-11 | Composition with five meningococcal antigens |
GB0305831A GB0305831D0 (en) | 2003-03-13 | 2003-03-13 | Broad protection meningococcal vaccines |
GB0309115A GB0309115D0 (en) | 2003-04-22 | 2003-04-22 | Broad protection meningococcal vaccines |
PCT/IB2003/004848 WO2004032958A1 (fr) | 2002-10-11 | 2003-10-02 | Vaccins polypeptidiques offrant une large protection contre des lignees de meningocoques hypervirulentes |
Publications (2)
Publication Number | Publication Date |
---|---|
FR13C0040I1 true FR13C0040I1 (fr) | 2013-08-23 |
FR13C0040I2 FR13C0040I2 (fr) | 2014-05-16 |
Family
ID=32096623
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
FR13C0040C Active FR13C0040I2 (fr) | 2002-10-11 | 2013-07-11 | Vaccins polypeptidiques offrant une large protection contre des lignees de meningocoques hypervirulentes |
Country Status (22)
Country | Link |
---|---|
US (2) | US8663656B2 (fr) |
EP (3) | EP2351579B1 (fr) |
JP (4) | JP4697706B2 (fr) |
CN (1) | CN1809380B (fr) |
AT (1) | ATE492288T1 (fr) |
AU (1) | AU2003274511B2 (fr) |
BE (1) | BE2013C042I2 (fr) |
BR (1) | BRPI0315228A8 (fr) |
CA (1) | CA2501812C (fr) |
CY (4) | CY1111341T1 (fr) |
DE (1) | DE60335477D1 (fr) |
DK (3) | DK2353608T3 (fr) |
ES (2) | ES2608048T3 (fr) |
FR (1) | FR13C0040I2 (fr) |
HU (3) | HUE047780T2 (fr) |
LU (1) | LU92241I2 (fr) |
MX (1) | MXPA05003863A (fr) |
NL (1) | NL300604I2 (fr) |
NZ (1) | NZ562998A (fr) |
PT (3) | PT2353608T (fr) |
SI (3) | SI1549338T1 (fr) |
WO (1) | WO2004032958A1 (fr) |
Families Citing this family (95)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
PT1944371E (pt) | 1998-05-01 | 2015-07-13 | Novartis Ag | Antigénios e composições da neisseria meningitidis |
US20070026021A1 (en) * | 1998-05-01 | 2007-02-01 | Chiron S.R.I. | Neisseria meningitidis antigens and compositions |
US10967045B2 (en) * | 1998-11-02 | 2021-04-06 | Secretary of State for Health and Social Care | Multicomponent meningococcal vaccine |
EP2290083B1 (fr) | 1999-04-30 | 2014-08-20 | Novartis Vaccines and Diagnostics S.r.l. | Antigènes conservés de Neisseria |
NZ515935A (en) | 1999-05-19 | 2004-01-30 | Chiron S | Combination Neisserial compositions and vaccines for the prevention of infections due to Neisseria bacteria such as meningococcal meningitis |
MXPA02004283A (es) | 1999-10-29 | 2002-10-17 | Chiron Spa | Peptidos antigenicos neisseriales. |
GB9928196D0 (en) | 1999-11-29 | 2000-01-26 | Chiron Spa | Combinations of B, C and other antigens |
PT1248647E (pt) * | 2000-01-17 | 2010-11-18 | Novartis Vaccines & Diagnostics Srl | Vacina de vesícula da membrana externa (omv) compreendendo proteínas de membrana externa de n. meningitidis do serogrupo b |
PT1947187E (pt) | 2000-02-28 | 2011-07-04 | Novartis Vaccines & Diagnostic | Expressões híbridas de proteínas de neisseria |
KR20030024811A (ko) * | 2000-07-27 | 2003-03-26 | 칠드런즈 하스피틀 앤드 리써치 센터 앳 오클랜드 | 나이세리아 메닌지티디스에 의하여 유발되는 질병에 대한광범위하게 유효한 보호를 위한 백신 |
GB0115176D0 (en) | 2001-06-20 | 2001-08-15 | Chiron Spa | Capular polysaccharide solubilisation and combination vaccines |
GB0118249D0 (en) | 2001-07-26 | 2001-09-19 | Chiron Spa | Histidine vaccines |
WO2003010194A2 (fr) | 2001-07-27 | 2003-02-06 | Chiron Srl. | Adhesines des meningocoques |
GB0121591D0 (en) | 2001-09-06 | 2001-10-24 | Chiron Spa | Hybrid and tandem expression of neisserial proteins |
MX339524B (es) | 2001-10-11 | 2016-05-30 | Wyeth Corp | Composiciones inmunogenicas novedosas para la prevencion y tratamiento de enfermedad meningococica. |
EP2572707A3 (fr) * | 2002-02-20 | 2013-11-06 | Novartis Vaccines and Diagnostics, Inc. | Microparticules avec des molécules contenant un polypeptide adsorbé |
NZ587398A (en) * | 2002-08-02 | 2012-03-30 | Glaxosmithkline Biolog Sa | Neisserial bleb preparations and vaccines comprising them |
DE60335477D1 (de) * | 2002-10-11 | 2011-02-03 | Novartis Vaccines & Diagnostic | Polypeptidimpstoffe zum breiten schutz gegen hypervirulente meningokokken-linien |
GB0227346D0 (en) * | 2002-11-22 | 2002-12-31 | Chiron Spa | 741 |
PT2172213E (pt) * | 2003-01-30 | 2013-06-03 | Novartis Ag | Vacinas injetáveis contra múltiplos serogrupos meningocócicos |
DK1670506T3 (da) | 2003-10-02 | 2013-02-25 | Novartis Ag | Flydende vacciner mod multiple meningococserogrupper |
GB0323103D0 (en) | 2003-10-02 | 2003-11-05 | Chiron Srl | De-acetylated saccharides |
AU2011224064A1 (en) * | 2003-10-02 | 2011-10-06 | Novartis Vaccines And Diagnostics S.R.L. | Liquid vaccines for multiple meningococcal serogroups |
GB0408977D0 (en) | 2004-04-22 | 2004-05-26 | Chiron Srl | Immunising against meningococcal serogroup Y using proteins |
GB0500787D0 (en) | 2005-01-14 | 2005-02-23 | Chiron Srl | Integration of meningococcal conjugate vaccination |
WO2005105140A2 (fr) | 2004-04-30 | 2005-11-10 | Chiron Srl | Integration d'une vaccination conjuguee antimeningococcique |
GB0409745D0 (en) | 2004-04-30 | 2004-06-09 | Chiron Srl | Compositions including unconjugated carrier proteins |
GB0413868D0 (en) | 2004-06-21 | 2004-07-21 | Chiron Srl | Dimensional anlaysis of saccharide conjugates |
GB0419408D0 (en) * | 2004-09-01 | 2004-10-06 | Chiron Srl | 741 chimeric polypeptides |
GB0419846D0 (en) | 2004-09-07 | 2004-10-13 | Chiron Srl | Vaccine adjuvants for saccharides |
GB0424092D0 (en) | 2004-10-29 | 2004-12-01 | Chiron Srl | Immunogenic bacterial vesicles with outer membrane proteins |
PT2682126T (pt) | 2005-01-27 | 2017-02-28 | Children`S Hospital & Res Center At Oakland | Vacinas de vesícula com base em agn1870 para proteção de amplo espetro contra doenças causadas por neisseria meningitidis |
US8758764B2 (en) | 2005-02-18 | 2014-06-24 | Novartis Vaccines And Diagnostics Srl | Proteins and nucleic acids from meningitis/sepsis-associated Escherichia coli |
MX291624B (es) | 2005-02-18 | 2011-11-04 | Novartis Vaccines & Diagnostic | Inmunogenos de escherichia coli uropatogenica. |
PT2351578T (pt) | 2005-06-27 | 2017-04-07 | Glaxosmithkline Biologicals Sa | Processo para o fabrico de vacinas |
GB0524066D0 (en) | 2005-11-25 | 2006-01-04 | Chiron Srl | 741 ii |
US20110008279A1 (en) * | 2005-12-06 | 2011-01-13 | Vega Masignani | Methods and Compositions Relating to Adhesins as Adjuvants |
EP2064230A2 (fr) | 2006-08-16 | 2009-06-03 | Novartis AG | Immunogènes pour escherichia coli uropathogène |
AR064642A1 (es) | 2006-12-22 | 2009-04-15 | Wyeth Corp | Polinucleotido vector que lo comprende celula recombinante que comprende el vector polipeptido , anticuerpo , composicion que comprende el polinucleotido , vector , celula recombinante polipeptido o anticuerpo , uso de la composicion y metodo para preparar la composicion misma y preparar una composi |
GB0700135D0 (en) * | 2007-01-04 | 2007-02-14 | Glaxosmithkline Biolog Sa | Vaccine |
GB0700562D0 (en) | 2007-01-11 | 2007-02-21 | Novartis Vaccines & Diagnostic | Modified Saccharides |
GB0713880D0 (en) | 2007-07-17 | 2007-08-29 | Novartis Ag | Conjugate purification |
WO2009038889A1 (fr) * | 2007-08-02 | 2009-03-26 | Children's Hospital And Research Center At Oakland | Vaccins vésiculaires à base de fhbp et de lpxl1 pour une protection à large spectre contre les maladies à neisseria meningitidis |
JP5701058B2 (ja) | 2007-10-19 | 2015-04-15 | ノバルティス アーゲー | 髄膜炎菌ワクチン処方物 |
WO2009104097A2 (fr) | 2008-02-21 | 2009-08-27 | Novartis Ag | Polypeptides fhbp à méningocoques |
CA2716706C (fr) | 2008-03-03 | 2014-02-18 | Irm Llc | Composes et compositions servant de modulateurs de l'activite des tlr |
WO2009150531A1 (fr) * | 2008-06-09 | 2009-12-17 | Novartis Ag | Anticorps dirigés contre la protéine de neisseria liant le facteur h |
IT1394288B1 (it) * | 2008-09-12 | 2012-06-06 | Novartis Vaccines & Diagnostic | Immunogeni di proteine che legano il fattore h. |
JP2012512240A (ja) | 2008-12-17 | 2012-05-31 | ノバルティス アーゲー | ヘモグロビン受容体を含む髄膜炎菌ワクチン |
CN102438649A (zh) | 2009-03-24 | 2012-05-02 | 诺华有限公司 | 脑膜炎球菌h因子结合蛋白和肺炎球菌结合糖的组合物 |
SI2411048T1 (sl) | 2009-03-24 | 2020-08-31 | Glaxosmithkline Biologicals Sa | Meningokokni faktor H vezavni protein uporabljen kot adjuvans |
AU2010258677B2 (en) | 2009-06-10 | 2016-10-06 | Glaxosmithkline Biologicals S.A. | Benzonaphthyridine-containing vaccines |
ES2596653T3 (es) | 2009-06-16 | 2017-01-11 | Glaxosmithkline Biologicals Sa | Ensayos bactericidas de opsonización y dependientes de anticuerpo mediado por el complemento de alto rendimiento |
JP2013502918A (ja) * | 2009-08-27 | 2013-01-31 | ノバルティス アーゲー | 髄膜炎菌fHBP配列を含むハイブリッドポリペプチド |
BR112012004276A2 (pt) | 2009-08-27 | 2017-10-24 | Novartis Ag | adjuvante compreendendo alumínio, oligonucleotídeo e policátion |
NZ598654A (en) | 2009-09-02 | 2014-05-30 | Novartis Ag | Immunogenic compositions including tlr activity modulators |
TWI445708B (zh) | 2009-09-02 | 2014-07-21 | Irm Llc | 作為tlr活性調節劑之化合物及組合物 |
CN102724988B (zh) | 2009-09-30 | 2014-09-10 | 诺华股份有限公司 | 脑膜炎球菌fHBP多肽的表达 |
BR112012010531A2 (pt) | 2009-10-27 | 2019-09-24 | Novartis Ag | "polipeptídeos de modificação meningocócica fhbp" |
WO2011057148A1 (fr) | 2009-11-05 | 2011-05-12 | Irm Llc | Composés et compositions permettant de moduler l'activité des tlr-7 |
MX339146B (es) | 2009-12-15 | 2016-05-13 | Novartis Ag | Suspension homogenea de compuestos inmunopotenciadores y usos de los mismos. |
WO2012020326A1 (fr) | 2010-03-18 | 2012-02-16 | Novartis Ag | Vaccins adjuvantés contre le méningocoque de sérogroupe b |
EP2549990A1 (fr) | 2010-03-23 | 2013-01-30 | Irm Llc | Composés (lipopeptides à base de cystéine) et compositions en tant qu'agonistes des tlr2 utilisés pour traiter des infections, inflammations, maladies respiratoires entre autres |
WO2011126863A1 (fr) | 2010-03-30 | 2011-10-13 | Children's Hospital & Research Center Oakland | Protéines de liaison du facteur h (fhbp) avec des propriétés altérées et leurs procédés d'utilisation |
KR20130121699A (ko) | 2010-05-28 | 2013-11-06 | 테트리스 온라인, 인코포레이티드 | 상호작용 혼성 비동기 컴퓨터 게임 기반구조 |
US10478483B2 (en) | 2010-06-25 | 2019-11-19 | Glaxosmithkline Biologicals Sa | Combinations of meningococcal factor H binding proteins |
TWI503411B (zh) * | 2010-08-11 | 2015-10-11 | Nat Health Research Institutes | B群腦膜炎球菌次單位疫苗之製造及純化 |
SI3246044T2 (sl) | 2010-08-23 | 2024-06-28 | Wyeth Llc | Stabilne formulacije antigenov neisseria meningitidis RLP2086 |
AU2011295853A1 (en) | 2010-09-01 | 2013-04-04 | Irm Llc | Adsorption of immunopotentiators to insoluble metal salts |
ES2744471T3 (es) | 2010-09-04 | 2020-02-25 | Glaxosmithkline Biologicals Sa | Ensayos de anticuerpos bactericidas para evaluar la inmunogenia y la potencia de vacunas de sacárido capsular meningocócico |
AU2011300418B2 (en) * | 2010-09-10 | 2016-05-12 | Glaxosmithkline Biologicals Sa | Meningococcus overexpressing NadA and/or NHBA and outer membrane vesicles derived therefrom |
GB201015132D0 (en) * | 2010-09-10 | 2010-10-27 | Univ Bristol | Vaccine composition |
CA2809758C (fr) | 2010-09-10 | 2021-07-13 | Wyeth Llc | Variants non-lipidiques des antigenes orf 2086 de neisseria meningitidis |
TR201811280T4 (tr) | 2011-03-02 | 2018-08-27 | Glaxosmithkline Biologicals Sa | Düşük antijen ve/ veya adjuvan dozları olan karma aşılar. |
RU2014140336A (ru) | 2012-03-07 | 2016-04-27 | Новартис Аг | Иммунологически полезные соли аргинина |
MX2014010417A (es) | 2012-03-08 | 2014-09-22 | Novartis Ag | Formulaciones adyuvadas de vacunas de difteria, tetanos y tos ferina (dtp) de refuerzo. |
SA115360586B1 (ar) | 2012-03-09 | 2017-04-12 | فايزر انك | تركيبات لعلاج الالتهاب السحائي البكتيري وطرق لتحضيرها |
MX359256B (es) | 2012-03-09 | 2018-09-19 | Pfizer | Composiciones de neisseria meningitidis y metodos de las mismas. |
MX357538B (es) | 2012-06-14 | 2018-07-13 | Novartis Ag | Vacunas para meningococo de serogrupo x. |
US10000545B2 (en) | 2012-07-27 | 2018-06-19 | Institut National De La Sante Et De La Recherche Medicale | CD147 as receptor for pilus-mediated adhesion of Meningococci to vascular endothelia |
BR112015005056A2 (pt) | 2012-09-06 | 2017-11-21 | Novartis Ag | vacinas de combinação com sorogrupo b meningococcus e d/t/p |
US9764027B2 (en) | 2012-09-18 | 2017-09-19 | Glaxosmithkline Biologicals Sa | Outer membrane vesicles |
EP2964665B1 (fr) | 2013-03-08 | 2018-08-01 | Pfizer Inc | Polypeptides immunogènes de fusion |
CN105431167A (zh) | 2013-08-02 | 2016-03-23 | 奥克兰儿童医院及研究中心 | 非天然发生因子h结合蛋白(fhbp)及其使用方法 |
RU2662968C2 (ru) | 2013-09-08 | 2018-07-31 | Пфайзер Инк. | Иммуногенная композиция против neisseria meningitidis (варианты) |
RS61246B1 (sr) | 2014-02-28 | 2021-01-29 | Glaxosmithkline Biologicals Sa | Modifikovani meningokokni fhbp polipeptidi |
ES2922554T3 (es) | 2014-07-23 | 2022-09-16 | Childrens Hospital & Res Center At Oakland | Variantes de proteínas de unión al factor H y métodos de uso de las mismas |
AU2016221318B2 (en) | 2015-02-19 | 2020-06-25 | Pfizer Inc. | Neisseria meningitidis compositions and methods thereof |
EP3298031B1 (fr) * | 2015-05-18 | 2020-10-21 | BiOMVis Srl | Compositions immunogènes comprenant des vesicules de membrane externe bacteriennes et leur utilisation |
IL267733B2 (en) | 2017-01-31 | 2023-10-01 | Pfizer | NEISSERIA MENINGITIDIS preparations and methods therefor |
CN108017688B (zh) * | 2017-12-01 | 2020-07-28 | 北京民海生物科技有限公司 | 一种目的蛋白的纯化方法 |
EP4119570A4 (fr) * | 2020-03-11 | 2023-10-11 | Anygen Co., Ltd. | Composition anti-diabète et anti-obésité comprenant un nouveau composé |
EP4169513A1 (fr) | 2021-10-19 | 2023-04-26 | GlaxoSmithKline Biologicals S.A. | Composition d'adjuvant comprenant des agonistes du sting |
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GB202208093D0 (en) | 2022-06-01 | 2022-07-13 | Glaxosmithkline Biologicals Sa | Immunogenic composition |
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