[go: up one dir, main page]
More Web Proxy on the site http://driver.im/

FI981097A0 - Solujen välisiä kiinnikemolekyylejä ja niiden sitoutumisligandeja - Google Patents

Solujen välisiä kiinnikemolekyylejä ja niiden sitoutumisligandeja

Info

Publication number
FI981097A0
FI981097A0 FI981097A FI981097A FI981097A0 FI 981097 A0 FI981097 A0 FI 981097A0 FI 981097 A FI981097 A FI 981097A FI 981097 A FI981097 A FI 981097A FI 981097 A0 FI981097 A0 FI 981097A0
Authority
FI
Finland
Prior art keywords
binding sites
adhesion molecule
intermolecular adhesion
intermolecular
molecule
Prior art date
Application number
FI981097A
Other languages
English (en)
Swedish (sv)
Other versions
FI981097A (fi
FI107451B (fi
Inventor
Timothy A Springer
Robert Rothlein
Steven D Marlin
Michael L Dustin
Original Assignee
Dana Farber Cancer Inst Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Publication of FI981097A0 publication Critical patent/FI981097A0/fi
Application filed by Dana Farber Cancer Inst Inc filed Critical Dana Farber Cancer Inst Inc
Publication of FI981097A publication Critical patent/FI981097A/fi
Application granted granted Critical
Publication of FI107451B publication Critical patent/FI107451B/fi

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/70503—Immunoglobulin superfamily
    • C07K14/70525—ICAM molecules, e.g. CD50, CD54, CD102
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575—Hormones
    • C07K14/655—Somatostatins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/04—Antineoplastic agents specific for metastasis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2803—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily
    • C07K16/2821—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily against ICAM molecules, e.g. CD50, CD54, CD102
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2839—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the integrin superfamily
    • C07K16/2845—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the integrin superfamily against integrin beta2-subunit-containing molecules, e.g. CD11, CD18
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
    • C07K2317/34—Identification of a linear epitope shorter than 20 amino acid residues or of a conformational epitope defined by amino acid residues
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/77—Internalization into the cell

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Immunology (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Pain & Pain Management (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Cell Biology (AREA)
  • Transplantation (AREA)
  • Rheumatology (AREA)
  • Oncology (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Endocrinology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
FI981097A 1988-09-28 1998-05-18 Menetelmä ICAM-1 (solujen välisen kiinnikemolekyylin) saamiseksi oleellisesti puhtaassa muodossa FI107451B (fi)

Applications Claiming Priority (6)

Application Number Priority Date Filing Date Title
US25044688A 1988-09-28 1988-09-28
US25044688 1988-09-28
US37388289A 1989-06-30 1989-06-30
US37388289 1989-06-30
PCT/US1989/004242 WO1990003400A1 (en) 1988-09-28 1989-09-28 Intercellular adhesion molecules, and their binding ligands
US8904242 1989-09-28

Publications (3)

Publication Number Publication Date
FI981097A0 true FI981097A0 (fi) 1989-09-28
FI981097A FI981097A (fi) 1998-05-18
FI107451B FI107451B (fi) 2001-08-15

Family

ID=26940882

Family Applications (2)

Application Number Title Priority Date Filing Date
FI902490A FI102181B1 (fi) 1988-09-28 1990-05-21 Menetelmä ICAM-1 (solujen välisen kiinnikemolekyylin) saamiseksi oleellisesti puhtaassa muodossa
FI981097A FI107451B (fi) 1988-09-28 1998-05-18 Menetelmä ICAM-1 (solujen välisen kiinnikemolekyylin) saamiseksi oleellisesti puhtaassa muodossa

Family Applications Before (1)

Application Number Title Priority Date Filing Date
FI902490A FI102181B1 (fi) 1988-09-28 1990-05-21 Menetelmä ICAM-1 (solujen välisen kiinnikemolekyylin) saamiseksi oleellisesti puhtaassa muodossa

Country Status (7)

Country Link
JP (1) JP2976381B2 (fi)
KR (1) KR900701846A (fi)
AU (2) AU4412889A (fi)
DK (1) DK175362B1 (fi)
FI (2) FI102181B1 (fi)
HU (1) HU218904B (fi)
WO (1) WO1990003400A1 (fi)

Families Citing this family (27)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6143298A (en) * 1988-09-01 2000-11-07 Bayer Corporation Soluble truncated forms of ICAM-1
ZA896668B (en) * 1988-09-01 1990-06-27 Molecular Therapeutics Inc A human rhinovirus receptor protein that inhibits virus infectivity
EP0745852B1 (en) * 1989-03-16 2002-06-26 Center For Blood Research, Inc. Use of functional derivatives of the intercellular adhesion molecule ICAM-1 in anti-viral therapy
WO1991018010A1 (en) * 1990-05-15 1991-11-28 Swinburne Limited Inhibition of viral infection using intercellular adhesion molecule-1-like peptides and/or analogues thereof
WO1991018011A1 (en) * 1990-05-15 1991-11-28 Swinburne Limited Inhibition of cell adhesion using intercellular adhesion molecule-1-like peptides and/or analogues thereof
DK162890D0 (da) * 1990-07-06 1990-07-06 Novo Nordisk As Polypeptid
US5686581A (en) * 1990-07-20 1997-11-11 Bayer Corporation Multimeric form of human rhinovirus receptor protein
US5686582A (en) * 1990-07-20 1997-11-11 Bayer Corporation Multimeric forms of human rhinovirus receptor protein
US6107461A (en) * 1990-07-20 2000-08-22 Bayer Corporation Multimeric forms of human rhinovirus receptor and fragments thereof, and method of use
US5283058A (en) 1990-08-30 1994-02-01 The General Hospital Corporation Methods for inhibiting rejection of transplanted tissue
CA2056143A1 (en) * 1990-11-28 1992-05-29 Michael S. Diamond The mac-1 binding site of icam-1
US5932214A (en) * 1994-08-11 1999-08-03 Biogen, Inc. Treatment for inflammatory bowel disease with VLA-4 blockers
US5599790A (en) 1992-06-11 1997-02-04 The Scripps Research Institute Fibrinogen γ chain polypeptide and compositions thereof
DE69331193T2 (de) * 1992-06-11 2002-04-18 The Scripps Research Institute, La Jolla Verfahren und zusammensetzungen zur verhinderung von entzündungen, die durch endothelzellen und fibrinogen ausgelöst werden
AU674556B2 (en) * 1992-10-09 1997-01-02 Center For Blood Research, Inc., The A subpopulation of MAC-1 molecules which mediate neutrophil adhesion to ICAM-1 and fibrinogen
DE4335273A1 (de) * 1993-10-15 1995-04-20 Univ Ludwigs Albert Peptide zur Tumortherapie
CA2188287A1 (en) * 1994-04-19 1995-10-26 Stephen Benedict Icam-1/lfa-1 short-chain peptides and method of using same
WO1997000956A1 (en) * 1995-06-20 1997-01-09 Trustees Of Boston University Hypoxia-responsive adhesion molecules, specific antibodies, and their uses
ES2243301T3 (es) * 1999-09-01 2005-12-01 Boehringer Ingelheim Pharmaceuticals Inc. Compuestos para tratar enfermedades auto inmunes que contienen un compuesto que inhibe la interaccion icam-lfa-1 y un compuesto que inhibe la interaccion cd40.
ATE551339T1 (de) 2003-11-05 2012-04-15 Sarcode Bioscience Inc Modulatoren der zellulären adhäsion
CN102617557A (zh) 2005-05-17 2012-08-01 萨可德生物科学公司 治疗眼病的组合物和方法
ES2830024T3 (es) 2007-10-19 2021-06-02 Novartis Ag Composiciones y métodos para el tratamiento del edema macular
US9175091B2 (en) * 2007-11-15 2015-11-03 Chugai Seiyaku Kabushiki Kaisha Monoclonal antibody capable of binding to anexelekto, and use thereof
WO2009139817A2 (en) 2008-04-15 2009-11-19 Sarcode Corporation Crystalline pharmaceutical and methods of preparation and use thereof
US8378105B2 (en) 2009-10-21 2013-02-19 Sarcode Bioscience Inc. Crystalline pharmaceutical and methods of preparation and use thereof
RU2658015C2 (ru) 2012-07-25 2018-06-19 Саркоуд Байосайенс Инк. Ингибитор ассоциированного с функцией лимфоцитов антигена-1 (lfa-1), способы его получения и его полиморф
EP3717632B1 (en) 2017-11-30 2022-10-26 F. Hoffmann-La Roche AG B-cell cultivation method

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE128727T1 (de) * 1987-05-04 1995-10-15 Dana Farber Cancer Inst Inc Interzellulare adhäsions-moleküle und deren bindungsliganden.
ATE114972T1 (de) * 1987-11-02 1994-12-15 Baylor College Medicine Verwendung von icam-1 oder ihre funktionelle derivate zur behandlung unspezifischer entzündungen.

Also Published As

Publication number Publication date
FI902490A0 (fi) 1990-05-21
HUT56120A (en) 1991-07-29
DK128990A (da) 1990-07-26
KR900701846A (ko) 1990-12-04
JP2976381B2 (ja) 1999-11-10
DK175362B1 (da) 2004-09-13
JPH03501861A (ja) 1991-04-25
FI981097A (fi) 1998-05-18
FI102181B (fi) 1998-10-30
HU218904B (hu) 2000-12-28
AU679506B2 (en) 1997-07-03
FI107451B (fi) 2001-08-15
DK128990D0 (da) 1990-05-25
WO1990003400A1 (en) 1990-04-05
HU896074D0 (en) 1990-11-28
AU6319294A (en) 1994-08-25
FI102181B1 (fi) 1998-10-30
AU4412889A (en) 1990-04-18

Similar Documents

Publication Publication Date Title
FI981097A (fi) Solujen välisiä kiinnikemolekyylejä ja niiden sitoutumisligandeja
DK120391A (da) Sekventiel peptid- og oligonukleotidsyntese under anvendelse af immunaffinitetsteknikker
DK135189D0 (da) Polymer komposition
BR8905204A (pt) Composicao colutoria
KR900009478A (ko) 방 음 재
BR8902386A (pt) Composicao polimerica
KR900701924A (ko) 겔
DE68927982D1 (de) Polymermischungen
MX163730B (es) Composicion adhesiva mejorada
MX164890B (es) Composicion de resina aglutinante extruible
FR2634778B1 (fr) Composition adhesive
BR8906787A (pt) Composicao
FI981642A0 (fi) Solujen välisiä kiinnikemolekyylejä ja niiden sitoutumisligandeja
DK134088D0 (da) Mobilt vejeanlaeg
BR8902491A (pt) Composicao
ATA215188A (de) Skibindung
DK395288D0 (da) Proteiner
NO174328C (no) Binding for tur- og langrennsski
TR26099A (tr) Islah edilmis pestisid terkip
DK445289D0 (da) Materialesammensaetning
BR8907528A (pt) Composicao crio-protetora
ATA150388A (de) Skibindung
ATA39488A (de) Skibindung
BR8900587A (pt) Composicoes
DK52590A (da) Afgivelseslukke