FI930773A - En kemisk process - Google Patents
En kemisk process Download PDFInfo
- Publication number
- FI930773A FI930773A FI930773A FI930773A FI930773A FI 930773 A FI930773 A FI 930773A FI 930773 A FI930773 A FI 930773A FI 930773 A FI930773 A FI 930773A FI 930773 A FI930773 A FI 930773A
- Authority
- FI
- Finland
- Prior art keywords
- phenyl
- chemical process
- trinor
- dihydro
- stands
- Prior art date
Links
- 238000001311 chemical methods and process Methods 0.000 title 1
- 125000000217 alkyl group Chemical group 0.000 abstract 1
- 125000001797 benzyl group Chemical group [H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])* 0.000 abstract 1
- 125000004122 cyclic group Chemical group 0.000 abstract 1
- 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 abstract 1
- 229920006395 saturated elastomer Polymers 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
- C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D307/93—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems condensed with a ring other than six-membered
- C07D307/935—Not further condensed cyclopenta [b] furans or hydrogenated cyclopenta [b] furans
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C405/00—Compounds containing a five-membered ring having two side-chains in ortho position to each other, and having oxygen atoms directly attached to the ring in ortho position to one of the side-chains, one side-chain containing, not directly attached to the ring, a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, and the other side-chain having oxygen atoms attached in gamma-position to the ring, e.g. prostaglandins ; Analogues or derivatives thereof
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
- Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Ophthalmology & Optometry (AREA)
- General Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
- Catalysts (AREA)
- Furan Compounds (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
- Physical Or Chemical Processes And Apparatus (AREA)
- Emergency Lowering Means (AREA)
Applications Claiming Priority (4)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
HU209291 | 1991-06-24 | ||
HU912092A HU212570B (en) | 1991-06-24 | 1991-06-24 | Process for producing 13,14-dihydro-15(r)-17-phenyl-18,19,20-trinor-pgf2alfa-isopropylester |
HU9200025 | 1992-06-19 | ||
PCT/HU1992/000025 WO1993000329A1 (en) | 1991-06-24 | 1992-06-19 | Chemical process |
Publications (3)
Publication Number | Publication Date |
---|---|
FI930773A true FI930773A (fi) | 1993-02-22 |
FI930773A0 FI930773A0 (fi) | 1993-02-22 |
FI104895B FI104895B (fi) | 2000-04-28 |
Family
ID=10957725
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
FI930773A FI104895B (fi) | 1991-06-24 | 1993-02-22 | Kemiallinen menetelmä |
Country Status (23)
Country | Link |
---|---|
US (1) | US5466833A (fi) |
EP (1) | EP0544899B1 (fi) |
JP (1) | JP2635213B2 (fi) |
KR (1) | KR0163022B1 (fi) |
CN (1) | CN1035764C (fi) |
AT (1) | ATE127450T1 (fi) |
AU (1) | AU656994B2 (fi) |
BG (1) | BG61261B1 (fi) |
CZ (1) | CZ287168B6 (fi) |
DE (1) | DE69204627T2 (fi) |
DK (1) | DK0544899T3 (fi) |
ES (1) | ES2078055T3 (fi) |
FI (1) | FI104895B (fi) |
GR (1) | GR3017874T3 (fi) |
HU (1) | HU212570B (fi) |
IE (1) | IE71645B1 (fi) |
IL (1) | IL102280A (fi) |
PL (1) | PL170728B1 (fi) |
RO (1) | RO117323B1 (fi) |
RU (1) | RU2099325C1 (fi) |
TW (1) | TW310321B (fi) |
UA (1) | UA39864C2 (fi) |
WO (1) | WO1993000329A1 (fi) |
Families Citing this family (23)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5510383A (en) † | 1993-08-03 | 1996-04-23 | Alcon Laboratories, Inc. | Use of cloprostenol, fluprostenol and their salts and esters to treat glaucoma and ocular hypertension |
US6294563B1 (en) | 1994-10-27 | 2001-09-25 | Allergan Sales, Inc. | Combinations of prostaglandins and brimonidine or derivatives thereof |
US6225348B1 (en) | 1998-08-20 | 2001-05-01 | Alfred W. Paulsen | Method of treating macular degeneration with a prostaglandin derivative |
IL143477A (en) | 2001-05-31 | 2009-07-20 | Finetech Pharmaceutical Ltd | Process for the preparation of 17-phenyl-18,19,20-trinor-pgf2?? and its derivatives |
IL134241A (en) * | 2000-01-27 | 2006-06-11 | Finetech Pharmaceutical Ltd | Process for the preparation of latanoprost |
GB0112699D0 (en) | 2001-05-24 | 2001-07-18 | Resolution Chemicals Ltd | Process for the preparation of prostglandins and analogues thereof |
US20110065129A1 (en) * | 2001-07-27 | 2011-03-17 | Lowe Derek B | Indane acetic acid derivatives and their use as pharmaceutical agents, intermediates, and method of preparation |
US20050119262A1 (en) * | 2003-08-21 | 2005-06-02 | Pharmacia Corporation | Method for preventing or treating an optic neuropathy with a cox-2 inhibitor and an intraocular pressure reducing agent |
ITRM20050231A1 (it) * | 2005-05-13 | 2006-11-14 | Technopharma Sa | Procedimento per la sintesi di derivati delle prostaglandine f. |
US8546114B2 (en) | 2006-01-18 | 2013-10-01 | Chirogate International Inc. | Processes for the preparation of optically active cyclopentenones and cyclopentenones prepared therefrom |
US7511168B2 (en) | 2006-01-18 | 2009-03-31 | Shih-Yi Wei | Processes and intermediates for the preparations of prostaglandins |
JP2008037782A (ja) * | 2006-08-04 | 2008-02-21 | Daiichi Fine Chemical Co Ltd | プロスタグランジン誘導体の製造方法 |
US7642370B2 (en) | 2006-08-07 | 2010-01-05 | Daiichi Fine Chemical Co., Ltd. | Method for preparing prostaglandin derivative |
IT1392492B1 (it) | 2008-12-24 | 2012-03-09 | Ind Chimica Srl | Processo per la purificazione del latanoprost, analogo sintetico della prostaglandina pgf2alfa. |
PT2523669T (pt) * | 2010-01-11 | 2017-01-31 | Inotek Pharmaceuticals Corp | Associação, conjunto ( kit ) e método de redução da pressão intraocular |
JP2013523739A (ja) | 2010-03-26 | 2013-06-17 | イノテック ファーマシューティカルズ コーポレイション | N6−シクロペンチルアデノシン(cpa)、cpa誘導体またはそれらのプロドラッグを用いてヒトにおける眼内圧を低下させる方法 |
EP2495235B1 (en) | 2011-03-04 | 2015-08-05 | Newchem S.p.A. | Process for the synthesis of prostaglandins and intermediates thereof |
CA2837261C (en) * | 2011-06-02 | 2020-12-15 | CHINOIN Zrt. | Novel processes for the preparation of prostaglandin amides |
HU231203B1 (hu) | 2011-12-21 | 2021-10-28 | CHINOIN Gyógyszer és Vegyészeti Termékek Gyára Zrt. | Új eljárás travoprost előállítására |
ES2637332T3 (es) | 2012-01-26 | 2017-10-11 | Inotek Pharmaceuticals Corporation | Polimorfos anhidros de nitrato de (2R,3S,4R,5R)-5-(6-(ciclopentilamino)-9H-purin-9-il)-3,4-dihidroxitetrahidrofuran-2-il)}metilo y procedimientos de preparación del mismo |
HU230744B1 (hu) | 2012-11-30 | 2018-01-29 | CHINOIN Gyógyszer és Vegyészeti Termékek Gyára Zrt. | Új eljárás travoprost előállítására |
CA2903114A1 (en) | 2013-03-15 | 2014-09-25 | Inotek Pharmaceuticals Corporation | Ophthalmic formulations |
HU231214B1 (hu) | 2014-03-13 | 2021-11-29 | CHINOIN Gyógyszer és Vegyészeti Termékek Gyára Zrt. | Új eljárás nagytisztaságú prosztaglandinok előállítására |
Family Cites Families (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
BE786251A (fr) * | 1971-07-14 | 1973-01-15 | Ici Ltd | Nouveaux derives du cyclopentane |
US3971826A (en) * | 1972-07-13 | 1976-07-27 | Pfizer Inc. | 15-Substituted-ω-pentanorprostaglandins |
ES2193901T1 (es) * | 1988-09-06 | 2003-11-16 | Pharmacia Ab | Derivados de prostaglandina para el tratamiento de glaucoma o hipertension ocular. |
-
1991
- 1991-06-24 HU HU912092A patent/HU212570B/hu unknown
-
1992
- 1992-06-19 RU RU9393004874A patent/RU2099325C1/ru active
- 1992-06-19 UA UA94010047A patent/UA39864C2/uk unknown
- 1992-06-19 PL PL92298127A patent/PL170728B1/pl unknown
- 1992-06-19 DK DK92915265.0T patent/DK0544899T3/da active
- 1992-06-19 DE DE69204627T patent/DE69204627T2/de not_active Expired - Lifetime
- 1992-06-19 ES ES92915265T patent/ES2078055T3/es not_active Expired - Lifetime
- 1992-06-19 RO RO93-00230A patent/RO117323B1/ro unknown
- 1992-06-19 AT AT92915265T patent/ATE127450T1/de active
- 1992-06-19 WO PCT/HU1992/000025 patent/WO1993000329A1/en active IP Right Grant
- 1992-06-19 EP EP92915265A patent/EP0544899B1/en not_active Expired - Lifetime
- 1992-06-19 AU AU22629/92A patent/AU656994B2/en not_active Expired
- 1992-06-19 KR KR1019930700530A patent/KR0163022B1/ko not_active IP Right Cessation
- 1992-06-19 JP JP5501414A patent/JP2635213B2/ja not_active Expired - Lifetime
- 1992-06-22 IL IL102280A patent/IL102280A/en not_active IP Right Cessation
- 1992-06-24 CN CN92108844A patent/CN1035764C/zh not_active Expired - Lifetime
- 1992-07-01 IE IE922026A patent/IE71645B1/en not_active IP Right Cessation
- 1992-09-23 TW TW081107537A patent/TW310321B/zh not_active IP Right Cessation
-
1993
- 1993-02-22 FI FI930773A patent/FI104895B/fi not_active IP Right Cessation
- 1993-02-23 BG BG97471A patent/BG61261B1/bg unknown
- 1993-02-24 CZ CZ1993271A patent/CZ287168B6/cs not_active IP Right Cessation
-
1994
- 1994-10-06 US US08/319,327 patent/US5466833A/en not_active Expired - Lifetime
-
1995
- 1995-10-25 GR GR950402979T patent/GR3017874T3/el unknown
Also Published As
Publication number | Publication date |
---|---|
DE69204627T2 (de) | 1996-05-02 |
BG97471A (bg) | 1994-03-24 |
WO1993000329A1 (en) | 1993-01-07 |
FI104895B (fi) | 2000-04-28 |
CZ287168B6 (en) | 2000-10-11 |
CZ27193A3 (en) | 1993-10-13 |
UA39864C2 (uk) | 2001-07-16 |
JP2635213B2 (ja) | 1997-07-30 |
BG61261B1 (en) | 1997-04-30 |
TW310321B (fi) | 1997-07-11 |
CN1035764C (zh) | 1997-09-03 |
IE922026A1 (en) | 1992-12-30 |
HUT62561A (en) | 1993-05-28 |
IE71645B1 (en) | 1997-02-26 |
US5466833A (en) | 1995-11-14 |
FI930773A0 (fi) | 1993-02-22 |
JPH06500804A (ja) | 1994-01-27 |
CN1072408A (zh) | 1993-05-26 |
DE69204627D1 (de) | 1995-10-12 |
HU912092D0 (en) | 1991-12-30 |
RU2099325C1 (ru) | 1997-12-20 |
DK0544899T3 (da) | 1995-10-23 |
GR3017874T3 (en) | 1996-01-31 |
EP0544899B1 (en) | 1995-09-06 |
HU212570B (en) | 1996-08-29 |
IL102280A (en) | 1998-02-08 |
AU656994B2 (en) | 1995-02-23 |
ES2078055T3 (es) | 1995-12-01 |
ATE127450T1 (de) | 1995-09-15 |
PL170728B1 (pl) | 1997-01-31 |
EP0544899A1 (en) | 1993-06-09 |
AU2262992A (en) | 1993-01-25 |
KR0163022B1 (ko) | 1999-01-15 |
PL298127A1 (en) | 1994-01-24 |
RO117323B1 (ro) | 2002-01-30 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
GB | Transfer or assigment of application |
Owner name: PHARMACIA & UPJOHN AKTIEBOLAG |
|
MA | Patent expired |