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FI925611A - Heterocykliska antracyklidon- och antracyklinanaloger - Google Patents

Heterocykliska antracyklidon- och antracyklinanaloger Download PDF

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Publication number
FI925611A
FI925611A FI925611A FI925611A FI925611A FI 925611 A FI925611 A FI 925611A FI 925611 A FI925611 A FI 925611A FI 925611 A FI925611 A FI 925611A FI 925611 A FI925611 A FI 925611A
Authority
FI
Finland
Prior art keywords
antracyklinanaloger
antracyklidon
heterocycliska
och
och antracyklinanaloger
Prior art date
Application number
FI925611A
Other languages
English (en)
Other versions
FI925611A0 (fi
Inventor
Giorgio Attardo
Bernard Belleau
Yao Chang Xu
Jean-Francois Lavallee
Rabindra N Rej
Original Assignee
Iaf Biochem Int
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Iaf Biochem Int filed Critical Iaf Biochem Int
Publication of FI925611A publication Critical patent/FI925611A/fi
Publication of FI925611A0 publication Critical patent/FI925611A0/fi

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Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D335/00Heterocyclic compounds containing six-membered rings having one sulfur atom as the only ring hetero atom
    • C07D335/04Heterocyclic compounds containing six-membered rings having one sulfur atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
    • C07D335/06Benzothiopyrans; Hydrogenated benzothiopyrans
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D311/00Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
    • C07D311/02Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D311/76Benzo[c]pyrans
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D311/00Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
    • C07D311/02Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D311/78Ring systems having three or more relevant rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D319/00Heterocyclic compounds containing six-membered rings having two oxygen atoms as the only ring hetero atoms
    • C07D319/041,3-Dioxanes; Hydrogenated 1,3-dioxanes
    • C07D319/061,3-Dioxanes; Hydrogenated 1,3-dioxanes not condensed with other rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D327/00Heterocyclic compounds containing rings having oxygen and sulfur atoms as the only ring hetero atoms
    • C07D327/02Heterocyclic compounds containing rings having oxygen and sulfur atoms as the only ring hetero atoms one oxygen atom and one sulfur atom
    • C07D327/06Six-membered rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D333/00Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
    • C07D333/50Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
    • C07D333/72Benzo[c]thiophenes; Hydrogenated benzo[c]thiophenes
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D335/00Heterocyclic compounds containing six-membered rings having one sulfur atom as the only ring hetero atom
    • C07D335/04Heterocyclic compounds containing six-membered rings having one sulfur atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D407/00Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00
    • C07D407/02Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings
    • C07D407/04Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/20Carbocyclic rings
    • C07H15/24Condensed ring systems having three or more rings
    • C07H15/244Anthraquinone radicals, e.g. sennosides
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/20Carbocyclic rings
    • C07H15/24Condensed ring systems having three or more rings
    • C07H15/252Naphthacene radicals, e.g. daunomycins, adriamycins
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H17/00Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H17/00Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals
    • C07H17/04Heterocyclic radicals containing only oxygen as ring hetero atoms
    • C07H17/08Hetero rings containing eight or more ring members, e.g. erythromycins

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Virology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Forms Removed On Construction Sites Or Auxiliary Members Thereof (AREA)
FI925611A 1990-06-11 1992-12-10 Heterocykliska antracyklidon- och antracyklinanaloger FI925611A0 (fi)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US53610790A 1990-06-11 1990-06-11
PCT/CA1991/000208 WO1991019725A2 (en) 1990-06-11 1991-06-10 Heterocyclic anthracyclione and anthracycline analogs

Publications (2)

Publication Number Publication Date
FI925611A true FI925611A (fi) 1992-12-10
FI925611A0 FI925611A0 (fi) 1992-12-10

Family

ID=24137175

Family Applications (1)

Application Number Title Priority Date Filing Date
FI925611A FI925611A0 (fi) 1990-06-11 1992-12-10 Heterocykliska antracyklidon- och antracyklinanaloger

Country Status (18)

Country Link
EP (1) EP0533744A1 (fi)
JP (1) JPH06504034A (fi)
CN (1) CN1058781A (fi)
AP (1) AP340A (fi)
AU (1) AU653348B2 (fi)
CA (1) CA2085120A1 (fi)
CS (1) CS178691A3 (fi)
FI (1) FI925611A0 (fi)
HU (1) HU9203720D0 (fi)
IE (1) IE911965A1 (fi)
IL (1) IL98460A0 (fi)
MA (1) MA22178A1 (fi)
NZ (1) NZ238490A (fi)
PL (1) PL297164A1 (fi)
PT (1) PT97931A (fi)
WO (1) WO1991019725A2 (fi)
YU (1) YU103391A (fi)
ZA (1) ZA914452B (fi)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5736523A (en) * 1992-11-09 1998-04-07 Biochem Pharma Inc. Antineoplastic heteronapthoquinones
US5606037A (en) * 1992-11-09 1997-02-25 Biochem Pharma Inc. Processes antineoplastic heteronaphthoquinones
AU5414094A (en) * 1992-11-09 1994-06-08 Biochem Pharma Inc. Antineoplastic heteronaphthoquinones
AU6672794A (en) * 1993-11-05 1995-05-23 Biochem Pharma Inc. Antineoplastic heteronaphthoquinones
IT1271689B (it) * 1994-08-04 1997-06-04 Menarini Farma Ind 8-fluoro-antracicline, loro processi di preparazione e composizioni farmaceutiche che le contengono
EP3841123A2 (en) 2018-08-23 2021-06-30 Seagen Inc. Anti-tigit antibodies
CN111087377B (zh) * 2020-03-19 2020-06-26 广东省微生物研究所(广东省微生物分析检测中心) 苯并异色满醌类化合物及其制备方法和应用

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS6030315B2 (ja) * 1976-06-01 1985-07-16 三井東圧化学株式会社 4−ハロゲノメチルイソクマリン誘導体の製造法
JPS52148088A (en) * 1976-06-01 1977-12-08 Richardson Merrell Inc 111aminoalkylmorphansridinee 111ols
GB2067552B (en) * 1980-01-16 1984-02-29 Erba Farmitalia Anthracyline derivatives
JPS60142976A (ja) * 1983-12-28 1985-07-29 Yoshinori Asakawa イソクマリン誘導体
CA1330560C (en) * 1986-05-21 1994-07-05 Maurits E. A. Vandewalle Di- and tetrahydroisoquinoline derivatives
JPH01238579A (ja) * 1988-03-18 1989-09-22 Yamanouchi Pharmaceut Co Ltd Y−05460m−a物質及びその製造法
JPH08112310A (ja) * 1994-10-18 1996-05-07 New Oji Paper Co Ltd 使いすておむつ

Also Published As

Publication number Publication date
JPH06504034A (ja) 1994-05-12
CA2085120A1 (en) 1991-12-12
AU8097391A (en) 1992-01-07
FI925611A0 (fi) 1992-12-10
WO1991019725A3 (en) 1992-04-30
CN1058781A (zh) 1992-02-19
HU9203720D0 (en) 1993-03-29
EP0533744A1 (en) 1993-03-31
ZA914452B (en) 1992-06-24
YU103391A (sh) 1994-04-05
NZ238490A (en) 1994-03-25
CS178691A3 (en) 1992-01-15
PL297164A1 (fi) 1992-10-05
PT97931A (pt) 1992-03-31
WO1991019725A2 (en) 1991-12-26
AU653348B2 (en) 1994-09-29
AP340A (en) 1994-05-13
IE911965A1 (en) 1991-12-18
MA22178A1 (fr) 1991-12-31
AP9100278A0 (en) 1991-07-31
IL98460A0 (en) 1992-07-15

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