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FI880064A - FORM OF FRAMSTAELLNING AV NYA N- (1H-INDOL-4-YL) DERIVATIVES. - Google Patents

FORM OF FRAMSTAELLNING AV NYA N- (1H-INDOL-4-YL) DERIVATIVES. Download PDF

Info

Publication number
FI880064A
FI880064A FI880064A FI880064A FI880064A FI 880064 A FI880064 A FI 880064A FI 880064 A FI880064 A FI 880064A FI 880064 A FI880064 A FI 880064A FI 880064 A FI880064 A FI 880064A
Authority
FI
Finland
Prior art keywords
nya
framstaellning
indol
derivatives
chlorine
Prior art date
Application number
FI880064A
Other languages
Finnish (fi)
Other versions
FI85140B (en
FI880064A0 (en
FI85140C (en
Inventor
Francois Clemence
Jacques Guillaume
Gilles Hamon
Original Assignee
Roussel Uclaf
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Roussel Uclaf filed Critical Roussel Uclaf
Publication of FI880064A0 publication Critical patent/FI880064A0/en
Publication of FI880064A publication Critical patent/FI880064A/en
Publication of FI85140B publication Critical patent/FI85140B/en
Application granted granted Critical
Publication of FI85140C publication Critical patent/FI85140C/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04—Indoles; Hydrogenated indoles
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04—Indoles; Hydrogenated indoles
    • C07D209/08—Indoles; Hydrogenated indoles with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, directly attached to carbon atoms of the hetero ring
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/06—Antiarrhythmics

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Cardiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Indole Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)

Abstract

Products of formula (I): <IMAGE> in which one of the substituents X and Y denotes alkyl (C1-C5), alkoxy (C1-C3), chlorine, bromine, iodine, nitro or amino optionally substituted by an aliphatic acyl (C2-C5) or 2 alkyls (C1-C5) and the other substituent denotes a hydrogen, it being understood that Y does not denote methoxy and X chlorine, and their addition salts with acids. The products (I) are endowed with antiarrhythmic properties and some have anticalcic properties.
FI880064A 1987-01-09 1988-01-08 Process for the Preparation of New Therapeutically Useful N- (1H-Indo 1-4-yl) Benzamide Derivatives FI85140C (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR8700151 1987-01-09
FR8700151A FR2609464B1 (en) 1987-01-09 1987-01-09 NOVEL N- (1H-INDOL 4-YL) BENZAMIDE DERIVATIVES AND THEIR SALTS, THEIR USE AS MEDICAMENTS, AND THE COMPOSITIONS CONTAINING THEM

Publications (4)

Publication Number Publication Date
FI880064A0 FI880064A0 (en) 1988-01-08
FI880064A true FI880064A (en) 1988-07-10
FI85140B FI85140B (en) 1991-11-29
FI85140C FI85140C (en) 1992-03-10

Family

ID=9346770

Family Applications (1)

Application Number Title Priority Date Filing Date
FI880064A FI85140C (en) 1987-01-09 1988-01-08 Process for the Preparation of New Therapeutically Useful N- (1H-Indo 1-4-yl) Benzamide Derivatives

Country Status (14)

Country Link
EP (1) EP0275221B1 (en)
JP (1) JPS63188664A (en)
KR (1) KR880008988A (en)
AT (1) ATE62673T1 (en)
AU (1) AU619728B2 (en)
DE (1) DE3862380D1 (en)
DK (1) DK168377B1 (en)
ES (1) ES2029033T3 (en)
FI (1) FI85140C (en)
FR (1) FR2609464B1 (en)
GR (1) GR3002185T3 (en)
HU (1) HU201910B (en)
IE (1) IE60779B1 (en)
ZA (1) ZA8837B (en)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5234942A (en) * 1984-10-19 1993-08-10 Ici Americas Inc. Heterocyclic amides and leucotriene antagonistic use thereof
DE4119611A1 (en) * 1991-06-14 1992-12-17 Bayer Ag AGENTS FOR CONTROLLING PESTS BASED ON SUBSTITUTED OXAZOLIDINONE, NEW SUBSTITUTED OXAZOLIDINONE, THEIR PRODUCTION AND USE

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4853408A (en) * 1985-04-23 1989-08-01 Roussel Uclaf 4-phenylpropyl-indoles having antiarythmic activity
FR2583047B1 (en) * 1985-06-05 1988-01-08 Roussel Uclaf PROCESS FOR THE PREPARATION OF INDOLE 4-PHENYLPROPYL DERIVATIVES AND INTERMEDIATES
FR2584713B1 (en) * 1985-07-11 1988-09-09 Roussel Uclaf NOVEL CARBOXAMIDE INDOLE DERIVATIVES, SALTS THEREOF, PROCESS AND INTERMEDIATES FOR THEIR PREPARATION, APPLICATION AS MEDICAMENTS AND COMPOSITIONS CONTAINING THEM
ATE97403T1 (en) * 1986-12-19 1993-12-15 Roussel Uclaf INDOL CARBOXAMIDE DERIVATIVES AND THEIR SALTS, PROCESSES AND INTERMEDIATE PRODUCTS FOR THE MANUFACTURE, MEDICINAL USE AND COMPOSITIONS CONTAINING THEM.

Also Published As

Publication number Publication date
FI85140B (en) 1991-11-29
FR2609464A1 (en) 1988-07-15
FI880064A0 (en) 1988-01-08
DK3288D0 (en) 1988-01-06
HUT45491A (en) 1988-07-28
AU1012988A (en) 1988-07-14
FI85140C (en) 1992-03-10
ATE62673T1 (en) 1991-05-15
ZA8837B (en) 1989-03-29
JPS63188664A (en) 1988-08-04
EP0275221A2 (en) 1988-07-20
DK168377B1 (en) 1994-03-21
AU619728B2 (en) 1992-02-06
DK3288A (en) 1988-07-10
FR2609464B1 (en) 1990-12-07
IE60779B1 (en) 1994-08-10
EP0275221B1 (en) 1991-04-17
ES2029033T3 (en) 1992-07-16
DE3862380D1 (en) 1991-05-23
IE880039L (en) 1988-07-09
HU201910B (en) 1991-01-28
KR880008988A (en) 1988-09-13
GR3002185T3 (en) 1992-12-30
EP0275221A3 (en) 1988-08-24

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Legal Events

Date Code Title Description
MM Patent lapsed
MM Patent lapsed

Owner name: ROUSSEL UCLAF SOCIETE ANONYME