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ES8407042A1 - Sulpiride derived compound - Google Patents

Sulpiride derived compound

Info

Publication number
ES8407042A1
ES8407042A1 ES516786A ES516786A ES8407042A1 ES 8407042 A1 ES8407042 A1 ES 8407042A1 ES 516786 A ES516786 A ES 516786A ES 516786 A ES516786 A ES 516786A ES 8407042 A1 ES8407042 A1 ES 8407042A1
Authority
ES
Spain
Prior art keywords
sulpiride
organic
derived compound
indomethazine
methoxy
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES516786A
Other languages
Spanish (es)
Other versions
ES516786A0 (en
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Espinos & Bofill Lab SA
Original Assignee
Espinos & Bofill Lab SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Espinos & Bofill Lab SA filed Critical Espinos & Bofill Lab SA
Priority to ES516786A priority Critical patent/ES516786A0/en
Priority to FR8315047A priority patent/FR2534254B1/en
Priority to GB08326619A priority patent/GB2129792B/en
Priority to PT77463A priority patent/PT77463B/en
Priority to JP58186071A priority patent/JPS5988463A/en
Priority to BE0/211669A priority patent/BE897948A/en
Priority to DE19833336762 priority patent/DE3336762A1/en
Publication of ES8407042A1 publication Critical patent/ES8407042A1/en
Publication of ES516786A0 publication Critical patent/ES516786A0/en
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/04—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D207/08—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon radicals, substituted by hetero atoms, attached to ring carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04—Indoles; Hydrogenated indoles
    • C07D209/10—Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
    • C07D209/18—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D209/26—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals with an acyl radical attached to the ring nitrogen atom
    • C07D209/28—1-(4-Chlorobenzoyl)-2-methyl-indolyl-3-acetic acid, substituted in position 5 by an oxygen or nitrogen atom; Esters thereof

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Rheumatology (AREA)
  • Pain & Pain Management (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Indole Compounds (AREA)
  • Pyrrole Compounds (AREA)

Abstract

A new compound derived from the sulpiride, having the formula < IMAGE > and named 1-(p-chlorobenzoyl-2-methyl-5-methoxy-3-indolyl-acetate of N-(1-ethyl-2-pirrolidinyl)methyl-2-methoxy-5-sulfamoyl benzamide with antiinflammatory properties and a process for the preparation of said compound consisting in reacting the indomethazine or an indomethazine organic or inorganic salt with sulpiride or a sulpiride organic or inorganic salt in water, water with a hydrosoluble organic solvent, an organic solvent or a mixture of organic solvents at a temperature between 20 and 80 DEG C.
ES516786A 1982-10-08 1982-10-08 PROCEDURE FOR OBTAINING A NEW DERIVATIVE OF THE SULPIRIDE. Granted ES516786A0 (en)

Priority Applications (7)

Application Number Priority Date Filing Date Title
ES516786A ES516786A0 (en) 1982-10-08 1982-10-08 PROCEDURE FOR OBTAINING A NEW DERIVATIVE OF THE SULPIRIDE.
FR8315047A FR2534254B1 (en) 1982-10-08 1983-09-22 NEW SULPIRIDE DERIVATIVE, PROCESS FOR OBTAINING SAME, AND THERAPEUTIC USE
GB08326619A GB2129792B (en) 1982-10-08 1983-10-05 Sulpiride derived compound
PT77463A PT77463B (en) 1982-10-08 1983-10-06 PROCESS FOR THE PREPARATION OF A NEW SULPIRIDE DERIVATIVE
JP58186071A JPS5988463A (en) 1982-10-08 1983-10-06 Novel compound derived from sulpiride and manufacture
BE0/211669A BE897948A (en) 1982-10-08 1983-10-07 NEW SULPIRIDE DERIVATIVE, PROCESS FOR OBTAINING SAME AND THERAPEUTIC USE
DE19833336762 DE3336762A1 (en) 1982-10-08 1983-10-10 NEW SULPIRID DERIVATIVE AND METHOD FOR THE PRODUCTION THEREOF

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
ES516786A ES516786A0 (en) 1982-10-08 1982-10-08 PROCEDURE FOR OBTAINING A NEW DERIVATIVE OF THE SULPIRIDE.

Publications (2)

Publication Number Publication Date
ES8407042A1 true ES8407042A1 (en) 1984-09-01
ES516786A0 ES516786A0 (en) 1984-09-01

Family

ID=8484830

Family Applications (1)

Application Number Title Priority Date Filing Date
ES516786A Granted ES516786A0 (en) 1982-10-08 1982-10-08 PROCEDURE FOR OBTAINING A NEW DERIVATIVE OF THE SULPIRIDE.

Country Status (7)

Country Link
JP (1) JPS5988463A (en)
BE (1) BE897948A (en)
DE (1) DE3336762A1 (en)
ES (1) ES516786A0 (en)
FR (1) FR2534254B1 (en)
GB (1) GB2129792B (en)
PT (1) PT77463B (en)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2003099293A1 (en) * 2002-05-23 2003-12-04 Danmarks Farmaceutiske Universitet Pharmacologically active salts

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AT370721B (en) * 1981-02-24 1983-04-25 Ciba Geigy Ag METHOD FOR PRODUCING NEW SALTS OF 2- (2,6-DICHLORANILINO) -PHENYLACETIC ACID, THE

Also Published As

Publication number Publication date
GB2129792B (en) 1986-02-12
PT77463A (en) 1983-11-01
PT77463B (en) 1986-02-26
GB8326619D0 (en) 1983-11-09
FR2534254A1 (en) 1984-04-13
FR2534254B1 (en) 1985-07-12
ES516786A0 (en) 1984-09-01
JPS5988463A (en) 1984-05-22
BE897948A (en) 1984-01-30
DE3336762A1 (en) 1984-04-12
GB2129792A (en) 1984-05-23

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Legal Events

Date Code Title Description
FD1A Patent lapsed

Effective date: 19970519