FI834665A0 - Imidazo(1,5-a)pyridin-derivat - Google Patents

Imidazo(1,5-a)pyridin-derivat

Info

Publication number: FI834665A0
Authority: FI; Finland
Prior art keywords: derivate; imidazo; pyridine
Prior art date: 1982-12-21

Application number

FI834665A

Other languages

English (en)

Other versions

FI834665A (fi

FI78089B (fi

FI78089C (fi

Inventor

Leslie J Browne

Original Assignee

Ciba Geigy Ag

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1982-12-21

Filing date

1983-12-19

Publication date

1983-12-19

1983-12-19 Application filed by Ciba Geigy Ag filed Critical Ciba Geigy Ag

1983-12-19 Publication of FI834665A0 publication Critical patent/FI834665A0/fi

1984-06-22 Publication of FI834665A publication Critical patent/FI834665A/fi

1989-02-28 Publication of FI78089B publication Critical patent/FI78089B/fi

1989-06-12 Application granted granted Critical

1989-06-12 Publication of FI78089C publication Critical patent/FI78089C/fi

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/24—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D213/36—Radicals substituted by singly-bound nitrogen atoms
- C07D213/40—Acylated substituent nitrogen atom
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/24—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D213/36—Radicals substituted by singly-bound nitrogen atoms
- C07D213/38—Radicals substituted by singly-bound nitrogen atoms having only hydrogen or hydrocarbon radicals attached to the substituent nitrogen atom
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/24—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D213/54—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
- C07D213/55—Acids; Esters
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/62—Oxygen or sulfur atoms
- C07D213/63—One oxygen atom
- C07D213/65—One oxygen atom attached in position 3 or 5
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/78—Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
- C07D213/84—Nitriles
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/89—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members with hetero atoms directly attached to the ring nitrogen atom
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
General Health & Medical Sciences (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Bioinformatics & Cheminformatics (AREA)
Pharmacology & Pharmacy (AREA)
Engineering & Computer Science (AREA)
Animal Behavior & Ethology (AREA)
Chemical Kinetics & Catalysis (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Cardiology (AREA)
Heart & Thoracic Surgery (AREA)
Diabetes (AREA)
Hematology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)
Pyridine Compounds (AREA)
Plural Heterocyclic Compounds (AREA)

FI834665A 1982-12-21 1983-12-19 Foerfarande foer framstaellning av terapeutiskt verkande imidazo/1,5-a/-pyridinderivat. FI78089C (fi)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US06/451,902 US4588732A (en)	1982-12-21	1982-12-21	Certain imidazo(1,5-a)pyridine derivatives and their use as thromboxane synthetase inhibitors
US45190282		1982-12-21

Publications (4)

Publication Number	Publication Date
FI834665A0 true FI834665A0 (fi)	1983-12-19
FI834665A FI834665A (fi)	1984-06-22
FI78089B FI78089B (fi)	1989-02-28
FI78089C FI78089C (fi)	1989-06-12

Family

ID=23794170

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
FI834665A FI78089C (fi)	1982-12-21	1983-12-19	Foerfarande foer framstaellning av terapeutiskt verkande imidazo/1,5-a/-pyridinderivat.

Country Status (20)

Country	Link
US (1)	US4588732A (fi)
EP (1)	EP0114573B1 (fi)
JP (1)	JPS59118785A (fi)
KR (1)	KR910000440B1 (fi)
AR (1)	AR244226A1 (fi)
AT (1)	ATE33651T1 (fi)
AU (1)	AU576484B2 (fi)
CA (1)	CA1250845A (fi)
DE (1)	DE3376324D1 (fi)
DK (1)	DK160763C (fi)
ES (1)	ES8609318A1 (fi)
FI (1)	FI78089C (fi)
GR (1)	GR81356B (fi)
IE (1)	IE56422B1 (fi)
IL (1)	IL70485A (fi)
NO (1)	NO161319C (fi)
NZ (1)	NZ206652A (fi)
PH (1)	PH23147A (fi)
PT (1)	PT77858B (fi)
ZA (1)	ZA839439B (fi)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4889861A (en) *	1982-12-21	1989-12-26	Ciba-Geigy Corp.	Substituted imidazo[1,5-a]pyridine derivatives and other substituted bicyclic derivatives and their use as aromatase inhibitors
US4617307A (en) *	1984-06-20	1986-10-14	Ciba-Geigy Corporation	Substituted imidazo[1,5-A]pyridine derivatives as aromatase inhibitors
US4728645A (en) *	1982-12-21	1988-03-01	Ciba-Geigy Corporation	Substituted imidazo[1,5-A]pyridine derivatives and other substituted bicyclic derivatives, useful as aromatase inhibitors
US5171859A (en) *	1985-06-05	1992-12-15	Schering A.G.	Certain 2-aminomethyl-3-phenyl-pyridine intermediates for certain 8-phenyl-imidazo[1,5-a]pyridines
US5026712A (en) *	1985-06-05	1991-06-25	Schering Ag	Novel imidazo[1,5-a]pyridines, useful as cardiovascular and CNS agents
US5057521A (en) *	1988-10-26	1991-10-15	Ciba-Geigy Corporation	Use of bicyclic imidazole compounds for the treatment of hyperaldosteronism
IE904346A1 (en) *	1989-12-04	1991-06-05	Searle & Co	IMIDAZO[1,2-a]PYRIDINYLALKYL COMPOUNDS FOR TREATMENT OF¹NEUROTOXIC INJURY
KR910011852A (ko) *	1989-12-04	1991-08-07	폴 디. 매튜카이티스	신경독 장해 치료용 이미다조[1,2-a]피리디닐알킬 화합물
US5716964A (en) *	1989-12-04	1998-02-10	G.D. Searle & Co.	Tetrazolyl substituted imidazo 1,2-a!pyridinylalkyl compounds for treatment of neurotoxic injury
MTP1076B (en) *	1990-01-12	1991-09-30	Ciba Geigy Ag	Hemihydrate
EP0532754A4 (en) *	1990-05-25	1994-08-24	Yamanouchi Pharma Co Ltd	Tetrahydroimidazopyridine derivative or its salt
US5468757A (en) *	1994-01-31	1995-11-21	Eli Lilly And Company	6-azaindole thromboxane synthase inhibitors
CN100447142C (zh) *	2002-11-18	2008-12-31	诺瓦提斯公司	咪唑并[1,5a]吡啶衍生物及治疗醛固酮所介导疾病的方法

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
JPS5124517B1 (fi) *	1971-03-15	1976-07-24
JPS6050190B2 (ja) *	1978-05-02	1985-11-07	小野薬品工業株式会社	イミダゾ−ル誘導体
GB2016452B (en) *	1978-02-18	1982-07-21	Kissei Pharmaceutical	Imidazole compounds
JPS55313A (en) *	1978-06-13	1980-01-05	Kissei Pharmaceut Co Ltd	Imidazole derivative
DK471479A (da) *	1978-12-13	1980-06-14	Pfizer	Fremgangsmaade til fremstilling af imidazolderivater og salte deraf
FR2449689A1 (fr) *	1979-02-20	1980-09-19	Logeais Labor Jacques	Nouveaux derives condenses de pyrrolidine ou de piperidine, leur procede de preparation et leurs applications en therapeutique
US4444775A (en) *	1981-06-22	1984-04-24	Ciba-Geigy Corporation	Substituted imidazo[1,5-A]pyridines
CA1250844A (en) *	1981-06-22	1989-03-07	Neville Ford	Substituted imidazo¬1,5-a\|pyridines, process for their manufacture, pharmaceutical preparations containing these compounds and their therapeutic application
US4361567A (en) *	1981-10-05	1982-11-30	Schering Corporation	Treatment of peptic ulcer disease
US4409226A (en) *	1981-10-05	1983-10-11	Schering Corporation	Imidazo[1,5-a]pyridines
US4470986A (en) *	1982-12-21	1984-09-11	Ciba-Geigy Corporation	Certain imidazo (1,5-A) pyridine aliphatic carboxylic acid derivatives and their use as selective thromboxane inhibitors

1982
- 1982-12-21 US US06/451,902 patent/US4588732A/en not_active Expired - Lifetime
1983
- 1983-12-15 AT AT83810596T patent/ATE33651T1/de not_active IP Right Cessation
- 1983-12-15 DE DE8383810596T patent/DE3376324D1/de not_active Expired
- 1983-12-15 EP EP83810596A patent/EP0114573B1/de not_active Expired
- 1983-12-16 PH PH29990A patent/PH23147A/en unknown
- 1983-12-19 FI FI834665A patent/FI78089C/fi not_active IP Right Cessation
- 1983-12-19 CA CA000443590A patent/CA1250845A/en not_active Expired
- 1983-12-19 ES ES528181A patent/ES8609318A1/es not_active Expired
- 1983-12-19 IL IL70485A patent/IL70485A/xx not_active IP Right Cessation
- 1983-12-20 DK DK586483A patent/DK160763C/da not_active IP Right Cessation
- 1983-12-20 AU AU22703/83A patent/AU576484B2/en not_active Ceased
- 1983-12-20 KR KR1019830006030A patent/KR910000440B1/ko not_active IP Right Cessation
- 1983-12-20 NZ NZ206652A patent/NZ206652A/en unknown
- 1983-12-20 IE IE3008/83A patent/IE56422B1/en not_active IP Right Cessation
- 1983-12-20 GR GR73303A patent/GR81356B/el unknown
- 1983-12-20 NO NO834711A patent/NO161319C/no not_active IP Right Cessation
- 1983-12-20 PT PT77858A patent/PT77858B/pt unknown
- 1983-12-20 ZA ZA839439A patent/ZA839439B/xx unknown
- 1983-12-21 JP JP58240012A patent/JPS59118785A/ja active Granted
- 1983-12-21 AR AR83295197A patent/AR244226A1/es active

Also Published As

Publication number	Publication date
NO834711L (no)	1984-06-22
NO161319C (no)	1989-08-02
CA1250845A (en)	1989-03-07
ES528181A0 (es)	1986-09-01
FI834665A (fi)	1984-06-22
GR81356B (fi)	1984-12-11
IE56422B1 (en)	1991-07-31
FI78089B (fi)	1989-02-28
DK586483D0 (da)	1983-12-20
IL70485A (en)	1987-02-27
DE3376324D1 (de)	1988-05-26
PT77858B (en)	1986-05-08
JPS59118785A (ja)	1984-07-09
ZA839439B (en)	1984-07-25
JPH047348B2 (fi)	1992-02-10
ES8609318A1 (es)	1986-09-01
US4588732A (en)	1986-05-13
PH23147A (en)	1989-05-11
EP0114573B1 (de)	1988-04-20
FI78089C (fi)	1989-06-12
DK160763B (da)	1991-04-15
IE833008L (en)	1984-06-21
PT77858A (en)	1984-01-01
DK586483A (da)	1984-06-22
AU576484B2 (en)	1988-09-01
ATE33651T1 (de)	1988-05-15
AR244226A1 (es)	1993-10-29
NZ206652A (en)	1986-11-12
NO161319B (no)	1989-04-24
AU2270383A (en)	1984-06-28
KR840007001A (ko)	1984-12-04
DK160763C (da)	1991-09-30
KR910000440B1 (ko)	1991-01-25
EP0114573A1 (de)	1984-08-01
IL70485A0 (en)	1984-03-30

Publication	Publication Date	Title
FI831437L (fi)	1983-11-04	2-fenyl-imidazo/4,5-c/pyridiner
FI834665A0 (fi)	1983-12-19	Imidazo(1,5-a)pyridin-derivat
FI834664A0 (fi)	1983-12-19	Substituerade imidazo(1,5-a)pyridiner
FI821035A0 (fi)	1982-03-24	Imidazo/1,2-a/pyrimidinderivat, deras framstaellning och anvaendning vid sjukvaord
FI833055A0 (fi)	1983-08-26	Framstaellningsfoerfarande foer nya imidazo/1,2-a/pyrimidiner
FI853027L (fi)	1986-02-08	Imidazo/1,2-a/kinoliner, deras framstaellning och deras terapeutiska tillaempning.
DE3373473D1 (de)	1987-10-15	Pyrido(2,1-b)quinazoline derivatives
ZA835684B (en)	1985-03-27	Imidazo(1,2-a)pyrimidines
ZA837691B (en)	1985-05-29	(1,2,4)triazolo(4,3-a)quinoxaline-4-amine derivatives
IT1172389B (it)	1987-06-18	2,2,2-trialogeno-1-(trialogenometil)etiliden-bis-benzen-tioli
FI813757L (fi)	1982-05-27	Nytt foerfarande foer framstaellning av imidazo/4,5-b/pyridiner och -pyrimidiner
FI843282A0 (fi)	1984-08-20	Foerbaettringar i och beroerande pyrimido /4,5-g/kinoliner och mellanprodukter.
DD230750A1 (de)	1985-12-11	Mehrzweck-kaefigbatterie
GB8306905D0 (en)	1983-04-20	Substituted 1h-pyrazolo(1,5-a)pyrimidines
DE3368262D1 (de)	1987-01-22	Aminopyrazole compounds
IL78159A0 (en)	1986-07-31	5-aroyl-6-alkylthio-,-alkylsulfinyl-and-alkylsulfonyl-1,2-dihydro-3h-pyrrolo(1,2-a)pyrrole-1-carbonitriles
JPS56167686A (en)	1981-12-23	Pyrazolo(1,2-a)(1,2,4)benzotriazines
FI882150A0 (fi)	1988-05-06	Foerfarande foer framstaellning av pyrrolo /1,2-a/ -imidatzol- och imidatzo /1,2-a/ pyridinimmuno-modulatorer.
NO850833L (no)	1986-09-02	6-substituerte-5-fenyltetrazolo(1,5-a)(1,2,4)-triazolo(1,5
ATE28199T1 (de)	1987-07-15	Pyrrolo(3,4-d)(2)benzazepin-derivate.
FI834549A0 (fi)	1983-12-12	Pyrazolo /4,3-b//1,4/oxaziner, foerfarande foer deras framstaellning och deras anvaendning som laekemedel
IT8260506V0 (it)	1982-10-29	Letto polifunzionale.
DOP1983004103A (es)	1988-05-28	NUEVAS IMIDAZO /1,2-a/ PIRIDINAS Y PIRAZINAS
FI904878A0 (fi)	1990-10-03	Foerfarande foer framstaellning av saosom bensodiazepinreceptoragonister/antagonister anvaendbara 2-aryl- tetrahydro(pyrido- och pyrrolo) e 1,2,4 triazolo 1,5-c pyrimidoner.
NO922964L (no)	1984-04-24	Fremgangsmaate for fremstilling av muteiner

Legal Events

Date	Code	Title	Description
1997-08-26	PC	Transfer of assignment of patent	Owner name: NOVARTIS AG
2004-08-31	MM	Patent lapsed	Owner name: NOVARTIS AG