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FI843282A0 - Foerbaettringar i och beroerande pyrimido /4,5-g/kinoliner och mellanprodukter. - Google Patents

Foerbaettringar i och beroerande pyrimido /4,5-g/kinoliner och mellanprodukter.

Info

Publication number
FI843282A0
FI843282A0 FI843282A FI843282A FI843282A0 FI 843282 A0 FI843282 A0 FI 843282A0 FI 843282 A FI843282 A FI 843282A FI 843282 A FI843282 A FI 843282A FI 843282 A0 FI843282 A0 FI 843282A0
Authority
FI
Finland
Prior art keywords
och
kinoliner
beroerande
foerbaettringar
pyrimido
Prior art date
Application number
FI843282A
Other languages
English (en)
Other versions
FI78091B (fi
FI78091C (fi
FI843282A (fi
Inventor
Cynthia Lynn Nichols
Edmund Carl Kornfeld
Mark Mortensen Foreman
John Mehnert Schaus
Diane Lynn Huser
Richard Nolan Booher
Dabid Taiwai Wong
Original Assignee
Lilly Co Eli
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US06/535,503 external-priority patent/US4501890A/en
Priority claimed from US06/535,474 external-priority patent/US4521421A/en
Priority claimed from US06/575,126 external-priority patent/US4528290A/en
Application filed by Lilly Co Eli filed Critical Lilly Co Eli
Publication of FI843282A0 publication Critical patent/FI843282A0/fi
Publication of FI843282A publication Critical patent/FI843282A/fi
Priority to FI882658A priority Critical patent/FI80679C/fi
Publication of FI78091B publication Critical patent/FI78091B/fi
Application granted granted Critical
Publication of FI78091C publication Critical patent/FI78091C/fi

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D471/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04Ortho-condensed systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/20Hypnotics; Sedatives
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/24Antidepressants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/26Psychostimulants, e.g. nicotine, cocaine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00Drugs for disorders of the endocrine system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/12Antihypertensives
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D215/00Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/16Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D215/20Oxygen atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D495/00Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
    • C07D495/02Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D495/10Spiro-condensed systems

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Psychiatry (AREA)
  • Endocrinology (AREA)
  • Diabetes (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Pain & Pain Management (AREA)
  • Anesthesiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
FI843282A 1983-09-26 1984-08-20 Analogifoerfarande foer framstaellning av saosom dopaminoagonister anvaendbara pyrimido/4,5-g/kinolinderivat. FI78091C (fi)

Priority Applications (1)

Application Number Priority Date Filing Date Title
FI882658A FI80679C (fi) 1983-09-26 1988-06-06 Trans-( )-1-(alkyl eller allyl)-6-oxo- 7-alkoxikarbonyldekahydrokinoliner som aer anvaendbara som mellanprodukter vid framstaellning av som dopaminagonister anvaendbara pyrimido/4,5-g/ kinoliner.

Applications Claiming Priority (10)

Application Number Priority Date Filing Date Title
US53551983A 1983-09-26 1983-09-26
US06/535,503 US4501890A (en) 1983-09-26 1983-09-26 Trans-(±)-2,4,6-substituted-5,5a,6,7,8,9,9a,10-octahydro-pyrimido[4,5-g]quinolines
US53550383 1983-09-26
US53551983 1983-09-26
US53547483 1983-09-26
US06/535,474 US4521421A (en) 1983-09-26 1983-09-26 Treatment of sexual dysfunction
US06/575,126 US4528290A (en) 1984-01-30 1984-01-30 Stimulating dopamine D-1 receptors
US57512684 1984-01-30
US60609184A 1984-05-02 1984-05-02
US60609184 1984-05-02

Publications (4)

Publication Number Publication Date
FI843282A0 true FI843282A0 (fi) 1984-08-20
FI843282A FI843282A (fi) 1985-03-27
FI78091B FI78091B (fi) 1989-02-28
FI78091C FI78091C (fi) 1989-06-12

Family

ID=27541855

Family Applications (1)

Application Number Title Priority Date Filing Date
FI843282A FI78091C (fi) 1983-09-26 1984-08-20 Analogifoerfarande foer framstaellning av saosom dopaminoagonister anvaendbara pyrimido/4,5-g/kinolinderivat.

Country Status (16)

Country Link
EP (1) EP0139393B1 (fi)
JP (1) JPH01151581A (fi)
AU (2) AU569539B2 (fi)
CY (1) CY1495A (fi)
DE (1) DE3484583D1 (fi)
DK (4) DK164867C (fi)
FI (1) FI78091C (fi)
GB (1) GB2146985B (fi)
GR (1) GR80201B (fi)
HK (1) HK98789A (fi)
IE (1) IE57848B1 (fi)
IL (1) IL72730A (fi)
NZ (1) NZ209295A (fi)
PT (1) PT79112B (fi)
RO (1) RO89126A (fi)
SG (1) SG46389G (fi)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
HUT40656A (en) * 1984-08-03 1987-01-28 Lilly Co Eli Process for producing tricyclic quinoline derivatives
US4764609A (en) * 1986-03-31 1988-08-16 Eli Lilly And Company Synthesis of 2-aminopyrimido[4,5-g]quinolines
US4826986A (en) * 1986-06-16 1989-05-02 Eli Lilly And Company 6-Oxo-trans-octa- and decahydroquinolines
US4762843A (en) * 1986-09-15 1988-08-09 Warner-Lambert Company Hetero [f] fused carbocyclic pyridines as dopaminergic agents

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4198415A (en) * 1979-01-22 1980-04-15 Eli Lilly And Company Prolactin inhibiting octahydro pyrazolo[3,4-g]quinolines
JPS59202892A (ja) * 1983-05-04 1984-11-16 Ricoh Co Ltd 光学的情報記録媒体
US4507478A (en) * 1983-09-26 1985-03-26 Eli Lilly And Company 2-Mercaptopyrimidohexahydroquinolines and related compounds
HUT40656A (en) * 1984-08-03 1987-01-28 Lilly Co Eli Process for producing tricyclic quinoline derivatives

Also Published As

Publication number Publication date
JPH01151581A (ja) 1989-06-14
IL72730A0 (en) 1984-11-30
JPH0529398B2 (fi) 1993-04-30
DK164867B (da) 1992-08-31
DK400984A (da) 1985-03-27
AU3228084A (en) 1985-04-04
IE57848B1 (en) 1993-04-21
DK296290A (da) 1990-12-13
EP0139393A2 (en) 1985-05-02
FI78091B (fi) 1989-02-28
DK169622B1 (da) 1994-12-27
DK296390A (da) 1990-12-13
IE842154L (en) 1985-03-26
FI78091C (fi) 1989-06-12
IL72730A (en) 1987-10-30
PT79112B (en) 1986-11-14
AU585473B2 (en) 1989-06-15
NZ209295A (en) 1987-05-29
DK169948B1 (da) 1995-04-10
DK296190D0 (da) 1990-12-13
EP0139393A3 (en) 1988-01-13
PT79112A (en) 1984-09-01
DK296390D0 (da) 1990-12-13
GB2146985A (en) 1985-05-01
DE3484583D1 (de) 1991-06-20
AU8216887A (en) 1988-03-31
GR80201B (en) 1985-01-02
RO89126A (ro) 1986-04-30
DK296190A (da) 1990-12-13
GB2146985B (en) 1987-05-28
GB8421160D0 (en) 1984-09-26
HK98789A (en) 1989-12-22
DK400984D0 (da) 1984-08-22
AU569539B2 (en) 1988-02-04
DK169970B1 (da) 1995-04-18
DK296290D0 (da) 1990-12-13
CY1495A (en) 1990-02-16
EP0139393B1 (en) 1991-05-15
SG46389G (en) 1989-12-22
DK164867C (da) 1993-11-08
FI843282A (fi) 1985-03-27

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Legal Events

Date Code Title Description
MM Patent lapsed

Owner name: ELI LILLY AND COMPANY