FI102181B1 - Förfarande för att erhålla ICAM-1 (intermolekulära adhesionsmolekyler) i väsentligen ren form - Google Patents

Förfarande för att erhålla ICAM-1 (intermolekulära adhesionsmolekyler) i väsentligen ren form

Info

Publication number: FI102181B1
Authority: FI; Finland
Prior art keywords: icam; obtaining; substantially pure; pure form; adhesion molecules
Prior art date: 1988-09-28

Application number

FI902490A

Other languages

English (en)

Finnish (fi)

Other versions

FI902490A0 (fi

FI102181B (sv

Inventor

Timothy A Springer

Robert Rothlein

Steven D Marlin

Michael L Dustin

Original Assignee

Dana Farber Cancer Inst Inc

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1988-09-28

Filing date

1990-05-21

Publication date

1998-10-30

1990-05-21 Application filed by Dana Farber Cancer Inst Inc filed Critical Dana Farber Cancer Inst Inc

1990-05-21 Publication of FI902490A0 publication Critical patent/FI902490A0/fi

1998-10-30 Application granted granted Critical

1998-10-30 Publication of FI102181B1 publication Critical patent/FI102181B1/sv

1998-10-30 Publication of FI102181B publication Critical patent/FI102181B/sv

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/575—Hormones
- C07K14/655—Somatostatins
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
- C07K14/70503—Immunoglobulin superfamily
- C07K14/70525—ICAM molecules, e.g. CD50, CD54, CD102
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/04—Antineoplastic agents specific for metastasis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/2803—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily
- C07K16/2821—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily against ICAM molecules, e.g. CD50, CD54, CD102
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/2839—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the integrin superfamily
- C07K16/2845—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the integrin superfamily against integrin beta2-subunit-containing molecules, e.g. CD11, CD18
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
- C07K2317/34—Identification of a linear epitope shorter than 20 amino acid residues or of a conformational epitope defined by amino acid residues
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
- C07K2317/77—Internalization into the cell

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Life Sciences & Earth Sciences (AREA)
Immunology (AREA)
General Health & Medical Sciences (AREA)
Medicinal Chemistry (AREA)
Animal Behavior & Ethology (AREA)
Chemical Kinetics & Catalysis (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Pharmacology & Pharmacy (AREA)
General Chemical & Material Sciences (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Biochemistry (AREA)
Molecular Biology (AREA)
Genetics & Genomics (AREA)
Biophysics (AREA)
Bioinformatics & Cheminformatics (AREA)
Engineering & Computer Science (AREA)
Pain & Pain Management (AREA)
Gastroenterology & Hepatology (AREA)
Zoology (AREA)
Toxicology (AREA)
Cell Biology (AREA)
Transplantation (AREA)
Oncology (AREA)
Biomedical Technology (AREA)
Neurology (AREA)
Neurosurgery (AREA)
Rheumatology (AREA)
Endocrinology (AREA)
Peptides Or Proteins (AREA)
Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Preparation Of Compounds By Using Micro-Organisms (AREA)
Micro-Organisms Or Cultivation Processes Thereof (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

FI902490A 1988-09-28 1990-05-21 Förfarande för att erhålla ICAM-1 (intermolekulära adhesionsmolekyler) i väsentligen ren form FI102181B (sv)

Applications Claiming Priority (6)

Application Number	Priority Date	Filing Date	Title
US25044688A	1988-09-28	1988-09-28
US25044688		1988-09-28
US37388289A	1989-06-30	1989-06-30
US37388289		1989-06-30
US8904242		1989-09-28
PCT/US1989/004242 WO1990003400A1 (en)	1988-09-28	1989-09-28	Intercellular adhesion molecules, and their binding ligands

Publications (3)

Publication Number	Publication Date
FI902490A0 FI902490A0 (fi)	1990-05-21
FI102181B1 true FI102181B1 (sv)	1998-10-30
FI102181B FI102181B (sv)	1998-10-30

Family

ID=26940882

Family Applications (2)

Application Number	Title	Priority Date	Filing Date
FI902490A FI102181B (sv)	1988-09-28	1990-05-21	Förfarande för att erhålla ICAM-1 (intermolekulära adhesionsmolekyler) i väsentligen ren form
FI981097A FI107451B (sv)	1988-09-28	1998-05-18	Förfarande för att erhålla ICAM-1 (intermolekulära adhesionsmolekyler) i väsentligen ren form

Family Applications After (1)

Application Number	Title	Priority Date	Filing Date
FI981097A FI107451B (sv)	1988-09-28	1998-05-18	Förfarande för att erhålla ICAM-1 (intermolekulära adhesionsmolekyler) i väsentligen ren form

Country Status (7)

Country	Link
JP (1)	JP2976381B2 (sv)
KR (1)	KR900701846A (sv)
AU (2)	AU4412889A (sv)
DK (1)	DK175362B1 (sv)
FI (2)	FI102181B (sv)
HU (1)	HU218904B (sv)
WO (1)	WO1990003400A1 (sv)

Families Citing this family (27)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US6143298A (en) *	1988-09-01	2000-11-07	Bayer Corporation	Soluble truncated forms of ICAM-1
ZA896668B (en) *	1988-09-01	1990-06-27	Molecular Therapeutics Inc	A human rhinovirus receptor protein that inhibits virus infectivity
ES2097748T3 (es) *	1989-03-16	1997-04-16	Blood Res Center	Uso de derivados funcionales de la molecula de adhesion intercelular icam-1 en la terapia antivirica.
WO1991018011A1 (en) *	1990-05-15	1991-11-28	Swinburne Limited	Inhibition of cell adhesion using intercellular adhesion molecule-1-like peptides and/or analogues thereof
WO1991018010A1 (en) *	1990-05-15	1991-11-28	Swinburne Limited	Inhibition of viral infection using intercellular adhesion molecule-1-like peptides and/or analogues thereof
DK162890D0 (da) *	1990-07-06	1990-07-06	Novo Nordisk As	Polypeptid
US6107461A (en) *	1990-07-20	2000-08-22	Bayer Corporation	Multimeric forms of human rhinovirus receptor and fragments thereof, and method of use
US5674982A (en) *	1990-07-20	1997-10-07	Bayer Corporation	Multimeric form of human rhinovirus receptor protein
US5686582A (en) *	1990-07-20	1997-11-11	Bayer Corporation	Multimeric forms of human rhinovirus receptor protein
US5283058A (en)	1990-08-30	1994-02-01	The General Hospital Corporation	Methods for inhibiting rejection of transplanted tissue
CA2056143A1 (en) *	1990-11-28	1992-05-29	Michael S. Diamond	The mac-1 binding site of icam-1
US5932214A (en)	1994-08-11	1999-08-03	Biogen, Inc.	Treatment for inflammatory bowel disease with VLA-4 blockers
EP0644768B1 (en) *	1992-06-11	2001-11-21	The Scripps Research Institute	Methods and compositions for inhibiting endothelial cell and fibrinogen mediated inflammation
US5599790A (en)	1992-06-11	1997-02-04	The Scripps Research Institute	Fibrinogen γ chain polypeptide and compositions thereof
CA2144738A1 (en) *	1992-10-09	1994-04-28	Michael Diamond	A subpopulation of mac-1 (cd11b/cd18) molecules which mediate neutrophil adhesion to icam-1 and fibrinogen
DE4335273A1 (de) *	1993-10-15	1995-04-20	Univ Ludwigs Albert	Peptide zur Tumortherapie
JPH09512021A (ja) *	1994-04-19	1997-12-02	ザユニバーシティオブカンサス	Ｉｃａｍ−１／ｌｆａ−１短鎖ペプチドおよび該ペプチドの使用方法
AU6390696A (en) *	1995-06-20	1997-01-22	Trustees Of Boston University	Hypoxia-responsive adhesion molecules, specific antibodies, nd their uses
ES2243301T3 (es) *	1999-09-01	2005-12-01	Boehringer Ingelheim Pharmaceuticals Inc.	Compuestos para tratar enfermedades auto inmunes que contienen un compuesto que inhibe la interaccion icam-lfa-1 y un compuesto que inhibe la interaccion cd40.
CA2544678C (en)	2003-11-05	2013-12-31	Sunesis Pharmaceuticals, Inc.	Modulators of cellular adhesion
CA2609053C (en)	2005-05-17	2017-04-25	Sarcode Corporation	Compositions and methods for treatment of eye disorders
CA2958665C (en)	2007-10-19	2021-03-02	Sarcode Bioscience Inc.	Compositions and methods for treatment of diabetic retinopathy
AU2008321835B2 (en) *	2007-11-15	2014-11-20	Chugai Seiyaku Kabushiki Kaisha	Monoclonal antibody capable of binding to anexelekto, and use thereof
WO2009139817A2 (en)	2008-04-15	2009-11-19	Sarcode Corporation	Crystalline pharmaceutical and methods of preparation and use thereof
US8378105B2 (en)	2009-10-21	2013-02-19	Sarcode Bioscience Inc.	Crystalline pharmaceutical and methods of preparation and use thereof
EP4406950A2 (en)	2012-07-25	2024-07-31	Bausch + Lomb Ireland Limited	Lfa-1 inhibitor and polymorph thereof
EP3717632B1 (en)	2017-11-30	2022-10-26	F. Hoffmann-La Roche AG	B-cell cultivation method

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
DE3854536T2 (de) *	1987-05-04	1996-03-07	Dana Farber Cancer Inst Inc	Interzellulare Adhäsions-Moleküle und deren Bindungsliganden.
ES2064327T3 (es) *	1987-11-02	1995-02-01	Baylor College Medicine	Uso de icam-1 o de sus derivados funcionales para el tratamiento de una inflamacion no especifica.

1989
- 1989-09-28 JP JP1510885A patent/JP2976381B2/ja not_active Expired - Lifetime
- 1989-09-28 AU AU44128/89A patent/AU4412889A/en not_active Abandoned
- 1989-09-28 KR KR1019900701105A patent/KR900701846A/ko not_active IP Right Cessation
- 1989-09-28 HU HU074/89A patent/HU218904B/hu unknown
- 1989-09-28 WO PCT/US1989/004242 patent/WO1990003400A1/en active IP Right Grant
1990
- 1990-05-21 FI FI902490A patent/FI102181B/sv active IP Right Grant
- 1990-05-25 DK DK199001289A patent/DK175362B1/da not_active IP Right Cessation
1994
- 1994-05-19 AU AU63192/94A patent/AU679506B2/en not_active Expired
1998
- 1998-05-18 FI FI981097A patent/FI107451B/sv active

Also Published As

Publication number	Publication date
FI981097A0 (sv)	1989-09-28
FI981097A (sv)	1998-05-18
FI902490A0 (fi)	1990-05-21
KR900701846A (ko)	1990-12-04
AU679506B2 (en)	1997-07-03
AU4412889A (en)	1990-04-18
DK175362B1 (da)	2004-09-13
HU218904B (hu)	2000-12-28
WO1990003400A1 (en)	1990-04-05
JP2976381B2 (ja)	1999-11-10
DK128990A (da)	1990-07-26
DK128990D0 (da)	1990-05-25
JPH03501861A (ja)	1991-04-25
AU6319294A (en)	1994-08-25
HUT56120A (en)	1991-07-29
HU896074D0 (en)	1990-11-28
FI102181B (sv)	1998-10-30
FI107451B (sv)	2001-08-15

Publication	Publication Date	Title
FI102181B1 (sv)	1998-10-30	Förfarande för att erhålla ICAM-1 (intermolekulära adhesionsmolekyler) i väsentligen ren form
GB8803574D0 (en)	1988-03-16	Improvements in/relating to stretch films
IT1201075B (it)	1989-01-27	Metodo e apparato per il posizionamento di articoli in stoffa
AT383606B (de)	1987-07-27	Verfahren zur herstellung von neuen transparenten copolyamiden mischungen daraus, und deren verwendung zur herstellung von formkoerpern
NO180198C (no)	1997-03-05	Peptidsyntese-fremgangsmåte og fast bærer for anvendelse i fremgangsmåten
DE68917625D1 (de)	1994-09-29	Verbundmaterial und Verfahren zu dessen Herstellung.
AU586391B2 (en)	1989-07-06	Apparatus for gauge distribution in plastic tubing
NO902454D0 (no)	1990-06-01	Moensterkort for montering i det bakre plan av en kortramme
DK36289D0 (da)	1989-01-27	Fremgangsmaade og apparat til gennemfoerelse af arbejdsoperationer i roer
FI895562A0 (sv)	1989-11-22	Förfarande för tillverkning av (S)- -etyl-2-oxo-1-pyrrolidinacetamid
FI894005A0 (sv)	1989-08-25	Förfarande för koncentrering av lösningar
EP0338575A3 (en)	1990-05-23	Birefringent transparent film and process for producing the same
DE69005561D1 (de)	1994-02-10	Keramikplatte mit eingelegtem Ornament und Verfahren zu deren Herstellung.
IS3725A7 (is)	1991-12-29	Amínósýruafleiður og aðferð til framleiðslu þeirra
YU124289A (en)	1990-10-31	Process for obtaining alumoxane in waterless solution
ATE83466T1 (de)	1993-01-15	Verfahren und vorrichtung zum herstellen von bildpostkarten.
GR900300096T1 (en)	1991-09-27	Adhesive for plastics, and process for using this adhesive
ATA265584A (de)	1988-07-15	Verfahren und vorrichtung zur herstellung von in zwei richtungen orientierten, waermeschrumpfenden schlauchfolien
DK110987A (da)	1987-09-11	Fremgangsmaade og apparat til paavirkning af udgangsproduktet ved findeling i valsemoeller
GB2222994B (en)	1992-06-10	Improvements in or relating to conveying apparatus
DE68914263D1 (de)	1994-05-05	Vorrichtung zum herstellen von riefen in reifen.
DE3675631D1 (de)	1990-12-20	In-vitro-kulturverfahren.
FR2633614B1 (fr)	1991-06-07	Procede de monohalogenation en (alpha) des groupements carbonyles des cetones
NO933877D0 (no)	1993-10-27	Fremgangsmaate for aa forhindre blokkering i katetere
IS3554A7 (is)	1990-08-24	Glýsín-afleiður og aðferð til framleiðslu þeirra

Legal Events

Date	Code	Title	Description
2004-08-31	FG	Patent granted	Owner name: DANA FARBER CANCER INSTITUTE