FI102181B1 - Process for obtaining ICAM-1 (intermolecular adhesion molecules) in substantially pure form - Google Patents

Process for obtaining ICAM-1 (intermolecular adhesion molecules) in substantially pure form

Info

Publication number: FI102181B1
Authority: FI; Finland
Prior art keywords: icam; obtaining; substantially pure; pure form; adhesion molecules
Prior art date: 1988-09-28

Application number

FI902490A

Other languages

Finnish (fi)

Swedish (sv)

Other versions

FI102181B (en

FI902490A0 (en

Inventor

Timothy A Springer

Robert Rothlein

Steven D Marlin

Michael L Dustin

Original Assignee

Dana Farber Cancer Inst Inc

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1988-09-28

Filing date

1990-05-21

Publication date

1998-10-30

1990-05-21 Application filed by Dana Farber Cancer Inst Inc filed Critical Dana Farber Cancer Inst Inc

1990-05-21 Publication of FI902490A0 publication Critical patent/FI902490A0/en

1998-10-30 Application granted granted Critical

1998-10-30 Publication of FI102181B publication Critical patent/FI102181B/en

1998-10-30 Publication of FI102181B1 publication Critical patent/FI102181B1/en

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/575—Hormones
- C07K14/655—Somatostatins
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
- C07K14/70503—Immunoglobulin superfamily
- C07K14/70525—ICAM molecules, e.g. CD50, CD54, CD102
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/04—Antineoplastic agents specific for metastasis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/2803—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily
- C07K16/2821—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily against ICAM molecules, e.g. CD50, CD54, CD102
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/2839—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the integrin superfamily
- C07K16/2845—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the integrin superfamily against integrin beta2-subunit-containing molecules, e.g. CD11, CD18
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
- C07K2317/34—Identification of a linear epitope shorter than 20 amino acid residues or of a conformational epitope defined by amino acid residues
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
- C07K2317/77—Internalization into the cell

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Life Sciences & Earth Sciences (AREA)
Immunology (AREA)
Medicinal Chemistry (AREA)
General Health & Medical Sciences (AREA)
General Chemical & Material Sciences (AREA)
Pharmacology & Pharmacy (AREA)
Animal Behavior & Ethology (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Chemical Kinetics & Catalysis (AREA)
Biochemistry (AREA)
Molecular Biology (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Biophysics (AREA)
Genetics & Genomics (AREA)
Bioinformatics & Cheminformatics (AREA)
Engineering & Computer Science (AREA)
Zoology (AREA)
Toxicology (AREA)
Pain & Pain Management (AREA)
Gastroenterology & Hepatology (AREA)
Transplantation (AREA)
Neurosurgery (AREA)
Rheumatology (AREA)
Cell Biology (AREA)
Neurology (AREA)
Oncology (AREA)
Biomedical Technology (AREA)
Endocrinology (AREA)
Peptides Or Proteins (AREA)
Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Preparation Of Compounds By Using Micro-Organisms (AREA)
Micro-Organisms Or Cultivation Processes Thereof (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

FI902490A 1988-09-28 1990-05-21 Process for obtaining ICAM-1 (intermolecular adhesion molecules) in substantially pure form FI102181B1 (en)

Applications Claiming Priority (6)

Application Number	Priority Date	Filing Date	Title
US25044688A	1988-09-28	1988-09-28
US25044688		1988-09-28
US37388289A	1989-06-30	1989-06-30
US37388289		1989-06-30
US8904242		1989-09-28
PCT/US1989/004242 WO1990003400A1 (en)	1988-09-28	1989-09-28	Intercellular adhesion molecules, and their binding ligands

Publications (3)

Publication Number	Publication Date
FI902490A0 FI902490A0 (en)	1990-05-21
FI102181B FI102181B (en)	1998-10-30
FI102181B1 true FI102181B1 (en)	1998-10-30

Family

ID=26940882

Family Applications (2)

Application Number	Title	Priority Date	Filing Date
FI902490A FI102181B1 (en)	1988-09-28	1990-05-21	Process for obtaining ICAM-1 (intermolecular adhesion molecules) in substantially pure form
FI981097A FI107451B (en)	1988-09-28	1998-05-18	A method for obtaining ICAM-1 (intercellular adhesion molecule) in substantially pure form

Family Applications After (1)

Application Number	Title	Priority Date	Filing Date
FI981097A FI107451B (en)	1988-09-28	1998-05-18	A method for obtaining ICAM-1 (intercellular adhesion molecule) in substantially pure form

Country Status (7)

Country	Link
JP (1)	JP2976381B2 (en)
KR (1)	KR900701846A (en)
AU (2)	AU4412889A (en)
DK (1)	DK175362B1 (en)
FI (2)	FI102181B1 (en)
HU (1)	HU218904B (en)
WO (1)	WO1990003400A1 (en)

Families Citing this family (27)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US6143298A (en) *	1988-09-01	2000-11-07	Bayer Corporation	Soluble truncated forms of ICAM-1
ZA896668B (en) *	1988-09-01	1990-06-27	Molecular Therapeutics Inc	A human rhinovirus receptor protein that inhibits virus infectivity
ATE219838T1 (en) *	1989-03-16	2002-07-15	Blood Res Center	USE OF FUNCTIONAL DERIVATIVES OF THE INTERCELLULAR ADHESION MOLECULE ICAM-1 IN AN ANTIVIRUS THERAPY
WO1991018010A1 (en) *	1990-05-15	1991-11-28	Swinburne Limited	Inhibition of viral infection using intercellular adhesion molecule-1-like peptides and/or analogues thereof
WO1991018011A1 (en) *	1990-05-15	1991-11-28	Swinburne Limited	Inhibition of cell adhesion using intercellular adhesion molecule-1-like peptides and/or analogues thereof
DK162890D0 (en) *	1990-07-06	1990-07-06	Novo Nordisk As	POLYPEPTIDE
US5686582A (en) *	1990-07-20	1997-11-11	Bayer Corporation	Multimeric forms of human rhinovirus receptor protein
US5686581A (en) *	1990-07-20	1997-11-11	Bayer Corporation	Multimeric form of human rhinovirus receptor protein
US6107461A (en) *	1990-07-20	2000-08-22	Bayer Corporation	Multimeric forms of human rhinovirus receptor and fragments thereof, and method of use
US5283058A (en)	1990-08-30	1994-02-01	The General Hospital Corporation	Methods for inhibiting rejection of transplanted tissue
CA2056143A1 (en) *	1990-11-28	1992-05-29	Michael S. Diamond	The mac-1 binding site of icam-1
US5932214A (en) *	1994-08-11	1999-08-03	Biogen, Inc.	Treatment for inflammatory bowel disease with VLA-4 blockers
US5599790A (en)	1992-06-11	1997-02-04	The Scripps Research Institute	Fibrinogen γ chain polypeptide and compositions thereof
EP0644768B1 (en) *	1992-06-11	2001-11-21	The Scripps Research Institute	Methods and compositions for inhibiting endothelial cell and fibrinogen mediated inflammation
EP0670734A4 (en) *	1992-10-09	1998-01-14	Blood Res Center	A subpopulation of mac-1 (cd11b/cd18) molecules which mediate neutrophil adhesion to icam-1 and fibrinogen.
DE4335273A1 (en) *	1993-10-15	1995-04-20	Univ Ludwigs Albert	Peptides for tumor therapy
AU698406B2 (en) *	1994-04-19	1998-10-29	University Of Kansas, The	ICAM-1/LFA-1 short-chain peptides and method of using same
AU6390696A (en) *	1995-06-20	1997-01-22	Trustees Of Boston University	Hypoxia-responsive adhesion molecules, specific antibodies, nd their uses
MXPA02002136A (en) *	1999-09-01	2002-09-18	Boehringer Ingelheim Pharma	Compositions for treating autoimmune disease containing a compounds which regulates icam lfa 1 interaction and a compounds which regulates cd40 cd40 ligand interaction.
US7314938B2 (en)	2003-11-05	2008-01-01	Sunesis Pharmaceuticals, Inc.	Modulators of cellular adhesion
AU2006247136C1 (en)	2005-05-17	2020-01-16	Bausch + Lomb Ireland Limited	Compositions and methods for treatment of eye disorders
JP5808037B2 (en)	2007-10-19	2015-11-10	サーコードバイオサイエンスインク．	Compositions and methods for the treatment of diabetic retinopathy
WO2009063965A1 (en) *	2007-11-15	2009-05-22	Chugai Seiyaku Kabushiki Kaisha	Monoclonal antibody capable of binding to anexelekto, and use thereof
US8080562B2 (en)	2008-04-15	2011-12-20	Sarcode Bioscience Inc.	Crystalline pharmaceutical and methods of preparation and use thereof
US8378105B2 (en)	2009-10-21	2013-02-19	Sarcode Bioscience Inc.	Crystalline pharmaceutical and methods of preparation and use thereof
MX2015001098A (en)	2012-07-25	2015-09-25	Sarcode Bioscience Inc	Lfa-1 inhibitor and polymorph thereof.
CN111417719B (en)	2017-11-30	2023-08-29	豪夫迈·罗氏有限公司	B cell culture method

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
DE3854536T2 (en) *	1987-05-04	1996-03-07	Dana Farber Cancer Inst Inc	Intercellular adhesion molecules and their binding ligands.
ATE114972T1 (en) *	1987-11-02	1994-12-15	Baylor College Medicine	USE OF ICAM-1 OR ITS FUNCTIONAL DERIVATIVES TO TREAT NON-SPECIFIC INFLAMMATION.

1989
- 1989-09-28 AU AU44128/89A patent/AU4412889A/en not_active Abandoned
- 1989-09-28 HU HU074/89A patent/HU218904B/en unknown
- 1989-09-28 WO PCT/US1989/004242 patent/WO1990003400A1/en active IP Right Grant
- 1989-09-28 JP JP1510885A patent/JP2976381B2/en not_active Expired - Lifetime
- 1989-09-28 KR KR1019900701105A patent/KR900701846A/en not_active IP Right Cessation
1990
- 1990-05-21 FI FI902490A patent/FI102181B1/en active IP Right Grant
- 1990-05-25 DK DK199001289A patent/DK175362B1/en not_active IP Right Cessation
1994
- 1994-05-19 AU AU63192/94A patent/AU679506B2/en not_active Expired
1998
- 1998-05-18 FI FI981097A patent/FI107451B/en active

Also Published As

Publication number	Publication date
FI102181B (en)	1998-10-30
KR900701846A (en)	1990-12-04
AU6319294A (en)	1994-08-25
DK128990D0 (en)	1990-05-25
FI981097A0 (en)	1989-09-28
JP2976381B2 (en)	1999-11-10
AU4412889A (en)	1990-04-18
FI107451B (en)	2001-08-15
HU896074D0 (en)	1990-11-28
HUT56120A (en)	1991-07-29
JPH03501861A (en)	1991-04-25
FI981097A (en)	1998-05-18
WO1990003400A1 (en)	1990-04-05
FI902490A0 (en)	1990-05-21
DK128990A (en)	1990-07-26
AU679506B2 (en)	1997-07-03
HU218904B (en)	2000-12-28
DK175362B1 (en)	2004-09-13

Publication	Publication Date	Title
FI102181B1 (en)	1998-10-30	Process for obtaining ICAM-1 (intermolecular adhesion molecules) in substantially pure form
GB8803574D0 (en)	1988-03-16	Improvements in/relating to stretch films
IT1201075B (en)	1989-01-27	METHOD AND APPARATUS FOR POSITIONING CLOTH ITEMS
ATA260986A (en)	1991-01-15	METHOD FOR PRODUCING CEFUROXIMAXETIL FILM TABLETS
AT383606B (en)	1987-07-27	METHOD FOR PRODUCING NEW TRANSPARENT COPOLYAMIDE MIXTURES THEREOF, AND THE USE THEREOF FOR PRODUCING MOLDED BODIES
NO180198C (en)	1997-03-05	Peptide synthesis method and solid support for use in the method
DE68917625D1 (en)	1994-09-29	Composite material and process for its manufacture.
AU586391B2 (en)	1989-07-06	Apparatus for gauge distribution in plastic tubing
NO902454D0 (en)	1990-06-01	MOUNTAIN CARD FOR FITTING IN THE REAR PLAN OF A SHORT FRAME
DK36289A (en)	1989-07-28	PROCEDURE AND APPARATUS FOR IMPLEMENTING WORKING OPERATIONS IN PUTS
FI895562A0 (en)	1989-11-22	Process for producing (S) -ethyl-2-oxo-1-pyrrolidine acetamide
FI894005A0 (en)	1989-08-25	Process for concentrating solutions
EP0338575A3 (en)	1990-05-23	Birefringent transparent film and process for producing the same
DE69005561D1 (en)	1994-02-10	Ceramic plate with inlaid ornament and process for its production.
IS3725A7 (en)	1991-12-29	Amino acid derivatives and process for their production
YU124289A (en)	1990-10-31	Process for obtaining alumoxane in waterless solution
ATE83466T1 (en)	1993-01-15	METHOD AND APPARATUS FOR MAKING PICTURE POSTCARDS.
GR900300096T1 (en)	1991-09-27	Adhesive for plastics, and process for using this adhesive
ATA265584A (en)	1988-07-15	METHOD AND DEVICE FOR THE PRODUCTION OF HEAT-SHRINKING TUBE FILMS ORIENTED IN TWO DIRECTIONS
DK110987A (en)	1987-09-11	PROCEDURE AND APPARATUS FOR EFFECTING THE BASIC PRODUCT BY FINDING IN WHEELS
GB2222994B (en)	1992-06-10	Improvements in or relating to conveying apparatus
DE68914263D1 (en)	1994-05-05	DEVICE FOR PRODUCING SCRATCHES IN TIRES.
DE3675631D1 (en)	1990-12-20	IN VITRO CULTURE PROCESS.
FR2633614B1 (en)	1991-06-07	PROCESS FOR MONOHALOGENATION IN (ALPHA) OF THE CARBONYL GROUPS OF THE KETONES
NO933877D0 (en)	1993-10-27	PROCEDURE FOR AA PREVENT BLOCK IN CATHETERS

Legal Events

Date	Code	Title	Description
2004-08-31	FG	Patent granted	Owner name: DANA FARBER CANCER INSTITUTE