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ES8802506A1 - Procedimiento para preparar derivados de fluoralcanos. - Google Patents

Procedimiento para preparar derivados de fluoralcanos.

Info

Publication number
ES8802506A1
ES8802506A1 ES554828A ES554828A ES8802506A1 ES 8802506 A1 ES8802506 A1 ES 8802506A1 ES 554828 A ES554828 A ES 554828A ES 554828 A ES554828 A ES 554828A ES 8802506 A1 ES8802506 A1 ES 8802506A1
Authority
ES
Spain
Prior art keywords
novel compound
fluoroalkane
derivatives
fluoroalkane derivatives
dioxan
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES554828A
Other languages
English (en)
Other versions
ES554828A0 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Imperial Chemical Industries Ltd
Original Assignee
Imperial Chemical Industries Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Imperial Chemical Industries Ltd filed Critical Imperial Chemical Industries Ltd
Publication of ES554828A0 publication Critical patent/ES554828A0/es
Publication of ES8802506A1 publication Critical patent/ES8802506A1/es
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D319/00—Heterocyclic compounds containing six-membered rings having two oxygen atoms as the only ring hetero atoms
    • C07D319/04—1,3-Dioxanes; Hydrogenated 1,3-dioxanes
    • C07D319/06—1,3-Dioxanes; Hydrogenated 1,3-dioxanes not condensed with other rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Hematology (AREA)
  • Pulmonology (AREA)
  • Diabetes (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Compounds That Contain Two Or More Ring Oxygen Atoms (AREA)
  • Magnetic Resonance Imaging Apparatus (AREA)

Abstract

EL FLUORANO ACIDO 4(Z)-6-[2,4,5-CIS]-4-O-HIDROXIFENIL-2-TRIFLUORMETIL-1,3-DIOXAN-5-IL)HEX ENOICO (I), SE OBTIENEN DESPROTEGIENDO UN DERIVADO FENOLICO (II), DONDE R ES UN PROTECTOR ADECUADO, COMO ALQUILO C1-16, ACILO Y ALILO, POR REACCION CON UN AGENTE DESPROTECTOR M.Z, DONDE M ES UN LITIO, SODIO O POTASIO Y Z TIOETOXIDO, HIDROXIDO Y DIFENILFOSFURO, EN UN DISOLVENTE COMO LA N,N-DIMETILFORMAMIDA O EL TETRAHIDROFURANO, ENTRE 30 Y 160GC. ANTAGONIZAN UNA O MAS DE LAS ACCIONES DEL TROMBOXANO A2 POR LO QUE SON APLICABLES AL TRATAMIENTO DE ENFERMEDADES EN LAS QUE ESTE ESTA IMPLICADO COMO INFARTO O ANGINA DE MIOCARDIO, ISQUEMIAS, ETC. *FORMULA*
ES554828A 1985-05-10 1986-05-09 Procedimiento para preparar derivados de fluoralcanos. Expired ES8802506A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB858511892A GB8511892D0 (en) 1985-05-10 1985-05-10 Fluoralkane derivatives

Publications (2)

Publication Number Publication Date
ES554828A0 ES554828A0 (es) 1988-07-16
ES8802506A1 true ES8802506A1 (es) 1988-07-16

Family

ID=10578946

Family Applications (1)

Application Number Title Priority Date Filing Date
ES554828A Expired ES8802506A1 (es) 1985-05-10 1986-05-09 Procedimiento para preparar derivados de fluoralcanos.

Country Status (14)

Country Link
US (1) US4902712A (es)
EP (1) EP0202084A3 (es)
JP (1) JPS61280487A (es)
AU (1) AU581080B2 (es)
DK (1) DK215786A (es)
ES (1) ES8802506A1 (es)
FI (1) FI861948A (es)
GB (1) GB8511892D0 (es)
GR (1) GR861204B (es)
HU (1) HU198468B (es)
NO (1) NO861866L (es)
NZ (1) NZ216111A (es)
PT (1) PT82548B (es)
ZA (1) ZA862993B (es)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5248780A (en) * 1988-02-16 1993-09-28 Imperial Chemical Industries, Plc Pyridyl substituted alkenoic acid derivatives
GB8901201D0 (en) * 1988-02-16 1989-03-15 Ici Plc Pyridine derivatives
GB9021571D0 (en) * 1990-10-04 1990-11-21 Ici Plc Heterocyclic acids
CA2676435C (en) * 2007-01-18 2015-03-24 Evolva Sa Substituted 1,3-dioxanes useful as ppar modulators

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8310407D0 (en) * 1982-05-12 1983-05-25 Ici Plc 1 3 - dioxan -5- ylalkenoic acids

Also Published As

Publication number Publication date
GB8511892D0 (en) 1985-06-19
HUT40795A (en) 1987-02-27
EP0202084A3 (en) 1987-04-01
HU198468B (en) 1989-10-30
JPS61280487A (ja) 1986-12-11
ES554828A0 (es) 1988-07-16
US4902712A (en) 1990-02-20
GR861204B (en) 1986-08-29
PT82548A (en) 1986-06-01
NO861866L (no) 1986-11-11
PT82548B (pt) 1988-08-17
DK215786D0 (da) 1986-05-09
ZA862993B (en) 1986-12-30
AU581080B2 (en) 1989-02-09
NZ216111A (en) 1989-08-29
EP0202084A2 (en) 1986-11-20
FI861948A (fi) 1986-11-11
FI861948A0 (fi) 1986-05-09
AU5706786A (en) 1986-11-13
DK215786A (da) 1986-11-11

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