[go: up one dir, main page]
More Web Proxy on the site http://driver.im/

ES8307222A1 - A novel enantioselective synthesis of N-substituted proline derivatives - Google Patents

A novel enantioselective synthesis of N-substituted proline derivatives

Info

Publication number
ES8307222A1
ES8307222A1 ES512564A ES512564A ES8307222A1 ES 8307222 A1 ES8307222 A1 ES 8307222A1 ES 512564 A ES512564 A ES 512564A ES 512564 A ES512564 A ES 512564A ES 8307222 A1 ES8307222 A1 ES 8307222A1
Authority
ES
Spain
Prior art keywords
enantioselective synthesis
proline derivatives
substituted proline
novel enantioselective
novel
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES512564A
Other languages
Spanish (es)
Other versions
ES512564A0 (en
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
CRC Compagnie di Ricerca Chimica SpA
Original Assignee
CRC Compagnie di Ricerca Chimica SpA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from IT21984/81A external-priority patent/IT1194797B/en
Priority claimed from IT21201/82A external-priority patent/IT1151754B/en
Application filed by CRC Compagnie di Ricerca Chimica SpA filed Critical CRC Compagnie di Ricerca Chimica SpA
Publication of ES8307222A1 publication Critical patent/ES8307222A1/en
Publication of ES512564A0 publication Critical patent/ES512564A0/en
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D513/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
    • C07D513/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains two hetero rings
    • C07D513/04—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/04—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D207/10—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D207/16—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pyrrole Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Peptides Or Proteins (AREA)

Abstract

The invention relates to a novel enantioselective synthesis of the compound N-[(2S)-3-mercapto-2-methylpropionyl]-S-proline of the formula I: < IMAGE > in which X denotes an SH group, using cyclic compounds of the formula II: < IMAGE > in which Y denotes sulphur or oxygen, as starting material.
ES512564A 1981-05-27 1982-05-26 "A PROCEDURE FOR THE ENANTIOSELECTIVE PREPARATION OF N-SUBSTITUTED PROLINE DERIVATIVES". Granted ES512564A0 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IT21984/81A IT1194797B (en) 1981-05-27 1981-05-27 PROCEDURE FOR ENANTIOSELECTIVE PREPARATION OF N-SUBSTITUTED DERIVATIVES OF PROLINA
IT21201/82A IT1151754B (en) 1982-05-11 1982-05-11 Prepn. of 3-mercapto-2-methyl propionyl-proline and precursors

Publications (2)

Publication Number Publication Date
ES8307222A1 true ES8307222A1 (en) 1983-07-01
ES512564A0 ES512564A0 (en) 1983-07-01

Family

ID=26327821

Family Applications (1)

Application Number Title Priority Date Filing Date
ES512564A Granted ES512564A0 (en) 1981-05-27 1982-05-26 "A PROCEDURE FOR THE ENANTIOSELECTIVE PREPARATION OF N-SUBSTITUTED PROLINE DERIVATIVES".

Country Status (6)

Country Link
DE (1) DE3219985A1 (en)
ES (1) ES512564A0 (en)
FI (1) FI77037C (en)
GR (1) GR76449B (en)
NL (1) NL8202153A (en)
SE (1) SE8203245L (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2035798A1 (en) * 1990-09-21 1993-04-16 Egyt Gyogyszervegyeszeti Gyar Process for preparing 1-(2s)-3-mercapto-methyl-1-oxopropyl)-l-proline

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL180746C (en) * 1983-11-18 1987-04-16 Matthijs Cornelis Evers PROCESS FOR PREPARING CAPTOPRIL.

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU509899B2 (en) * 1976-02-13 1980-05-29 E.R. Squibb & Sons, Inc. Proline derivatives and related compounds

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2035798A1 (en) * 1990-09-21 1993-04-16 Egyt Gyogyszervegyeszeti Gyar Process for preparing 1-(2s)-3-mercapto-methyl-1-oxopropyl)-l-proline

Also Published As

Publication number Publication date
FI821859A0 (en) 1982-05-26
ES512564A0 (en) 1983-07-01
GR76449B (en) 1984-08-10
SE8203245L (en) 1982-11-28
FI77037C (en) 1989-01-10
FI77037B (en) 1988-09-30
NL8202153A (en) 1982-12-16
DE3219985A1 (en) 1982-12-16

Similar Documents

Publication Publication Date Title
DE3069408D1 (en) 5-oxo- and 5-thioxoproline derivatives, process for their production and pharmaceutical compositions containing them
ES8400737A1 (en) New herbicidal nicotinamide derivatives.
ES469567A1 (en) Organic compounds
ES2005745A6 (en) Process for the preparation of aryl-piperidine carbinols.
ES2054826T3 (en) PEPTIDES WITH COLAGENASA INHIBITING ACTIVITY.
ES8402268A1 (en) Indole-5-acetamides for treatment of migraine
ES8407471A1 (en) Disubstituted proline derivatives, process for their preparation and their use.
ES8405757A1 (en) Amine derivatives, processes for their production and pharmaceutical compositions containing them.
JPS5665869A (en) Novel 22hydroxyalkyll3*4*55trihydroxyypiperidine compound* its manufacture and drug
MY105538A (en) Derivatives of thieno-triazolo-diazepine, a preparation process of the same and therapeutic compositions containing them.
AU4611589A (en) Enzyme-inhibiting amino acid derivatives, a process for the preparation thereof, agents containing these, and the use thereof.
ZA912618B (en) 3-aminochroman derivatives,process for preparing these and pharmaceutical compositions containing them
JPS6416791A (en) Guanidine related compound containing substituted tetraphenylborate ion and its production
ES8307222A1 (en) A novel enantioselective synthesis of N-substituted proline derivatives
ES8609319A1 (en) Phenylnaphthyridines, process for their preparation, medicaments containing them, particularly as anti-ulcer agents.
ES2001953A6 (en) Synthesis of beta-lactam compounds.
IE822391L (en) 4-acylamino-1-azaadamantanes
DE69416003D1 (en) Kristalline, polymorphische form von (s,s,s)-n-(1-[2-carboxy-3-(n2-mesyllysylamino)propyl]-1-cyclopentylcarbonyl)tyrosin
ES480969A1 (en) Cationic fluorescent whitening agents
ES8302093A1 (en) Novel beta-lactam compounds, process for production thereof, and medicines containing them.
JPS6416792A (en) Guanidine related compound containing tetraphenylborate ion, its production and use thereof in peptide synthesis
ES8600759A1 (en) +/- 2-(Phenethyl)-5-((3,4-methylenedioxy)-alpha-hydroxybenzyl)-pyrrolidines, pharmaceutical compositions containing them, processes for their production and intermediates therefor.
ES481741A1 (en) Synthetic intermediates for the preparation of diaromatic O-(amino-alkyl)oximes
ES8506702A1 (en) Furyloxazolylacetic acid derivative, processes for preparing same and pharmaceutical composition.
ES8600760A1 (en) +/- 2-((3,4-Methylenedioxy)phenethyl)-5-((3-carboxamido-4-hydroxy)-alpha-hydroxybenzyl)pyrrolidines, pharmaceutical compositions containing them, process for their production and intermediates therefor.

Legal Events

Date Code Title Description
MM4A Patent lapsed

Effective date: 19960506