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ES8106542A1 - Un procedimiento para la preparacion de un copolimero. - Google Patents

Un procedimiento para la preparacion de un copolimero.

Info

Publication number
ES8106542A1
ES8106542A1 ES494974A ES494974A ES8106542A1 ES 8106542 A1 ES8106542 A1 ES 8106542A1 ES 494974 A ES494974 A ES 494974A ES 494974 A ES494974 A ES 494974A ES 8106542 A1 ES8106542 A1 ES 8106542A1
Authority
ES
Spain
Prior art keywords
acid
copolymer
making same
lactic acid
glycolic
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES494974A
Other languages
English (en)
Other versions
ES494974A0 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Eli Lilly and Co
Original Assignee
Eli Lilly and Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Eli Lilly and Co filed Critical Eli Lilly and Co
Publication of ES8106542A1 publication Critical patent/ES8106542A1/es
Publication of ES494974A0 publication Critical patent/ES494974A0/es
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
    • C08G63/00—Macromolecular compounds obtained by reactions forming a carboxylic ester link in the main chain of the macromolecule
    • C08G63/78—Preparation processes
    • C08G63/82—Preparation processes characterised by the catalyst used
    • C08G63/823—Preparation processes characterised by the catalyst used for the preparation of polylactones or polylactides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/34—Macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyesters, polyamino acids, polysiloxanes, polyphosphazines, copolymers of polyalkylene glycol or poloxamers
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
    • C08G63/00—Macromolecular compounds obtained by reactions forming a carboxylic ester link in the main chain of the macromolecule
    • C08G63/02—Polyesters derived from hydroxycarboxylic acids or from polycarboxylic acids and polyhydroxy compounds
    • C08G63/06—Polyesters derived from hydroxycarboxylic acids or from polycarboxylic acids and polyhydroxy compounds derived from hydroxycarboxylic acids

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Polymers & Plastics (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Inorganic Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Polyesters Or Polycarbonates (AREA)
  • Medicinal Preparation (AREA)
  • Biological Depolymerization Polymers (AREA)

Abstract

PROCEDIMIENTO DE OBTENCION DE COPOLIMEROS. CONSISTE EN SOMETER A POLIMERIZACION ACIDO LACTICO Y ACIDO GLICOLICO EN PRESENCIA DE UNA RESINA DE INTERCAMBIO IONICO FUERTEMENTE ACIDO Y FACILMENTE SEPARABLE. LA POLIMERIZACION SE EFECTUA A UNA TEMPERATURA DE 100 A 250 GC DURANTE UN TIEMPO DE TRES A 172 HORAS. EN LA RELACION INTERVIENE UN 70 POR 100 EN PESO DE ACIDO LACTICO Y UN 30 POR 100 DE ACIDO GLICOLICO. LA RESINA DE INTERCAMBIO IONICO ES DOWEX HCR-W2-H O DE AMBERLYSTELS. EL COPOLIMERO OBTENIDO TIENE UNA VISCOSIDAD INHERENTE AL CLOROFORMO DE 0,08 A 0,30, CON UN PESO MOLECULAR PROMEDIO DE 6.000 A 35.000, ESTANDO EXENTO DE UN CATALIZADOR DE POLIMERIZACION.
ES494974A 1979-09-12 1980-09-11 Un procedimiento para la preparacion de un copolimero. Granted ES494974A0 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US06/075,296 US4273920A (en) 1979-09-12 1979-09-12 Polymerization process and product

Publications (2)

Publication Number Publication Date
ES8106542A1 true ES8106542A1 (es) 1981-08-16
ES494974A0 ES494974A0 (es) 1981-08-16

Family

ID=22124778

Family Applications (1)

Application Number Title Priority Date Filing Date
ES494974A Granted ES494974A0 (es) 1979-09-12 1980-09-11 Un procedimiento para la preparacion de un copolimero.

Country Status (31)

Country Link
US (1) US4273920A (es)
EP (1) EP0026599B1 (es)
JP (2) JPS5645920A (es)
AR (1) AR221173A1 (es)
AT (1) AT380689B (es)
AU (1) AU539130B2 (es)
BE (1) BE885182A (es)
BG (1) BG41132A3 (es)
CA (1) CA1185048A (es)
CH (1) CH648048A5 (es)
CS (1) CS221979B2 (es)
DD (1) DD153125A5 (es)
DE (1) DE3068116D1 (es)
DK (1) DK155093C (es)
EG (1) EG14381A (es)
ES (1) ES494974A0 (es)
FI (1) FI66412C (es)
FR (1) FR2464973A1 (es)
GB (1) GB2058808B (es)
GR (1) GR69961B (es)
GT (1) GT198065361A (es)
HU (1) HU191807B (es)
IE (1) IE50236B1 (es)
IL (1) IL61024A (es)
IT (1) IT1141040B (es)
NZ (1) NZ194902A (es)
PH (1) PH15272A (es)
PL (1) PL129779B1 (es)
PT (1) PT71794B (es)
RO (1) RO80864A (es)
ZA (1) ZA805629B (es)

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Also Published As

Publication number Publication date
BE885182A (fr) 1981-03-11
ATA455380A (de) 1985-11-15
EG14381A (en) 1983-12-31
EP0026599B1 (en) 1984-06-06
PH15272A (en) 1982-11-02
ZA805629B (en) 1982-04-28
FR2464973B1 (es) 1983-06-10
JPS5645920A (en) 1981-04-25
JPH0198617A (ja) 1989-04-17
DE3068116D1 (en) 1984-07-12
FI66412C (fi) 1984-10-10
IE50236B1 (en) 1986-03-05
DD153125A5 (de) 1981-12-23
HU191807B (en) 1987-04-28
IE801902L (en) 1981-03-12
CS221979B2 (en) 1983-04-29
FI802840A (fi) 1981-03-13
CH648048A5 (fr) 1985-02-28
GB2058808B (en) 1983-11-16
NZ194902A (en) 1983-05-31
PL226653A1 (es) 1981-10-16
PT71794A (en) 1980-10-01
ES494974A0 (es) 1981-08-16
JPH0445525B2 (es) 1992-07-27
IT1141040B (it) 1986-10-01
GT198065361A (es) 1982-03-04
EP0026599A1 (en) 1981-04-08
JPH0121166B2 (es) 1989-04-20
AU539130B2 (en) 1984-09-13
AU6216680A (en) 1981-03-19
US4273920A (en) 1981-06-16
CA1185048A (en) 1985-04-02
FR2464973A1 (fr) 1981-03-20
IL61024A (en) 1983-02-23
GB2058808A (en) 1981-04-15
IL61024A0 (en) 1980-11-30
AT380689B (de) 1986-06-25
DK155093C (da) 1989-06-19
PT71794B (en) 1981-07-07
IT8024607A0 (it) 1980-09-11
DK155093B (da) 1989-02-06
DK387380A (da) 1981-03-13
RO80864A (ro) 1983-02-01
FI66412B (fi) 1984-06-29
PL129779B1 (en) 1984-06-30
AR221173A1 (es) 1980-12-30
BG41132A3 (en) 1987-04-15
GR69961B (es) 1982-07-22

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