ES520784A0 - Un procedimiento para la preparacion de un derivado del indol. - Google Patents

Un procedimiento para la preparacion de un derivado del indol.

Info

Publication number: ES520784A0
Authority: ES; Spain
Prior art keywords: indol; derivative; procedure; preparation
Prior art date: 1980-08-12
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.): Granted

Application number

ES520784A

Other languages

English (en)

Other versions

ES8500902A1 (es

Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)

Glaxo Group Ltd

Original Assignee

Glaxo Group Ltd

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1980-08-12

Filing date

1983-03-18

Publication date

1984-11-01

1983-03-18 Application filed by Glaxo Group Ltd filed Critical Glaxo Group Ltd

1984-11-01 Publication of ES520784A0 publication Critical patent/ES520784A0/es

1984-11-01 Publication of ES8500902A1 publication Critical patent/ES8500902A1/es

Status Expired legal-status Critical Current

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/44—Iso-indoles; Hydrogenated iso-indoles
- C07D209/48—Iso-indoles; Hydrogenated iso-indoles with oxygen atoms in positions 1 and 3, e.g. phthalimide
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C243/00—Compounds containing chains of nitrogen atoms singly-bound to each other, e.g. hydrazines, triazanes
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C251/00—Compounds containing nitrogen atoms doubly-bound to a carbon skeleton
- C07C251/72—Hydrazones
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C255/00—Carboxylic acid nitriles
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/04—Indoles; Hydrogenated indoles
- C07D209/10—Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
- C07D209/14—Radicals substituted by nitrogen atoms, not forming part of a nitro radical
- C07D209/16—Tryptamines
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/04—Indoles; Hydrogenated indoles
- C07D209/10—Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
- C07D209/18—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Public Health (AREA)
Life Sciences & Earth Sciences (AREA)
Veterinary Medicine (AREA)
Engineering & Computer Science (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Pharmacology & Pharmacy (AREA)
Bioinformatics & Cheminformatics (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Heart & Thoracic Surgery (AREA)
Cardiology (AREA)
Pain & Pain Management (AREA)
Biomedical Technology (AREA)
Neurology (AREA)
Neurosurgery (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Indole Compounds (AREA)

ES520784A 1980-08-12 1983-03-18 Un procedimiento para la preparacion de un derivado del indol. Expired ES8500902A1 (es)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
GB8026286		1980-08-12

Publications (2)

Publication Number	Publication Date
ES520784A0 true ES520784A0 (es)	1984-11-01
ES8500902A1 ES8500902A1 (es)	1984-11-01

Family

ID=10515410

Family Applications (5)

Application Number	Title	Priority Date	Filing Date
ES504693A Expired ES8301210A1 (es)	1980-08-12	1981-08-11	Un procedimiento para la preparacion de un derivado del indol.
ES513933A Granted ES513933A0 (es)	1980-08-12	1982-07-13	Un procedimiento para la preparacion de un derivado del indol.
ES520785A Expired ES8500903A1 (es)	1980-08-12	1983-03-18	Un procedimiento para la preparacion de un derivado del indol.
ES520784A Expired ES8500902A1 (es)	1980-08-12	1983-03-18	Un procedimiento para la preparacion de un derivado del indol.
ES520783A Expired ES8504706A1 (es)	1980-08-12	1983-03-18	Un procedimiento para la preparacion de un derivado del indol.

Family Applications Before (3)

Application Number	Title	Priority Date	Filing Date
ES504693A Expired ES8301210A1 (es)	1980-08-12	1981-08-11	Un procedimiento para la preparacion de un derivado del indol.
ES513933A Granted ES513933A0 (es)	1980-08-12	1982-07-13	Un procedimiento para la preparacion de un derivado del indol.
ES520785A Expired ES8500903A1 (es)	1980-08-12	1983-03-18	Un procedimiento para la preparacion de un derivado del indol.

Family Applications After (1)

Application Number	Title	Priority Date	Filing Date
ES520783A Expired ES8504706A1 (es)	1980-08-12	1983-03-18	Un procedimiento para la preparacion de un derivado del indol.

Country Status (16)

Country	Link
US (1)	US4650810A (es)
JP (1)	JPS5764669A (es)
AU (1)	AU548467B2 (es)
BE (1)	BE889929A (es)
CA (1)	CA1169428A (es)
CH (1)	CH651551A5 (es)
DE (1)	DE3131728A1 (es)
DK (1)	DK157920C (es)
ES (5)	ES8301210A1 (es)
FR (1)	FR2488607A1 (es)
IE (1)	IE51491B1 (es)
IT (1)	IT1171449B (es)
NL (1)	NL8103769A (es)
NZ (1)	NZ197996A (es)
SE (1)	SE454880B (es)
ZA (1)	ZA815540B (es)

Families Citing this family (25)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
IT1170387B (it) *	1982-06-07	1987-06-03	Glaxo Group Ltd	Composti eterociclici, procedimento per prepararli e composizioni farmaceutiche che li contengono
GB8332435D0 (en) *	1983-12-06	1984-01-11	Glaxo Group Ltd	Chemical compounds
GB8419575D0 (en) *	1984-08-01	1984-09-05	Glaxo Group Ltd	Chemical compounds
EP0225726B1 (en) *	1985-11-08	1991-04-17	Glaxo Group Limited	Indole derivatives
GB8530507D0 (en) *	1985-12-11	1986-01-22	Glaxo Group Plc	Chemical compounds
US5270333A (en) *	1986-01-28	1993-12-14	Glaxo Group Limited	Indole derivatives
GB8607824D0 (en) *	1986-03-27	1986-04-30	Glaxo Group Ltd	Chemical compounds
NZ238424A (en) *	1990-06-07	1993-12-23	Wellcome Found	3,5-substituted indole derivatives; medicaments and preparatory processes.
SK278998B6 (sk) *	1991-02-01	1998-05-06	Merck Sharp & Dohme Limited	Deriváty imidazolu, triazolu a tetrazolu, spôsob i
US5254383A (en) *	1992-09-14	1993-10-19	Allied-Signal Inc.	Composites having improved penetration resistance and articles fabricated from same
FR2701026B1 (fr) *	1993-02-02	1995-03-31	Adir	Nouveaux dérivés de l'indole, de l'indazole et du benzisoxazole, leur procédé de préparation et les compositions pharmaceutiques qui les contiennent.
US5468768A (en) *	1994-01-06	1995-11-21	Bristol-Myers Squibb Company	Antimigraine derivatives of indolylcycloalkanylamines
ES2084560B1 (es) *	1994-03-09	1997-01-16	Almirall Lab	Procedimiento de preparacion de derivados el indol.
US5891885A (en) *	1996-10-09	1999-04-06	Algos Pharmaceutical Corporation	Method for treating migraine
US20030096379A1 (en) *	2001-03-28	2003-05-22	Kilgore James L.	Method for producing tryptamine derivatives
US6685951B2 (en)	2001-07-05	2004-02-03	R. T. Alamo Ventures I, Inc.	Administration of dihydroergotamine as a sublingual spray or aerosol for the treatment of migraine
US20030017175A1 (en) *	2001-07-05	2003-01-23	R.T. Alamo Ventures I, Inc.	Sublingual administration of dihydroergotamine for the treatment of migraine
US20030198669A1 (en) *	2001-07-05	2003-10-23	R.T. Alamo Ventures I, Llc	Compositions and methods for rapid dissolving formulations of dihydroergotamine and caffeine for the treatment of migraine
CA2508290C (en) *	2002-12-20	2017-02-28	Ciba Specialty Chemicals Holding Inc.	Synthesis of amines and intermediates for the synthesis thereof
ES2538082T3 (es) *	2007-02-11	2015-06-17	Map Pharmaceuticals Inc	Método de administración terapéutica de DHE para permitir el rápido alivio de migraña mientras que se minimiza el perfil de efectos secundarios
CL2008000838A1 (es) *	2007-03-23	2008-10-10	Neuraxon Inc	Compuestos derivados de quinolina y tetrahidroquinolina, con actividad inhibidora nos; composicion farmaceutica que comprende a dichos compuestos; y su uso para tratar un dolor de cabeza tal como migrana, dolor cronico, desordenes del sistema nervios
KR20090125799A (ko)	2007-03-29	2009-12-07	아스비오파마 가부시키가이샤	Ｃｐｌａ2 저해 활성을 가지는 인돌 유도체 및 그 용도 및 제조 방법
US20110171141A1 (en) *	2009-06-26	2011-07-14	Kellerman Donald J	Administration of dihydroergotamine mesylate particles using a metered dose inhaler
WO2013016223A2 (en)	2011-07-22	2013-01-31	The University Of Chicago	Treatments for migraine and related disorders
EP2935280A4 (en)	2012-12-21	2016-05-25	Map Pharmaceuticals Inc	8'-HYDROXY-DIHYDROERGOTAMINE COMPOUNDS AND COMPOSITIONS

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US3182071A (en) *	1961-06-27	1965-05-04	Warner Lambert Pharmaceutical	Acylated indole derivatives
US3472870A (en) *	1966-08-29	1969-10-14	Mead Johnson & Co	Sulfonamidotryptamines
ZA795239B (en) *	1978-10-12	1980-11-26	Glaxo Group Ltd	Heterocyclic compounds

1981
- 1981-08-11 AU AU73994/81A patent/AU548467B2/en not_active Ceased
- 1981-08-11 DE DE19813131728 patent/DE3131728A1/de active Granted
- 1981-08-11 IT IT49084/81A patent/IT1171449B/it active
- 1981-08-11 ES ES504693A patent/ES8301210A1/es not_active Expired
- 1981-08-11 SE SE8104781A patent/SE454880B/sv not_active IP Right Cessation
- 1981-08-11 DK DK357081A patent/DK157920C/da not_active IP Right Cessation
- 1981-08-11 NL NL8103769A patent/NL8103769A/nl not_active Application Discontinuation
- 1981-08-11 BE BE0/205642A patent/BE889929A/fr not_active IP Right Cessation
- 1981-08-11 NZ NZ197996A patent/NZ197996A/en unknown
- 1981-08-11 ZA ZA815540A patent/ZA815540B/xx unknown
- 1981-08-11 FR FR8115513A patent/FR2488607A1/fr active Granted
- 1981-08-11 CH CH5159/81A patent/CH651551A5/fr not_active IP Right Cessation
- 1981-08-11 IE IE1830/81A patent/IE51491B1/en unknown
- 1981-08-12 CA CA000383670A patent/CA1169428A/en not_active Expired
- 1981-08-12 JP JP56125411A patent/JPS5764669A/ja active Granted
1982
- 1982-07-13 ES ES513933A patent/ES513933A0/es active Granted
1983
- 1983-01-26 US US06/461,233 patent/US4650810A/en not_active Expired - Fee Related
- 1983-03-18 ES ES520785A patent/ES8500903A1/es not_active Expired
- 1983-03-18 ES ES520784A patent/ES8500902A1/es not_active Expired
- 1983-03-18 ES ES520783A patent/ES8504706A1/es not_active Expired

Also Published As

Publication number	Publication date
ES520783A0 (es)	1985-05-01
FR2488607B1 (es)	1984-11-16
CH651551A5 (fr)	1985-09-30
ES520785A0 (es)	1984-11-01
FR2488607A1 (fr)	1982-02-19
DE3131728C2 (es)	1992-04-30
AU7399481A (en)	1982-02-18
ES504693A0 (es)	1982-12-01
IE51491B1 (en)	1987-01-07
NZ197996A (en)	1985-08-16
DK157920B (da)	1990-03-05
ES8402268A1 (es)	1984-01-16
DK357081A (da)	1982-02-13
IT8149084A0 (it)	1981-08-11
DK157920C (da)	1990-08-06
US4650810A (en)	1987-03-17
AU548467B2 (en)	1985-12-12
DE3131728A1 (de)	1982-03-11
SE454880B (sv)	1988-06-06
ES8301210A1 (es)	1982-12-01
ES8504706A1 (es)	1985-05-01
CA1169428A (en)	1984-06-19
ES8500903A1 (es)	1984-11-01
NL8103769A (nl)	1982-03-01
ZA815540B (en)	1983-03-30
ES513933A0 (es)	1984-01-16
ES8500902A1 (es)	1984-11-01
JPS5764669A (en)	1982-04-19
SE8104781L (sv)	1982-02-13
JPH0247462B2 (es)	1990-10-19
IT1171449B (it)	1987-06-10
BE889929A (fr)	1982-02-11
IE811830L (en)	1982-02-12

Publication	Publication Date	Title
ES504695A0 (es)	1982-11-01	Un procedimiento para la preparacion de un derivado del indol.
ES520783A0 (es)	1985-05-01	Un procedimiento para la preparacion de un derivado del indol.
ES501766A0 (es)	1983-02-01	Un procedimiento para la preparacion de derivados del 1,2,5-tiadiazol.
ES544281A0 (es)	1986-07-16	Un procedimiento para la preparacion de derivados del indol
ES508286A0 (es)	1983-02-16	Un procedimiento para la preparacion de derivados de imidazolil-propanol.
ES507298A0 (es)	1983-02-16	Un procedimiento para la preparacion de derivados de 2-feniletanolamina.
ES503790A0 (es)	1982-11-01	Un procedimiento para la preparacion de una composicion de derivados del imidazor.
ES513934A0 (es)	1984-06-01	Un procedimiento para la preparacion de derivados del indol.
ES507960A0 (es)	1983-10-01	Un procedimiento para la mejoracion de 3-(pirid-3-0,4-ilalquil)indoles
ES519057A0 (es)	1984-03-16	Un procedimiento para la preparacion de derivados de caprolactama.
ES505922A0 (es)	1983-01-01	Un procedimiento para la preparacion de nuevos derivados de cefalospirina.
ES513765A0 (es)	1983-04-01	Un procedimiento para la preparacion de derivados del indol.
ES514039A0 (es)	1983-12-01	Un procedimiento para la preparacion de indol sulfonilureas.
ES507755A0 (es)	1983-02-01	Un procedimiento para la preparacion de un derivado de 2-piridincarboxamida.
ES501339A0 (es)	1983-01-16	Un procedimiento para la preparacion de derivados de 9-carbamoil-9-aminoalquilfluoreno.
ES504790A0 (es)	1982-12-01	Un procedimiento para la preparacion de derivados de enantolactama.
ES504793A0 (es)	1982-12-16	Un procedimiento para la preparacion de nuevos derivados de caprilolactama.
ES513130A0 (es)	1983-04-01	Un procedimiento para la preparacion de nuevos derivados del indeno.
ES507015A0 (es)	1982-08-16	Procedimiento para la preparacion de nuevas indolinonas.
ES507034A0 (es)	1983-07-01	Un procedimiento para la preparacion de derivados tetrasubs-tituidos del benceno.
ES504577A0 (es)	1982-12-16	Un procedimiento para la preparacion de derivados de piridazinona.
ES503338A0 (es)	1982-11-01	Un procedimiento para la preparacion de derivados de bis-hidroxibencilo.
ES505920A0 (es)	1983-01-01	Un procedimiento para la preparacion de derivados de isonicotinanilida.
ES507918A0 (es)	1983-04-01	Un procedimiento para la preparacion de benzamitas sustituidas.
ES507482A0 (es)	1983-02-16	Un procedimiento para la preparacion de nuevos derivados de acilaminoquimazolina.