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ES454085A1 - Procedimiento para la preparacion de n-(r-tetrahidrofurfu- ril)-noroximorfona y n-(s-tetrahidrofurfuril)-noroximorfona nuevas. - Google Patents

Procedimiento para la preparacion de n-(r-tetrahidrofurfu- ril)-noroximorfona y n-(s-tetrahidrofurfuril)-noroximorfona nuevas.

Info

Publication number
ES454085A1
ES454085A1 ES454085A ES454085A ES454085A1 ES 454085 A1 ES454085 A1 ES 454085A1 ES 454085 A ES454085 A ES 454085A ES 454085 A ES454085 A ES 454085A ES 454085 A1 ES454085 A1 ES 454085A1
Authority
ES
Spain
Prior art keywords
tetrahydrofurfuril
noroximorphone
translation
preparation
machine
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES454085A
Other languages
English (en)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
CH Boehringer Sohn AG and Co KG
Original Assignee
CH Boehringer Sohn AG and Co KG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by CH Boehringer Sohn AG and Co KG filed Critical CH Boehringer Sohn AG and Co KG
Publication of ES454085A1 publication Critical patent/ES454085A1/es
Expired legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D489/00Heterocyclic compounds containing 4aH-8, 9 c- Iminoethano-phenanthro [4, 5-b, c, d] furan ring systems, e.g. derivatives of [4, 5-epoxy]-morphinan of the formula:
    • C07D489/06Heterocyclic compounds containing 4aH-8, 9 c- Iminoethano-phenanthro [4, 5-b, c, d] furan ring systems, e.g. derivatives of [4, 5-epoxy]-morphinan of the formula: with a hetero atom directly attached in position 14
    • C07D489/08Oxygen atom
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/04Centrally acting analgesics, e.g. opioids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/30Drugs for disorders of the nervous system for treating abuse or dependence

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Addiction (AREA)
  • Psychiatry (AREA)
  • Pain & Pain Management (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Saccharide Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
ES454085A 1975-08-27 1976-12-09 Procedimiento para la preparacion de n-(r-tetrahidrofurfu- ril)-noroximorfona y n-(s-tetrahidrofurfuril)-noroximorfona nuevas. Expired ES454085A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19752538075 DE2538075A1 (de) 1975-08-27 1975-08-27 N-tetrahydrofurfuryl-noroxymorphone, deren saeureadditionssalze, diese enthaltende arzneimittel sowie verfahren zu ihrer herstellung

Publications (1)

Publication Number Publication Date
ES454085A1 true ES454085A1 (es) 1977-11-16

Family

ID=5954931

Family Applications (5)

Application Number Title Priority Date Filing Date
ES450897A Expired ES450897A1 (es) 1975-08-27 1976-08-21 Procedimiento para la preparacion de n-(r-tetrahidrofurfu- ril)-noroximorfona y n-(s-tetrahidrofurfuril)-noroximorfona.
ES454084A Expired ES454084A1 (es) 1975-08-27 1976-12-09 Procedimiento para la preparmacion de n-(r-tetrahidrofurfu- ril)-noroximorfona y n-(s-tetrahidrofurfuril)-noroximorfona nuevas.
ES454087A Expired ES454087A2 (es) 1975-08-27 1976-12-09 Procedimiento para la preparacion de n-(r-tetrahidrofurfu- ril)-noroximorfona y n-(s-tetrahidrofurfuril)-noroximorfona nuevas.
ES454085A Expired ES454085A1 (es) 1975-08-27 1976-12-09 Procedimiento para la preparacion de n-(r-tetrahidrofurfu- ril)-noroximorfona y n-(s-tetrahidrofurfuril)-noroximorfona nuevas.
ES454086A Expired ES454086A1 (es) 1975-08-27 1976-12-09 Procedimiento para la preparacion de n-(r-tetrahidrofurfu- ril)-noroximorfona y n-(s-tetrahidrofurfuril)-norosimorfona nuevas.

Family Applications Before (3)

Application Number Title Priority Date Filing Date
ES450897A Expired ES450897A1 (es) 1975-08-27 1976-08-21 Procedimiento para la preparacion de n-(r-tetrahidrofurfu- ril)-noroximorfona y n-(s-tetrahidrofurfuril)-noroximorfona.
ES454084A Expired ES454084A1 (es) 1975-08-27 1976-12-09 Procedimiento para la preparmacion de n-(r-tetrahidrofurfu- ril)-noroximorfona y n-(s-tetrahidrofurfuril)-noroximorfona nuevas.
ES454087A Expired ES454087A2 (es) 1975-08-27 1976-12-09 Procedimiento para la preparacion de n-(r-tetrahidrofurfu- ril)-noroximorfona y n-(s-tetrahidrofurfuril)-noroximorfona nuevas.

Family Applications After (1)

Application Number Title Priority Date Filing Date
ES454086A Expired ES454086A1 (es) 1975-08-27 1976-12-09 Procedimiento para la preparacion de n-(r-tetrahidrofurfu- ril)-noroximorfona y n-(s-tetrahidrofurfuril)-norosimorfona nuevas.

Country Status (33)

Country Link
US (1) US4100288A (es)
JP (1) JPS5231100A (es)
AT (1) AT350737B (es)
AU (1) AU499926B2 (es)
BE (1) BE845563A (es)
BG (2) BG27545A3 (es)
CA (1) CA1068266A (es)
CH (5) CH622521A5 (es)
CS (2) CS192599B2 (es)
DD (1) DD127145A5 (es)
DE (1) DE2538075A1 (es)
DK (1) DK143278C (es)
ES (5) ES450897A1 (es)
FI (1) FI762430A (es)
FR (1) FR2321888A1 (es)
GB (1) GB1519719A (es)
GR (1) GR61158B (es)
HU (1) HU176929B (es)
IE (1) IE44069B1 (es)
IL (1) IL50355A (es)
LU (1) LU75667A1 (es)
MX (1) MX4133E (es)
NL (1) NL7609485A (es)
NO (1) NO145793C (es)
NZ (1) NZ181864A (es)
PH (1) PH13780A (es)
PL (2) PL110724B1 (es)
PT (1) PT65521B (es)
RO (1) RO69457A (es)
SE (1) SE7609495L (es)
SU (2) SU612631A3 (es)
YU (1) YU208176A (es)
ZA (1) ZA765120B (es)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4272541A (en) * 1978-06-02 1981-06-09 Miles Laboratories, Inc. 7,8 and 7-8 Substituted 4,5α-epoxymorphinan-6-one compounds, and methods of treating pain and drug dependence with them
US4272540A (en) * 1979-04-24 1981-06-09 Sisa, Incorporated 14-Methoxymorphinan-6-one compounds and therapeutic methods of treating pain and drug dependence with them
DE3220831A1 (de) * 1982-06-03 1983-12-08 Boehringer Ingelheim KG, 6507 Ingelheim N-(2-methoxyethyl)-noroxymorphon, dessen saeureadditionssalze, diese enthaltende arzneimittel und verfahren zu deren herstellung
US8183376B2 (en) * 2006-04-21 2012-05-22 Nektar Therapeutics Stereoselective reduction of a morphinone
NZ605234A (en) * 2010-07-08 2015-02-27 Alkermes Pharma Ireland Ltd Process for the synthesis of substituted morphinans
US9211293B2 (en) 2011-12-15 2015-12-15 Alkermes Pharma Ireland Limited Opioid agonist antagonist combinations
EP3003311A2 (en) 2013-05-24 2016-04-13 Alkermes Pharma Ireland Limited Methods for treating depressive symptoms
ES2770978T3 (es) 2013-05-24 2020-07-06 Alkermes Pharma Ireland Ltd Análogos de morfanos y morfinanos y métodos de uso
AU2019224127B2 (en) 2018-02-23 2021-12-09 Rhodes Technologies Novel opioid compounds and uses thereof
WO2022101444A1 (en) 2020-11-12 2022-05-19 Alkermes Pharma Ireland Limited Immediate release multilayer tablet

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH446370A (de) 1964-03-05 1967-11-15 Hoffmann La Roche Verfahren zur Herstellung von Phenanthren-Derivaten
DE2238839A1 (de) * 1972-08-07 1974-02-14 Boehringer Sohn Ingelheim Neue morphinon-derivate, deren saeureadditionssalze, verfahren zu ihrer herstellung sowie ihre verwendung zur herstellung von arzneimitteln

Also Published As

Publication number Publication date
NO145793B (no) 1982-02-22
ES454087A2 (es) 1977-11-16
CH624117A5 (es) 1981-07-15
AT350737B (de) 1979-06-11
ZA765120B (en) 1978-05-30
BE845563A (fr) 1977-02-28
PT65521A (de) 1976-09-01
DE2538075A1 (de) 1977-03-17
NO145793C (no) 1982-06-02
RO69457A (ro) 1981-04-30
BG27546A4 (en) 1979-11-12
GR61158B (en) 1978-09-30
US4100288A (en) 1978-07-11
PH13780A (en) 1980-09-26
CH624116A5 (es) 1981-07-15
DD127145A5 (es) 1977-09-07
NZ181864A (en) 1978-06-20
YU208176A (en) 1982-08-31
DK143278B (da) 1981-08-03
NL7609485A (nl) 1977-03-01
NO762932L (es) 1977-03-01
LU75667A1 (es) 1977-09-13
CH624115A5 (es) 1981-07-15
PT65521B (de) 1978-07-04
CH624114A5 (es) 1981-07-15
ES454086A1 (es) 1977-11-16
IE44069B1 (en) 1981-08-12
IL50355A0 (en) 1976-10-31
ATA553976A (de) 1978-11-15
ES450897A1 (es) 1977-12-01
AU1720176A (en) 1978-03-02
HU176929B (hu) 1981-06-28
IL50355A (en) 1979-11-30
MX4133E (es) 1982-01-06
BG27545A3 (en) 1979-11-12
SE7609495L (sv) 1977-02-28
IE44069L (en) 1977-02-27
FR2321888B1 (es) 1980-01-11
GB1519719A (en) 1978-08-02
FR2321888A1 (fr) 1977-03-25
CS192564B2 (en) 1979-08-31
AU499926B2 (en) 1979-05-03
CA1068266A (en) 1979-12-18
PL110724B1 (en) 1980-07-31
DK386876A (da) 1977-02-28
CH622521A5 (es) 1981-04-15
SU612631A3 (ru) 1978-06-25
ES454084A1 (es) 1977-11-16
SU638262A3 (ru) 1978-12-15
CS192599B2 (en) 1979-08-31
PL109091B1 (en) 1980-05-31
FI762430A (es) 1977-02-28
JPS5231100A (en) 1977-03-09
DK143278C (da) 1981-12-07
PL192020A1 (pl) 1979-03-12

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