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ES397400A1 - Amidoxime-o-carbamates - Google Patents

Amidoxime-o-carbamates

Info

Publication number
ES397400A1
ES397400A1 ES397400A ES397400A ES397400A1 ES 397400 A1 ES397400 A1 ES 397400A1 ES 397400 A ES397400 A ES 397400A ES 397400 A ES397400 A ES 397400A ES 397400 A1 ES397400 A1 ES 397400A1
Authority
ES
Spain
Prior art keywords
formula
carbon atoms
acid addition
addition salts
reacting
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES397400A
Other languages
Spanish (es)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
EIDP Inc
Original Assignee
EI Du Pont de Nemours and Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by EI Du Pont de Nemours and Co filed Critical EI Du Pont de Nemours and Co
Publication of ES397400A1 publication Critical patent/ES397400A1/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C271/00—Derivatives of carbamic acids, i.e. compounds containing any of the groups, the nitrogen atom not being part of nitro or nitroso groups
    • C07C271/60—Derivatives of carbamic acids, i.e. compounds containing any of the groups, the nitrogen atom not being part of nitro or nitroso groups having oxygen atoms of carbamate groups bound to nitrogen atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

Novel amidoxime o - carbamates of the Formula I wherein R is an aliphatic hydrocarbon radical having 3 to 12 carbon atoms, and each of R 1 and R 2 , which may be the same or different is H or C 1-3 alkyl, the sum of the carbon atoms in R 1 and R 2 not exceeding 3 and acid addition salts thereof are prepared by reacting amidoximes of the general Formula II with alkali metal cyanates, or with C 1-3 alkyl isocyanates of the formula or with carbamoyl halides of the formula wherein X is halogen. Pentanamidoxime is obtained by reacting valeronitrile with hydroxylamine hydrochloride. Pharmaceutical compositions, suitable for oral or parenteral administration and having antihypertensive activity, contain the above novel compounds or acid addition salts thereof, and pharmaceutically acceptable carriers or diluents.
ES397400A 1969-01-08 1971-11-26 Amidoxime-o-carbamates Expired ES397400A1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US78995969A 1969-01-08 1969-01-08
US88473769A 1969-12-12 1969-12-12

Publications (1)

Publication Number Publication Date
ES397400A1 true ES397400A1 (en) 1975-03-16

Family

ID=27120978

Family Applications (2)

Application Number Title Priority Date Filing Date
ES375236A Expired ES375236A1 (en) 1969-01-08 1970-01-07 Amidoxime-o-carbamates
ES397400A Expired ES397400A1 (en) 1969-01-08 1971-11-26 Amidoxime-o-carbamates

Family Applications Before (1)

Application Number Title Priority Date Filing Date
ES375236A Expired ES375236A1 (en) 1969-01-08 1970-01-07 Amidoxime-o-carbamates

Country Status (12)

Country Link
AR (1) AR192723A1 (en)
BE (1) BE743784A (en)
CH (1) CH534135A (en)
DE (1) DE2000492B2 (en)
DK (1) DK125390B (en)
ES (2) ES375236A1 (en)
FR (1) FR2034457B1 (en)
GB (1) GB1244592A (en)
IL (1) IL33612A (en)
LU (1) LU60149A1 (en)
NL (1) NL7000156A (en)
SE (1) SE350032B (en)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ZA731406B (en) * 1972-04-18 1974-10-30 Du Pont New antihypertensive agents
NL7908922A (en) * 1979-12-12 1981-07-16 Akzo Nv CARBOXIMIDAMIDE DERIVATIVES.

Also Published As

Publication number Publication date
FR2034457A1 (en) 1970-12-11
AR192723A1 (en) 1973-03-14
NL7000156A (en) 1970-07-10
LU60149A1 (en) 1970-03-09
IL33612A (en) 1973-06-29
DK125390B (en) 1973-02-12
DE2000492B2 (en) 1976-03-04
SE350032B (en) 1972-10-16
FR2034457B1 (en) 1973-04-06
IL33612A0 (en) 1970-03-22
BE743784A (en) 1970-05-28
GB1244592A (en) 1971-09-02
CH534135A (en) 1973-02-28
DE2000492A1 (en) 1970-07-16
ES375236A1 (en) 1972-08-01

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