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ES312384A1 - Procedure for the preparation of fenilalquilaminoguanidinas. (Machine-translation by Google Translate, not legally binding) - Google Patents

Procedure for the preparation of fenilalquilaminoguanidinas. (Machine-translation by Google Translate, not legally binding)

Info

Publication number
ES312384A1
ES312384A1 ES0312384A ES312384A ES312384A1 ES 312384 A1 ES312384 A1 ES 312384A1 ES 0312384 A ES0312384 A ES 0312384A ES 312384 A ES312384 A ES 312384A ES 312384 A1 ES312384 A1 ES 312384A1
Authority
ES
Spain
Prior art keywords
formula
addition salts
translation
preparation
well
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES0312384A
Other languages
Spanish (es)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Wander AG
Original Assignee
Wander AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Wander AG filed Critical Wander AG
Publication of ES312384A1 publication Critical patent/ES312384A1/en
Expired legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A61K31/155—Amidines (), e.g. guanidine (H2N—C(=NH)—NH2), isourea (N=C(OH)—NH2), isothiourea (—N=C(SH)—NH2)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/27—Esters, e.g. nitroglycerine, selenocyanates of carbamic or thiocarbamic acids, meprobamate, carbachol, neostigmine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C281/00—Derivatives of carbonic acid containing functional groups covered by groups C07C269/00 - C07C279/00 in which at least one nitrogen atom of these functional groups is further bound to another nitrogen atom not being part of a nitro or nitroso group
    • C07C281/16—Compounds containing any of the groups, e.g. aminoguanidine

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Epidemiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Emergency Medicine (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

Process for the preparation of phenylalkylaminoguanidines of the formula: ** (See formula) ** A straight group of alkylene with 2 or 3 C atoms and R 1 as well as R 2 are the same or different and represent hydrogen, halogen, methyl, ethyl, methoxy or ethoxy, as well as their acid addition salts, characterized in that , O well a) phenylalkylidenaminoguanidines, respectively phenylalkenylidenaminoguanidines of the formula: ** (See formula) ** A 'representing a group of alkylidene or alkenylidene corresponding to the alkylene group A, while R1 and R2 have the abovementioned meaning, respectively acid addition salts of such aminoguanidines; or why b) phenylalkylhydrazines of the formula are reacted: ** (See formula) ** having A, R1 and R2 meaning as cited above, with an S-alkyl isothiourea, respectively with an addition salt thereof; or why c) the phenylalkylhydrazines of the formula are reacted with cyanamide: ** (See formula) ** A, R 1 and R 2 having the meaning mentioned above, respectively with addition salts thereof, optionally with subsequent transformation of free bases obtained in their acid addition salts. (Machine-translation by Google Translate, not legally binding)
ES0312384A 1964-05-05 1965-04-29 Procedure for the preparation of fenilalquilaminoguanidinas. (Machine-translation by Google Translate, not legally binding) Expired ES312384A1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CH585464A CH448057A (en) 1964-05-05 1964-05-05 Process for the preparation of phenylalkylaminoguanidines

Publications (1)

Publication Number Publication Date
ES312384A1 true ES312384A1 (en) 1966-03-01

Family

ID=4300408

Family Applications (1)

Application Number Title Priority Date Filing Date
ES0312384A Expired ES312384A1 (en) 1964-05-05 1965-04-29 Procedure for the preparation of fenilalquilaminoguanidinas. (Machine-translation by Google Translate, not legally binding)

Country Status (15)

Country Link
JP (1) JPS4842627B1 (en)
AT (3) AT255432B (en)
BE (1) BE663481A (en)
BR (1) BR6569419D0 (en)
CH (3) CH448057A (en)
CS (1) CS151461B2 (en)
DE (1) DE1518222A1 (en)
DK (2) DK107288C (en)
ES (1) ES312384A1 (en)
FI (1) FI42316B (en)
FR (1) FR4399M (en)
GB (1) GB1096348A (en)
IL (1) IL23443A (en)
NL (1) NL6505684A (en)
SE (2) SE371640B (en)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR200F (en) * 1965-11-15
US3541218A (en) * 1969-06-18 1970-11-17 Lilly Co Eli Omicron-fluorobenzylaminoguanidine for diabetes
JPS5051717U (en) * 1973-09-06 1975-05-19
JPS5391735U (en) * 1976-12-27 1978-07-27
JPS54121027U (en) * 1978-02-13 1979-08-24
IL60201A (en) * 1979-06-01 1984-05-31 Wellcome Found 3-amino-6-(substituted)phenyl-1,2,4-triazine derivatives,their preparation and pharmaceutical compositions containing them
JPS5625170A (en) * 1979-06-01 1981-03-10 Wellcome Found Triazine derivative
FR2549049B1 (en) * 1983-07-13 1986-06-20 Chauvin Blache Lab NEW AMIDINES, THEIR PREPARATION PROCESS AND THEIR THERAPEUTIC APPLICATION
HU190639B (en) * 1983-12-12 1986-09-29 Gyogyszerkutato Intezet Kv,Hu Process for production of new aminoguanidin derivatives
EP0325936A3 (en) * 1988-01-16 1990-01-17 Ono Pharmaceutical Co., Ltd. Aminoguanidine derivatives and inhibitory agents on maillard reaction containing them as active ingredients
AU722161B2 (en) * 1996-03-29 2000-07-20 3-Dimensional Pharmaceuticals, Inc. Amidinohydrazones as protease inhibitors
TW499412B (en) 1996-11-26 2002-08-21 Dimensional Pharm Inc Aminoguanidines and alkoxyguanidines as protease inhibitors
MXPA03000963A (en) 2000-08-04 2004-04-05 Dimensional Pharm Inc Cyclic oxyguanidine protease inhibitors.

Also Published As

Publication number Publication date
DE1518222A1 (en) 1969-06-12
GB1096348A (en) 1967-12-29
FR4399M (en) 1966-09-05
CS151461B2 (en) 1973-10-19
IL23443A (en) 1968-09-26
BR6569419D0 (en) 1973-08-02
CH511216A (en) 1971-08-15
NL6505684A (en) 1965-11-08
CH491873A (en) 1970-06-15
DK111887B (en) 1968-10-21
SE371640B (en) 1974-11-25
SE317057B (en) 1969-11-10
AT255432B (en) 1967-07-10
DK107288C (en) 1967-05-16
AT255434B (en) 1967-07-10
BE663481A (en)
FI42316B (en) 1970-03-31
CH448057A (en) 1967-12-15
AT255433B (en) 1967-07-10
JPS4842627B1 (en) 1973-12-13

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