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ES2777200T8 - Procedimiento para la preparación de 3-aminopiperidina enriquecida enantioméricamente - Google Patents

Procedimiento para la preparación de 3-aminopiperidina enriquecida enantioméricamente

Info

Publication number
ES2777200T8
ES2777200T8 ES14705501T ES14705501T ES2777200T8 ES 2777200 T8 ES2777200 T8 ES 2777200T8 ES 14705501 T ES14705501 T ES 14705501T ES 14705501 T ES14705501 T ES 14705501T ES 2777200 T8 ES2777200 T8 ES 2777200T8
Authority
ES
Spain
Prior art keywords
aminopiperidine
procedure
preparation
enantiomerically enriched
enantiomerically
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
ES14705501T
Other languages
English (en)
Other versions
ES2777200T3 (es
Inventor
Karl Reuter
Tobias Wedel
Viktor Meier
Mark Kantor
Vasyl Andrushko
Florian Stolz
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Reuter Chemische Appbau E K
Original Assignee
Reuter Chemische Appbau E K
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Reuter Chemische Appbau E K filed Critical Reuter Chemische Appbau E K
Application granted granted Critical
Publication of ES2777200T3 publication Critical patent/ES2777200T3/es
Publication of ES2777200T8 publication Critical patent/ES2777200T8/es
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D211/00Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/06Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D211/36Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D211/56Nitrogen atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D211/00Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/06Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D211/36Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D211/60Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Hydrogenated Pyridines (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
ES14705501T 2013-02-20 2014-02-19 Procedimiento para la preparación de 3-aminopiperidina enriquecida enantioméricamente Active ES2777200T3 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP13156030 2013-02-20
PCT/EP2014/053176 WO2014128139A1 (en) 2013-02-20 2014-02-19 Process for the preparation of enantiomerically enriched 3-aminopiperidine

Publications (2)

Publication Number Publication Date
ES2777200T3 ES2777200T3 (es) 2020-08-04
ES2777200T8 true ES2777200T8 (es) 2020-09-29

Family

ID=47748496

Family Applications (1)

Application Number Title Priority Date Filing Date
ES14705501T Active ES2777200T3 (es) 2013-02-20 2014-02-19 Procedimiento para la preparación de 3-aminopiperidina enriquecida enantioméricamente

Country Status (14)

Country Link
US (3) US10464898B2 (es)
EP (3) EP3653607B1 (es)
JP (2) JP6370316B2 (es)
KR (1) KR102236806B1 (es)
CN (1) CN105102430A (es)
DK (1) DK2958894T3 (es)
ES (1) ES2777200T3 (es)
HR (1) HRP20200437T1 (es)
HU (1) HUE048567T2 (es)
IL (1) IL240214B (es)
PL (1) PL2958894T3 (es)
PT (1) PT2958894T (es)
SI (1) SI2958894T1 (es)
WO (1) WO2014128139A1 (es)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SI2958894T1 (sl) 2013-02-20 2020-07-31 Reuter Chemische Apparatebau E.K. Proces za pripravo enatiomerno obogatenega 3 aminopiperidina
CN108693272B (zh) * 2018-06-04 2021-03-12 吉林百纯化学科技有限公司 一种hplc法分析及制备n-(对甲苯磺酰基)-l-丙氨酸及其对映异构体的方法
CN109668987A (zh) * 2019-02-27 2019-04-23 浙江华贝药业有限责任公司 一种3-氨基哌啶二盐酸盐对映异构体测定分析方法
CN110078657A (zh) * 2019-04-10 2019-08-02 湖州复华春生物医药科技有限公司 一种手性3-氨基哌啶及其衍生物的合成方法
CN115825297A (zh) * 2022-11-11 2023-03-21 武汉海特生物创新医药研究有限公司 一种(s)-3-氨基哌啶-2,6-二酮盐酸盐对映异构体的检测方法

Family Cites Families (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE1024974B (de) 1956-10-17 1958-02-27 Dr Alfred Dornow Verfahren zur Herstellung von 2-Oxy-7-aza-benzimidazolen
US5334766A (en) 1991-04-29 1994-08-02 Hoffmann-La Roche Inc. Process for the resolution of racemic diphosphine oxides
US5220016A (en) 1991-07-29 1993-06-15 Board Of Regents, The University Of Texas System Synthesis of navelbine analogs
JP3716376B2 (ja) * 1995-10-26 2005-11-16 東レ・ファインケミカル株式会社 光学分割剤およびそれを用いた光学活性3−アミノピロリジン誘導体の製造法
ATE220939T1 (de) 1996-03-10 2002-08-15 Reuter Chemischer Appbau Kg Trennverfahren
US6515130B1 (en) 1999-03-22 2003-02-04 Judith H. Cohen Process for preparing [S-(R*,S*)]-β-[[[1-[1-oxo-3(4-piperidinyl)propyl]-3-piperidinyl]carbonyl]amino]-3-pyridinepropanoic acid and derivatives
AU781747B2 (en) * 1999-10-08 2005-06-09 Meiji Seika Kaisha Ltd. 3-aminopiperidine derivatives as integrin alphavbeta3 antagonists
WO2001068604A2 (en) 2000-03-14 2001-09-20 Sepracor, Inc. 3-substituted piperidines comprising urea functionality, and methods of use thereof
EP1146029A1 (en) 2000-04-13 2001-10-17 Nissan Chemical Industries Ltd. Method for optical resolution of piperidine carboxylic acid derivative
EP1341762A1 (en) 2000-11-20 2003-09-10 Eli Lilly And Company Process for resolving racemic mixtures of piperidine derivatives
GB0126859D0 (en) 2001-11-08 2002-01-02 Kee Klamp Ltd Counter-balance weight for a modular safety rail
WO2007075630A1 (en) 2005-12-22 2007-07-05 Dow Global Technologies Inc. Method for producing 3-aminopiperidine diastereomer
ITMI20060179A1 (it) 2006-02-02 2007-08-03 Abiogen Pharma Spa Procedimento per la risoluzione di miscele racemiche e complesso diastereoisomerico di un agente risolvente e di unantiomero di interesse
EP1999108A1 (en) * 2006-03-28 2008-12-10 Takeda Pharmaceutical Company Limited Preparation of (r)-3-aminopiperidine dihydrochloride
WO2008102720A1 (ja) 2007-02-19 2008-08-28 Kaneka Corporation 光学活性3-アミノピペリジン又はその塩の製造方法
US20100331546A1 (en) 2008-02-27 2010-12-30 Sumitomo Chemical Company, Limited Method for optical resolution of alkyl piperidin-3-yl carbamate and intermediate therefor
CN101565397B (zh) * 2009-04-07 2011-08-10 浙江医药股份有限公司新昌制药厂 N-Boc-3-氨基哌啶及其光学异构体的合成方法
JP2011012032A (ja) 2009-07-03 2011-01-20 Yamakawa Yakuhin Kogyo Kk 光学活性な3−アミノピペリジンの製造方法および製造の中間体
JP5585822B2 (ja) 2010-05-11 2014-09-10 東レ・ファインケミカル株式会社 光学活性ニペコチン酸誘導体の製造方法
EP2582671A4 (en) * 2010-06-17 2014-02-26 Reddys Lab Ltd Dr PROCESS FOR PREPARING A SINGLE ENANTIOMER FROM 3-AMINOPIPERIDIN DIHYDROCHLORIDE
SI2958894T1 (sl) 2013-02-20 2020-07-31 Reuter Chemische Apparatebau E.K. Proces za pripravo enatiomerno obogatenega 3 aminopiperidina

Also Published As

Publication number Publication date
DK2958894T3 (da) 2020-03-23
IL240214A0 (en) 2015-09-24
EP3653607C0 (en) 2023-10-18
US11897843B2 (en) 2024-02-13
IL240214B (en) 2018-02-28
JP2018168194A (ja) 2018-11-01
EP4289819A2 (en) 2023-12-13
EP3653607B1 (en) 2023-10-18
SI2958894T1 (sl) 2020-07-31
US20160251311A1 (en) 2016-09-01
KR20150123267A (ko) 2015-11-03
EP2958894B8 (en) 2020-02-26
US11472770B2 (en) 2022-10-18
JP6370316B2 (ja) 2018-08-08
JP6580218B2 (ja) 2019-09-25
EP4289819A3 (en) 2024-01-10
EP2958894B1 (en) 2019-12-18
US20200087257A1 (en) 2020-03-19
EP2958894A1 (en) 2015-12-30
EP3653607A2 (en) 2020-05-20
PL2958894T3 (pl) 2020-06-29
EP3653607A3 (en) 2020-07-29
CN105102430A (zh) 2015-11-25
KR102236806B1 (ko) 2021-04-06
WO2014128139A1 (en) 2014-08-28
HRP20200437T1 (hr) 2020-09-04
US20230008387A1 (en) 2023-01-12
HUE048567T2 (hu) 2020-07-28
ES2777200T3 (es) 2020-08-04
US10464898B2 (en) 2019-11-05
PT2958894T (pt) 2020-03-10
JP2016508514A (ja) 2016-03-22

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