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ES2121794T3 - Procedimiento de transferencia de genes por medio de retrotransposones. - Google Patents

Procedimiento de transferencia de genes por medio de retrotransposones.

Info

Publication number
ES2121794T3
ES2121794T3 ES91920651T ES91920651T ES2121794T3 ES 2121794 T3 ES2121794 T3 ES 2121794T3 ES 91920651 T ES91920651 T ES 91920651T ES 91920651 T ES91920651 T ES 91920651T ES 2121794 T3 ES2121794 T3 ES 2121794T3
Authority
ES
Spain
Prior art keywords
gene
retrotransposons
hybrid
gene transfer
transfer procedure
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES91920651T
Other languages
English (en)
Inventor
Clague Pitman Hodgson
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Individual
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Application granted granted Critical
Publication of ES2121794T3 publication Critical patent/ES2121794T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2800/00—Nucleic acids vectors
    • C12N2800/90—Vectors containing a transposable element
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2830/00—Vector systems having a special element relevant for transcription
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2830/00—Vector systems having a special element relevant for transcription
    • C12N2830/80—Vector systems having a special element relevant for transcription from vertebrates
    • C12N2830/85—Vector systems having a special element relevant for transcription from vertebrates mammalian

Landscapes

  • Genetics & Genomics (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Organic Chemistry (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Molecular Biology (AREA)
  • Microbiology (AREA)
  • Plant Pathology (AREA)
  • Physics & Mathematics (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Biophysics (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Valve Device For Special Equipments (AREA)

Abstract

METODO DE INTERCAMBIO DE GENES UTILIZANDO RETROTRANSPOSONOS. SE INVENTA UN PROCESO PARA EL INTERCAMBIO Y/O EXTRACCION DE CUALQUIER GEN EN CELULAS, ORGANISMOS O ESPECIES. EL PROCESO INCLUYE EL AISLAMIENTO DEL GEN, LA INTRODUCCION DEL GEN EN UN VECTOR COMPUESTO DE AL MENOS UN ELEMENTO GENETICO DE RETROTRANSPOSONA PARA PROPORCIONAR UN GEN HIBRIDO. EL GEN HIBRIDO SE INTRODUCE EN UNA CELULA DONANTE CAPAZ DE EMPAQUETAR Y TRANSMITIR EL RETROTRANSPOSON A OTRAS CELULAS, ORGANISMO O ESPECIES. EL GEN HIBRIDO SE TRASPASA A UNA CELULA RECEPTORA DONDE EL GEN HIBRIDO HACE UNA REPLICA POR TRANSCRIPCION INVERSA Y SE INSERTA EN EL GENOMIO DE LA CELULA RECEPTORA. EL GEN SE EXPRESA PREFERIBLEMENTE COMO RNA Y/O PROTEINA, DANDO EL FENOTIPO DEL GEN.
ES91920651T 1990-10-25 1991-10-25 Procedimiento de transferencia de genes por medio de retrotransposones. Expired - Lifetime ES2121794T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US60363590A 1990-10-25 1990-10-25

Publications (1)

Publication Number Publication Date
ES2121794T3 true ES2121794T3 (es) 1998-12-16

Family

ID=24416288

Family Applications (1)

Application Number Title Priority Date Filing Date
ES91920651T Expired - Lifetime ES2121794T3 (es) 1990-10-25 1991-10-25 Procedimiento de transferencia de genes por medio de retrotransposones.

Country Status (9)

Country Link
US (2) US5354674A (es)
EP (1) EP0506945B1 (es)
JP (1) JPH05503636A (es)
AT (1) ATE169061T1 (es)
CA (1) CA2072581A1 (es)
DE (1) DE69129897T2 (es)
DK (1) DK0506945T3 (es)
ES (1) ES2121794T3 (es)
WO (1) WO1992007950A1 (es)

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CA2042093C (en) * 1990-05-09 2002-12-24 Gyula Hadlaczky Cell line carrying an excess of mammalian centromeres
US6027722A (en) * 1990-10-25 2000-02-22 Nature Technology Corporation Vectors for gene transfer
ES2121794T3 (es) * 1990-10-25 1998-12-16 Clague Pitman Hodgson Procedimiento de transferencia de genes por medio de retrotransposones.
JP3533219B2 (ja) * 1992-11-09 2004-05-31 アメリカ合衆国 標的指向ベクター粒子
CA2157931A1 (en) 1993-03-12 1994-09-15 Clague P. Hodgson Improved vectors for gene therapy
US6340674B1 (en) 1993-03-26 2002-01-22 Thomas Jefferson University Method of inhibiting the proliferation and causing the differentiation of cells with IGF-1 receptor antisense oligonucleotides
FR2703996B1 (fr) * 1993-04-16 1995-07-21 Transgene Sa Ensemble de transposition destine au transfert d'un gene d'interet dans le genome d'une cellule eucaryote.
FR2722208B1 (fr) * 1994-07-05 1996-10-04 Inst Nat Sante Rech Med Nouveau site interne d'entree des ribosomes, vecteur le contenant et utilisation therapeutique
US5714170A (en) 1994-11-16 1998-02-03 Thomas Jefferson University Method of inducing resistance to tumor growth
US6254862B1 (en) 1997-03-03 2001-07-03 Calydon, Inc. Adenovirus vectors specific for cells expressing alpha-fetoprotein and methods of use thereof
US7011976B1 (en) 1997-03-03 2006-03-14 Calydon, Inc. Adenovirus vectors specific for cells expressing alpha-fetoprotein and methods of use thereof
US20030190753A1 (en) * 1995-11-09 2003-10-09 Nature Technology Corporation Vectors for gene transfer
EP0861267A4 (en) * 1995-11-14 2000-02-02 Univ Jefferson INDUCTION AND RESISTANCE TO TUMOR GROWTH BY MEANS OF SOLUBLE IGF-1
US5837464A (en) * 1996-01-29 1998-11-17 Virologic, Inc. Compositions and methods for determining anti-viral drug susceptibility and resistance and anti-viral drug screening
US6242187B1 (en) * 1996-01-29 2001-06-05 Virologic, Inc. Compositions and methods for determining anti-viral drug susceptibility and resistance and anti-viral drug screening
US6077697A (en) 1996-04-10 2000-06-20 Chromos Molecular Systems, Inc. Artificial chromosomes, uses thereof and methods for preparing artificial chromosomes
US20030033617A1 (en) * 1996-04-10 2003-02-13 Gyula Hadlaczky Artificial chromosomes, uses thereof and methods for preparing artificial chromosomes
US20020160970A1 (en) * 1996-04-10 2002-10-31 Gyula Hadlaczky Artificial chromosomes, uses thereof and methods for preparing artificial chromosomes
US6025155A (en) * 1996-04-10 2000-02-15 Chromos Molecular Systems, Inc. Artificial chromosomes, uses thereof and methods for preparing artificial chromosomes
US5928888A (en) * 1996-09-26 1999-07-27 Aurora Biosciences Corporation Methods and compositions for sensitive and rapid, functional identification of genomic polynucleotides and secondary screening capabilities
AU6443298A (en) 1997-02-28 1998-09-18 Nature Technology Corporation Self-assembling genes, vectors and uses thereof
JP2002511741A (ja) 1997-03-11 2002-04-16 リージェンツ オブ ザ ユニバーシティ オブ ミネソタ 細胞のｄｎａに核酸を導入するためのｄｎａ系トランスポゾンシステム
CA2285937C (en) 1997-04-10 2010-12-14 Frederick L. Hall Modified proteins which bind extracellular matrix components
US6541036B1 (en) 1997-05-29 2003-04-01 Thomas Jefferson University Treatment of tumors with oligonucleotides directed to insulin-like growth factor-I receptors (IGF-IR)
US20020034732A1 (en) * 1997-07-30 2002-03-21 Daniel J. Capon Compositions and methods for determining anti-viral drug susceptibility and resistance and anti-viral drug screening
DE69838584T2 (de) 1997-08-04 2008-06-26 Cell Genesys, Inc., Foster City Enhancer des menschlichen glandulären kallikreingens, vektoren die ihn enthalten und methoden für seine verwendung
US8563803B2 (en) * 1997-10-16 2013-10-22 Synageva Biopharma Corp. Method of making protein in an egg of a transgenic chicken
US7129390B2 (en) 1997-10-16 2006-10-31 Avigenics, Inc Poultry Derived Glycosylated Interferon Alpha 2b
EP2133421A1 (en) * 1997-10-16 2009-12-16 University Of Georgia Research Foundation, Inc. Transgenic birds and protein production in the egg white
US20040019923A1 (en) * 1997-10-16 2004-01-29 Ivarie Robert D. Exogenous proteins expressed in avians and their eggs
WO1999025862A2 (en) * 1997-11-19 1999-05-27 Nature Technology, Inc. Chimeric viral packaging signal without gag gene sequences
US7078483B2 (en) * 1998-04-29 2006-07-18 University Of Southern California Retroviral vectors including modified envelope escort proteins
US20060292121A1 (en) * 1998-04-29 2006-12-28 Hall Frederick L Retroviral vectors including modified envelope escort protein
US7160682B2 (en) * 1998-11-13 2007-01-09 Regents Of The University Of Minnesota Nucleic acid transfer vector for the introduction of nucleic acid into the DNA of a cell
ES2343106T3 (es) * 2000-09-28 2010-07-23 BIORIGINAL FOOD & SCIENCE CORP. Fad4, fad5, fad5-2 y fad6, miembros de la familia de desaturasas de acidos grasos y usos de los mismos.
AU2002236517A1 (en) * 2000-11-29 2002-06-11 University Of Southern California Targetet retoviral vectors for cancer immunotherapy
DE60044301D1 (de) 2000-12-22 2010-06-10 Agronomique Inst Nat Rech Positionsunabhängige und gewebespezifische Expression eines Transgens in der Milch eines Transgen-Tieres
AU2003231048A1 (en) * 2002-04-22 2003-11-03 Regents Of The University Of Minnesota Transposon system and methods of use
US20070037759A1 (en) * 2003-02-07 2007-02-15 Administrators Of The Tulane Educational Fund, The Mammalian retrotransposable elements
US20070178066A1 (en) * 2003-04-21 2007-08-02 Hall Frederick L Pathotropic targeted gene delivery system for cancer and other disorders
EP2353389B1 (en) * 2003-04-21 2015-11-04 Epeius Biotechnologies Corporation Compositions for treating disorders
US20090123428A1 (en) * 2003-04-21 2009-05-14 Hall Frederick L Pathotropic targeted gene delivery system for cancer and other disorders
US20040219099A1 (en) * 2003-05-02 2004-11-04 Jasbir Sandhu Method for the treatment of tumors
US20040220085A1 (en) * 2003-05-02 2004-11-04 Jasbir Sandhu Compositions for nucleic acid delivery
US20060026699A1 (en) * 2004-06-04 2006-02-02 Largaespada David A Methods and compositions for identification of genomic sequences
AU2007345347B2 (en) * 2007-01-26 2013-11-07 Synageva Biopharma Corp Transgene expression in avians
EP2441831B9 (en) * 2009-06-11 2019-03-06 Inter-University Research Institute Corporation Research Organization of Information and Systems Process for production of protein
CN103548775B (zh) * 2013-10-23 2015-03-18 中国科学院武汉病毒研究所 一种cd81和ocln双转基因小鼠的构建方法和用途

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US4719177A (en) * 1981-04-20 1988-01-12 Massachusetts Institute Of Technology Production of complementary DNA representing RNA viral sequences by recombinant DNA methods and uses therefor
US4873191A (en) * 1981-06-12 1989-10-10 Ohio University Genetic transformation of zygotes
US4405712A (en) * 1981-07-01 1983-09-20 The United States Of America As Represented By The Department Of Health And Human Services LTR-Vectors
AU560472B2 (en) * 1981-08-25 1987-04-09 Celltech Limited Yeast expression vectors
US4670388A (en) * 1982-12-30 1987-06-02 Carnegie Institution Of Washington Method of incorporating DNA into genome of drosophila
US4650764A (en) * 1983-04-12 1987-03-17 Wisconsin Alumni Research Foundation Helper cell
GB8314961D0 (en) * 1983-05-31 1983-07-06 Kingsman A J Dna sequence
US4686098A (en) * 1984-05-14 1987-08-11 Merck & Co., Inc. Encapsulated mouse cells transformed with avian retrovirus-bovine growth hormone DNA, and a method of administering BGH in vivo
US4828987A (en) * 1984-05-14 1989-05-09 Merck & Co., Inc. Avian retrovirus-bovine growth hormone DNA
FR2571737B1 (fr) * 1984-10-15 1987-02-20 Agronomique Inst Nat Rech Vecteurs de clonage ou d'expression comportant le genome du virus de l'erythroblastose aviaire et cellules transfectees par ces vecteurs
AU6131086A (en) * 1985-07-05 1987-01-30 Whitehead Institute For Biomedical Research Epithelial cells expressing foreign genetic material
US4861719A (en) * 1986-04-25 1989-08-29 Fred Hutchinson Cancer Research Center DNA constructs for retrovirus packaging cell lines
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US4918166A (en) * 1987-04-10 1990-04-17 Oxford Gene Systems Limited Particulate hybrid HIV antigens
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ES2121794T3 (es) * 1990-10-25 1998-12-16 Clague Pitman Hodgson Procedimiento de transferencia de genes por medio de retrotransposones.

Also Published As

Publication number Publication date
EP0506945B1 (en) 1998-07-29
WO1992007950A1 (en) 1992-05-14
US5354674A (en) 1994-10-11
JPH05503636A (ja) 1993-06-17
DE69129897D1 (de) 1998-09-03
DK0506945T3 (da) 1999-04-26
US5879933A (en) 1999-03-09
DE69129897T2 (de) 1998-12-17
EP0506945A4 (en) 1993-04-28
CA2072581A1 (en) 1992-04-26
ATE169061T1 (de) 1998-08-15
EP0506945A1 (en) 1992-10-07

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