ES2179523T3 - Metodo para aumentar la biodisponibilidad de la fexofenadina y sus derivados. - Google Patents
Metodo para aumentar la biodisponibilidad de la fexofenadina y sus derivados.Info
- Publication number
- ES2179523T3 ES2179523T3 ES98935892T ES98935892T ES2179523T3 ES 2179523 T3 ES2179523 T3 ES 2179523T3 ES 98935892 T ES98935892 T ES 98935892T ES 98935892 T ES98935892 T ES 98935892T ES 2179523 T3 ES2179523 T3 ES 2179523T3
- Authority
- ES
- Spain
- Prior art keywords
- antihistamine
- biodisponibility
- fexofenadine
- derivatives
- increase
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/74—Synthetic polymeric materials
- A61K31/745—Polymers of hydrocarbons
- A61K31/75—Polymers of hydrocarbons of ethene
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
- A61K47/42—Proteins; Polypeptides; Degradation products thereof; Derivatives thereof, e.g. albumin, gelatin or zein
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/445—Non condensed piperidines, e.g. piperocaine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/74—Synthetic polymeric materials
- A61K31/765—Polymers containing oxygen
- A61K31/77—Polymers containing oxygen of oxiranes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Epidemiology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Pulmonology (AREA)
- Immunology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Inorganic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Saccharide Compounds (AREA)
Abstract
Una combinación para mejorar la biodisponibilidad de una antihistamina de piperidinoalcanol de la siguiente fórmula I en la que R es hidrógeno o un grupo alquilo de C1-C6, o una de sus sales farmacéuticamente aceptables o de sus isómeros ópticos individuales, que comprende una cantidad antihistamínica efectiva de dicha antihistamina de piperidinoalcanol y un cantidad efectiva inhibidora de la p-glicoproteína de un inhibidor de p-glicoproteína, en una forma de dosificación adecuada para administración conjunta.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US91156397A | 1997-08-14 | 1997-08-14 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES2179523T3 true ES2179523T3 (es) | 2003-01-16 |
Family
ID=25430473
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES98935892T Expired - Lifetime ES2179523T3 (es) | 1997-08-14 | 1998-07-21 | Metodo para aumentar la biodisponibilidad de la fexofenadina y sus derivados. |
Country Status (30)
| Country | Link |
|---|---|
| EP (1) | EP1003528B1 (es) |
| JP (1) | JP4295913B2 (es) |
| KR (1) | KR100522985B1 (es) |
| CN (1) | CN1143680C (es) |
| AR (1) | AR018505A1 (es) |
| AT (1) | ATE224721T1 (es) |
| AU (1) | AU725965C (es) |
| BR (1) | BR9811937A (es) |
| CA (1) | CA2301267C (es) |
| CZ (1) | CZ293666B6 (es) |
| DE (1) | DE69808303T2 (es) |
| DK (1) | DK1003528T3 (es) |
| EE (1) | EE04263B1 (es) |
| ES (1) | ES2179523T3 (es) |
| HK (1) | HK1025901A1 (es) |
| HU (1) | HU226823B1 (es) |
| ID (1) | ID24463A (es) |
| IL (1) | IL134521A (es) |
| NO (1) | NO325148B1 (es) |
| NZ (1) | NZ502133A (es) |
| OA (1) | OA11287A (es) |
| PL (1) | PL191607B1 (es) |
| PT (1) | PT1003528E (es) |
| RU (1) | RU2197967C2 (es) |
| SK (1) | SK283868B6 (es) |
| TR (1) | TR200000419T2 (es) |
| TW (1) | TWI240633B (es) |
| UA (1) | UA64765C2 (es) |
| WO (1) | WO1999008690A1 (es) |
| ZA (1) | ZA987221B (es) |
Families Citing this family (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ES2181868T3 (es) * | 1995-02-28 | 2003-03-01 | Aventis Pharma Inc | Composicion farmaceutica para compuestos de piperidinoalcanol. |
| CZ295461B6 (cs) * | 1997-08-26 | 2005-08-17 | Aventis Pharmaceuticals Inc. | Farmaceutický prostředek ve formě dvouvrstvé tablety |
| GB9822170D0 (en) * | 1998-10-13 | 1998-12-02 | Danbioyst Uk Ltd | Novel formulations of fexofenadine |
| WO2003101437A2 (en) * | 2002-05-29 | 2003-12-11 | Aventis Pharmaceuticals Holdings Inc. | Method of treating asthma using fexofenadine |
| JP2008120684A (ja) * | 2005-03-07 | 2008-05-29 | Kumamoto Univ | 抗アレルギー薬 |
| KR101106374B1 (ko) | 2009-06-05 | 2012-01-19 | 민병욱 | 고체연료에 의한 가연성 가스 발생 장치 |
| KR101117014B1 (ko) * | 2009-09-09 | 2012-06-14 | 민병욱 | 부패성 폐기물의 바이오매스 처리에 의한 폐자원 재활용 방법 및 장치 |
| CN101843616B (zh) * | 2010-06-04 | 2011-07-27 | 西安万隆制药有限责任公司 | 一种盐酸非索非那定与微晶纤维素组合物及其制备方法 |
| RU2453315C2 (ru) * | 2010-08-17 | 2012-06-20 | Открытое акционерное общество "Химико-фармацевтический комбинат "АКРИХИН" (ОАО "АКРИХИН") | Фармацевтическая композиция для лечения аллергических заболеваний |
| CA2835912A1 (en) | 2011-05-20 | 2012-11-29 | Aventis Pharmaceuticals Inc. | Pharmaceutical composition comprising fexofenadine |
| RU2504018C1 (ru) * | 2012-05-28 | 2014-01-10 | Государственное бюджетное образовательное учреждение высшего профессионального образования "Рязанский государственный медицинский университет имени академика И.П. Павлова" Министерства здравоохранения и социального развития Российской Федерации | Способ моделирования состояния индукции функциональной активности гликопротеина-р финастеридом в эксперименте |
| RU2553362C1 (ru) * | 2014-01-09 | 2015-06-10 | Государственное бюджетное образовательное учреждение высшего профессионального образования "Рязанский государственный медицинский университет имени академика И.П. Павлова" Министерства здравоохранения Российской Федерации | Способ моделирования состояния ингибирования функциональной активности гликопротеина-р линестренолом в эксперименте |
| CN104188998A (zh) * | 2014-09-18 | 2014-12-10 | 中山大学 | 一种柚皮苷与盐酸非索非那丁药物组合物及其制剂 |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5567592A (en) * | 1994-02-02 | 1996-10-22 | Regents Of The University Of California | Screening method for the identification of bioenhancers through the inhibition of P-glycoprotein transport in the gut of a mammal |
| JPH11507356A (ja) * | 1995-06-07 | 1999-06-29 | アブマックス，インコーポレイティド | 経口薬理化合物の生物有用性を高めるためのエッセンシャルオイルの利用 |
| WO1996040792A1 (en) * | 1995-06-07 | 1996-12-19 | Novo Nordisk A/S | Modification of polypeptides |
-
1998
- 1998-07-21 EP EP98935892A patent/EP1003528B1/en not_active Expired - Lifetime
- 1998-07-21 HU HU0003189A patent/HU226823B1/hu unknown
- 1998-07-21 RU RU2000106042/14A patent/RU2197967C2/ru active
- 1998-07-21 BR BR9811937-0A patent/BR9811937A/pt not_active Application Discontinuation
- 1998-07-21 CA CA002301267A patent/CA2301267C/en not_active Expired - Lifetime
- 1998-07-21 WO PCT/US1998/015098 patent/WO1999008690A1/en active IP Right Grant
- 1998-07-21 NZ NZ502133A patent/NZ502133A/xx not_active IP Right Cessation
- 1998-07-21 DE DE69808303T patent/DE69808303T2/de not_active Expired - Lifetime
- 1998-07-21 IL IL13452198A patent/IL134521A/xx not_active IP Right Cessation
- 1998-07-21 CN CNB988081598A patent/CN1143680C/zh not_active Expired - Lifetime
- 1998-07-21 TR TR2000/00419T patent/TR200000419T2/xx unknown
- 1998-07-21 CZ CZ2000522A patent/CZ293666B6/cs not_active IP Right Cessation
- 1998-07-21 PT PT98935892T patent/PT1003528E/pt unknown
- 1998-07-21 JP JP2000509429A patent/JP4295913B2/ja not_active Expired - Lifetime
- 1998-07-21 EE EEP200000069A patent/EE04263B1/xx unknown
- 1998-07-21 SK SK184-2000A patent/SK283868B6/sk not_active IP Right Cessation
- 1998-07-21 KR KR10-2000-7001447A patent/KR100522985B1/ko not_active IP Right Cessation
- 1998-07-21 ID IDW20000262A patent/ID24463A/id unknown
- 1998-07-21 AT AT98935892T patent/ATE224721T1/de active
- 1998-07-21 PL PL338579A patent/PL191607B1/pl unknown
- 1998-07-21 AU AU85050/98A patent/AU725965C/en not_active Expired
- 1998-07-21 UA UA2000031425A patent/UA64765C2/uk unknown
- 1998-07-21 DK DK98935892T patent/DK1003528T3/da active
- 1998-07-21 ES ES98935892T patent/ES2179523T3/es not_active Expired - Lifetime
- 1998-08-12 ZA ZA987221A patent/ZA987221B/xx unknown
- 1998-08-13 AR ARP980104005A patent/AR018505A1/es active IP Right Grant
- 1998-11-05 TW TW087113210A patent/TWI240633B/zh not_active IP Right Cessation
-
2000
- 2000-02-09 OA OA1200000032A patent/OA11287A/en unknown
- 2000-02-11 NO NO20000706A patent/NO325148B1/no not_active IP Right Cessation
- 2000-08-15 HK HK00105070A patent/HK1025901A1/xx not_active IP Right Cessation
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