[go: up one dir, main page]
More Web Proxy on the site http://driver.im/

GT199900148A - Desnaturalizantes para las sales aminas simpaticomimeticas. - Google Patents

Desnaturalizantes para las sales aminas simpaticomimeticas.

Info

Publication number
GT199900148A
GT199900148A GT199900148A GT199900148A GT199900148A GT 199900148 A GT199900148 A GT 199900148A GT 199900148 A GT199900148 A GT 199900148A GT 199900148 A GT199900148 A GT 199900148A GT 199900148 A GT199900148 A GT 199900148A
Authority
GT
Guatemala
Prior art keywords
composition
combination
products
amine
present
Prior art date
Application number
GT199900148A
Other languages
English (en)
Inventor
William S Bess
Wiliam Michael Nichols
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed filed Critical
Publication of GT199900148A publication Critical patent/GT199900148A/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/205—Amine addition salts of organic acids; Inner quaternary ammonium salts, e.g. betaine, carnitine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
    • A61K31/137—Arylalkylamines, e.g. amphetamine, epinephrine, salbutamol, ephedrine or methadone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/74—Synthetic polymeric materials
    • A61K31/765—Polymers containing oxygen
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/141—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers
    • A61K9/146—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers with organic macromolecular compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1629—Organic macromolecular compounds
    • A61K9/1652—Polysaccharides, e.g. alginate, cellulose derivatives; Cyclodextrin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
    • A61K9/2077—Tablets comprising drug-containing microparticles in a substantial amount of supporting matrix; Multiparticulate tablets
    • A61K9/2081—Tablets comprising drug-containing microparticles in a substantial amount of supporting matrix; Multiparticulate tablets with microcapsules or coated microparticles according to A61K9/50
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Emergency Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Psychiatry (AREA)
  • Cardiology (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

LA PRESENTE INVENCION SE REFIERE A COMPOSICIONES FARMACEUTICAS QUE COMPRENDEN UNA SAL AMINA SIMPATICOMIMETICA Y AL MENOS UN INHIBIDOR DE COMBINACION, EL INHIBIDOR DE COMBINACION QUE ACTUA TANTO PARA INTERFERIR CON EL AISLAMIENTO DE LA AMINA SIMPATICOMIMETICA DE LA COMPOSICION COMO PARA INTERFERIR CON LA CONVERSION DE LA AMINA SIMPATICOMIMETICA CON OTRO COMPUESTO FARMACOLOGICAMENTE ACTIVO. ESTAS SALES SON AMPLIAMENTE USADOS EN PRODUCTOS FARMACEUTICOS CON VENTA LIBRE DE TAL MANERA QUE SON MATERIA PRIMA PARA LA TRANSFORMACION EN OTROS COMPUESTOS ESTIMULANTES DEL SNC; EL OBJETIVO DE LA PRESENTE INVENCION ES DISUADIR SIGNIFICATIVAMENTE EL USO DE LOS PRODUCTOS DE VENTA LIBRE EN LAS PREPARACIONES ILICITAS DE DROGAS SIN COMPROMETER EL ACCESO DE ESTOS PRODUCTOS A TODAS LAS PERSONAS. LA PRESENCIA DE LOS INHIBIDORES DE COMBINACION, REACCION Y SEPARACION NO ALTERA DE MANERA SIGNIFICATIVA LA LIBERACION DE LA AMINA SIMPATICOMIMETICA DE LA COMPOSICION.
GT199900148A 1998-09-10 1999-09-07 Desnaturalizantes para las sales aminas simpaticomimeticas. GT199900148A (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US9971298P 1998-09-10 1998-09-10

Publications (1)

Publication Number Publication Date
GT199900148A true GT199900148A (es) 2001-02-28

Family

ID=22276270

Family Applications (1)

Application Number Title Priority Date Filing Date
GT199900148A GT199900148A (es) 1998-09-10 1999-09-07 Desnaturalizantes para las sales aminas simpaticomimeticas.

Country Status (22)

Country Link
US (4) US6359011B1 (es)
EP (1) EP1112089A1 (es)
JP (1) JP2002524534A (es)
KR (1) KR20010075021A (es)
CN (1) CN1201822C (es)
AR (1) AR032730A1 (es)
AU (2) AU771194B2 (es)
BR (1) BR9913575A (es)
CA (1) CA2339354A1 (es)
CO (1) CO5280050A1 (es)
CR (1) CR6106A (es)
GT (1) GT199900148A (es)
HK (1) HK1039898A1 (es)
HN (1) HN1999000156A (es)
MY (1) MY117971A (es)
NZ (1) NZ510012A (es)
PA (1) PA8481601A1 (es)
PE (1) PE20001034A1 (es)
SV (1) SV1999000148A (es)
TW (1) TW550071B (es)
UY (1) UY25702A1 (es)
WO (1) WO2000015261A1 (es)

Families Citing this family (32)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GT199900148A (es) * 1998-09-10 2001-02-28 Desnaturalizantes para las sales aminas simpaticomimeticas.
JP3563070B2 (ja) * 2000-07-17 2004-09-08 山之内製薬株式会社 経口吸収改善医薬組成物
EP2283817B1 (en) * 2000-11-30 2016-05-18 Vectura Limited Method of making particles for use in a pharmaceutical composition
ITMI20021074A1 (it) * 2002-05-20 2003-11-20 Actimex S R L Composizione ternaria comprendente una sostanza attiva e processo di comacinazione per la sua preparazione
US7776314B2 (en) 2002-06-17 2010-08-17 Grunenthal Gmbh Abuse-proofed dosage system
DE102005005446A1 (de) 2005-02-04 2006-08-10 Grünenthal GmbH Bruchfeste Darreichungsformen mit retardierter Freisetzung
DE10361596A1 (de) 2003-12-24 2005-09-29 Grünenthal GmbH Verfahren zur Herstellung einer gegen Missbrauch gesicherten Darreichungsform
US7201920B2 (en) 2003-11-26 2007-04-10 Acura Pharmaceuticals, Inc. Methods and compositions for deterring abuse of opioid containing dosage forms
US20050220877A1 (en) * 2004-03-31 2005-10-06 Patel Ashish A Bilayer tablet comprising an antihistamine and a decongestant
DE102004032049A1 (de) 2004-07-01 2006-01-19 Grünenthal GmbH Gegen Missbrauch gesicherte, orale Darreichungsform
DE102004045037A1 (de) * 2004-09-15 2006-03-16 Basf Ag Pharmazeutische Darreichungsformen mit erschwerter Extrahierbarkeit eines Sympathomimetikums aus der Darreichungsform
DE102005005449A1 (de) 2005-02-04 2006-08-10 Grünenthal GmbH Verfahren zur Herstellung einer gegen Missbrauch gesicherten Darreichungsform
JP5249050B2 (ja) * 2006-01-19 2013-07-31 ダウ グローバル テクノロジーズ エルエルシー エチルセルロースを含む生物活性組成物
US9238073B2 (en) * 2006-04-12 2016-01-19 Wyeth Llc Pharmaceutical composition containing sympathomimetic amine salt and co-distillable additive
ES2612032T3 (es) * 2007-06-04 2017-05-11 Shear/Kershman Laboratories, Inc. Formas farmacéuticas orales basadas en lípidos inviolables para agonistas opiáceos
CA2731801C (en) * 2007-07-23 2013-11-26 Kingsway Pharmaceuticals Inc. Therapeutic formulations for the treatment of cold and flu-like symptoms
ES2406939T3 (es) 2007-10-19 2013-06-10 Otsuka Pharmaceutical Co., Ltd. Preparación farmacéutica de matriz sólida
RU2567723C2 (ru) 2009-07-22 2015-11-10 Грюненталь Гмбх Стабильная при окислении, прочная на излом лекарственная форма
WO2011041414A1 (en) * 2009-09-30 2011-04-07 Acura Pharmaceuticals, Inc. Methods and compositions for deterring abuse
CN103857386A (zh) 2011-07-29 2014-06-11 格吕伦塔尔有限公司 提供药物立即释放的抗破碎片剂
JP2014524925A (ja) 2011-07-29 2014-09-25 グリュネンタール・ゲゼルシャフト・ミト・ベシュレンクテル・ハフツング 即時薬剤放出を提供するタンパーレジスタント錠剤
WO2013036567A2 (en) * 2011-09-07 2013-03-14 Johnson Brent A Methods, compositions, and compounds for the reduction of illegal methamphetamine production
WO2013089986A1 (en) * 2011-12-12 2013-06-20 Product And Technology Partners Llc Improved denaturants for sympathomimetic amines
WO2014022541A1 (en) * 2012-08-01 2014-02-06 Acura Pharmaceuticals, Inc. Stabilization of one-pot methamphetamine synthesis systems
JP5922851B2 (ja) 2012-11-30 2016-05-24 アキュラ・ファーマシューティカルズ・インコーポレーテッド 活性医薬成分の自己制御放出
NZ716482A (en) * 2013-07-03 2017-07-28 Acura Pharmaceuticals Inc Methods and compositions for deterring abuse
BR112016000194A8 (pt) 2013-07-12 2019-12-31 Gruenenthal Gmbh forma de dosagem resistente à violação contendo o polímero de acetato de etileno-vinila
BR112016010482B1 (pt) 2013-11-26 2022-11-16 Grünenthal GmbH Preparação de uma composição farmacêutica em pó por meio de criomoagem
CA2943728C (en) 2014-03-26 2020-03-24 Sun Pharma Advanced Research Company Ltd. Abuse deterrent immediate release biphasic matrix solid dosage form
US11103581B2 (en) 2015-08-31 2021-08-31 Acura Pharmaceuticals, Inc. Methods and compositions for self-regulated release of active pharmaceutical ingredient
EP3346991A1 (en) * 2015-09-10 2018-07-18 Grünenthal GmbH Protecting oral overdose with abuse deterrent immediate release formulations
TW202002957A (zh) 2018-02-09 2020-01-16 德商歌林達有限公司 包含轉化抑制劑之麻黃素及其衍生物之抗損壞調配物

Family Cites Families (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3169092A (en) 1963-09-26 1965-02-09 Richardson Merrell Inc Stabilization of amines by tartrazine and bisulfite
US3546142A (en) * 1967-01-19 1970-12-08 Amicon Corp Polyelectrolyte structures
US3773920A (en) * 1971-07-14 1973-11-20 Nikken Chemicals Co Ltd Sustained release medicinal composition
GB1593261A (en) 1976-07-23 1981-07-15 Inveresk Res Int Controlled release suppository
RO68771A2 (ro) * 1976-08-25 1980-08-15 Intreprinderea De Medicamente,Ro Unguent antipruriginos si sicativ
SU1146046A1 (ru) 1983-11-11 1985-03-23 Центральный Ордена Ленина Институт Усовершенствования Врачей Состав дл ретракции десны
US4493827A (en) 1983-11-14 1985-01-15 Ronald Valle Method of inducing sleep
US4601894A (en) * 1985-03-29 1986-07-22 Schering Corporation Controlled release dosage form comprising acetaminophen, pseudoephedrine sulfate and dexbrompheniramine maleate
US4657757A (en) 1985-03-29 1987-04-14 Schering Corporation Controlled release dosage form comprising acetaminophen, pseudoephedrine sulfate and dexbrompheniramine maleate
US4800087A (en) * 1986-11-24 1989-01-24 Mehta Atul M Taste-masked pharmaceutical compositions
US5026560A (en) * 1987-01-29 1991-06-25 Takeda Chemical Industries, Ltd. Spherical granules having core and their production
US4894239A (en) 1987-06-02 1990-01-16 Takeda Chemical Industries, Ltd. Sustained-release preparation and production thereof
ZA904021B (en) 1989-11-24 1991-02-27 Van Der Linde Leon Slimming preparations
CA2068402C (en) 1991-06-14 1998-09-22 Michael R. Hoy Taste mask coatings for preparation of chewable pharmaceutical tablets
US5407686A (en) 1991-11-27 1995-04-18 Sidmak Laboratories, Inc. Sustained release composition for oral administration of active ingredient
US5518730A (en) * 1992-06-03 1996-05-21 Fuisz Technologies Ltd. Biodegradable controlled release flash flow melt-spun delivery system
EP1166801A1 (en) 1993-06-04 2002-01-02 Warner-Lambert Company Preparations containing silicon dioxide to improve the taste thereof
US5543405A (en) 1993-10-22 1996-08-06 Keown; Wendy J. Composition and method for weight reduction and long term management of obesity
AUPM814994A0 (en) 1994-09-14 1994-10-06 Sterling Winthrop Inc. Codeine-containing formulations
US5529783A (en) 1994-12-19 1996-06-25 Mcneil-Ppc, Inc. Rotor granulation and coating of acetaminophen, pseudoephedrine, chlorpheniramine, and, optionally dextromethorphan
US5626878A (en) * 1995-01-10 1997-05-06 Warner Lambert Company Reduction of electrostatic forces between magnesium trisilicate adsorbates
SI0894010T1 (en) 1996-04-10 2003-10-31 Warner-Lambert Company Llc Denaturants for sympathomimetic amine salts
GT199900148A (es) * 1998-09-10 2001-02-28 Desnaturalizantes para las sales aminas simpaticomimeticas.

Also Published As

Publication number Publication date
AR032730A1 (es) 2003-11-26
WO2000015261A1 (en) 2000-03-23
MY117971A (en) 2004-08-30
US20020082304A1 (en) 2002-06-27
PE20001034A1 (es) 2000-10-18
US20060216268A1 (en) 2006-09-28
CR6106A (es) 2003-12-05
AU2004202702B2 (en) 2007-11-22
NZ510012A (en) 2002-11-26
AU771194B2 (en) 2004-03-18
TW550071B (en) 2003-09-01
PA8481601A1 (es) 2001-04-30
CO5280050A1 (es) 2003-05-30
SV1999000148A (es) 2000-09-11
CA2339354A1 (en) 2000-03-23
EP1112089A1 (en) 2001-07-04
CN1316911A (zh) 2001-10-10
UY25702A1 (es) 1999-11-17
US6359011B1 (en) 2002-03-19
BR9913575A (pt) 2001-05-22
JP2002524534A (ja) 2002-08-06
CN1201822C (zh) 2005-05-18
AU2004202702A1 (en) 2004-07-15
HK1039898A1 (zh) 2002-05-17
HN1999000156A (es) 2003-08-01
AU5915799A (en) 2000-04-03
KR20010075021A (ko) 2001-08-09
US20050256194A1 (en) 2005-11-17

Similar Documents

Publication Publication Date Title
GT199900148A (es) Desnaturalizantes para las sales aminas simpaticomimeticas.
UY26968A1 (es) Agentes terapéuticos
AR029216A1 (es) Compuestos inhibidores no peptidicos de la union celular dependiente de vla-4 utiles en el tratamiento de enfermedades inflamatorias, autoinmunes y respiratorias; composicion farmaceutica y procedimiento de tratamiento
ES2196377T3 (es) Derivados de naftiridina.
UY26839A1 (es) Productos de derivados de la 4 - fenil - piridina
PA8507601A1 (es) Nuevos derivados de benzoimidazol utiles como agentes antiproliferativos
HN2001000224A (es) Compuestos de imidazol condensado con arilo o heteroarilo como agentes anti - inflamatorios y analgesicos.
ES2193337T3 (es) Utilizacion de sales de estroncio para el tratamiento de la artrosis.
AR011114A1 (es) COMPOSICIoN FARMACÉUTICA LIBRE DE LACTOSA EN FORMA GRANULADA O EN MEZCLA PARA EL TRATAMIENTO DE DESoRDENES INDUCIDOS POR HISTAMINA.
UY30440A1 (es) Nuevos compuestos
AR008377A1 (es) Un compuesto derivado de la 3-aroilbencilpiridazinona, una composicion farmaceutica particularmente para el tratamiento de enfermedades inflamatorias o autoinmunes que contiene dicho compuesto
PA8452001A1 (es) Derivados de macrolidos c-4" sustituidos
PA8591701A1 (es) Derivados de pirrolopirimidina
AR012671A1 (es) Composiciones farmaceuticas para el tratamiento o profilaxis de la constipacion, los usos de dichas composiciones y los procesos para prepararlos
AR029403A1 (es) Derivados n-sustituidos de carbamoiloxialquil-azolio,un proceso para su fabricacion, composicion farmaceutica y el uso de los mismos para la preparacion de un medicamento
AR024060A1 (es) Nuevos compuestos farmaceuticamente activos
ES2136037B1 (es) Inhibidores de sulfamida-metaloproteasa
HN2004000232A (es) " derivados de pirrolo(3,4-c) pirazol activos como inhibidores de quinasa, proceso para su preparacion y composiciones farmaceuticas que los comprenden."
CO5690566A2 (es) Metodo para inhibir la produccion de lipoproteina remanente
PA8542901A1 (es) Uso de (z)-2-ciano-3-hidroxi-but-2-acido enoico-(4-trifluorometilfenil)-amida para tratar la esclerosis multiple
ES2160680T3 (es) Utilizacion de un antagonista de sustancia p en una composicion farmaceutica.
ES2179523T3 (es) Metodo para aumentar la biodisponibilidad de la fexofenadina y sus derivados.
ES2192263T3 (es) Derivados de benzo(c)quinolizina, su preparacion y empleo como inhibidores de 5-alfa-reductasas.
PA8450901A1 (es) Derivados de eritromicina
SV1997000033A (es) Derivados de acido 4-arilbutirico sustituido como inhibisor de matriz de metaloproteasa