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ES2178094T3 - Hemilsulfato de ester propilico de acido ((s)-1-((s)-2-(trans-4-amino-ciclohexilmetil) carbamoil) -pirrolidin-1-carbonil) -2-isopropiltio-2-metilpropil) carbamico. - Google Patents

Hemilsulfato de ester propilico de acido ((s)-1-((s)-2-(trans-4-amino-ciclohexilmetil) carbamoil) -pirrolidin-1-carbonil) -2-isopropiltio-2-metilpropil) carbamico.

Info

Publication number
ES2178094T3
ES2178094T3 ES98121904T ES98121904T ES2178094T3 ES 2178094 T3 ES2178094 T3 ES 2178094T3 ES 98121904 T ES98121904 T ES 98121904T ES 98121904 T ES98121904 T ES 98121904T ES 2178094 T3 ES2178094 T3 ES 2178094T3
Authority
ES
Spain
Prior art keywords
trans
methylpropil
isopropiltio
hemylsulphate
ciclohexilmetil
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES98121904T
Other languages
English (en)
Inventor
Norimichi Iwase
Naoto Inakoshi
Koichi Sugawara
Jun Anabuki
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Mitsubishi Chemical Corp
Original Assignee
Mitsubishi Chemical Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Mitsubishi Chemical Corp filed Critical Mitsubishi Chemical Corp
Application granted granted Critical
Publication of ES2178094T3 publication Critical patent/ES2178094T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/06—Dipeptides
    • C07K5/06008—Dipeptides with the first amino acid being neutral
    • C07K5/06017—Dipeptides with the first amino acid being neutral and aliphatic
    • C07K5/0606—Dipeptides with the first amino acid being neutral and aliphatic the side chain containing heteroatoms not provided for by C07K5/06086 - C07K5/06139, e.g. Ser, Met, Cys, Thr
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/04—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D207/10—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D207/16—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyrrole Compounds (AREA)

Abstract

LA PRESENTE INVENCION SE REFIERE A UN PROPIL ESTER DE ACIDO ((S) - 1 - ((S) - 2 - ((TRANS - 4 AMINOCICLOHEXILMETIL) CARBAMOIL) PIRROLIDINA - 1 - CARBONIL) - 2 - ISO - PROPILTIO - 2 - METILPROPIL) CARBAMICO SAL SULFATO, REPRESENTADO POR LA FORMULA (I): Y ADEMAS UN HIDRATO O UN SOLVATO DE DICHO COMPUESTO.
ES98121904T 1997-11-19 1998-11-18 Hemilsulfato de ester propilico de acido ((s)-1-((s)-2-(trans-4-amino-ciclohexilmetil) carbamoil) -pirrolidin-1-carbonil) -2-isopropiltio-2-metilpropil) carbamico. Expired - Lifetime ES2178094T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP31809597 1997-11-19

Publications (1)

Publication Number Publication Date
ES2178094T3 true ES2178094T3 (es) 2002-12-16

Family

ID=18095438

Family Applications (1)

Application Number Title Priority Date Filing Date
ES98121904T Expired - Lifetime ES2178094T3 (es) 1997-11-19 1998-11-18 Hemilsulfato de ester propilico de acido ((s)-1-((s)-2-(trans-4-amino-ciclohexilmetil) carbamoil) -pirrolidin-1-carbonil) -2-isopropiltio-2-metilpropil) carbamico.

Country Status (5)

Country Link
US (1) US6117897A (es)
EP (1) EP0918054B1 (es)
AT (1) ATE218124T1 (es)
DE (1) DE69805592T2 (es)
ES (1) ES2178094T3 (es)

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2140598C (en) * 1994-01-27 2010-03-09 Masahiro Ohshima Prolineamide derivatives
KR100445094B1 (ko) * 1995-07-26 2005-06-17 미쓰비시 가가꾸 가부시키가이샤 페니실라민아미드유도체

Also Published As

Publication number Publication date
US6117897A (en) 2000-09-12
EP0918054A1 (en) 1999-05-26
DE69805592T2 (de) 2003-01-09
EP0918054B1 (en) 2002-05-29
DE69805592D1 (de) 2002-07-04
ATE218124T1 (de) 2002-06-15

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