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ATE218124T1 - Ein 1/2-sulfat des ((s)-1-((s)-2-((trans-4- aminocyclohexylmethyl)carbamoyl)-pyrrolidine-1- carbonyl)-2-iso-propylthio-2-methylpropyl)- carbamidsäurepropylesters - Google Patents

Ein 1/2-sulfat des ((s)-1-((s)-2-((trans-4- aminocyclohexylmethyl)carbamoyl)-pyrrolidine-1- carbonyl)-2-iso-propylthio-2-methylpropyl)- carbamidsäurepropylesters

Info

Publication number
ATE218124T1
ATE218124T1 AT98121904T AT98121904T ATE218124T1 AT E218124 T1 ATE218124 T1 AT E218124T1 AT 98121904 T AT98121904 T AT 98121904T AT 98121904 T AT98121904 T AT 98121904T AT E218124 T1 ATE218124 T1 AT E218124T1
Authority
AT
Austria
Prior art keywords
aminocyclohexylmethyl
trans
sulfate
propylesters
propylthio
Prior art date
Application number
AT98121904T
Other languages
English (en)
Inventor
Norimichi Iwase
Naoto Inakoshi
Aoba-Ku
Koichi Sugawara
Jun Anabuki
Original Assignee
Mitsubishi Chem Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Mitsubishi Chem Corp filed Critical Mitsubishi Chem Corp
Application granted granted Critical
Publication of ATE218124T1 publication Critical patent/ATE218124T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/06—Dipeptides
    • C07K5/06008—Dipeptides with the first amino acid being neutral
    • C07K5/06017—Dipeptides with the first amino acid being neutral and aliphatic
    • C07K5/0606—Dipeptides with the first amino acid being neutral and aliphatic the side chain containing heteroatoms not provided for by C07K5/06086 - C07K5/06139, e.g. Ser, Met, Cys, Thr
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/04—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D207/10—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D207/16—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyrrole Compounds (AREA)
AT98121904T 1997-11-19 1998-11-18 Ein 1/2-sulfat des ((s)-1-((s)-2-((trans-4- aminocyclohexylmethyl)carbamoyl)-pyrrolidine-1- carbonyl)-2-iso-propylthio-2-methylpropyl)- carbamidsäurepropylesters ATE218124T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP31809597 1997-11-19

Publications (1)

Publication Number Publication Date
ATE218124T1 true ATE218124T1 (de) 2002-06-15

Family

ID=18095438

Family Applications (1)

Application Number Title Priority Date Filing Date
AT98121904T ATE218124T1 (de) 1997-11-19 1998-11-18 Ein 1/2-sulfat des ((s)-1-((s)-2-((trans-4- aminocyclohexylmethyl)carbamoyl)-pyrrolidine-1- carbonyl)-2-iso-propylthio-2-methylpropyl)- carbamidsäurepropylesters

Country Status (5)

Country Link
US (1) US6117897A (de)
EP (1) EP0918054B1 (de)
AT (1) ATE218124T1 (de)
DE (1) DE69805592T2 (de)
ES (1) ES2178094T3 (de)

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU1025795A (en) * 1994-01-27 1995-08-03 Mitsubishi Chemical Corporation Prolineamide derivatives
CA2227607C (en) * 1995-07-26 2008-06-10 Mitsubishi Chemical Corporation Penicillaminamide derivatives

Also Published As

Publication number Publication date
US6117897A (en) 2000-09-12
ES2178094T3 (es) 2002-12-16
EP0918054A1 (de) 1999-05-26
EP0918054B1 (de) 2002-05-29
DE69805592D1 (de) 2002-07-04
DE69805592T2 (de) 2003-01-09

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Legal Events

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