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ES2173044A1 - Glicina, n-(n-l- -glutamil-3-(nitrosotio)-l-valil) y sus aplicaciones. - Google Patents

Glicina, n-(n-l- -glutamil-3-(nitrosotio)-l-valil) y sus aplicaciones.

Info

Publication number
ES2173044A1
ES2173044A1 ES200100577A ES200100577A ES2173044A1 ES 2173044 A1 ES2173044 A1 ES 2173044A1 ES 200100577 A ES200100577 A ES 200100577A ES 200100577 A ES200100577 A ES 200100577A ES 2173044 A1 ES2173044 A1 ES 2173044A1
Authority
ES
Spain
Prior art keywords
nitrosothio
valyl
glutamyl
glycine
gamma
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
ES200100577A
Other languages
English (en)
Other versions
ES2173044B1 (es
Inventor
Moliner Jose Repolles
Perez-Rasilla Eduardo Salas
Coy Francisco Pubill
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Lacer SA
Original Assignee
Lacer SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lacer SA filed Critical Lacer SA
Priority to ES200100577A priority Critical patent/ES2173044B1/es
Priority to AU2002310939A priority patent/AU2002310939A1/en
Priority to PCT/EP2002/002598 priority patent/WO2002085847A2/en
Priority to PE2002000189A priority patent/PE20021040A1/es
Priority to PA20028541201A priority patent/PA8541201A1/es
Publication of ES2173044A1 publication Critical patent/ES2173044A1/es
Application granted granted Critical
Publication of ES2173044B1 publication Critical patent/ES2173044B1/es
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/02—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link
    • C07K5/0215—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link containing natural amino acids, forming a peptide bond via their side chain functional group, e.g. epsilon-Lys, gamma-Glu
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Hematology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Diabetes (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Peptides Or Proteins (AREA)

Abstract

La presente invención se refiere a glicina, N-[N-L-{ga}-glutamil- 3-(nitrosotio)-L-valil] de la siguiente fórmula (I): **FIGURA1** y a sus sales fisiológicamente aceptables, así como a productos farmacéuticos que contienen uno o varios de estos compuestos, a los métodos de tratamiento y prevención de enfermedades, inclusive la administración de una cantidad eficaz de uno o varios de dichos compuestos y a la utilización de uno o varios de dichos compuestos para la producción de un medicamento para el tratamiento y la prevención de enfermedades.
ES200100577A 2001-03-13 2001-03-13 Derivados de glicina, n-(n-l-gamma-glutamil-3-(nitrosotio)-l-valil) y sus aplicaciones. Expired - Fee Related ES2173044B1 (es)

Priority Applications (5)

Application Number Priority Date Filing Date Title
ES200100577A ES2173044B1 (es) 2001-03-13 2001-03-13 Derivados de glicina, n-(n-l-gamma-glutamil-3-(nitrosotio)-l-valil) y sus aplicaciones.
AU2002310939A AU2002310939A1 (en) 2001-03-13 2002-03-08 Glycine, n-(n-l-gamma-glutamyl-3-(nitrosothio)-l-valyl) and use thereof
PCT/EP2002/002598 WO2002085847A2 (en) 2001-03-13 2002-03-08 Glycine, n-[n-l-gamma-glutamyl-3-(nitrosothio)-l-valyl] and use thereof
PE2002000189A PE20021040A1 (es) 2001-03-13 2002-03-11 GLICINA, N-[N-L-g-GLUTAMIL-3-(NITROSOTIO)-L-VALIL] Y SUS APLICACIONES
PA20028541201A PA8541201A1 (es) 2001-03-13 2002-03-12 Glicina, n-[n-l-gamma-glutamil-3-(nitrosotio)-l-valil] y sus aplicaciones

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
ES200100577A ES2173044B1 (es) 2001-03-13 2001-03-13 Derivados de glicina, n-(n-l-gamma-glutamil-3-(nitrosotio)-l-valil) y sus aplicaciones.

Publications (2)

Publication Number Publication Date
ES2173044A1 true ES2173044A1 (es) 2002-10-01
ES2173044B1 ES2173044B1 (es) 2004-01-16

Family

ID=8497059

Family Applications (1)

Application Number Title Priority Date Filing Date
ES200100577A Expired - Fee Related ES2173044B1 (es) 2001-03-13 2001-03-13 Derivados de glicina, n-(n-l-gamma-glutamil-3-(nitrosotio)-l-valil) y sus aplicaciones.

Country Status (5)

Country Link
AU (1) AU2002310939A1 (es)
ES (1) ES2173044B1 (es)
PA (1) PA8541201A1 (es)
PE (1) PE20021040A1 (es)
WO (1) WO2002085847A2 (es)

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0412699A2 (en) * 1989-08-07 1991-02-13 Takeda Chemical Industries, Ltd. Nitrosothiol derivatives, their production and use
WO2000044714A1 (es) * 1999-01-27 2000-08-03 Lacer, S.A. S-nitrosotioles como agentes para el tratamiento de disfunciones circulatorias

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0412699A2 (en) * 1989-08-07 1991-02-13 Takeda Chemical Industries, Ltd. Nitrosothiol derivatives, their production and use
WO2000044714A1 (es) * 1999-01-27 2000-08-03 Lacer, S.A. S-nitrosotioles como agentes para el tratamiento de disfunciones circulatorias

Also Published As

Publication number Publication date
WO2002085847A2 (en) 2002-10-31
ES2173044B1 (es) 2004-01-16
AU2002310939A1 (en) 2002-11-05
PE20021040A1 (es) 2002-11-19
WO2002085847A3 (en) 2003-10-30
PA8541201A1 (es) 2003-02-28

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