[go: up one dir, main page]
More Web Proxy on the site http://driver.im/

ES2141706T3 - Formulaciones y su empleo en el tratamiento de enfermedades neurologicas. - Google Patents

Formulaciones y su empleo en el tratamiento de enfermedades neurologicas.

Info

Publication number
ES2141706T3
ES2141706T3 ES91310143T ES91310143T ES2141706T3 ES 2141706 T3 ES2141706 T3 ES 2141706T3 ES 91310143 T ES91310143 T ES 91310143T ES 91310143 T ES91310143 T ES 91310143T ES 2141706 T3 ES2141706 T3 ES 2141706T3
Authority
ES
Spain
Prior art keywords
active agent
treatment
formulations
administration
neurological diseases
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES91310143T
Other languages
English (en)
Inventor
Joseph Gerard Masterson
Michael Myers
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Perrigo Co PLC
Original Assignee
Elan Corp PLC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=11039244&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ES2141706(T3) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Elan Corp PLC filed Critical Elan Corp PLC
Application granted granted Critical
Publication of ES2141706T3 publication Critical patent/ES2141706T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4409—Non condensed pyridines; Hydrogenated derivatives thereof only substituted in position 4, e.g. isoniazid, iproniazid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5005—Wall or coating material
    • A61K9/5021—Organic macromolecular compounds
    • A61K9/5026—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5073—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals having two or more different coatings optionally including drug-containing subcoatings
    • A61K9/5078—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals having two or more different coatings optionally including drug-containing subcoatings with drug-free core
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5084—Mixtures of one or more drugs in different galenical forms, at least one of which being granules, microcapsules or (coated) microparticles according to A61K9/16 or A61K9/50, e.g. for obtaining a specific release pattern or for combining different drugs
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A61K9/7015—Drug-containing film-forming compositions, e.g. spray-on
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Epidemiology (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Dermatology (AREA)
  • Hospice & Palliative Care (AREA)
  • Psychiatry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Saccharide Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Pyridine Compounds (AREA)

Abstract

FORMULACIONES FARMACEUTICAS INCLUYENDO UN AGENTE ACTIVO MONO-O DI-AMINOPIRIDINA PARA ADMINISTRAR UNA O DOS VECES DIARIAS PARA UTILIZAR EN EL TRATAMIENTO DE ENFERMEDADES NEURALGICAS, EN PARTICULAR ESCLEROSIS MULTIPLE Y LA ENFERMEDAD DE ALZHEIMER. LAS FORMULACIONES, QUE SON ADECUADAS PARA ADMINISTRACION ORAL O PERCUTANEA DE UN AGENTE ACTIVO, INCLUYEN UN AGENTE ACTIVO EN UN TRANSPORTADOR EFECTIVO PARA PERMITIR LA ELIMINACION DE MONO O DI-AMINOPIRIDINA EN UNA RAZON PERMITIENDO LA ABSORCION CONTROLADA DE LO MISMO, COMO TERMINO MEDIO NO MENOS DE UN PERIODO DE 12 HORAS Y A UNA RAZON SUFICIENTE COMO PARA PERMITIR CONSEGUIR NIVELES EN SANGRE TERAPEUTICAMENTE EFECTIVOS EN UN PERIODO DE 12-24 HORAS DESPUES DE SU ADMINISTRACION.
ES91310143T 1990-11-02 1991-11-01 Formulaciones y su empleo en el tratamiento de enfermedades neurologicas. Expired - Lifetime ES2141706T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IE395290A IE82916B1 (en) 1990-11-02 1990-11-02 Formulations and their use in the treatment of neurological diseases

Publications (1)

Publication Number Publication Date
ES2141706T3 true ES2141706T3 (es) 2000-04-01

Family

ID=11039244

Family Applications (1)

Application Number Title Priority Date Filing Date
ES91310143T Expired - Lifetime ES2141706T3 (es) 1990-11-02 1991-11-01 Formulaciones y su empleo en el tratamiento de enfermedades neurologicas.

Country Status (16)

Country Link
US (3) US5370879A (es)
EP (1) EP0484186B1 (es)
JP (1) JPH04273820A (es)
AT (1) ATE188118T1 (es)
AU (1) AU657706B2 (es)
CA (1) CA2054822C (es)
CS (1) CS331391A3 (es)
DE (2) DE69131880T2 (es)
DK (1) DK0484186T3 (es)
ES (1) ES2141706T3 (es)
GR (1) GR3032769T3 (es)
HU (1) HUT74906A (es)
IE (1) IE82916B1 (es)
LU (1) LU91894I2 (es)
NZ (1) NZ240439A (es)
ZA (1) ZA918711B (es)

Families Citing this family (99)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5221683A (en) * 1984-03-19 1993-06-22 The Rockefeller University Diaminopyridine compounds and methods of use
US5922351A (en) * 1991-03-27 1999-07-13 Bayer Corporation Lubricants for use in tabletting
CA2085785C (en) * 1992-12-18 2005-03-15 Robert R. Hansebout The use of 4-aminopyridine in the treatment of a neurological condition
WO1995000088A1 (en) * 1993-06-23 1995-01-05 Masiz John J Molecular transdermal transport system
US5554381A (en) * 1993-08-09 1996-09-10 Cygnus, Inc. Low flux matrix system for delivering potent drugs transdermally
DE4332394A1 (de) * 1993-09-23 1995-03-30 Falk Pharma Gmbh Budesonid-Pellets mit kontrolliertem Freigabeprofil und Verfahren zu ihrer Herstellung
AT403988B (de) * 1994-05-18 1998-07-27 Lannacher Heilmittel Festes orales retardpräparat
TW304167B (es) * 1995-01-30 1997-05-01 Lilly Co Eli
US6245351B1 (en) 1996-03-07 2001-06-12 Takeda Chemical Industries, Ltd. Controlled-release composition
US6512010B1 (en) * 1996-07-15 2003-01-28 Alza Corporation Formulations for the administration of fluoxetine
DE19835346A1 (de) * 1998-08-05 2000-02-10 Boehringer Ingelheim Pharma Zweiteilige Kapsel zur Aufnahme von pharmazeutischen Zubereitungen für Pulverinhalatoren
US7582680B1 (en) 1998-11-12 2009-09-01 Purdue Research Foundation Methods and compositions for treating mammalian spinal cord injuries
JP2002535353A (ja) * 1999-01-29 2002-10-22 ロザン ファルマ ゲゼルシャフトミットベシュレンクテルハフツンク 医薬品組成物
US6723342B1 (en) 1999-02-08 2004-04-20 Fmc Corporation Edible coating composition
US6432448B1 (en) 1999-02-08 2002-08-13 Fmc Corporation Edible coating composition
DK1152760T3 (da) * 1999-02-09 2007-07-30 Uab Research Foundation Anvendelse af 4-aminopyridin til behandling af perifere neuropatier
US6528086B2 (en) * 1999-09-28 2003-03-04 Zars, Inc. Methods and apparatus for drug delivery involving phase changing formulations
US6500462B1 (en) 1999-10-29 2002-12-31 Fmc Corporation Edible MCC/PGA coating composition
WO2001039753A1 (de) * 1999-11-29 2001-06-07 Lts Lohmann Therapie-Systeme Ag Transdermale therapeutische systeme mit verbesserter stabilität und ein verfahren zu ihrer herstellung
US6419954B1 (en) * 2000-05-19 2002-07-16 Yamanouchi Pharmaceutical Co., Ltd. Tablets and methods for modified release of hydrophilic and other active agents
US6635274B1 (en) 2000-10-27 2003-10-21 Biochemics, Inc. Solution-based transdermal drug delivery system
WO2002043694A2 (en) 2000-11-28 2002-06-06 Fmc Corporation Edible pga(propylene glycol alginate) coating composition
FR2820423B1 (fr) * 2001-02-05 2005-12-02 Assist Publ Hopitaux De Paris Tartrate et phosphate de 3,4-diaminopyridine, compositions pharmaceutiques et utilisations
CA2740056A1 (en) 2001-04-24 2002-11-21 Purdue Research Foundation Methods and compositions for treating mammalian nerve tissue injuries
US20030017133A1 (en) * 2001-06-15 2003-01-23 Wyeth (Formerly American Home Products Corporation) Mucoadhesive composition
US7125563B2 (en) * 2002-04-12 2006-10-24 Dava Pharmaceuticals, Inc. Sustained release pharmaceutical preparations and methods for producing the same
US20040028744A1 (en) * 2002-06-17 2004-02-12 Sauwaluxana Tongaree Mucoadhesive composition
PE20040134A1 (es) * 2002-07-25 2004-03-06 Pharmacia Corp Forma de dosificacion de una vez al dia de pramipexol
AU2003279070A1 (en) * 2002-09-30 2004-04-23 Acusphere Inc Sustained release porous microparticles for inhalation
DK1576138T3 (en) 2002-11-15 2017-05-01 Idenix Pharmaceuticals Llc 2'-METHYL NUCLEOSIDES IN COMBINATION WITH INTERFERON AND FLAVIVIRIDAE MUTATION
US8729107B2 (en) * 2002-12-06 2014-05-20 Purdue Research Foundation Pyridines for treating injured mammalian nerve tissue
JP4903385B2 (ja) * 2002-12-06 2012-03-28 パーデュー・リサーチ・ファウンデーション 損傷した哺乳類神経組織を治療するためのピリジン類
WO2004082684A1 (en) * 2003-03-17 2004-09-30 Acorda Therapeutics Stable oral formulations of aminopyridines and uses thereof
US7384970B2 (en) * 2003-03-24 2008-06-10 Irm Llc Inhibitors of cathepsin S
US20050042289A1 (en) * 2003-04-29 2005-02-24 Yamanouchi Pharma Technologies, Inc. Tablets and methods for modified release of hydrophylic and other active agents
CA2533887A1 (en) * 2003-09-30 2005-04-14 Acusphere, Inc. Injectable, oral, or topical sustained release pharmaceutical formulations
US8007826B2 (en) 2003-12-11 2011-08-30 Acorda Therapeutics, Inc. Sustained release aminopyridine composition
US8354437B2 (en) * 2004-04-09 2013-01-15 Acorda Therapeutics, Inc. Method of using sustained release aminopyridine compositions
US8741332B2 (en) * 2004-06-07 2014-06-03 Nuvo Research Inc. Compositions and methods for dermally treating neuropathic pain
US20070196453A1 (en) * 2004-06-07 2007-08-23 Jie Zhang Two or more non-volatile solvent-containing compositions and methods for dermal delivery of drugs
US8741333B2 (en) 2004-06-07 2014-06-03 Nuvo Research Inc. Compositions and methods for treating dermatitis or psoriasis
US20070196452A1 (en) * 2004-06-07 2007-08-23 Jie Zhang Flux-enabling compositions and methods for dermal delivery of drugs
US20080019927A1 (en) * 2004-06-07 2008-01-24 Jie Zhang Compositions and methods for dermally treating neuropathy with minoxidil
US20070189978A1 (en) * 2004-06-07 2007-08-16 Jie Zhang Compositions and methods for dermally treating musculoskeletal pain
US20070196325A1 (en) * 2004-06-07 2007-08-23 Jie Zhang Compositions and methods for dermally treating infections
US20070196323A1 (en) * 2004-06-07 2007-08-23 Jie Zhang Polyvinyl alcohol-containing compositions and methods for dermal delivery of drugs
US20070196293A1 (en) * 2004-06-07 2007-08-23 Jie Zhang Compositions and methods for treating photo damaged skin
US20070190124A1 (en) * 2004-06-07 2007-08-16 Jie Zhang Two or more solidifying agent-containing compositions and methods for dermal delivery of drugs
US8907153B2 (en) 2004-06-07 2014-12-09 Nuvo Research Inc. Adhesive peel-forming formulations for dermal delivery of drugs and methods of using the same
US20070196457A1 (en) * 2004-06-07 2007-08-23 Jie Zhang Two or more volatile solvent-containing compositions and methods for dermal delivery of drugs
WO2006004774A2 (en) * 2004-06-28 2006-01-12 Stanford University Laulimalide analogues as therapeutic agents
CN101843597A (zh) * 2004-08-13 2010-09-29 贝林格尔·英格海姆国际有限公司 包含普拉克索或其可药用盐的延长释放小球制剂、其制备方法及其用途
EA015335B1 (ru) * 2004-08-13 2011-06-30 Бёрингер Ингельхайм Интернациональ Гмбх Композиция таблетки пролонгированного высвобождения, содержащая прамипексол или его фармацевтически приемлемую соль, способ ее изготовления и ее применение
US7884079B2 (en) * 2004-12-27 2011-02-08 Miller Landon C G 4-aminopyridine and a pharmaceutical composition for treatment of neuronal disorders
EP1807396B1 (en) * 2004-10-29 2013-06-26 Merck Sharp & Dohme Corp. 2-aminopyridine compounds useful as beta-secretase inhibitors for the treatment of alzheimer's disease
US7838522B2 (en) * 2004-11-17 2010-11-23 Ares Trading S.A. Benzothiazole formulations and use thereof
EP1828160B1 (en) * 2004-12-21 2011-12-14 Merck Serono SA Sulfonyl amino cyclic derivatives and use thereof as mmp inhibitors
US8691835B2 (en) * 2004-12-27 2014-04-08 Landon C. G. Miller 4 aminopyridine and a pharmaceutical composition for treatment of neuronal disorders
DE102005001332A1 (de) * 2005-01-11 2006-07-20 Boehringer Ingelheim Pharma Gmbh & Co. Kg Zweiteilige Kapsel mit Vorverschluss zur Aufnahme von pharmazeutischen Zubereitungen für Pulverinhalatoren
RS51957B (en) * 2005-01-31 2012-02-29 Merck Serono Sa. N-HYDROXIAMIDE DERIVATIVES AND THEIR USE
BRPI0613042A2 (pt) * 2005-07-15 2010-12-14 Serono Lab inibidores de jnk para o tratamento de endometriose
CA2609929A1 (en) 2005-07-15 2007-01-25 Agnes Bombrun Glepp-1 inhibitors in the treatment of autoimmune and/or inflammatory disorders
KR20080044836A (ko) 2005-07-15 2008-05-21 라보라뚜와르 세로노 에스. 에이. 자궁내막증 치료용 ｊｎｋ 억제제
US8778395B2 (en) * 2005-08-11 2014-07-15 Andrx Labs, Llc Diltiazem controlled release formulation and method of manufacture
EA013816B1 (ru) * 2005-09-01 2010-08-30 Арес Трейдинг С.А. Лечение неврита зрительного нерва
FR2894143B1 (fr) * 2005-12-01 2008-05-02 Pierre Fabre Medicament Sa Composition a liberation prolongee de l'actif, son procede de preparation et son utilisation.
CA2631492A1 (en) * 2005-12-15 2007-06-21 Acusphere, Inc. Processes for making particle-based pharmaceutical formulations for oral administration
EP1973523A2 (en) * 2005-12-15 2008-10-01 Acusphere, Inc. Processes for making particle-based pharmaceutical formulations for pulmonary or nasal administration
CA2641665A1 (en) * 2006-02-10 2007-08-16 Boehringer Ingelheim International Gmbh Modified release formulation
WO2007090883A1 (en) * 2006-02-10 2007-08-16 Boehringer Ingelheim International Gmbh Extended release formulation
US20070280972A1 (en) * 2006-04-25 2007-12-06 Zars, Inc. Adhesive solid gel-forming formulations for dermal drug delivery
DE102006027791A1 (de) * 2006-06-16 2007-12-20 Lts Lohmann Therapie-Systeme Ag AchE-NMDA-Kombinationswafer
JP2010522249A (ja) * 2006-12-04 2010-07-01 シェブロン ユー．エス．エー． インコーポレイテッド フィッシャー−トロプシュ由来ディーゼル燃料およびその製造方法
US20150111930A1 (en) * 2013-10-23 2015-04-23 Afgin Pharma, Llc Topical regional neuro-affective therapy
US20100034967A1 (en) * 2008-08-07 2010-02-11 Vector Corporation Dry polymer layering using a rotor processor
US20100034968A1 (en) * 2008-08-07 2010-02-11 Vector Corporation Polymer coating process using dry glidant in a rotor processor
US8807070B2 (en) * 2008-08-07 2014-08-19 Vector Corporation Rotor processor for dry powders
US9012477B2 (en) * 2009-01-06 2015-04-21 Nuvo Research Inc. Method of treating neuropathic pain
TW201032809A (en) * 2009-02-11 2010-09-16 Acorda Therapeutics Inc Compositions and methods for extended therapy with aminopyridines
JO3348B1 (ar) * 2009-08-11 2019-03-13 Acorda Therapeutics Inc استخدام 4- بايريدين امينو لتحسين الادراك العصبي و/او التلف النفسي لدى مرضى يعانون من نقص النُخاعين وغير ذلك من امراض الجهاز العصبي
EP2523660A4 (en) 2010-01-14 2013-07-10 Nuvo Res Inc FORMATION OF SOLID FORMS OF LOCAL ANESTHESIA FORMULATIONS FOR FIGHTING PAIN
US10793893B2 (en) 2011-06-30 2020-10-06 Serb Sa Methods of administering 3,4-diaminopyridine
TWI592156B (zh) 2011-10-04 2017-07-21 艾可達醫療公司 使用胺基吡啶以治療與中風有關之感覺動作損傷之方法
CA3131037A1 (en) 2011-11-30 2013-06-06 Emory University Antiviral jak inhibitors useful in treating or preventing retroviral and other viral infections
US20130210866A1 (en) 2012-02-13 2013-08-15 Acorda Therapeutics, Inc. Methods for treating an impairment in gait and/or balance in patients with multiple sclerosis using an aminopyridine
WO2014028387A1 (en) 2012-08-13 2014-02-20 Acorda Therapeutics, Inc. Methods for improving walking capacity in patients with multiple sclerosis using an aminopyridine
WO2014093475A1 (en) 2012-12-11 2014-06-19 Acorda Therapeutics, Inc. Methods for treating parkinson's disease using aminopyridines
EP3427735A1 (en) 2013-04-15 2019-01-16 Acorda Therapeutics, Inc. Methods for treating sensorimotor impairments associated with certain types of stroke using aminopyridines
JP6100150B2 (ja) * 2013-12-06 2017-03-22 久光製薬株式会社 ４−アミノピリジン含有貼付剤
TWI679012B (zh) 2015-09-11 2019-12-11 法德生技藥品股份有限公司 含有達方吡啶的緩釋口服滲透錠劑及其用途
RU2607655C1 (ru) * 2015-09-25 2017-01-10 Общество С Ограниченной Ответственностью "Валента-Интеллект" Способ получения таблеток далфампридина пролонгированного действия
CA2999990A1 (en) 2015-09-29 2017-04-06 Acorda Therapeutics, Inc. Sustained release compositions of 4-aminopyridine
CA3059180C (en) 2017-04-06 2023-10-17 Acorda Therapeutics, Inc. Sustained release compositions of 4-aminopyridine
DE102017115701B4 (de) * 2017-07-12 2022-03-03 Lts Lohmann Therapie-Systeme Ag Fampridin-TTS
WO2019058395A1 (en) * 2017-09-25 2019-03-28 Aizant Drug Research Solutions Private Limited STABLE PHARMACEUTICAL COMPOSITIONS OF DALFAMPRIDINE
US10213393B1 (en) 2018-02-15 2019-02-26 Osmotica Kereskedelmi és Szolgáltató Korlátolt Feleõsségû Társaság Composition and method for treating neurological disease
US10213394B1 (en) 2018-02-15 2019-02-26 Osmotica Kereskedelmi és Szolgáltató Korlátolt Felelõsségû Társaság Composition and method for treating neurological disease
US20190247331A1 (en) 2018-02-15 2019-08-15 Osmotica Kereskedelmi és Szolgáltató Korlátolt Felelõsségû Társaság Composition and method for treating neurological disease
CN114712321B (zh) * 2022-04-22 2024-05-24 河北一品生物医药有限公司 磷酸二氨基吡啶缓释片及其制备方法

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4386095A (en) * 1982-02-22 1983-05-31 Cornell Research Foundation, Inc. Diaminopyridines to improve cognition
IE53703B1 (en) * 1982-12-13 1989-01-18 Elan Corp Plc Drug delivery device
IE54286B1 (en) * 1983-01-18 1989-08-16 Elan Corp Plc Drug delivery device
IE56459B1 (en) * 1983-12-21 1991-08-14 Elan Corp Ltd Controlled absorption pharmaceutical formulation
IE56999B1 (en) * 1983-12-22 1992-03-11 Elan Corp Plc Pharmaceutical formulation
US4894240A (en) * 1983-12-22 1990-01-16 Elan Corporation Plc Controlled absorption diltiazem formulation for once-daily administration
US4562196A (en) * 1984-04-06 1985-12-31 Nelson Research & Development 2,4-Diaminopyridine as a pharmacologic agent
IL86170A (en) * 1987-05-01 1992-12-01 Elan Transdermal Ltd Preparations and compositions comprising nicotine for percutaneous administration
IE64726B1 (en) * 1987-11-20 1995-08-23 Elan Corp Plc Pharmaceutical formulations for preventing drug tolerance

Also Published As

Publication number Publication date
IE82916B1 (en) 2003-06-11
US5370879A (en) 1994-12-06
HUT74906A (en) 1997-03-28
AU8696191A (en) 1992-05-07
DK0484186T3 (da) 2000-04-17
GR3032769T3 (en) 2000-06-30
US5580580A (en) 1996-12-03
US5540938A (en) 1996-07-30
CA2054822A1 (en) 1992-05-03
EP0484186B1 (en) 1999-12-29
ATE188118T1 (de) 2000-01-15
DE69131880T2 (de) 2000-07-20
DE69131880D1 (de) 2000-02-03
HU913447D0 (en) 1992-01-28
LU91894I2 (fr) 2011-12-28
CA2054822C (en) 2004-04-20
NZ240439A (en) 1995-03-28
AU657706B2 (en) 1995-03-23
EP0484186A1 (en) 1992-05-06
JPH04273820A (ja) 1992-09-30
CS331391A3 (en) 1992-05-13
ZA918711B (en) 1992-08-26
DE122011100057I1 (de) 2012-03-15
IE903952A1 (en) 1992-05-22

Similar Documents

Publication Publication Date Title
ES2141706T3 (es) Formulaciones y su empleo en el tratamiento de enfermedades neurologicas.
DE3779500D1 (de) Levodopa-methyl-ester enthaltende pharmazeutische zusammensetzungen, ihre herstellung und therapeutische verwendungen.
ATE328590T1 (de) Pharmazeutische zusammensetzungen enthaltend s-(- )-n-propargyl-1-aminoindan
ATE361093T1 (de) Selektiv auf die leber wirkende pharmazeutisch aktive substanz
AU549481B2 (en) Hair growing agent
ATE241365T1 (de) Saccharid-enthaltende zubereitungen zur behandlung von alzheimerschen erkrankung und von weiteren amyloidosen
KR930702022A (ko) 인슐린의 경구 투여에 의한 타잎 1 당뇨병의 치료 또는 예방법
HUP0100437A2 (hu) Szabályzott felszabadulású gyógyszerkészítmény tolterodin adagolására
PL307339A1 (en) Terephandin metabolites and their optically pure isomers for treating allergic disorders
ATE196081T1 (de) L-dopa ester enthaltende zusammensetzung
DK0412554T3 (da) Sustained-release-præparat til administration i hjernen
CA2143610A1 (en) Use of norastemizole for the treatment of allergic disorders
DK0501705T3 (da) Anvendelse af tomoxetin til behandling af sygdomme i de nedre urinveje
DE60018409D1 (de) Verwendung von antiseptika zur herstelllung von arzneimitteln zur prophylaxe und behandlung von infektionen und/ oder funktionellen gewebeumformungen im körperinneren
DK0629400T3 (da) Idebenon-holdige præparater til behandling af Alzheimer's syge
DE69007065D1 (de) Verwendung von Diadenosin-5',5'''-p1,p4-tetraphosphat zur Herstellung eines Arzneimittels zur Behandlung von Herzkrankheiten.
CA2135752A1 (en) Use of (E)-2-(p-Fluorophenethyl)-3-Fluoroallylamine in the Treatment of Alzheimer's Disease
DK1707568T3 (da) Farmaceutisk sammensætning til anvendelse i behandlingen af ovariecancer hos et menneske, der har sygdommen
IL110888A (en) Pharmaceutical compositions for the treatment of liver diseases comprising a vasodilating compound
GB9109887D0 (en) Pharmaceutical formulations for the treatment of peripheral vascular diseases
RU93004536A (ru) Лекарство для профилактики и терапии неврологических и психиатрических нарушений, возникающих при употреблении алкоголя

Legal Events

Date Code Title Description
FG2A Definitive protection

Ref document number: 484186

Country of ref document: ES