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ES2009147A6 - Nuevo proceso para la preparacion de polimorfos de famotidina - Google Patents

Nuevo proceso para la preparacion de polimorfos de famotidina

Info

Publication number
ES2009147A6
ES2009147A6 ES8702020A ES8702020A ES2009147A6 ES 2009147 A6 ES2009147 A6 ES 2009147A6 ES 8702020 A ES8702020 A ES 8702020A ES 8702020 A ES8702020 A ES 8702020A ES 2009147 A6 ES2009147 A6 ES 2009147A6
Authority
ES
Spain
Prior art keywords
famotidine
prepd
chlorinated hydrocarbon
bio
activity
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES8702020A
Other languages
English (en)
Inventor
Rodes Montserrat Ballester
Nicolau Francisco Eugen Palomo
Coll Antonio Luis Palomo
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Centro Marga Para la Investigacion SA
Original Assignee
Centro Marga Para la Investigacion SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Centro Marga Para la Investigacion SA filed Critical Centro Marga Para la Investigacion SA
Priority to ES8702020A priority Critical patent/ES2009147A6/es
Priority to IL86330A priority patent/IL86330A0/xx
Priority to NO882037A priority patent/NO882037L/no
Priority to IS3342A priority patent/IS3342A7/is
Priority to FI882329A priority patent/FI882329A/fi
Priority to US07/197,329 priority patent/US5021582A/en
Priority to CN88103190A priority patent/CN1030077A/zh
Priority to JP63134279A priority patent/JPH01100162A/ja
Priority to AT88500054T priority patent/ATE69052T1/de
Priority to DE8888500054T priority patent/DE3865899D1/de
Priority to EP88500054A priority patent/EP0297019B1/en
Priority to AU17672/88A priority patent/AU1767288A/en
Priority to KR1019880007442A priority patent/KR920000308B1/ko
Priority to ZA884408A priority patent/ZA884408B/xx
Priority to CA000569954A priority patent/CA1322760C/en
Priority to DK342988A priority patent/DK342988A/da
Publication of ES2009147A6 publication Critical patent/ES2009147A6/es
Expired legal-status Critical Current

Links

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  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

NUEVO PROCESO PARA LA PREPARACION DE POLIMORFOS DE FAMOTIDINA. SE DESCRIBE UN PROCESO PARA LA PREPARACION DE POLIMORFOS DE FAMOTIDINA QUE CONSISTE EN LA ADICION DE UNA BASE ORGANICA O AMIDINA BICICLICA A UNA SOLUCION DE HIDROCLORURO DE FAMOTIDINA. LA SOLUCION RESULTANTE A 50-65GC SE DILUYE CON UN HIDROCARBURO CLORADO DE DONDE PRECIPITA EL POLIMORFO CON DENSIDADES APARENTES RELATIVAS ALTA O BAJA. SE DIFERENCIA DEL POLIMORFO DE ALTO PUNTO DE FUSION Y ALTA DENSIDAD EN SUS PROPIEDADES FISICO-QUIMICAS Y BIOLOGICAS. SON COMPUESTOS DE INTERES EN FORMULACIONES GALENICAS Y PREPARACION DEL MEDICAMENTO PARA SU USO COMO SUSTANCIA ACTIVA PARA COMBATIR LAS AFECCIONES DEL APARATO DIGESTIVO, ULCERA GASTRICA Y DUODENAL, Y TAMBIEN EL SINDROME DE ZOLLINGER-ELLISON.
ES8702020A 1987-06-22 1987-06-22 Nuevo proceso para la preparacion de polimorfos de famotidina Expired ES2009147A6 (es)

Priority Applications (16)

Application Number Priority Date Filing Date Title
ES8702020A ES2009147A6 (es) 1987-06-22 1987-06-22 Nuevo proceso para la preparacion de polimorfos de famotidina
IL86330A IL86330A0 (en) 1987-06-22 1988-05-10 Famotidine polymorphic forms and their preparation
NO882037A NO882037L (no) 1987-06-22 1988-05-10 Famotidin, polymerte former og fremstilling derav.
IS3342A IS3342A7 (is) 1987-06-22 1988-05-11 Famotidine (N-sulfamoyl-3-)2-guanidionthiazol-4-yl) methylthioprooionamidine:) og aðferð til framleiðslu þess.
FI882329A FI882329A (fi) 1987-06-22 1988-05-18 Polymorfiska former av famotidin och foerfarande foer framstaellning daerav.
US07/197,329 US5021582A (en) 1987-06-22 1988-05-23 Famotidine polymorphic forms and their preparation process
CN88103190A CN1030077A (zh) 1987-06-22 1988-05-25 法莫丁啶多晶型物及其制备方法
JP63134279A JPH01100162A (ja) 1987-06-22 1988-05-31 ファモチジン多形型およびそれらの製造方法
AT88500054T ATE69052T1 (de) 1987-06-22 1988-06-01 Polymorphe form des famotidins und ihr herstellungsverfahren.
DE8888500054T DE3865899D1 (de) 1987-06-22 1988-06-01 Polymorphe form des famotidins und ihr herstellungsverfahren.
EP88500054A EP0297019B1 (en) 1987-06-22 1988-06-01 Famotidine polymorphic form and preparation thereof
AU17672/88A AU1767288A (en) 1987-06-22 1988-06-14 Famotidine polymorphic forms and their preparation process
KR1019880007442A KR920000308B1 (ko) 1987-06-22 1988-06-20 안정한 파모티딘결정형 폴리모르프 및 그 제조방법
ZA884408A ZA884408B (en) 1987-06-22 1988-06-21 Famotidine polymorphic forms and their preparation process
CA000569954A CA1322760C (en) 1987-06-22 1988-06-21 Famotidine polymorphic forms and their preparation process
DK342988A DK342988A (da) 1987-06-22 1988-06-22 Polymorfe famotidinformer og fremgangsmaader til fremstilling heraf

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
ES8702020A ES2009147A6 (es) 1987-06-22 1987-06-22 Nuevo proceso para la preparacion de polimorfos de famotidina

Publications (1)

Publication Number Publication Date
ES2009147A6 true ES2009147A6 (es) 1989-09-01

Family

ID=8251688

Family Applications (1)

Application Number Title Priority Date Filing Date
ES8702020A Expired ES2009147A6 (es) 1987-06-22 1987-06-22 Nuevo proceso para la preparacion de polimorfos de famotidina

Country Status (3)

Country Link
ES (1) ES2009147A6 (es)
IS (1) IS3342A7 (es)
ZA (1) ZA884408B (es)

Also Published As

Publication number Publication date
ZA884408B (en) 1989-03-29
IS3342A7 (is) 1988-12-23

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Legal Events

Date Code Title Description
FD1A Patent lapsed

Effective date: 19991209