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ES2094160T3 - Peptidos terapeuticos, en particular analogos del peptido substancia p. - Google Patents

Peptidos terapeuticos, en particular analogos del peptido substancia p.

Info

Publication number
ES2094160T3
ES2094160T3 ES90912128T ES90912128T ES2094160T3 ES 2094160 T3 ES2094160 T3 ES 2094160T3 ES 90912128 T ES90912128 T ES 90912128T ES 90912128 T ES90912128 T ES 90912128T ES 2094160 T3 ES2094160 T3 ES 2094160T3
Authority
ES
Spain
Prior art keywords
amino acid
peptide
acid residue
therapeutic peptides
active site
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES90912128T
Other languages
English (en)
Inventor
David H Coy
Jacques-Pierre Moreau
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Tulane University
Original Assignee
Tulane University
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Tulane University filed Critical Tulane University
Application granted granted Critical
Publication of ES2094160T3 publication Critical patent/ES2094160T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/02—Linear peptides containing at least one abnormal peptide link
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04—Linear peptides containing only normal peptide links
    • C07K7/22—Tachykinins, e.g. Eledoisins, Substance P; Related peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)

Abstract

UN PEPTIDO LINEAL ANALOGO AL QUE NATURALMENTE OCURRE, SUSTANCIA P BIOLOGICAMENTE ACTIVA TENIENDO UN SITIO ACTIVO Y UN SITIO DE FIJACION RESPONSABLE DE LA FIJACION DE DICHO PEPTIDO A UN RECEPTOR EN LA CELULA BLANCO. EL ANALOGO TIENE UN ENLACE NO PEPTIDICO, EN LUGAR DE UN ENLACE PEPTIDICO, ENTRE UN RESIDUO AMINOACIDO DEL SITIO ACTIVO MENCIONADO Y UN RESIDUO AMINOACIDO ADYACENTE, O UN RESIDUO SINTETICO, UN BETA AMINOACIDO , O UN GAMMA AMINOACIDO EN LUGAR DE LOS DOS RESIDUOS AMINOACIDOS DEL SITIO ACTIVO.
ES90912128T 1989-08-16 1990-08-16 Peptidos terapeuticos, en particular analogos del peptido substancia p. Expired - Lifetime ES2094160T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US39472789A 1989-08-16 1989-08-16

Publications (1)

Publication Number Publication Date
ES2094160T3 true ES2094160T3 (es) 1997-01-16

Family

ID=23560172

Family Applications (1)

Application Number Title Priority Date Filing Date
ES90912128T Expired - Lifetime ES2094160T3 (es) 1989-08-16 1990-08-16 Peptidos terapeuticos, en particular analogos del peptido substancia p.

Country Status (15)

Country Link
EP (1) EP0438566B1 (es)
JP (1) JPH04502922A (es)
AT (1) ATE143372T1 (es)
CA (1) CA2039175A1 (es)
CZ (2) CZ285562B6 (es)
DD (1) DD298411A5 (es)
DE (1) DE69028692T2 (es)
DK (1) DK0438566T3 (es)
ES (1) ES2094160T3 (es)
GR (1) GR900100613A (es)
HU (1) HUT65465A (es)
IE (1) IE77033B1 (es)
PT (1) PT95016B (es)
SK (1) SK402890A3 (es)
WO (1) WO1991002745A1 (es)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5410019A (en) * 1987-09-24 1995-04-25 The Administrators Of The Tulane-Educational Fund Therapeutic peptides
FR2680174A1 (fr) * 1991-08-05 1993-02-12 Michelot Robert Nouveaux composes peptidiques, inhibiteurs de l'adsorption du virus hiv sur ses cellules cibles.
EP0533280B2 (en) 1991-09-20 2004-12-01 Glaxo Group Limited Novel medical use for tachykinin antagonists
US6156725A (en) * 1996-08-16 2000-12-05 National Institute Of Immunology Drug for the treatment of cancer
US6492330B1 (en) 1996-08-16 2002-12-10 National Institute Of Immunology Antiangiogenic drugs
EP0835662B1 (en) * 1996-10-08 2001-11-14 National Institute of Immunology A drug for the treatment of cancer
CA2225185A1 (en) 1997-08-11 1999-02-11 Peter K. Law Myoblast transfer therapy for relieving pain and for treating behavioral and perceptive abnormalities
US6316414B1 (en) 2000-07-31 2001-11-13 Dabur Research Foundation Somatostatin analogs for the treatment of cancer
WO2008090117A1 (en) 2007-01-24 2008-07-31 Glaxo Group Limited Pharmaceutical compositions comprising 3, 5-diamin0-6- (2, 3-dichl0phenyl) -l, 2, 4-triazine or r (-) -2, 4-diamino-5- (2, 3-dichlorophenyl) -6-fluoromethyl pyrimidine and an nk1
US20120225817A1 (en) * 2009-11-11 2012-09-06 Santen Pharmaceutical Co., Ltd. Therapeutic agent for gastrointestinal disease
US9446029B2 (en) 2010-07-27 2016-09-20 Colorado State University Research Foundation Use of NK-1 receptor antagonists in management of visceral pain
AR128311A1 (es) * 2022-01-21 2024-04-17 Inst Pasteur De Montevideo Inmunización activa para reducir el dolor osteoarticular, neuropático y en cáncer

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3862114A (en) * 1971-11-22 1975-01-21 Ici Australia Ltd Analogs of substance p
IT1212508B (it) * 1981-12-22 1989-11-22 Anic Spa Analoghi retro - invertiti dei penta - ed esapeptidi c - terminali della sostanza p. utili come vasodilatatori
US4481139A (en) * 1983-04-13 1984-11-06 Board Of Regents, The University Of Texas System Peptide antagonists of substance P
US4803261A (en) * 1986-06-27 1989-02-07 The Administrators Of The Tulane Educational Fund Method for synthesizing a peptide containing a non-peptide
NZ229552A (en) * 1988-06-20 1992-06-25 Merrell Dow Pharma Neurokinin a antagonists

Also Published As

Publication number Publication date
GR900100613A (el) 1991-12-30
DE69028692D1 (de) 1996-10-31
EP0438566A1 (en) 1991-07-31
IE77033B1 (en) 1997-11-19
EP0438566B1 (en) 1996-09-25
SK280796B6 (sk) 2000-07-11
CZ285562B6 (cs) 1999-09-15
HUT65465A (en) 1994-06-28
PT95016B (pt) 1997-05-28
PT95016A (pt) 1991-04-18
ATE143372T1 (de) 1996-10-15
SK402890A3 (en) 2000-07-11
CZ402890A3 (cs) 1999-04-14
WO1991002745A1 (en) 1991-03-07
JPH04502922A (ja) 1992-05-28
CZ285319B6 (cs) 1999-07-14
IE902958A1 (en) 1991-02-27
DE69028692T2 (de) 1997-02-20
EP0438566A4 (en) 1993-03-31
HU906872D0 (en) 1991-07-29
DD298411A5 (de) 1992-02-20
DK0438566T3 (da) 1996-11-11
CA2039175A1 (en) 1991-02-17

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