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ES2074594T3 - Derivados de 4-(4-alcoxifenil)-2-butilamina y su procedimiento de preparacion. - Google Patents

Derivados de 4-(4-alcoxifenil)-2-butilamina y su procedimiento de preparacion.

Info

Publication number
ES2074594T3
ES2074594T3 ES91102630T ES91102630T ES2074594T3 ES 2074594 T3 ES2074594 T3 ES 2074594T3 ES 91102630 T ES91102630 T ES 91102630T ES 91102630 T ES91102630 T ES 91102630T ES 2074594 T3 ES2074594 T3 ES 2074594T3
Authority
ES
Spain
Prior art keywords
derivatives
butilamina
alcoxifenil
preparation procedure
optically active
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES91102630T
Other languages
English (en)
Inventor
Sanji Hagishita
Kaoru Seno
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Shionogi and Co Ltd
Original Assignee
Shionogi and Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Shionogi and Co Ltd filed Critical Shionogi and Co Ltd
Application granted granted Critical
Publication of ES2074594T3 publication Critical patent/ES2074594T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C215/00—Compounds containing amino and hydroxy groups bound to the same carbon skeleton
    • C07C215/46—Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups bound to carbon atoms of at least one six-membered aromatic ring and amino groups bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C217/00—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton
    • C07C217/54—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups bound to carbon atoms of at least one six-membered aromatic ring and amino groups bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton
    • C07C217/56—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups bound to carbon atoms of at least one six-membered aromatic ring and amino groups bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton with amino groups linked to the six-membered aromatic ring, or to the condensed ring system containing that ring, by carbon chains not further substituted by singly-bound oxygen atoms
    • C07C217/62—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups bound to carbon atoms of at least one six-membered aromatic ring and amino groups bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton with amino groups linked to the six-membered aromatic ring, or to the condensed ring system containing that ring, by carbon chains not further substituted by singly-bound oxygen atoms linked by carbon chains having at least three carbon atoms between the amino groups and the six-membered aromatic ring or the condensed ring system containing that ring

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)

Abstract

ESTA INVENCION SE REFIERE A UNA AMINA (+)-SECUNDARIA OPTICAMENTE ACTIVA QUE TIENE LA FORMULA: EN DONDE R ELEVADO 1 ES UN ALQUILO INFERIOR, Y UN PROCESO PARA PREPARAR UN INTERMEDIO UTIL PARA LA PRODUCCION DE LOS DERIVADOS DE DOPAMINA OPTICAMENTE ACTIVA, ES DECIR, AMINA (+)-PRIMARIA OPTICAMENTE ACTIVA QUE TIENE LA FORMULA: EN DONDE R ELEVADO 1 ES UN ALQUILO INFERIOR, QUE SE CARACTERIZA POR LA REDUCCION DE DICHA AMINA (+)-SECUNDARIA OPTICAMENTE ACTIVA.
ES91102630T 1990-02-23 1991-02-22 Derivados de 4-(4-alcoxifenil)-2-butilamina y su procedimiento de preparacion. Expired - Lifetime ES2074594T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP2043547A JP2818958B2 (ja) 1990-02-23 1990-02-23 ４―（４―アルコキシフェニル）―２―ブチルアミン誘導体およびその製造法

Publications (1)

Publication Number Publication Date
ES2074594T3 true ES2074594T3 (es) 1995-09-16

Family

ID=12666781

Family Applications (1)

Application Number Title Priority Date Filing Date
ES91102630T Expired - Lifetime ES2074594T3 (es) 1990-02-23 1991-02-22 Derivados de 4-(4-alcoxifenil)-2-butilamina y su procedimiento de preparacion.

Country Status (8)

Country Link
US (1) US5073648A (es)
EP (1) EP0443606B1 (es)
JP (1) JP2818958B2 (es)
KR (1) KR910021366A (es)
AT (1) ATE122334T1 (es)
DE (1) DE69109514T2 (es)
DK (1) DK0443606T3 (es)
ES (1) ES2074594T3 (es)

Families Citing this family (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6313146B1 (en) 1991-08-23 2001-11-06 Nps Pharmaceuticals, Inc. Calcium receptor-active molecules
US5763569A (en) * 1991-08-23 1998-06-09 The Brigham And Women's Hospital, Inc Calcium receptor-active molecules
US6001884A (en) * 1991-08-23 1999-12-14 Nps Pharmaceuticals, Inc. Calcium receptor-active molecules
US6031003A (en) * 1991-08-23 2000-02-29 Nps Pharmaceuticals, Inc. Calcium receptor-active molecules
US6011068A (en) * 1991-08-23 2000-01-04 Nps Pharmaceuticals, Inc. Calcium receptor-active molecules
US5688938A (en) * 1991-08-23 1997-11-18 The Brigham & Women's Hospital, Inc. Calcium receptor-active molecules
US5858684A (en) * 1991-08-23 1999-01-12 The Brigham And Women's Hospital, Inc. Method of screening calcium receptor-active molecules
US5962314A (en) * 1993-02-23 1999-10-05 Nps Pharmaceuticals, Inc. Calcium receptor-active molecules
EP1553078A1 (en) 1994-10-21 2005-07-13 Nps Pharmaceuticals, Inc. Calcium receptor-active compounds
ATE243186T1 (de) * 1996-05-01 2003-07-15 Nps Pharma Inc Verbindungen , die auf anorganische ionen- rezeptoren wirken
DE19641693A1 (de) 1996-10-10 1998-04-16 Bayer Ag Substituierte 2-Amino-4-alkylamino-1,3,5-triazine
US6252114B1 (en) * 2000-03-24 2001-06-26 Council Of Scientific And Industrial Research Process for preparing novel biologically active synthetic molecule 4-(p-methoxyphenyl)-2-amino-butane
DE60008697T2 (de) * 2000-03-28 2005-02-10 Council Of Scientific And Industrial Research Verfahren zur Herstellung von 4-(P-methoxyphenyl)-2-amino-butane und Insektizide
US6441205B1 (en) * 2000-05-19 2002-08-27 Council Of Scientific And Industrial Research Synthetic precursors to 4-(P-methoxyphenyl)-2-amino-butane
CN101903329B (zh) * 2007-12-21 2014-11-05 巴斯夫欧洲公司 非对映选择性转化手性亚胺的方法
EP2234959B1 (de) * 2007-12-21 2014-10-08 Basf Se Einstufige reduktive aminierung
AU2010234518A1 (en) * 2009-04-09 2012-02-02 Cognition Therapeutics, Inc. Inhibitors of cognitive decline
WO2011014880A1 (en) 2009-07-31 2011-02-03 Cognition Therapeutics, Inc. Inhibitors of cognitive decline
BR112014004414A2 (pt) * 2011-08-25 2017-03-28 Cognition Therapeutics Inc composições e métodos para tratar doença neurodegenerativa
ES2721001T3 (es) 2014-01-31 2019-07-26 Cognition Therapeutics Inc Derivado de isoindolina, y composiciones y métodos para tratar una enfermedad neurodegenerativa
KR102614814B1 (ko) 2017-05-15 2023-12-20 카그니션 테라퓨틱스, 인코퍼레이티드 신경변성 질환 치료용 조성물
CN109851511B (zh) * 2017-11-30 2022-12-06 浙江普利药业有限公司 一种盐酸多巴酚丁胺的合成方法

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2276618A (en) * 1942-03-17 N-phenylaliphatic bihxdroxithenyl-
DE893341C (de) * 1950-08-23 1953-10-15 Troponwerke Dinklage & Co Verfahren zur Herstellung von N-Aralkyl-ª‰-phenyl-isopropylaminen
CH480791A (de) * 1967-01-17 1969-11-15 Ciba Geigy Schädlingsbekämpfungsmittel
US3987200A (en) * 1972-04-12 1976-10-19 Eli Lilly And Company Method for increasing cardiac contractility
US4105695A (en) * 1975-12-11 1978-08-08 Bristol-Myers Company 2-Amino-1-(2,5-dimethoxyphenyl)-butanes
ATE1994T1 (de) * 1979-06-16 1982-12-15 Beecham Group Plc Aethanamin-derivate, ihre herstellung und verwendung in pharmazeutischen zusammensetzungen.
DD153366A1 (de) * 1980-10-03 1982-01-06 Heinrich Foken Verfahren zur herstellung von hydroxyphenylalkylaminen
US4658060A (en) * 1982-04-26 1987-04-14 Schering Corporation Preparation of (-)-5-(beta)-1-hydroxy-2-((beta)-1-methyl-3-phenylpropyl)aminoethyl) salicylamide
US4704407A (en) * 1984-12-20 1987-11-03 Eli Lilly And Company Soluble dobutamine salts
US4663351A (en) * 1985-08-23 1987-05-05 Berlex Laboratories, Inc. Dobutamine tri-isobutyric acid ester and the use thereof as a cardiotonic agent
US5011996A (en) * 1988-07-20 1991-04-30 Bayer Aktiengesellschaft Process for the preparation of amines
JPH0816084B2 (ja) * 1989-05-22 1996-02-21 東レ株式会社 光学活性フェニルエチルアミン誘導体の製造法
JPH0917279A (ja) * 1995-06-28 1997-01-17 Matsushita Electric Works Ltd スイッチ

Also Published As

Publication number Publication date
DK0443606T3 (da) 1995-07-10
EP0443606B1 (en) 1995-05-10
JPH03246258A (ja) 1991-11-01
ATE122334T1 (de) 1995-05-15
KR910021366A (ko) 1991-12-20
US5073648A (en) 1991-12-17
DE69109514D1 (de) 1995-06-14
EP0443606A3 (en) 1992-03-25
JP2818958B2 (ja) 1998-10-30
EP0443606A2 (en) 1991-08-28
DE69109514T2 (de) 1995-12-21

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