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ES2060095T3 - Nuevas imidazobenzodiazepinas y sus sales, procedimiento de preparacion, aplicacion como medicamentos y composiciones que los contienen. - Google Patents

Nuevas imidazobenzodiazepinas y sus sales, procedimiento de preparacion, aplicacion como medicamentos y composiciones que los contienen.

Info

Publication number
ES2060095T3
ES2060095T3 ES90401151T ES90401151T ES2060095T3 ES 2060095 T3 ES2060095 T3 ES 2060095T3 ES 90401151 T ES90401151 T ES 90401151T ES 90401151 T ES90401151 T ES 90401151T ES 2060095 T3 ES2060095 T3 ES 2060095T3
Authority
ES
Spain
Prior art keywords
alkyl
carbon atoms
group
salts
imidazobenzodiazepines
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES90401151T
Other languages
English (en)
Inventor
Charles John Robert Hedgecock
Elizabert Anne Kuo
Stuart Donald Jones
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sanofi Aventis France
Original Assignee
Roussel Uclaf SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Roussel Uclaf SA filed Critical Roussel Uclaf SA
Application granted granted Critical
Publication of ES2060095T3 publication Critical patent/ES2060095T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/04—Anorexiants; Antiobesity agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Neurosurgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Neurology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Biomedical Technology (AREA)
  • Public Health (AREA)
  • Psychiatry (AREA)
  • Child & Adolescent Psychology (AREA)
  • Obesity (AREA)
  • Hospice & Palliative Care (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

LA INVENCION SE REFIERE A NUEVAS IMIDAZOBENZODIACEPINAS DE FORMULA (I), EN LA QUE LOS SUSTITUYENTES R1 REPRESENTAN UN ALCOHILO C1-C3 O FORMAN JUNTOS UN PUENTE ALQUILENO C2-C5; X E Y REPRESENTAN O O S; R2 ES HIDROGENO, ALCOHILO C1-C3; R3 ES HIDROGENO, ALCOHILO C1-C5, FENILO O FENILO SUSTITUIDO; W ES O O S; R4 Y R5 REPRESENTAN HIDROGENO, HALOGENO, HIDROXI, ALCOHILO O ALCOXI C1-C3 O CF3, ENTENDIENDO QUE CUANDO CADA R1 REPRESENTA UN ALCOHILO, X E Y SON IGUALES, ASI COMO SALES DE ADICION CON ACIDOS MINERALES U ORGANICOS, SU OBTENCION, SU APLICACION COMO MEDICAMENTOS, ESPECIALMENTE EN EL TRATAMIENTO DE PROBLEMAS DE LA MEMORIA, EN GERIATRIA Y COMO TRANQUILIZANTES.
ES90401151T 1989-04-27 1990-04-27 Nuevas imidazobenzodiazepinas y sus sales, procedimiento de preparacion, aplicacion como medicamentos y composiciones que los contienen. Expired - Lifetime ES2060095T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB898909700A GB8909700D0 (en) 1989-04-27 1989-04-27 Chemical compounds

Publications (1)

Publication Number Publication Date
ES2060095T3 true ES2060095T3 (es) 1994-11-16

Family

ID=10655860

Family Applications (1)

Application Number Title Priority Date Filing Date
ES90401151T Expired - Lifetime ES2060095T3 (es) 1989-04-27 1990-04-27 Nuevas imidazobenzodiazepinas y sus sales, procedimiento de preparacion, aplicacion como medicamentos y composiciones que los contienen.

Country Status (9)

Country Link
US (1) US5017574A (es)
EP (1) EP0395527B1 (es)
JP (1) JPH0363279A (es)
AT (1) ATE111465T1 (es)
CA (1) CA2015569A1 (es)
DE (1) DE69012407T2 (es)
DK (1) DK0395527T3 (es)
ES (1) ES2060095T3 (es)
GB (1) GB8909700D0 (es)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2015336A1 (en) * 1989-05-19 1990-11-19 F. Hoffmann-La Roche Ag Imidazodiazepines for the treatment of neurological symptoms
GB8927928D0 (en) * 1989-12-11 1990-02-14 Roussel Lab Ltd Chemical compounds
GB9022758D0 (en) * 1990-10-19 1990-12-05 Roussel Lab Ltd Hetero-imidazodiazepine derivatives

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA1143728A (en) * 1979-10-04 1983-03-29 Max Gerecke Imidazodiazepine derivatives
FI880814A (fi) * 1987-03-10 1988-09-11 Hoffmann La Roche Imidazodiazepin-derivat.
GB8720414D0 (en) * 1987-08-28 1987-10-07 Roussel Lab Ltd Chemical compounds

Also Published As

Publication number Publication date
JPH0363279A (ja) 1991-03-19
EP0395527B1 (fr) 1994-09-14
DE69012407D1 (de) 1994-10-20
DE69012407T2 (de) 1995-02-09
DK0395527T3 (da) 1995-02-20
ATE111465T1 (de) 1994-09-15
EP0395527A1 (fr) 1990-10-31
GB8909700D0 (en) 1989-06-14
CA2015569A1 (en) 1990-10-27
US5017574A (en) 1991-05-21

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