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EP2976044A4 - COMPOSITIONS AND METHODS FOR PROMOTING REGENERATION OF DENTAL TISSUE - Google Patents

COMPOSITIONS AND METHODS FOR PROMOTING REGENERATION OF DENTAL TISSUE

Info

Publication number
EP2976044A4
EP2976044A4 EP14771102.2A EP14771102A EP2976044A4 EP 2976044 A4 EP2976044 A4 EP 2976044A4 EP 14771102 A EP14771102 A EP 14771102A EP 2976044 A4 EP2976044 A4 EP 2976044A4
Authority
EP
European Patent Office
Prior art keywords
compositions
methods
tissue regeneration
dental tissue
dental
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP14771102.2A
Other languages
German (de)
English (en)
French (fr)
Other versions
EP2976044A1 (en
Inventor
Jeremy J Mao
Ying Zheng
Guoming Sun
Songlin Wang
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Columbia University in the City of New York
Original Assignee
Columbia University in the City of New York
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Columbia University in the City of New York filed Critical Columbia University in the City of New York
Publication of EP2976044A1 publication Critical patent/EP2976044A1/en
Publication of EP2976044A4 publication Critical patent/EP2976044A4/en
Withdrawn legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/14—Macromolecular materials
    • A61L27/22—Polypeptides or derivatives thereof, e.g. degradation products
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/14—Macromolecular materials
    • A61L27/22—Polypeptides or derivatives thereof, e.g. degradation products
    • A61L27/222—Gelatin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/14—Macromolecular materials
    • A61L27/22—Polypeptides or derivatives thereof, e.g. degradation products
    • A61L27/24—Collagen
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/50—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • A61L27/54—Biologically active materials, e.g. therapeutic substances
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/50—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • A61L27/56—Porous materials, e.g. foams or sponges
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/50—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • A61L27/58—Materials at least partially resorbable by the body
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08L—COMPOSITIONS OF MACROMOLECULAR COMPOUNDS
    • C08L5/00—Compositions of polysaccharides or of their derivatives not provided for in groups C08L1/00 or C08L3/00
    • C08L5/04—Alginic acid; Derivatives thereof
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08L—COMPOSITIONS OF MACROMOLECULAR COMPOUNDS
    • C08L5/00—Compositions of polysaccharides or of their derivatives not provided for in groups C08L1/00 or C08L3/00
    • C08L5/08—Chitin; Chondroitin sulfate; Hyaluronic acid; Derivatives thereof
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08L—COMPOSITIONS OF MACROMOLECULAR COMPOUNDS
    • C08L89/00—Compositions of proteins; Compositions of derivatives thereof
    • C08L89/04—Products derived from waste materials, e.g. horn, hoof or hair
    • C08L89/06—Products derived from waste materials, e.g. horn, hoof or hair derived from leather or skin, e.g. gelatin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/20—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices containing or releasing organic materials
    • A61L2300/252—Polypeptides, proteins, e.g. glycoproteins, lipoproteins, cytokines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/40—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a specific therapeutic activity or mode of action
    • A61L2300/412—Tissue-regenerating or healing or proliferative agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/40—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a specific therapeutic activity or mode of action
    • A61L2300/412—Tissue-regenerating or healing or proliferative agents
    • A61L2300/414—Growth factors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2430/00—Materials or treatment for tissue regeneration
    • A61L2430/12—Materials or treatment for tissue regeneration for dental implants or prostheses

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Dermatology (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Transplantation (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Veterinary Medicine (AREA)
  • Organic Chemistry (AREA)
  • Polymers & Plastics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Dispersion Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Materials For Medical Uses (AREA)
  • Medicinal Preparation (AREA)
EP14771102.2A 2013-03-21 2014-03-21 COMPOSITIONS AND METHODS FOR PROMOTING REGENERATION OF DENTAL TISSUE Withdrawn EP2976044A4 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201361804138P 2013-03-21 2013-03-21
US201361831595P 2013-06-05 2013-06-05
PCT/US2014/031512 WO2014153548A1 (en) 2013-03-21 2014-03-21 Compositions and methods for dental tissue regeneration

Publications (2)

Publication Number Publication Date
EP2976044A1 EP2976044A1 (en) 2016-01-27
EP2976044A4 true EP2976044A4 (en) 2016-11-23

Family

ID=51581532

Family Applications (1)

Application Number Title Priority Date Filing Date
EP14771102.2A Withdrawn EP2976044A4 (en) 2013-03-21 2014-03-21 COMPOSITIONS AND METHODS FOR PROMOTING REGENERATION OF DENTAL TISSUE

Country Status (3)

Country Link
EP (1) EP2976044A4 (zh)
CN (1) CN105228557A (zh)
WO (1) WO2014153548A1 (zh)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9937126B2 (en) * 2013-10-02 2018-04-10 The Board Of Trustees Of The Leland Stanford Junior University Wnt compositions and methods for purification
CA3009983A1 (en) 2014-12-29 2016-07-07 The Board Of Trustees Of The Leland Stanford Junior University Lyposomal wnt3a for use in treating tooth sensitivity
CN104548212B (zh) * 2014-12-31 2018-05-11 新科沃再生医学（苏州）有限公司 一种促进牙髓及牙本质再生的组合物
KR101772449B1 (ko) * 2016-12-27 2017-08-30 주식회사 하이센스바이오 신규한 펩타이드
CN107115561B (zh) * 2017-06-19 2019-11-26 中山大学附属口腔医院 一种3d打印支架材料及其制备方法和应用
CN109846885A (zh) * 2019-04-04 2019-06-07 南通大学附属医院 瑞舒伐他汀的新用途
RU2700933C1 (ru) * 2019-05-27 2019-09-24 Артем Иванович Трофименко Гидрогель для регенерации пульпы зуба и периодонта
CN110897897B (zh) * 2019-12-11 2021-03-16 四川大学 一种载vegf的壳聚糖温控凝胶及其制备方法和应用
CN113318275B (zh) * 2021-08-03 2021-11-02 首都医科大学附属北京口腔医院 用于牙髓牙本质再生的可降解水凝胶
CN114107184B (zh) * 2021-11-26 2024-10-22 山东中医药大学第二附属医院 一种siRNA在牙髓干细胞成骨分化中的应用
CN114306717B (zh) * 2021-11-30 2022-07-26 中国科学院南海海洋研究所 一种皮肤创伤修复海洋生物医用材料及其制备方法和应用
CN114558171B (zh) * 2022-04-01 2022-10-14 四川大学 一种牙/骨硬组织修复再生的矿物基质凝胶的制备方法
CN115137878B (zh) * 2022-06-24 2023-12-19 成都世联康健生物科技有限公司 一种bmp7细胞因子在制备促内源性牙髓再生注剂中的应用
CN115161272A (zh) * 2022-08-23 2022-10-11 首都医科大学 一种利用Wnt10a促进间充质干细胞牙向分化的方法及其应用
CN115074324B (zh) * 2022-08-23 2022-11-18 首都医科大学 Wnt3a-Wnt10a生物牙根复合体及其制备方法
CN117379598B (zh) * 2023-07-27 2024-03-22 天津医科大学口腔医院 一种高分子水凝胶及其制备方法和用途
CN117797317A (zh) * 2024-02-29 2024-04-02 四川大学 一种肽微球-壳聚糖复合材料的制备方法及其产品和应用

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2010148229A1 (en) * 2009-06-17 2010-12-23 The Trustees Of Columbia University In The City Of New York Tooth scaffolds
WO2012011610A1 (en) * 2010-07-21 2012-01-26 Kyoto University Method for inducing differentiation of human pluripotent stem cell into intermediate mesoderm cell

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2211752A4 (en) * 2007-10-25 2013-10-02 Univ Columbia BIOPULPA
WO2012034070A1 (en) * 2010-09-09 2012-03-15 The Board Of Trustees Of The Leland Stanford Junior University Use of liposomal wnt compositions to enhance osseointegration
WO2012045097A1 (en) * 2010-10-01 2012-04-05 The Trustees Of Columbia University In The City Of New York Production of dentin, cementum and enamel by cells

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2010148229A1 (en) * 2009-06-17 2010-12-23 The Trustees Of Columbia University In The City Of New York Tooth scaffolds
WO2012011610A1 (en) * 2010-07-21 2012-01-26 Kyoto University Method for inducing differentiation of human pluripotent stem cell into intermediate mesoderm cell

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
See also references of WO2014153548A1 *

Also Published As

Publication number Publication date
EP2976044A1 (en) 2016-01-27
WO2014153548A1 (en) 2014-09-25
CN105228557A (zh) 2016-01-06

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Legal Events

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Extension state: BA ME

RIN1 Information on inventor provided before grant (corrected)

Inventor name: SUN, GUOMING

Inventor name: ZHENG, YING

Inventor name: WANG, SONGLIN

Inventor name: MAO, JEREMY J.

DAX Request for extension of the european patent (deleted)
A4 Supplementary search report drawn up and despatched

Effective date: 20161024

RIC1 Information provided on ipc code assigned before grant

Ipc: A61L 27/24 20060101ALI20161018BHEP

Ipc: A61L 27/54 20060101ALI20161018BHEP

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