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EP1572987A4 - Acides nucleiques et polypeptides - Google Patents

Acides nucleiques et polypeptides

Info

Publication number
EP1572987A4
EP1572987A4 EP01907128A EP01907128A EP1572987A4 EP 1572987 A4 EP1572987 A4 EP 1572987A4 EP 01907128 A EP01907128 A EP 01907128A EP 01907128 A EP01907128 A EP 01907128A EP 1572987 A4 EP1572987 A4 EP 1572987A4
Authority
EP
European Patent Office
Prior art keywords
polypeptides
nucleic acids
novel nucleic
novel
acids
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP01907128A
Other languages
German (de)
English (en)
Other versions
EP1572987A2 (fr
Inventor
Y Tom Tang
Chenghua Liu
Radoje T Drmanac
Vinod Asundi
Ping Zhou
Chongjun Xu
Yicheng Cao
Yunquing Ma
Qing A Zhao
Dunrui Wang
Jian-Rui Wang
Jie Zhang
Feiyan Ren
Rui-Hong Chen
Zhi Wei Wang
Aidong J Xue
Yonghong Yang
Tom Wejhrman
Ryle Goodrich
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Nuvelo Inc
Original Assignee
Nuvelo Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US09/728,422 external-priority patent/US20020128187A1/en
Application filed by Nuvelo Inc filed Critical Nuvelo Inc
Publication of EP1572987A2 publication Critical patent/EP1572987A2/fr
Publication of EP1572987A4 publication Critical patent/EP1572987A4/fr
Withdrawn legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
    • C12N9/50—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
    • C12N9/64—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue
    • C12N9/6421—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue from mammals
    • C12N9/6424—Serine endopeptidases (3.4.21)
    • C12N9/6432—Coagulation factor Xa (3.4.21.6)
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/52—Cytokines; Lymphokines; Interferons
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/16—Hydrolases (3) acting on ester bonds (3.1)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y304/00—Hydrolases acting on peptide bonds, i.e. peptidases (3.4)
    • C12Y304/21—Serine endopeptidases (3.4.21)
    • C12Y304/21006—Coagulation factor Xa (3.4.21.6)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Medicinal Chemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biophysics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Toxicology (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
EP01907128A 2000-02-03 2001-02-05 Acides nucleiques et polypeptides Withdrawn EP1572987A4 (fr)

Applications Claiming Priority (17)

Application Number Priority Date Filing Date Title
US728422 1991-07-11
US49691400A 2000-02-03 2000-02-03
US496914 2000-02-03
US56087500A 2000-04-27 2000-04-27
US560875 2000-04-27
US59807500A 2000-06-20 2000-06-20
US598075 2000-06-20
US62032500A 2000-07-19 2000-07-19
US620325 2000-07-19
US65493600A 2000-09-01 2000-09-01
US654936 2000-09-01
US66356100A 2000-09-15 2000-09-15
US663561 2000-09-15
US69332500A 2000-10-20 2000-10-20
US693325 2000-10-20
US09/728,422 US20020128187A1 (en) 2000-02-03 2000-11-30 Novel nucleic acids and polypeptides
PCT/US2001/004098 WO2001057190A2 (fr) 2000-02-03 2001-02-05 Acides nucleiques et polypeptides

Publications (2)

Publication Number Publication Date
EP1572987A2 EP1572987A2 (fr) 2005-09-14
EP1572987A4 true EP1572987A4 (fr) 2005-11-30

Family

ID=27575454

Family Applications (1)

Application Number Title Priority Date Filing Date
EP01907128A Withdrawn EP1572987A4 (fr) 2000-02-03 2001-02-05 Acides nucleiques et polypeptides

Country Status (4)

Country Link
EP (1) EP1572987A4 (fr)
AU (1) AU2001234944A1 (fr)
CA (1) CA2399776A1 (fr)
WO (1) WO2001057190A2 (fr)

Families Citing this family (160)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20020137890A1 (en) 1997-03-31 2002-09-26 Genentech, Inc. Secreted and transmembrane polypeptides and nucleic acids encoding the same
US7057017B2 (en) 1997-04-16 2006-06-06 Millennium Pharmaceuticals, Inc. Human dickkopf-related protein and nucleic acid molecules and uses therefor
US20030073809A1 (en) 1997-06-16 2003-04-17 Genentech, Inc. Secreted and transmembrane polypeptides and nucleic acids encoding the same
US7446181B2 (en) 1998-01-15 2008-11-04 Millennium Pharmaceuticals, Inc. Antibodies that bind human Dickkopf-1 proteins
US20030149531A1 (en) 2000-12-06 2003-08-07 Hubert Rene S. Serpentine transmembrane antigens expressed in human cancers and uses thereof
US6833438B1 (en) 1999-06-01 2004-12-21 Agensys, Inc. Serpentine transmembrane antigens expressed in human cancers and uses thereof
WO1999062941A2 (fr) 1998-06-01 1999-12-09 Urogenesys, Inc. Nouveaux antigenes transmembranaires du type serpentin exprimes dans des cancers humains et utilisation de ces antigenes
US7264801B2 (en) 1998-08-11 2007-09-04 Genentech, Inc. EG-VEGF nucleic acids and polypeptides and method of use
US20020172678A1 (en) 2000-06-23 2002-11-21 Napoleone Ferrara EG-VEGF nucleic acids and polypeptides and methods of use
US20030003507A1 (en) 1999-06-02 2003-01-02 Genentech, Inc. Compositions and methods for the diagnosis and treatment of tumor
US6344541B1 (en) 1998-09-25 2002-02-05 Amgen Inc. DKR polypeptides
AU2964700A (en) 1999-01-15 2000-08-01 Human Genome Sciences, Inc. Bone marrow-specific protein
US7034132B2 (en) 2001-06-04 2006-04-25 Anderson David W Therapeutic polypeptides, nucleic acids encoding same, and methods of use
CA2383254A1 (fr) * 1999-06-02 2000-12-07 Genentech, Inc. Polypeptides transmembranaires secretes et acides nucleiques codants pour ceux-ci
WO2001014552A1 (fr) * 1999-08-19 2001-03-01 Kurokawa, Kiyoshi Proteine meg-1
US7790861B2 (en) * 1999-09-24 2010-09-07 Philadelphia Health And Education Corporation Prostate cancer-related compositions, methods, and kits based on DNA macroarray proteomics platforms
US20020042062A1 (en) 1999-09-24 2002-04-11 Mark Stearns Prostate cancer-related compositions, methods, and kits based on DNA macroarray proteomics platforms
EP1235844A4 (fr) * 1999-11-12 2005-01-19 Human Genome Sciences Inc 28 proteines humaines secretees
WO2001046454A1 (fr) 1999-12-23 2001-06-28 Cor Therapeutics, Inc. Recepteur p2y12
WO2003048326A2 (fr) * 2001-12-03 2003-06-12 Nuvelo, Inc. Procedes et matieres associes a de nouveaux polypeptides et polynucleotides
CA2399860A1 (fr) 2000-02-11 2001-08-16 Glycozym Aps Udp-galactose : .beta.-d-galactose-r 4-.alpha.-d-galactosyltransferase, .alpha.4gal-t1
JP4342069B2 (ja) * 2000-02-14 2009-10-14 生化学工業株式会社 α１，４−ガラクトース転移酵素およびそれをコードするＤＮＡ
US20020031815A1 (en) * 2000-06-26 2002-03-14 Millennium Pharmaceuticals, Inc. 46619, a novel human beta-ketoacyl synthase and uses thereof
AU6802801A (en) * 2000-03-01 2001-09-24 Genentech Inc Secreted and transmembrane polypeptides and nucleic acids encoding the same
US20020065223A1 (en) * 2000-06-16 2002-05-30 Glucksmann Maria Alexandra 33358, a novel human ankyrin family member and uses thereof
AU2001242750A1 (en) * 2000-03-24 2001-10-03 Takeda Chemical Industries Ltd. Novel protein, process for producing the same and use thereof
EP1268543A2 (fr) * 2000-04-05 2003-01-02 Kirin Beer Kabushiki Kaisha Methodes et materiaux relatifs a de nouveaux polypeptides et polynucleotides du type facteur de croissance des cellules-souches
EP1287124A2 (fr) * 2000-04-18 2003-03-05 Bayer Aktiengesellschaft Regulation de la serine protease semblable a l'epithine humaine
US20030119081A1 (en) * 2001-10-29 2003-06-26 Millennium Pharmaceuticals, Inc. 32235, a human aminotransferase family member and uses therefor
WO2001081586A2 (fr) * 2000-04-26 2001-11-01 Millennium Pharmaceuticals, Inc. 21657, deshydrogenase humaine a chaine courte et ses utilisations
US7510845B2 (en) 2000-05-04 2009-03-31 California Institute Of Technology Assay employing G protein-coupled receptor expressed in dorsal root ganglia
US20030092035A1 (en) 2000-05-04 2003-05-15 Anderson David J. Pain signaling molecules
WO2001085935A2 (fr) * 2000-05-09 2001-11-15 Bayer Aktiengesellschaft Recepteur couple a une proteine g du type du gene 6 de differenciation endotheliale
AU2001263493A1 (en) * 2000-05-26 2001-12-11 Millennium Pharmaceuticals, Inc. 50250, a novel human lipase and uses thereof
CA2414015A1 (fr) * 2000-06-21 2001-12-27 Incyte Genomics, Inc. Recepteurs
AU2001281933A1 (en) * 2000-06-30 2002-01-14 Ingenium Pharmaceuticals Ag Human g protein-coupled receptor igpcr17, and uses therof
WO2002006312A2 (fr) * 2000-07-13 2002-01-24 Novartis Ag Gene associe a une maladie
AU2001278488A1 (en) * 2000-07-25 2002-02-05 Bayer Aktiengesellschaft Regulation of human matriptase-like serine protease
JP2004527210A (ja) 2000-08-02 2004-09-09 ザ ジョンズ ホプキンス ユニバーシティー 内皮細胞発現パターンの評価法
US20020187138A1 (en) * 2000-08-02 2002-12-12 Rachel Meyers 15368, a novel human GTP-releasing factor family member and uses therefor
PT1313762E (pt) * 2000-08-04 2006-11-30 Ludwig Inst Cancer Res Gene supressor
AU2001295454A1 (en) * 2000-08-14 2002-02-25 Bayer Aktiengesellschaft Regulation of human p2y1-like g protein-coupled receptor
EP1688496A3 (fr) * 2000-08-14 2006-08-16 Actimis Pharmaceuticals, Inc., Régulation du récepteur couple aux protéines g du type récepteur p2y1
WO2002014483A2 (fr) * 2000-08-15 2002-02-21 Zymogenetics Inc Adenosine deaminase humaine
US6706513B2 (en) 2000-08-21 2004-03-16 Bristol-Myers Squibb Company Adenosine deaminase homolog
US20030166300A1 (en) * 2000-08-30 2003-09-04 Tang Y. Tom Growth-related inflammatory and immune response protein
US20030224396A1 (en) * 2000-08-30 2003-12-04 Yonghong Xiao Regulation of human aminotransferase-like enzyme
EP1317527A2 (fr) * 2000-09-15 2003-06-11 Institut National De La Sante Et De La Recherche Medicale (Inserm) Genes cellulaires impliques dans l'oncogenese, les produits de ces genes et leurs applications diagnostiques et therapeutiques
US7754435B2 (en) * 2000-09-21 2010-07-13 Philadelphia Health And Education Corporation Prostate cancer-related compositions, methods, and kits based on DNA macroarray proteomics platforms
JP2004524819A (ja) * 2000-10-04 2004-08-19 キュラジェン コーポレイション 新規なタンパク質およびこれをコードする核酸ならびにこれらのタンパク質に対する抗体
WO2002031126A2 (fr) * 2000-10-11 2002-04-18 Bayer Aktiengesellschaft Regulation d'une peptidyl-prolyl cis-trans isomerase de type cyclophiline humaine
AU2001297794A1 (en) 2000-10-19 2002-12-03 Millenium Pharmaceuticals, Inc. Methods and compositions of human proteins and uses thereof.
US20060141453A9 (en) 2000-11-03 2006-06-29 Qun-Yong Zhou Prokineticin polypeptides, related compositions and methods
US20030009017A1 (en) * 2000-11-08 2003-01-09 Leiby Kevin R. 38650, 28472, 5495, 65507, 81588 and 14354 methods and compositions of human proteins and uses thereof
ATE479771T1 (de) * 2000-11-09 2010-09-15 Univ Virginia Menschliche hodenspezifische serin/threonin- kinase
AU2002229011A1 (en) * 2000-11-09 2002-05-21 Glaxo Group Limited Deaminase catalyzing the removal of the cyclopropyl moiety from abacavir-mp
US7312086B2 (en) 2000-12-07 2007-12-25 Bristol-Myers Squibb Company Methods of diagnosing colon adenocarcinoma using the human g-protein coupled receptor hgprbmy23
AU2002232822A1 (en) * 2000-12-21 2002-07-01 Incyte Genomics, Inc. Nucleic acid-associated proteins
US7892730B2 (en) * 2000-12-22 2011-02-22 Sagres Discovery, Inc. Compositions and methods for cancer
US20030148920A1 (en) * 2000-12-27 2003-08-07 Steven Rosen Sulfatases and methods of use thereof
WO2002053719A2 (fr) * 2001-01-04 2002-07-11 Incyte Genomics, Inc. Proteines associees au cytosquelette
JP2005500818A (ja) * 2001-01-05 2005-01-13 インサイト・ゲノミックス・インコーポレイテッド 疾患検出および治療用分子
US6319679B1 (en) * 2001-01-26 2001-11-20 Board Of Regents, The University Of Texas System PAS kinase
US20020115136A1 (en) * 2001-02-07 2002-08-22 Gennady Merkulov Isolated human transporter proteins, nucleic acid molecules encoding human transporter proteins, and uses thereof
AU2002247716A1 (en) * 2001-02-14 2002-08-28 Axaron Bioscience Ag Proteins 7b6 and 11b4 and dna sequences encoding the same
WO2002074913A2 (fr) * 2001-03-16 2002-09-26 Incyte Genomics, Inc. Proteines associees a des acides nucleiques
US20030044813A1 (en) * 2001-03-30 2003-03-06 Old Lloyd J. Cancer-testis antigens
US20020146795A1 (en) * 2001-04-02 2002-10-10 Shiaoping Zhu Isolated human Ras-like proteins, nucleic acid molecules encoding these human Ras-like proteins, and uses thereof
WO2002083921A2 (fr) 2001-04-10 2002-10-24 Agensys, Inc. Acides nucleiques et proteines correspondantes utiles pour la detection et le traitement de divers cancers
US7927597B2 (en) * 2001-04-10 2011-04-19 Agensys, Inc. Methods to inhibit cell growth
US6962811B2 (en) 2001-05-09 2005-11-08 Millennium Pharmaceuticals, Inc. 14715, a human fringe family member nucleic acids and uses therefor
DE60237518D1 (de) 2001-05-29 2010-10-14 Human Cell Systems Inc Testikulärer carnitintransporter und sein gen
CA2449289A1 (fr) 2001-06-05 2002-12-12 Exelixis, Inc. Gfat en tant que modificateurs de la voie p53 et leur procede d'utilisation
EP2000148A1 (fr) * 2001-06-20 2008-12-10 Genentech, Inc. Compositions et procédés pour le traitement et le diagnostic du cancer de la prostate
WO2003000874A2 (fr) * 2001-06-25 2003-01-03 Bayer Aktiengesellschaft Regulation de la proteine kinase serine/threonine humaine nek3
US7494646B2 (en) 2001-09-06 2009-02-24 Agensys, Inc. Antibodies and molecules derived therefrom that bind to STEAP-1 proteins
ES2532757T3 (es) 2001-09-06 2015-03-31 Agensys, Inc. Ácido nucleico y proteína correspondiente denominados STEAP-1 útiles en el tratamiento y la detección de cáncer
ES2276964T3 (es) * 2001-09-24 2007-07-01 Grunenthal Gmbh Procedimiento de screening que utiliza bnpi para diferentes indicaciones.
US7265214B2 (en) 2001-10-19 2007-09-04 Rigel Pharmaceuticals, Inc. Germinal center kinase proteins, compositions and methods of use
AU2002363227A1 (en) 2001-10-31 2003-05-12 Millennium Pharmaceuticals, Inc. Methods for the treatment and diagnosis of tumorigenic and angiogenic disorders using 32616
EP1440169A4 (fr) * 2001-10-31 2005-09-21 Millennium Pharm Inc Procedes et compositions pour le traitement et le diagnostic d'algies utilisant le 57749
DE60220621T2 (de) 2001-11-09 2008-03-06 Proteologics, Inc. Posh Nukleinsäure, Polypeptide und darauf bezogene Verfahren
JP2005511660A (ja) * 2001-12-04 2005-04-28 デヴェロゲン アクチエンゲゼルシャフト フュア エントヴィックルングスビオローギッシェ フォルシュング エネルギー恒常性の調節に関与する、ＰＴＰ１０Ｄ、Ｔｅｃタンパク質チロシンキナーゼおよびＥＤＴＰの相同性タンパク質
WO2003054153A2 (fr) * 2001-12-12 2003-07-03 University Of Cincinnati Polypeptides de l'apyrase et acides nucleiques codant pour ces polypeptides
AU2002361385B2 (en) * 2001-12-18 2009-11-19 Centre National De La Recherche Scientifique Cnrs Novel death associated proteins of the THAP family and related Par4 pathways involved in apoptosis control
US7858297B2 (en) 2001-12-18 2010-12-28 Centre National De La Recherche Scientifique Cnrs Chemokine-binding protein and methods of use
EP1473365A1 (fr) * 2002-02-04 2004-11-03 Takeda Chemical Industries, Ltd. Inhibiteurs d'angiogenese
GB0205112D0 (en) * 2002-03-05 2002-04-17 Pantherix Ltd Enzyme
EP1495806B1 (fr) 2002-03-11 2013-12-04 Japan Science and Technology Agency Catalyseur chiral de zirconium
DE10212397A1 (de) * 2002-03-20 2003-10-16 Universitaetsklinikum Freiburg Repressor der Skelettmuskeldifferenzierung, dafür kodierende Nucleinsäure und dessen Verwendung in Diagnostik und Therapie
JPWO2003086462A1 (ja) * 2002-03-29 2005-08-18 セレスター・レキシコ・サイエンシズ株式会社 ｃ−Ｊｕｎリン酸化阻害剤
US20050202431A1 (en) * 2002-04-01 2005-09-15 National Institute Of Advanced Industrial Science Application of kiaa0172 gene to treatment and diagnosis of diseases and drug discovery
AU2003234274A1 (en) 2002-04-26 2003-11-10 California Institute Of Technology D1-1 nucleic acids, polypeptides and related methods
US7622443B2 (en) 2002-04-26 2009-11-24 California Institute Of Technology Method for inhibiting pro-angiogenic activities of endothelial cells selectively at a site of neoangiogenesis in a mammal by administration of the extracellular domain of D1-1 polypeptides
DE10222845A1 (de) * 2002-05-23 2003-12-04 Dresden Arzneimittel Klonierung, Expression und Charakterisierung der Gesamtsequenz von Phosphodiesterase 8B
CA2491083A1 (fr) * 2002-06-28 2004-01-08 Imclone Systems Incorporated Nouvelles sequences polynucleotidiques et polypeptidiques et leurs utilisations
US7135556B2 (en) 2002-07-19 2006-11-14 Schering Corporation NPC1L1 (NPC3) and methods of use thereof
WO2004009619A2 (fr) * 2002-07-19 2004-01-29 Cellzome Ag Complexes proteiques de la proteine activatrice de la transcription de tip60
JP2004290170A (ja) * 2002-08-02 2004-10-21 Takeda Chem Ind Ltd 疾患関連遺伝子の用途
TW200413725A (en) * 2002-09-30 2004-08-01 Oncotherapy Science Inc Method for diagnosing non-small cell lung cancers
US7056685B1 (en) 2002-11-05 2006-06-06 Amgen Inc. Receptor ligands and methods of modulating receptors
WO2004046342A2 (fr) * 2002-11-20 2004-06-03 Biogen Idec Inc. Nouvelles cibles geniques et ligands se liant a ces cibles dans le traitement et le diagnostic de carcinomes
AU2003300680A1 (en) * 2002-12-10 2004-07-09 Centre National De La Recherche Scientifique Cnrs Thap proteins as nuclear receptors for chemokines and roles in transcriptional regulation, cell proliferation and cell differentiation
JP4140951B2 (ja) * 2002-12-18 2008-08-27 独立行政法人科学技術振興機構 転写制御因子ｚｈｘ３
ATE490323T1 (de) 2002-12-29 2010-12-15 Toudai Tlo Ltd Adiponektin-rezeptor und dafür kodierendes gen
AU2004206250B8 (en) * 2003-01-21 2009-09-17 Bristol-Myers Squibb Company Polynucleotide encoding a novel acyl coenzyme a, monoacylglycerol acyltransferase-3 (MGAT3), and uses thereof
EP1591127B1 (fr) * 2003-02-03 2013-07-24 Japan Science and Technology Agency Régénération et néogenèse de cellules visuelles de la rétine par le gène Otx2
WO2005051988A2 (fr) * 2003-03-03 2005-06-09 Genentech, Inc. Compositions et procedes permettant de traiter un lupus erythemateux systemique
JP2007525183A (ja) * 2003-04-30 2007-09-06 アジェンシス， インコーポレイテッド 癌の処置および検出において有用な１０９ｐ１ｄ４と称される、核酸および対応タンパク質
WO2004104218A1 (fr) * 2003-05-23 2004-12-02 Bayer Healthcare Ag Agents diagnostiques et therapeutiques destines a des maladies associees a x-prolyl aminopeptidase 1 (xpnpep1)
WO2005023855A2 (fr) * 2003-09-10 2005-03-17 Friedrich-Alexander-Uni- Versitatet Erlangen- Nuernberg Gene et proteine k203
US7534562B2 (en) * 2003-09-30 2009-05-19 Daiichi Pharmaceutical Co., Ltd. Tetrahydrofolate synthetase gene
WO2005059504A2 (fr) * 2003-12-12 2005-06-30 Bayer Healthcare Ag Diagnostics et therapeutique destines au traitement de maladies associees au recepteur couple aux proteines g gpr34 (gpr34)
WO2005069900A2 (fr) 2004-01-16 2005-08-04 Merck & Co., Inc. Npc1l1 (npc3) et procédés pour identifier des ligands de ceux-ci
JP2007521835A (ja) * 2004-02-10 2007-08-09 トラスティーズ・オブ・ダートマウス・カレッジ ニコチンアミドリボシドキナーゼ組成物およびそれらの使用方法
US8010189B2 (en) 2004-02-20 2011-08-30 Brainsgate Ltd. SPG stimulation for treating complications of subarachnoid hemorrhage
US8055347B2 (en) 2005-08-19 2011-11-08 Brainsgate Ltd. Stimulation for treating brain events and other conditions
US9233245B2 (en) 2004-02-20 2016-01-12 Brainsgate Ltd. SPG stimulation
JP4773424B2 (ja) * 2004-03-19 2011-09-14 イエール ユニバーシティ レナラーゼ（モノアミンオキシダーゼｃ）の検出、単離及び使用
WO2005095450A2 (fr) 2004-03-30 2005-10-13 Nsgene A/S Utilisation therapeutique d'un facteur de croissance, nsg33
US20050222040A1 (en) * 2004-04-05 2005-10-06 Blm Group, Inc. Vertebrate peptide modulators of lipid metabolism
CN101258166B (zh) 2004-04-22 2013-01-30 阿根西斯公司 与steap-1蛋白结合的抗体及其衍生的分子
MX2007001221A (es) 2004-08-04 2007-03-23 Amgen Inc Anticuerpos para proteina dickkopf-1 (dkk-1).
WO2006069592A2 (fr) * 2004-12-31 2006-07-06 Vereniging Voor Christelijk Hoger Onderwijs, Wetenschappelijk Onderzoek En Patientenzorg Methode permettant de diagnostiquer et/ou de predire la toxemie preeclamptique et/ou des troubles associes
FI20050011A (fi) * 2005-01-05 2006-07-06 Jurilab Ltd Oy Menetelmä ja testipakkaus tyypin 2 diabetes mellituksen riskin havaitsemiseksi
WO2006074914A2 (fr) * 2005-01-13 2006-07-20 Novartis Forschungsstiftung, Zweigniederlassung Friedrich Miescher Institute For Biomedical Research Helicase d'arn humaine et ses utilisations therapeutiques
US7521195B1 (en) 2005-07-21 2009-04-21 Celera Corporation Lung disease targets and uses thereof
AU2006315299A1 (en) 2005-11-21 2007-05-24 Yale University Methods of regulating renalase (Monoamine Oxidase C)
US9206242B2 (en) * 2005-11-22 2015-12-08 National University Corporation Nagoya University Application of actin-binding protein to disease associated with cell motility
US7910698B2 (en) 2006-02-24 2011-03-22 Schering Corporation NPC1L1 orthologues
PT2845866T (pt) 2006-10-27 2017-08-09 Genentech Inc Anticorpos e imunoconjugados e utilizações dos mesmos
WO2008136541A1 (fr) * 2007-05-02 2008-11-13 Snu R&Db Foundation Inhibiteur de l'angiogenèse comprenant de la météorine en tant que principe actif
WO2009005809A2 (fr) 2007-07-02 2009-01-08 Oncomed Pharmaceuticals, Inc. Compositions et procédés de traitement et de diagnostic d'un cancer
EP2170374A2 (fr) * 2007-07-03 2010-04-07 Andreas Reichert Procédé de traitement de maladies liées à un dysfonctionnement mitochondrial
US20100204128A1 (en) * 2007-07-24 2010-08-12 Sanare Investment As Novel peptides
US8551779B2 (en) 2007-12-28 2013-10-08 Novo Nordisk A/S DDR1-mediated cell purification of pancreatic endocrine cells through their progenitors
US8334264B2 (en) 2008-07-24 2012-12-18 NsGenee A/S Therapeutic use of a growth factor, METRNL
EP2408905B1 (fr) 2009-03-16 2017-05-10 Pangu Biopharma Limited Compositions et procedes comprenant des variants d'epissage d'histidyl-arnt synthetase presentant des activites biologiques non canoniques
AR075989A1 (es) 2009-04-10 2011-05-11 Lilly Co Eli Anticuerpo dkk -1 (dickkopf-1) humano disenado por ingenieria
US8815779B2 (en) 2009-09-16 2014-08-26 SwitchGear Genomics, Inc. Transcription biomarkers of biological responses and methods
KR101884028B1 (ko) 2009-11-30 2018-08-01 제넨테크, 인크. Ｓｌｃ３４ａ２ (ｔａｔ２１１ = 서열 ２)를 발현하는 종양의 치료 및 진단을 위한 항체
EP2939689B1 (fr) 2009-12-11 2017-09-13 aTyr Pharma, Inc. Glutaminyl ARNt synthétases pour leur utilisation dans le traitement de maladies inflammatoires
AU2011248100B2 (en) 2010-05-04 2017-01-19 Pangu Biopharma Limited Innovative discovery of therapeutic, diagnostic, and antibody compositions related to protein fragments of glutamyl-prolyl-tRNA synthetases
EA030418B1 (ru) 2010-07-12 2018-08-31 ЭйТИР ФАРМА, ИНК. ТЕРАПЕВТИЧЕСКАЯ КОМПОЗИЦИЯ И СПОСОБ ДЛЯ ЛЕЧЕНИЯ ВОСПАЛИТЕЛЬНОГО ЗАБОЛЕВАНИЯ, ПОЛИПЕПТИД АМИНОАЦИЛ-тРНК-СИНТЕТАЗЫ (AARS)
KR101886029B1 (ko) 2010-10-01 2018-08-07 호바 세라퓨틱스 에이피에스 무해자극통증, 통각과민증, 자발통증 및 헛통증의 치료를 위한 메테오린의 용도
EP2731625B1 (fr) 2011-07-15 2018-04-18 OncoMed Pharmaceuticals, Inc. Agents de fixation aux protéines rspo et leurs utilisations
KR102075881B1 (ko) 2011-09-05 2020-02-11 호바 세라퓨틱스 에이피에스 이질통, 통각과민증, 자발통 및 환상통의 치료
CA2864300A1 (fr) 2012-02-16 2013-08-22 Atyr Pharma, Inc. Histidyl-arnt synthetases pour le traitement de maladies auto-immunes et inflammatoires
SG11201500233PA (en) 2012-07-13 2015-04-29 Oncomed Pharm Inc Rspo3 binding agents and uses thereof
EP2742935A1 (fr) * 2012-12-14 2014-06-18 Tissue Med Biosciences Forschungs- und Entwicklungsgesellschaft mbH SERF2 pour traiter l'atrophie ou augmenter la croissance cellulaire
CN114717206A (zh) 2013-03-15 2022-07-08 Atyr 医药公司 组氨酰-trna合成酶-fc缀合物
EP2878335B1 (fr) 2013-11-10 2018-01-03 Brainsgate Ltd. Implant et système d'implantation pour stimulateur neural
WO2016044295A1 (fr) 2014-09-16 2016-03-24 Oncomed Pharmaceuticals, Inc. Traitement de maladies fibrotiques
US10271907B2 (en) 2015-05-13 2019-04-30 Brainsgate Ltd. Implant and delivery system for neural stimulator
WO2018102672A1 (fr) 2016-12-04 2018-06-07 Alavi Khorassani Moghadam Marcel Victor Méthodes de traitement de maladies associées au stress mitochondrial
US10905766B2 (en) * 2017-03-23 2021-02-02 Oregon State University Therapeutic compositions and methods for treatment of muscle wasting diseases
CN110494452B (zh) 2017-04-03 2023-08-25 豪夫迈·罗氏有限公司 结合steap-1的抗体
CA3060514A1 (fr) 2017-04-20 2018-10-25 Atyr Pharma, Inc. Compositions et procedes pour le traitement d'inflammation pulmonaire
CN110910960B (zh) * 2019-11-30 2022-07-08 浙江天科高新技术发展有限公司 一种鲍曼不动杆菌分子血清型快速分析方法
CN116685344A (zh) * 2020-12-08 2023-09-01 想象制药有限责任公司 治疗伤口的组合物和方法

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1998049306A1 (fr) * 1997-04-29 1998-11-05 Incyte Pharmaceuticals, Inc. Lectine humaine de type c
WO1998054209A2 (fr) * 1997-05-31 1998-12-03 Peptide Therapeutics Limited Mafa humaine

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5474796A (en) * 1991-09-04 1995-12-12 Protogene Laboratories, Inc. Method and apparatus for conducting an array of chemical reactions on a support surface

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1998049306A1 (fr) * 1997-04-29 1998-11-05 Incyte Pharmaceuticals, Inc. Lectine humaine de type c
WO1998054209A2 (fr) * 1997-05-31 1998-12-03 Peptide Therapeutics Limited Mafa humaine

Non-Patent Citations (13)

* Cited by examiner, † Cited by third party
Title
DATABASE EBI 1 November 1996 (1996-11-01), XP002329122, retrieved from EBI Database accession no. Q04490 *
DATABASE EMBL [online] 15 November 1992 (1992-11-15), "Homo Sapiens P5-1 mRNA, complete cds.", XP002329509, retrieved from EBI Database accession no. HSMHP *
DATABASE EMBL [online] 19 January 1998 (1998-01-19), "nx26e06.s1 NCI_CGAP_GC4 Homo sapiens cDNA clone IMAGE:1257250 3', mRNA sequence.", XP002346073, retrieved from EBI Database accession no. AA742567 *
DATABASE EMBL [online] 25 January 1999 (1999-01-25), "CITBI-E1-2541D22.TR CITBI-E1 Homo sapiens genomic clone 2541D22, genomic survey sequence.", XP002346074, retrieved from EBI Database accession no. AQ356422 *
DATABASE EMBL [online] 27 August 1998 (1998-08-27), "Homo sapiens PAC clone RP4-701O16 from 7, complete sequence.", XP002346072, retrieved from EBI Database accession no. AC005531 *
DATABASE EMBL [online] 4 December 1998 (1998-12-04), "Homo sapiens DNA, P5-1-hom region.", XP002329406, retrieved from EBI Database accession no. D88650 *
DATABASE EMBL 21 April 1994 (1994-04-21), "H.sapiens P5-1g DNA", XP002329407, retrieved from EBI Database accession no. Z31714 *
DATABASE EMBL 30 June 1999 (1999-06-30), "wi73f11.x1 NCI_CGAP_Kid12 Homo sapiens cDNA clone IMAGE:2398989 3' similar to TR:Q04490 Q04490 P5-1 PROTEIN.", XP002329408, retrieved from EBI Database accession no. AI765329 *
DATABASE UniProt 1 June 1998 (1998-06-01), "Mast cell function-associated antigen", XP002346076, retrieved from EBI Database accession no. O43198 *
DATABASE UniProt 1 November 1998 (1998-11-01), "ITIM-containing receptor MAFA_l (Mast cell function-associated antigen homolog)", XP002346075, retrieved from EBI Database accession no. 075613 *
See also references of WO0157190A3 *
SHIINA TAKASHI ET AL.: "Physical mapping between the S and HLA-E genes in the human MHC class I region: Construction of a BAC, PAC, and cosmid contig", IMMUNOGENETICS, vol. 48, no. 6, November 1998 (1998-11-01), pages 402 - 407, XP002329404, ISSN: 0093-7711 *
VERNET C. ET AL.: "A novel coding sequence belonging to a new multicopy gene family mapping within the human MHC class I region", IMMUNOGENETICS, vol. 38, no. 1, 1993, pages 47 - 53, XP002904811, ISSN: 0093-7711 *

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AU2001234944A1 (en) 2001-08-14
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