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EP1137659A4 - Hemmung von angiogenese durch hochmolekulares kininogen und peptidanaloga davon - Google Patents

Hemmung von angiogenese durch hochmolekulares kininogen und peptidanaloga davon

Info

Publication number
EP1137659A4
EP1137659A4 EP99962723A EP99962723A EP1137659A4 EP 1137659 A4 EP1137659 A4 EP 1137659A4 EP 99962723 A EP99962723 A EP 99962723A EP 99962723 A EP99962723 A EP 99962723A EP 1137659 A4 EP1137659 A4 EP 1137659A4
Authority
EP
European Patent Office
Prior art keywords
angiogenesis
inhibition
molecular weight
high molecular
peptide analogs
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP99962723A
Other languages
English (en)
French (fr)
Other versions
EP1137659A1 (de
Inventor
R Keith Mccrae
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Temple University of Commonwealth System of Higher Education
Original Assignee
Temple University of Commonwealth System of Higher Education
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Temple University of Commonwealth System of Higher Education filed Critical Temple University of Commonwealth System of Higher Education
Publication of EP1137659A1 publication Critical patent/EP1137659A1/de
Publication of EP1137659A4 publication Critical patent/EP1137659A4/de
Withdrawn legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04—Linear peptides containing only normal peptide links
    • C07K7/08—Linear peptides containing only normal peptide links having 12 to 20 amino acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/81—Protease inhibitors
    • C07K14/8107—Endopeptidase (E.C. 3.4.21-99) inhibitors
    • C07K14/8139—Cysteine protease (E.C. 3.4.22) inhibitors, e.g. cystatin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Ophthalmology & Optometry (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
EP99962723A 1998-11-10 1999-11-05 Hemmung von angiogenese durch hochmolekulares kininogen und peptidanaloga davon Withdrawn EP1137659A4 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US10783398P 1998-11-10 1998-11-10
US107833P 1998-11-10
PCT/US1999/026419 WO2000027866A1 (en) 1998-11-10 1999-11-05 Inhibition of angiogenesis by high molecular weight kininogen and peptide analogs thereof

Publications (2)

Publication Number Publication Date
EP1137659A1 EP1137659A1 (de) 2001-10-04
EP1137659A4 true EP1137659A4 (de) 2005-08-10

Family

ID=22318715

Family Applications (1)

Application Number Title Priority Date Filing Date
EP99962723A Withdrawn EP1137659A4 (de) 1998-11-10 1999-11-05 Hemmung von angiogenese durch hochmolekulares kininogen und peptidanaloga davon

Country Status (8)

Country Link
EP (1) EP1137659A4 (de)
JP (1) JP2002529474A (de)
AU (1) AU773862B2 (de)
CA (1) CA2350915A1 (de)
IL (1) IL142822A0 (de)
NZ (1) NZ511618A (de)
WO (1) WO2000027866A1 (de)
ZA (1) ZA200104130B (de)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6994852B1 (en) 1999-11-12 2006-02-07 Temple University-Of The Commonwealth System Of Higher Education Inhibition of angiogenesis by antibodies against high molecular weight kininogen domain 5
WO2001034195A1 (en) * 1999-11-12 2001-05-17 Temple University Of The Commonwealth System Of Higher Education Inhibition of angiogenesis by antibodies against high molecular weight kininogen domain 5
AU2001277119A1 (en) * 2000-07-24 2002-02-25 Attenuon, Llc Human kininogen d5 domain polypeptides and their use
WO2004024877A2 (en) * 2002-09-13 2004-03-25 Attenuon, Llc Human kininogen d3 domain polypeptide as an anti-angiogenic and anti-tumor agent
SE0301431D0 (sv) 2003-05-19 2003-05-19 Dermagen Novel antimicrobial peptides
GB0821721D0 (en) * 2008-11-27 2008-12-31 Hansa Medical Ab Antimicrobial therapy
CN104211807B (zh) * 2014-08-22 2017-10-20 北京蛋白质组研究中心 一种抗两种多肽的单克隆抗体及其制备方法和应用
CN104155457B (zh) * 2014-08-22 2016-11-16 北京蛋白质组研究中心 一种结直肠癌相关“多肽-蛋白组合式标志物”检测试剂盒

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5596079A (en) * 1991-12-16 1997-01-21 Smith; James R. Mimetics of senescent cell derived inhibitors of DNA synthesis
US5756291A (en) * 1992-08-21 1998-05-26 Gilead Sciences, Inc. Aptamers specific for biomolecules and methods of making
JPH0782172A (ja) * 1993-09-17 1995-03-28 Hoechst Japan Ltd 創傷治療剤
DE69523750T2 (de) * 1994-05-04 2002-08-01 Mount Sinai Hospital Corp., Toronto Modulatoren der cytokine der tgf-beta überfamilie und verfahren zu ihrer bestimmung
JPH08208692A (ja) * 1994-09-28 1996-08-13 Sumitomo Pharmaceut Co Ltd 新規な細胞接着抑制ペプチド誘導体
EP0808627A2 (de) * 1996-05-22 1997-11-26 Hoechst Aktiengesellschaft Verwendung nicht-peptidischer Bradykinin-Antagonisten zur Behandlung und Prävention von chronisch-fibrogenetischen Lebererkrankungen, akuten Lebererkrankungen und den damit verbundenen Komplikationen
CA2187728A1 (en) * 1996-05-29 1997-11-29 Mary Lou Guerinot Iron-regulated metal transporters and uses therefor

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
No further relevant documents disclosed *

Also Published As

Publication number Publication date
NZ511618A (en) 2003-06-30
CA2350915A1 (en) 2000-05-18
ZA200104130B (en) 2002-05-21
AU773862B2 (en) 2004-06-10
JP2002529474A (ja) 2002-09-10
EP1137659A1 (de) 2001-10-04
WO2000027866A1 (en) 2000-05-18
IL142822A0 (en) 2002-03-10
AU1910600A (en) 2000-05-29

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Legal Events

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Effective date: 20010531

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RAP1 Party data changed (applicant data changed or rights of an application transferred)

Owner name: TEMPLE UNIVERSITY OF THE COMMONWEALTH SYSTEM OF HI

RIC1 Information provided on ipc code assigned before grant

Ipc: 7C 07K 14/47 B

Ipc: 7C 07K 7/08 B

Ipc: 7A 61K 38/36 B

Ipc: 7A 61K 38/08 B

Ipc: 7A 61K 38/07 B

Ipc: 7C 07K 5/10 B

Ipc: 7C 07K 14/745 B

Ipc: 7C 12Q 1/68 B

Ipc: 7C 07K 7/00 B

Ipc: 7G 01N 33/53 B

Ipc: 7A 61K 31/47 B

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Effective date: 20050622

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