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EG24407A - Carboxyaryl substituted diphenyl ureas as raf kinase inhibitors - Google Patents

Carboxyaryl substituted diphenyl ureas as raf kinase inhibitors

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Publication number
EG24407A
EG24407A EG20000039A EG20000039A EG24407A EG 24407 A EG24407 A EG 24407A EG 20000039 A EG20000039 A EG 20000039A EG 20000039 A EG20000039 A EG 20000039A EG 24407 A EG24407 A EG 24407A
Authority
EG
Egypt
Prior art keywords
kinase inhibitors
raf kinase
substituted diphenyl
diphenyl ureas
carboxyaryl substituted
Prior art date
Application number
EG20000039A
Inventor
Bernd Riedl
Jacques Dumas
Uday Khire
Timothy B Lowinger
William J Scott
Roger A Smith
Jill E Wood
Mary-Katherin Monahan
Reina Natero
Joel Renick
Robert N Sibley
Original Assignee
Bayer Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=27381740&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=EG24407(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Bayer Corp filed Critical Bayer Corp
Application granted granted Critical
Publication of EG24407A publication Critical patent/EG24407A/en

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    • C07D295/16Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms
    • C07D295/18Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms by radicals derived from carboxylic acids, or sulfur or nitrogen analogues thereof
    • C07D295/182Radicals derived from carboxylic acids
    • C07D295/192Radicals derived from carboxylic acids from aromatic carboxylic acids
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    • C07D211/68Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
    • C07D211/72Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D211/78Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
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    • A61K31/4427Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
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    • A61K31/445Non condensed piperidines, e.g. piperocaine
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EG20000039A 1999-01-13 2000-01-15 Carboxyaryl substituted diphenyl ureas as raf kinase inhibitors EG24407A (en)

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