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EE200000573A - Asendatud indoolalkaanhapped - Google Patents

Asendatud indoolalkaanhapped

Info

Publication number
EE200000573A
EE200000573A EEP200000573A EEP200000573A EE200000573A EE 200000573 A EE200000573 A EE 200000573A EE P200000573 A EEP200000573 A EE P200000573A EE P200000573 A EEP200000573 A EE P200000573A EE 200000573 A EE200000573 A EE 200000573A
Authority
EE
Estonia
Prior art keywords
indolealkanoic acids
substituted
substituted indolealkanoic
acids
indolealkanoic
Prior art date
Application number
EEP200000573A
Other languages
English (en)
Inventor
L. Jones Michael
Gunn David
Howard Jones John
C. Van Zandt Michael
Original Assignee
The Institutes For Pharmaceutical Discovery, Llc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by The Institutes For Pharmaceutical Discovery, Llc filed Critical The Institutes For Pharmaceutical Discovery, Llc
Publication of EE200000573A publication Critical patent/EE200000573A/et

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D417/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/06Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00Drugs for disorders of the urinary system
    • A61P13/12Drugs for disorders of the urinary system of the kidneys
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/02Drugs for disorders of the nervous system for peripheral neuropathies
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00Drugs for disorders of the senses
    • A61P27/02Ophthalmic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00Drugs for disorders of the senses
    • A61P27/02Ophthalmic agents
    • A61P27/12Ophthalmic agents for cataracts
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/08Drugs for disorders of the metabolism for glucose homeostasis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/08Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/10Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D209/00Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04Indoles; Hydrogenated indoles
    • C07D209/10Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring

Landscapes

  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Diabetes (AREA)
  • Obesity (AREA)
  • Hematology (AREA)
  • Ophthalmology & Optometry (AREA)
  • Neurosurgery (AREA)
  • Urology & Nephrology (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Emergency Medicine (AREA)
  • Endocrinology (AREA)
  • Vascular Medicine (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Indole Compounds (AREA)
EEP200000573A 1998-03-31 1999-03-31 Asendatud indoolalkaanhapped EE200000573A (et)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US8014398P 1998-03-31 1998-03-31
PCT/US1999/007116 WO1999050268A2 (en) 1998-03-31 1999-03-31 Substituted indolealkanoic acids

Publications (1)

Publication Number Publication Date
EE200000573A true EE200000573A (et) 2002-04-15

Family

ID=22155536

Family Applications (1)

Application Number Title Priority Date Filing Date
EEP200000573A EE200000573A (et) 1998-03-31 1999-03-31 Asendatud indoolalkaanhapped

Country Status (29)

Country Link
US (9) US6214991B1 (et)
EP (1) EP1066283B1 (et)
JP (2) JP3494990B2 (et)
KR (1) KR100584650B1 (et)
CN (1) CN1205207C (et)
AP (1) AP2000001929A0 (et)
AT (1) ATE269861T1 (et)
AU (1) AU774929B2 (et)
BG (1) BG65446B1 (et)
BR (1) BR9909358A (et)
CA (1) CA2383983C (et)
CZ (1) CZ300706B6 (et)
DE (1) DE69918278T2 (et)
EE (1) EE200000573A (et)
ES (1) ES2224632T3 (et)
HU (1) HUP0101672A3 (et)
ID (1) ID27884A (et)
IL (2) IL138711A0 (et)
MX (1) MXPA02003122A (et)
NO (1) NO20004900L (et)
NZ (1) NZ507172A (et)
OA (1) OA11622A (et)
PL (1) PL201645B1 (et)
SK (1) SK7522001A3 (et)
TR (1) TR200002869T2 (et)
TW (1) TWI243163B (et)
WO (1) WO1999050268A2 (et)
YU (1) YU59600A (et)
ZA (1) ZA200005577B (et)

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AU5960300A (en) * 1999-07-15 2001-02-05 Nps Allelix Corp. Heterocyclic compounds for the treatment of migraine
AU2001238718A1 (en) * 2000-03-02 2001-09-12 The Institutes For Pharmaceutical Discovery, Llc Compositions containing a substituted indolealkanoic acid and an angiotensin converting enzyme inhibitor
AU2001259668A1 (en) * 2000-05-09 2001-11-20 The Institute For Pharmaceutical Discovery Llc Methods for testing compounds useful for treating diabetic complications
JP2004517851A (ja) 2000-12-27 2004-06-17 バイエル アクチェンゲゼルシャフト 甲状腺受容体のリガンドとしてのインドール誘導体
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ATE356623T1 (de) 2002-01-18 2007-04-15 Aryx Therapeutics 5-ht3-rezeptorantagonisten und verwendungsverfahren
AU2003256926A1 (en) * 2002-07-26 2004-02-16 The Institutes For Pharmaceutical Discovery, Llc Substituted indolealkanoic acids derivative and formulations containing same for use in treatment of diabetic complications
CA2395871A1 (en) * 2002-07-26 2004-01-26 The Institutes For Pharmaceutical Discovery, Llc Substituted indolealkanoic acids derivatives and formulations containing same for use in treatment of diabetic complications
US7186746B2 (en) * 2002-08-29 2007-03-06 Merck & Co., Inc. Indoles having anti-diabetic activity
ES2268480T3 (es) 2002-12-10 2007-03-16 Wyeth Derivados del acido 3-alquilo- y 3-arilalquilo-1h-indol-1-il-acetico sustituidos como inhibidores del inhibidor del activador del plasminogeno-1 (pai-1).
UA80453C2 (en) 2002-12-10 2007-09-25 Derivatives of substituted dyhydropyranoindol-3,4-dion as inhibitors of plasminogen activator inhibitor-1 (pai-1)
CA2509238A1 (en) 2002-12-10 2004-06-24 Wyeth Substituted 3-carbonyl-1h-indol-1-yl acetic acid derivatives as inhibitors of plasminogen activator inhibitor-1 (pai-1)
JP2006510672A (ja) 2002-12-10 2006-03-30 ワイス プラスミノーゲン活性化因子の阻害因子−1(pai−1)の阻害剤としての置換インドールオキソ−アセチルアミノ酢酸誘導体
DK1569901T3 (da) 2002-12-10 2009-02-16 Wyeth Corp Aryl-, aryloxy- og alkoxysubstituerede 1H-indol-3-yl-glyoxylsyrederivater som inhibitorer af plasminogenaktivatorinhibitor-1 (PAI-1)
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CN1812977A (zh) * 2003-04-30 2006-08-02 药物研发有限责任公司 取代羧酸
KR20060054410A (ko) * 2003-08-01 2006-05-22 제네랩스 테크놀로지스, 인코포레이티드 플라비비리다에에 대한 2고리 이미다졸 유도체
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US7332521B2 (en) 2003-09-25 2008-02-19 Wyeth Substituted indoles
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US7446201B2 (en) 2003-09-25 2008-11-04 Wyeth Substituted heteroaryl benzofuran acids
US7268159B2 (en) 2003-09-25 2007-09-11 Wyeth Substituted indoles
US7265148B2 (en) 2003-09-25 2007-09-04 Wyeth Substituted pyrrole-indoles
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US7351726B2 (en) 2003-09-25 2008-04-01 Wyeth Substituted oxadiazolidinediones
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AU2001238718A1 (en) * 2000-03-02 2001-09-12 The Institutes For Pharmaceutical Discovery, Llc Compositions containing a substituted indolealkanoic acid and an angiotensin converting enzyme inhibitor

Also Published As

Publication number Publication date
US20010016661A1 (en) 2001-08-23
JP3494990B2 (ja) 2004-02-09
US7659269B2 (en) 2010-02-09
ZA200005577B (en) 2002-02-11
CZ20003607A3 (cs) 2001-03-14
JP2002509931A (ja) 2002-04-02
AU3459599A (en) 1999-10-18
PL201645B1 (pl) 2009-04-30
US20070093530A1 (en) 2007-04-26
JP2003155274A (ja) 2003-05-27
CZ300706B6 (cs) 2009-07-22
US20080214540A1 (en) 2008-09-04
BR9909358A (pt) 2000-12-12
US20030018053A1 (en) 2003-01-23
CN1296485A (zh) 2001-05-23
NO20004900L (no) 2000-10-17
US6426344B2 (en) 2002-07-30
DE69918278D1 (de) 2004-07-29
WO1999050268A3 (en) 1999-12-16
SK7522001A3 (en) 2002-02-05
ES2224632T3 (es) 2005-03-01
KR100584650B1 (ko) 2006-05-30
US20100137301A1 (en) 2010-06-03
OA11622A (en) 2004-09-16
US20120270912A1 (en) 2012-10-25
US6214991B1 (en) 2001-04-10
PL348244A1 (en) 2002-05-20
ID27884A (id) 2001-05-03
CA2383983C (en) 2009-09-29
BG65446B1 (bg) 2008-08-29
TR200002869T2 (tr) 2000-12-21
HUP0101672A2 (hu) 2002-04-29
MXPA02003122A (es) 2004-04-21
HUP0101672A3 (en) 2002-05-28
EP1066283B1 (en) 2004-06-23
AP2000001929A0 (en) 2000-09-30
IL138711A (en) 2006-09-05
TWI243163B (en) 2005-11-11
US7304079B2 (en) 2007-12-04
EP1066283A2 (en) 2001-01-10
ATE269861T1 (de) 2004-07-15
US7105514B2 (en) 2006-09-12
WO1999050268A2 (en) 1999-10-07
BG104819A (en) 2001-05-31
US20040235933A1 (en) 2004-11-25
US20100324039A1 (en) 2010-12-23
NO20004900D0 (no) 2000-09-29
CN1205207C (zh) 2005-06-08
YU59600A (sh) 2002-12-10
US6730794B2 (en) 2004-05-04
CA2383983A1 (en) 1999-10-07
AU774929B2 (en) 2004-07-15
DE69918278T2 (de) 2005-07-14
IL138711A0 (en) 2001-10-31
NZ507172A (en) 2003-10-31
US8163932B2 (en) 2012-04-24
KR20010042330A (ko) 2001-05-25

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