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ECSP034868A - Cápsulas para inhalación - Google Patents

Cápsulas para inhalación

Info

Publication number
ECSP034868A
ECSP034868A EC2003004868A ECSP034868A ECSP034868A EC SP034868 A ECSP034868 A EC SP034868A EC 2003004868 A EC2003004868 A EC 2003004868A EC SP034868 A ECSP034868 A EC SP034868A EC SP034868 A ECSP034868 A EC SP034868A
Authority
EC
Ecuador
Prior art keywords
capsules
inhalation capsules
inhalation
inhalets
contain
Prior art date
Application number
EC2003004868A
Other languages
English (en)
Inventor
Michael Trunk
Michael Walz
Dieter Hochrainer
Karoline Bechtold-Peters
Original Assignee
Boehringer Ingelheim Pharma
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=7687020&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ECSP034868(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Boehringer Ingelheim Pharma filed Critical Boehringer Ingelheim Pharma
Publication of ECSP034868A publication Critical patent/ECSP034868A/es

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/48Preparations in capsules, e.g. of gelatin, of chocolate
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/007Pulmonary tract; Aromatherapy
    • A61K9/0073Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
    • A61K9/0075Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy for inhalation via a dry powder inhaler [DPI], e.g. comprising micronized drug mixed with lactose carrier particles
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445Non condensed piperidines, e.g. piperocaine
    • A61K31/451Non condensed piperidines, e.g. piperocaine having a carbocyclic group directly attached to the heterocyclic ring, e.g. glutethimide, meperidine, loperamide, phencyclidine, piminodine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445Non condensed piperidines, e.g. piperocaine
    • A61K31/4523Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/48Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4816Wall or shell material
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M11/00Sprayers or atomisers specially adapted for therapeutic purposes
    • A61M11/001Particle size control
    • A61M11/003Particle size control by passing the aerosol trough sieves or filters
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00Inhalators
    • A61M15/0028Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00Inhalators
    • A61M15/0028Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up
    • A61M15/003Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up using capsules, e.g. to be perforated or broken-up
    • A61M15/0033Details of the piercing or cutting means
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • A61P11/06Antiasthmatics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/48Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4841Filling excipients; Inactive ingredients
    • A61K9/4858Organic compounds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2202/00Special media to be introduced, removed or treated
    • A61M2202/06Solids
    • A61M2202/064Powder

Landscapes

  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Pulmonology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Anesthesiology (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Hematology (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Otolaryngology (AREA)
  • Dispersion Chemistry (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

El invento se refiere a cápsulas para inhalación (también conocidas como inhaletas) a base de materiales específicos para cápsulas con un contenido reducido de humedad, que contienen la sustancia activa tiotropio en forma de formulaciones pulverulentas, y que están caracterizadas por una estabilidad aumentada.
EC2003004868A 2001-06-01 2003-11-27 Cápsulas para inhalación ECSP034868A (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE10126924A DE10126924A1 (de) 2001-06-01 2001-06-01 Inhalationskapseln

Publications (1)

Publication Number Publication Date
ECSP034868A true ECSP034868A (es) 2004-03-23

Family

ID=7687020

Family Applications (2)

Application Number Title Priority Date Filing Date
EC2003004868A ECSP034868A (es) 2001-06-01 2003-11-27 Cápsulas para inhalación
EC2011004868A ECSP11004868A (es) 2001-06-01 2011-01-06 Capsulas para inhalación

Family Applications After (1)

Application Number Title Priority Date Filing Date
EC2011004868A ECSP11004868A (es) 2001-06-01 2011-01-06 Capsulas para inhalación

Country Status (37)

Country Link
EP (2) EP1379220B1 (es)
JP (3) JP4447311B2 (es)
KR (2) KR100921904B1 (es)
CN (3) CN101697965A (es)
AR (2) AR034346A1 (es)
AT (1) ATE285752T1 (es)
AU (2) AU2002344354B2 (es)
BG (1) BG65655B1 (es)
BR (1) BR0209366A (es)
CA (1) CA2448425C (es)
CH (1) CH1379220H1 (es)
CO (1) CO5540379A2 (es)
CZ (1) CZ300284B6 (es)
DE (2) DE10126924A1 (es)
EA (1) EA005188B1 (es)
EC (2) ECSP034868A (es)
EE (1) EE05416B1 (es)
EG (1) EG24227A (es)
ES (1) ES2236590B5 (es)
HR (1) HRP20030993B1 (es)
HU (3) HU230058B1 (es)
IL (2) IL158917A0 (es)
ME (1) ME00301B (es)
MX (1) MXPA03010990A (es)
MY (1) MY126253A (es)
NO (1) NO332857B3 (es)
NZ (1) NZ530356A (es)
PE (1) PE20030071A1 (es)
PL (2) PL203801B1 (es)
PT (1) PT1379220E (es)
RS (1) RS50353B (es)
SI (1) SI1379220T1 (es)
SK (2) SK287379B6 (es)
TW (1) TWI327921B (es)
UA (1) UA75659C2 (es)
WO (1) WO2002098874A2 (es)
ZA (1) ZA200308340B (es)

Families Citing this family (32)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ME00245B (me) 2000-10-12 2011-02-10 Boehringer Ingelheim Int Novi tiotropijumski preparati-koji sadrže prah za in haliranje
DE10126924A1 (de) * 2001-06-01 2002-12-05 Boehringer Ingelheim Pharma Inhalationskapseln
DE10212264A1 (de) 2002-03-20 2003-10-02 Boehringer Ingelheim Pharma Kristallines Mikronisat, Verfahren zu dessen Herstellung und dessen Verwendung zur Herstellung eines Arzneimittels
JP2005530765A (ja) * 2002-05-07 2005-10-13 ネクター セラピューティクス 乾燥粉末吸入器のためのカプセル及びそれを製造及び使用する方法
US7763280B2 (en) 2002-11-28 2010-07-27 Boehringer Ingelheim Pharma Gmbh & Co. Kg Tiotropium containing powder formulation for inhalation
DE10255387A1 (de) * 2002-11-28 2004-06-09 Boehringer Ingelheim Pharma Gmbh & Co. Kg Neue Tiotropium-haltige Pulverformulierung für die Inhalation
DE10258360A1 (de) * 2002-12-12 2004-06-24 Boehringer Ingelheim Pharma Gmbh & Co. Kg Pulverinhalator mit Kapselkammer zum Aufnehmen einer mit Wirkstoff gefüllten Einwegkapsel
DE10352277A1 (de) * 2003-11-08 2005-06-02 Boehringer Ingelheim Pharma Gmbh & Co. Kg Pulverinhalator
SE0303570L (sv) 2003-12-03 2005-06-04 Microdrug Ag Fukt-känslig medicinsk produkt
SE0303269L (sv) * 2003-12-03 2005-06-04 Microdrug Ag Medicinsk produkt
GB0503738D0 (en) 2005-02-23 2005-03-30 Optinose As Powder delivery devices
US7694676B2 (en) 2005-04-22 2010-04-13 Boehringer Ingelheim Gmbh Dry powder inhaler
JP4825455B2 (ja) * 2005-05-02 2011-11-30 ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング 粉末吸入器
DE102006016901A1 (de) * 2006-04-11 2007-10-25 Boehringer Ingelheim Pharma Gmbh & Co. Kg Mundstück für einen Inhalator
DE102006016904A1 (de) 2006-04-11 2007-10-25 Boehringer Ingelheim Pharma Gmbh & Co. Kg Inhalator
GB0716026D0 (en) 2007-08-16 2007-09-26 Norton Healthcare Ltd An inhalable medicament
DE102007036411A1 (de) 2007-07-20 2009-02-12 Boehringer Ingelheim Pharma Gmbh & Co. Kg Pulverinhalator
DE102007052871A1 (de) * 2007-11-02 2009-05-07 Boehringer Ingelheim Pharma Gmbh & Co. Kg Kapsel zur Aufnahme von pharmazeutischen Wirkstoffformulierungen
CA2714178A1 (en) * 2008-02-08 2009-08-13 Boehringer Ingelheim International Gmbh Method and device for filling capsules
EP2172190A1 (en) * 2008-10-02 2010-04-07 Laboratorios Liconsa, S.A. Inhalable particles comprising tiotropium
PT3578169T (pt) 2009-02-26 2024-07-29 Glaxo Group Ltd Formulações farmacêuticas compreendendo 4-{(1r)-2-[(2,6- diclorobenzil)oxi]etoxi}hexil)amino]-1-hidroxietil}-2- (hidroximetil)fenol
WO2010110760A1 (en) * 2009-03-27 2010-09-30 Mahmut Bilgic Compositions comprising water with deuterium for the prevention or treatment of allergic diseases and a process for the preparation thereof
GB0921075D0 (en) 2009-12-01 2010-01-13 Glaxo Group Ltd Novel combination of the therapeutic agents
WO2011152804A2 (en) 2010-06-03 2011-12-08 Mahmut Bilgic Process for dry powder formulations
DE202011102694U1 (de) 2011-06-29 2011-12-19 Zisser Gmbh Inhalationsgerät für Heimanwender
GB201200525D0 (en) 2011-12-19 2012-02-29 Teva Branded Pharmaceutical Prod R & D Inc An inhalable medicament
EA036153B1 (ru) 2012-07-05 2020-10-06 Арвен Айлак Санайи Ве Тиджарет А.С. Фармацевтическая композиция для ингаляции, упакованная дозированная форма, капсула, способ лечения обструктивных заболеваний дыхательных путей и фармацевтический набор
DE202013000774U1 (de) 2013-01-21 2013-04-15 Rhinofilt GmbH Miniaturisiertes Inhalationsgerät zur Privatanwendung
US10034866B2 (en) 2014-06-19 2018-07-31 Teva Branded Pharmaceutical Products R&D, Inc. Inhalable medicament comprising tiotropium
CN108295042A (zh) * 2018-03-05 2018-07-20 上海祺宇生物科技有限公司 一种用于吸入药剂的植物空心胶囊及其胶囊剂
CN108451920A (zh) * 2018-03-14 2018-08-28 绍兴康可胶囊有限公司 一种吸雾式胶囊及其制备方法
CN114848605B (zh) * 2022-03-25 2023-08-11 上海方予健康医药科技有限公司 一种供吸入粉雾剂用的明胶胶囊

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DE3931041C2 (de) * 1989-09-16 2000-04-06 Boehringer Ingelheim Kg Ester von Thienylcarbonsäuren mit Aminoalkoholen, ihre Quaternierungsprodukte, Verfahren zu ihrer Herstellung und diese enthaltende Arzneimittel
WO1993025193A1 (en) * 1992-06-12 1993-12-23 Teijin Limited Pharmaceutical preparation for intra-airway administration
US6228394B1 (en) * 1997-10-14 2001-05-08 Boehringer Ingelheim Pharmaceuticals, Inc. Supercritical fluid extraction of mould lubricant from hard shell capsules
DE19835346A1 (de) * 1998-08-05 2000-02-10 Boehringer Ingelheim Pharma Zweiteilige Kapsel zur Aufnahme von pharmazeutischen Zubereitungen für Pulverinhalatoren
JP2000143502A (ja) * 1998-11-11 2000-05-23 Shionogi Qualicaps Kk 吸入製剤
EP2266548B1 (de) * 1998-11-13 2020-05-20 Jagotec AG Trockenpulver zur inhalation
DE19921693A1 (de) * 1999-05-12 2000-11-16 Boehringer Ingelheim Pharma Neuartige Arzneimittelkompositionen auf der Basis von anticholinergisch wirksamen Verbindungen und ß-Mimetika
EP1072258A1 (de) * 1999-07-28 2001-01-31 Greither, Peter Eine Kapsel für die Freisetzung von Bakterien, enthaltend ein Bakterienlyophilisat und ein Verfahren zu ihrer Herstellung
CA2387212A1 (en) * 1999-10-12 2001-04-19 Kaken Pharmaceutical Co., Ltd. Dry powder inhalation and a method for the preparation thereof
DE10126924A1 (de) * 2001-06-01 2002-12-05 Boehringer Ingelheim Pharma Inhalationskapseln

Also Published As

Publication number Publication date
EP1379220B1 (de) 2004-12-29
NO332857B1 (no) 2013-01-21
BG108380A (en) 2004-11-30
CN1512875A (zh) 2004-07-14
WO2002098874A2 (de) 2002-12-12
MXPA03010990A (es) 2004-02-27
ZA200308340B (en) 2004-05-21
PL203801B1 (pl) 2009-11-30
NO332857B3 (no) 2016-01-25
PL387118A1 (pl) 2004-12-13
KR20090010140A (ko) 2009-01-28
PL364108A1 (en) 2004-12-13
NO20035265D0 (no) 2003-11-27
EG24227A (en) 2008-11-10
AU2008203057C8 (en) 2017-04-06
YU93503A (sh) 2006-05-25
AR084804A2 (es) 2013-06-26
HU230058B1 (hu) 2015-06-29
RS50353B (sr) 2009-11-10
MY126253A (en) 2006-09-29
KR100952321B1 (ko) 2010-04-09
SK16202003A3 (sk) 2004-05-04
CN101697965A (zh) 2010-04-28
AU2008203057C1 (en) 2017-05-18
JP2006143747A (ja) 2006-06-08
AU2002344354B2 (en) 2008-08-07
CA2448425C (en) 2010-12-21
ATE285752T1 (de) 2005-01-15
BR0209366A (pt) 2004-06-08
SK287346B6 (sk) 2010-07-07
PT1379220E (pt) 2005-03-31
IL158917A0 (en) 2004-05-12
EP1379220A2 (de) 2004-01-14
EP1508330A1 (de) 2005-02-23
EE05416B1 (et) 2011-06-15
HRP20030993A2 (en) 2005-08-31
NO20035265L (no) 2003-11-27
SK287379B6 (sk) 2010-08-09
HU231082B1 (hu) 2020-06-29
JP4447311B2 (ja) 2010-04-07
PE20030071A1 (es) 2003-03-04
KR20040007638A (ko) 2004-01-24
CN101829072A (zh) 2010-09-15
SI1379220T1 (en) 2005-04-30
NZ530356A (en) 2005-05-27
ES2236590T3 (es) 2005-07-16
ECSP11004868A (es) 2011-02-28
AR034346A1 (es) 2004-02-18
HU230827B1 (hu) 2018-07-30
UA75659C2 (en) 2006-05-15
HUP0400666A3 (en) 2009-06-29
JP2008050364A (ja) 2008-03-06
JP2005500279A (ja) 2005-01-06
PL205714B1 (pl) 2010-05-31
HRP20030993B1 (en) 2011-10-31
ME00301B (me) 2011-05-10
EA200301275A1 (ru) 2004-06-24
EE200300595A (et) 2004-02-16
MEP42508A (en) 2011-02-10
CA2448425A1 (en) 2002-12-12
KR100921904B1 (ko) 2009-10-16
WO2002098874A3 (de) 2003-09-12
JP4787034B2 (ja) 2011-10-05
EA005188B1 (ru) 2004-12-30
AU2008203057A1 (en) 2008-07-31
BG65655B1 (bg) 2009-05-29
IL158917A (en) 2008-11-03
DE50201898D1 (de) 2005-02-03
HUP1500188A2 (en) 2005-03-29
HUP0400666A2 (hu) 2005-03-29
CO5540379A2 (es) 2005-07-29
AU2008203057B2 (en) 2011-12-08
CZ300284B6 (cs) 2009-04-08
DE10126924A1 (de) 2002-12-05
CZ20033579A3 (en) 2004-05-12
CH1379220H1 (es) 2018-10-31
TWI327921B (en) 2010-08-01
ES2236590B5 (es) 2018-03-05

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