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EA201200537A1 - Способ получения глюкопиранозил-замещенных производных бензилбензола - Google Patents

Способ получения глюкопиранозил-замещенных производных бензилбензола

Info

Publication number
EA201200537A1
EA201200537A1 EA201200537A EA201200537A EA201200537A1 EA 201200537 A1 EA201200537 A1 EA 201200537A1 EA 201200537 A EA201200537 A EA 201200537A EA 201200537 A EA201200537 A EA 201200537A EA 201200537 A1 EA201200537 A1 EA 201200537A1
Authority
EA
Eurasian Patent Office
Prior art keywords
glucopiranosyl
benzylbenzene
obtaining
substituted derivatives
glucopyranosyl
Prior art date
Application number
EA201200537A
Other languages
English (en)
Other versions
EA022032B1 (ru
Inventor
Дирк Вебер
Тобиас Фидлер
Кристиан Фильзер
Райнер Хамм
Зимоне Орлих
Маттиас Пост
Свеня Реннер
Сяоюнь Ван
Томас Вирт
Original Assignee
Бёрингер Ингельхайм Интернациональ Гмбх
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Бёрингер Ингельхайм Интернациональ Гмбх filed Critical Бёрингер Ингельхайм Интернациональ Гмбх
Publication of EA201200537A1 publication Critical patent/EA201200537A1/ru
Publication of EA022032B1 publication Critical patent/EA022032B1/ru

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D309/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings
    • C07D309/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
    • C07D309/08—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D309/10—Oxygen atoms
    • C07D309/12—Oxygen atoms only hydrogen atoms and one oxygen atom directly attached to ring carbon atoms, e.g. tetrahydropyranyl ethers
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/26—Acyclic or carbocyclic radicals, substituted by hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D309/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings
    • C07D309/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
    • C07D309/08—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D309/10—Oxygen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H1/00—Processes for the preparation of sugar derivatives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H1/00—Processes for the preparation of sugar derivatives
    • C07H1/06—Separation; Purification
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H7/00—Compounds containing non-saccharide radicals linked to saccharide radicals by a carbon-to-carbon bond
    • C07H7/04—Carbocyclic radicals

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Saccharide Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Packaging Of Annular Or Rod-Shaped Articles, Wearing Apparel, Cassettes, Or The Like (AREA)
  • Wrapping Of Specific Fragile Articles (AREA)

Abstract

Настоящее изобретение относится способам получения глюкопиранозил-замещенного производного бензилбензола общей формулы IIIв которой Rотвечает определению согласно п.1 формулы изобретения.
EA201200537A 2009-09-30 2010-09-24 Способ получения глюкопиранозилзамещенных производных бензилбензола EA022032B1 (ru)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US24714409P 2009-09-30 2009-09-30
PCT/EP2010/064120 WO2011039108A2 (en) 2009-09-30 2010-09-24 Processes for preparing of glucopyranosyl-substituted benzyl-benzene derivatives

Publications (2)

Publication Number Publication Date
EA201200537A1 true EA201200537A1 (ru) 2012-11-30
EA022032B1 EA022032B1 (ru) 2015-10-30

Family

ID=43736212

Family Applications (1)

Application Number Title Priority Date Filing Date
EA201200537A EA022032B1 (ru) 2009-09-30 2010-09-24 Способ получения глюкопиранозилзамещенных производных бензилбензола

Country Status (25)

Country Link
US (2) US9024010B2 (ru)
EP (1) EP2486029B1 (ru)
JP (1) JP5758900B2 (ru)
KR (1) KR101813025B1 (ru)
CN (1) CN102574829B (ru)
AR (1) AR078193A1 (ru)
AU (1) AU2010303124B2 (ru)
BR (1) BR112012007085B8 (ru)
CA (1) CA2775962C (ru)
CL (1) CL2012000581A1 (ru)
DK (1) DK2486029T3 (ru)
EA (1) EA022032B1 (ru)
ES (1) ES2546762T3 (ru)
HR (1) HRP20150945T1 (ru)
HU (1) HUE026133T2 (ru)
IL (1) IL218101A0 (ru)
IN (1) IN2012DN02751A (ru)
MX (1) MX2012003048A (ru)
NZ (1) NZ598366A (ru)
PH (1) PH12012500634A1 (ru)
PL (1) PL2486029T3 (ru)
PT (1) PT2486029E (ru)
SI (1) SI2486029T1 (ru)
TW (1) TWI465458B (ru)
WO (1) WO2011039108A2 (ru)

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KR20120081592A (ko) 2012-07-19
US9024010B2 (en) 2015-05-05
IL218101A0 (en) 2012-04-30
PT2486029E (pt) 2015-10-14
AU2010303124B2 (en) 2014-01-23
KR101813025B1 (ko) 2017-12-28
EP2486029B1 (en) 2015-06-10
WO2011039108A2 (en) 2011-04-07
US20150218200A1 (en) 2015-08-06
CL2012000581A1 (es) 2012-08-03
HRP20150945T1 (hr) 2015-10-09
BR112012007085B1 (pt) 2020-10-13
WO2011039108A3 (en) 2011-05-26
EA022032B1 (ru) 2015-10-30
EP2486029A2 (en) 2012-08-15
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CA2775962C (en) 2017-09-05
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US20110237789A1 (en) 2011-09-29
AR078193A1 (es) 2011-10-19
HUE026133T2 (en) 2016-05-30
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CN102574829B (zh) 2015-07-01
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DK2486029T3 (en) 2015-08-24
BR112012007085B8 (pt) 2021-05-25
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